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CNN —Testing of over two dozen melatonin “gummies” sold as sleep aids found some had potentially dangerous amounts of the hormone that helps regulate sleep, according to a new study. “Four of the tested products contained levels of CBD that were between 4% and 18% higher than on the label,” Cohen said. “We choose gummies over other products because we thought parents would chose edibles to give to their children,” Cohen said. Gummies sold as sleep aids had much higher levels of melatonin than stated on the label, as well as CBD, according to the study. “However, that doesn’t mean melatonin products are going to work or they’re a good idea to take.
Months prior, Glaser and her team were implementing the school’s Covid-19 testing program, using antigen nasal swab tests. It’s not as simple as just handing those things out at school and having the kids do them,” said Glaser, who oversaw antigen testing programs at some California public schools. For now, Glaser and her colleagues described in a new study the lessons they learned from the Covid-19 dog screening pilot program that they launched in some California K-12 public schools. In comparison, Covid-19 BinaxNOW antigen tests have been shown in one real-world study to demonstrate 93.3% sensitivity and 99.9% specificity. The pilot program within California public schools also has left Edwards with hope for future opportunities in which canines can help detect disease in humans.
CNN —The outbreak of Covid-19 presented many dangers for children, and a new study suggests increased illicit substance ingestions were among them. Those numbers grew by 1.8% more per month than they did before the pandemic, the study said. The results could be skewed if health care providers were on the lookout for ingestions, Dodington added. There was no association between medicinal or recreational cannabis legalization and the rate of cannabis ingestion encounters, according to the study. Safer storageIngesting drugs and alcohol are particularly dangerous for young children, Dodington said.
CNN —A new study on breast cancer deaths raises questions around whether Black women should screen at earlier ages. Even though Black women have a 4% lower incidence rate of breast cancer than White women, they have a 40% higher breast cancer death rate. “When the breast cancer mortality rate for Black women in their 40s is 27 deaths per 100,000 person-years, this means 27 out of every 100,000 Black women aged 40-49 in the US die of breast cancer during one year of follow-up. They also wrote that health policy makers should pursue equity, not just equality, when it comes to breast cancer screening as a tool to help reduce breast cancer death rates. Having dense tissue in the breast can make it more difficult for radiologists to identify breast cancer on a mammogram, and women with dense breast tissue have a higher risk of breast cancer.
Schools with the highest rates of teens using prescribed ADHD medications were about 36% more likely to have students misusing prescription stimulants during the past year, the study found. Schools with more White students and those who had medium levels of student binge drinking were also more likely to see teen abuse of stimulants. “But these findings were not being driven solely by teens with ADHD misusing their medications,” McCabe said. Research has also shown people who misuse ADHD medications are highly likely to have multiple substance use disorders. “Parents can make sure the schools their kids attend have safe storage for medication and strict dispensing policies.
CNN —Treating hearing loss could mean reducing the risk for dementia, according to a new study. Hearing loss may increase the risk for dementia, but using hearing aids lowered the risk so it’s similar to those without hearing loss, according to the study published Thursday in The Lancet. A 2020 Lancet commission on dementia prevention, intervention and care suggested hearing loss may be associated with around 8% of dementia cases, but this study found that the use of hearing aids reduced the risk to levels similar to people without hearing loss, the study said. “A recent study showed that only 15% of US adults with hearing loss use hearing aids,” De Sousa said. The Hearing Loss Association of America still supports multiple avenues for addressing hearing loss, Hamlin said.
A Little Alcohol Won’t Kill You or Make You Stronger
  + stars: | 2023-03-31 | by ( Julie Wernau | ) www.wsj.com   time to read: 1 min
A new study published on Friday joins a body of evidence that shows alcohol does more harm than good. First, the good news: A nip of alcohol here and there probably won’t kill you. For a study published Friday in the journal JAMA Network Open, researchers set out to make sense of years of conflicting evidence on alcohol’s effect on health. Some research suggested that drinking alcohol improves life expectancy. Other studies had demonstrated poorer health outcomes at any level of drinking.
(Photo by Rachel Wisniewski/For the Washington Post)People who take Pfizer 's Covid antiviral treatment Paxlovid shortly after infection may reduce their risk of developing long Covid, regardless of their age, vaccination status or infection history, new research suggests. The study, published in the journal JAMA Internal Medicine on Thursday, found that people who took Paxlovid within five days of a positive Covid test saw a 26% lower risk of long Covid compared with those who didn't receive it. The new study comes as researchers work to fill the knowledge gap about long Covid, an often debilitating condition with limited data and no proven treatment available. Long Covid refers to new, returning or ongoing health issues more than four weeks after an initial Covid infection, according to the Centers for Disease Control and Prevention. She called the new study "very exciting and promising" because it's the first to show an association between Paxlovid and a decreased risk of long Covid.
A new paper that analyzed data from 41 studies found that exercise had a big effect on depression. Researchers found that exercise improved depression symptoms at least as much as other treatments. They said that exercise should be offered as "an evidence-based treatment option" for patients. Aerobic exercise and resistance training had big effects on reducing depression symptoms, the authors noted, as did supervised and group exercises of "moderate intensity." A 2018 study published in JAMA Psychiatry found that strength training can help treat depression just as well as aerobic exercise.
Offering cake as well as other sweets and snacks may protect against dysfunctional eating behaviors. Crystal Karges celebrated her youngest daughter’s fifth birthday last month with a gooey chocolate cake covered in white frosting and rainbow sprinkles. The next morning, she served her five children the leftover slices at breakfast alongside fruit, eggs, sausage and milk. Ms. Karges is among parents, dietitians and doctors who advocate giving children more freedom over what they eat including, at times, high-sugar, high-fat and highly processed foods. They said the approach helps children develop healthy dietary habits and protect against disordered eating—or dysfunctional eating behaviors—which affects more than 20% of children globally, according to a recent meta-analysis in the journal JAMA Pediatrics.
Offering cake as well as other sweets and snacks may protect against disordered eating. Crystal Karges celebrated her youngest daughter’s fifth birthday last month with a gooey chocolate cake covered in white frosting and rainbow sprinkles. The next morning, she served her five children the leftover slices at breakfast alongside fruit, eggs, sausage and milk. Ms. Karges is among parents, dietitians and doctors who advocate giving children more freedom over what they eat including, at times, high-sugar, high-fat and highly processed foods. They said the approach helps children develop healthy dietary habits and protect against disordered eating, which affects more than 20% of children globally, according to a recent meta-analysis in the journal JAMA Pediatrics.
And two Congressional bills addressing the long Covid crisis — The “Covid-19 Long Haulers Act,” which would’ve collected data on long Covid patients with the goal of creating better care and treatment, and “The Care For Long Covid Act” would’ve improved research, centralized data and resources for people with Long Covid — died without making it out of committee. Disabled by long Covid since March 2020, she lives with her spouse and their 7-year-old son in Portland, Ore. “We didn’t design our life to be a single-income household.”Other long Covid patients have rearranged their finances, too. His company’s private long-term disability insurance pays a smaller percentage of the monthly benefit payout when federal disability pays a portion. “They’re not only dealing with long Covid complications, but they’re dealing with financial complications,” she said of her clients.
The Wild World Inside Your Gut
  + stars: | 2023-02-22 | by ( Alice Callahan | ) www.nytimes.com   time to read: +20 min
The Wild World Inside Your GutWe tackled everything from heartburn, stress, spicy foods and colon cleanses to antibiotics and more. So grab a kombucha, get comfortable and read on for everything you’ve wanted to know about the wild world inside your gut. 3 What are some simple things I can do to improve my gut health? That “really is going to have the strongest impact on our health, including gut health,” she said. (Though for general gut health, Dr. Rao said, most people living in the United States could benefit from eating fewer refined carbohydrates and more fiber.)
Philip O'Keefe, one of Synchron's patients in the SWITCH clinical trial, using his BCI. Philip O'Keefe, one of Synchron's patients in the SWITCH clinical trial, was the first person in the world to tweet using a BCI device. About 20 months earlier, O'Keefe was implanted with Synchron's BCI. Synchron's technology has caught the attention of its competitors. Source: SynchronIn January, the medical journal JAMA Neurology published the peer-reviewed, long-term safety results from a trial of Synchron's BCI system in Australia.
Mounting cyberattacks against hospitals and clinics and a regulatory push are increasing the pressure on medical-device manufacturers to improve the security of their products. Cyber protections have often been an afterthought for medical devices, which can be in operation for decades. Newsletter Sign-up WSJ Pro Cybersecurity Cybersecurity news, analysis and insights from WSJ's global team of reporters and editors. While Mr. Suarez acknowledged that greater transparency about vulnerabilities is needed from makers of medical devices, he also wants to see customers stop using old, unsupported equipment. “It’s a complex challenge,” Mr. Suarez said.
"Everybody has a different amount of fibroglandular tissue and a different pattern," Freer said, referring to dense breast tissue. In individual interviews as part of Gunn's survey, six out of 61 women said dense breasts contributed to breast cancer risk. There are two reasons dense breasts are linked to a higher risk of breast cancer. To lower one's risk of breast cancer overall, doctors recommend limiting alcohol intake, exercising regularly and maintaining a healthy diet. The Breast Cancer Surveillance Consortium offers an online tool to help people gauge their breast cancer risk based on multiple factors, including breast density.
A provision in the Inflation Reduction Act that allows Medicare to negotiate prices on the costliest prescription drugs each year will likely save the U.S. billions of dollars — as long as the drug industry doesn't interfere, according to a study published Friday in JAMA Health Forum. They identified 40 drugs that would have been selected by Medicare for drug pricing negotiation under the Inflation Reduction Act's provision. The researchers simulated negotiated prices by using a so-called ceiling price, which is at least 25% off the average price drug manufacturers charge to nongovernment entities, like private health insurance providers. The researchers found that the Medicare drug negotiation provision would have saved the U.S. $26.5 billion, or 5% of all drug spending, during those three years. It plans to release a list of the first 10 drugs it will target for drug pricing negotiation by September.
A board-certified dermatologist said doctors still don't know the risks UV lamps used for gel manicures pose. Gel manicures only expose the skin to UV light for a short time, but frequent exposure may have long-term consequences. The dermatologist said to wear sunscreen and fingerless gloves to limit your UV light exposure. Similarly, a previous study published in JAMA in 2014 suggested the carcinogenic risk from UV lamps is too small to stop people from getting their nails done. Consider bringing fingerless gloves and sunscreen to the nail salonApplying sunscreen to your fingers and hands can help protect them from UV exposure.
The infusions at the ketamine clinic in his West Texas hometown were a Christmas gift from his grandmother. About five years ago, more and more of my friends started using ketamine recreationally. IV ketamine treatment centers charging $400 to $2,000 an infusion popped up all over the country. "Ketamine used as directed in an appropriate clinical setting very rarely leads to any dependence," Mindbloom says on its website. Like Nadia, most of the people I interviewed said when they started using ketamine, they didn't think it was possible to become dependent on it.
U.S. new drug price exceeds $200,000 median in 2022
  + stars: | 2023-01-05 | by ( Deena Beasley | ) www.reuters.com   time to read: +3 min
The median annual price of the 17 novel drugs the U.S. Food and Drug Administration (FDA) approved since July 2022 is $193,900, down from $257,000 in the first half of 2022, Reuters found. For full year 2022, the median was $222,003. Reuters Graphics Reuters GraphicsIn 2021, the median annual price was $180,000 for the 30 drugs first marketed through mid-July, according to a study published recently in JAMA. Health insurers and other payers often demand discounts and rebates for prescription drugs once competing treatments become available. As patents expire, lower-cost generics also mitigate prescription drug price inflation, which in the 12 months through November 2022 was 1.9%, according to the Bureau of Labor Statistics.
Exercise Can Help Children With Symptoms of Depression
  + stars: | 2023-01-04 | by ( Sarah Toy | ) www.wsj.com   time to read: 1 min
School closures, social isolation and other hardships during the peak years of the Covid pandemic have hurt young people’s mental health. Regular exercise can alleviate symptoms of depression in children, a new analysis showed. International researchers who published their analysis this week in JAMA Pediatrics reviewed 21 studies to determine whether physical activity was associated with a decline in depressive symptoms in children. In the studies, which included data from more than 2,400 young children and adolescents, exercise sessions encompassed activities including sports and simple aerobics such as running or jumping.
How much does insulin cost? People with Type 1 diabetes need, on average, one to three vials of insulin per month, according to the American Diabetes Association. Patients with Type 2 diabetes don't always need to take insulin, but those who do can sometimes require more than people with Type 1 diabetes. Even people with what's considered good health insurance coverage can face steep costs in certain situations. In addition to insulin and insurance premiums, Gibson also must spend $550 every three months for glucose monitors and $1,100 for insulin pumps.
A study published Wednesday in JAMA Psychiatry found that abortion restrictions may have played a role in some suicide deaths among younger women from 1974 to 2016. The study is the first of its kind to show an association between abortion restrictions and suicide rates among younger women, said Dr. The researchers did not find the same association for older women, he said, suggesting that the increased suicide risk was specific to women directly affected by TRAP laws. Elevated suicide rates in states with more restrictive abortion laws "is cause for clinical concern," he wrote. That research ended in 2016, though, so it's unclear how newer abortion restrictions — such as the Supreme Court decision to overturn Roe v. Wade — have affected suicide rates among younger women.
So the Health Department conducted something called an online “sentiment search,” which gauges how certain words are perceived on social media. An analysis conducted by KHN and The Associated Press found local health department spending dropped by 18% per capita from 2010 to 2020. To that end, the health department has partnered with local leaders and groups to encourage vaccinations. — Phil Maytubby, Oklahoma city County health departmentThe more than 3,000 public health departments nationwide stand to benefit from a unified message, he said. In late 2020, the foundation, working with other public health groups, established the Public Health Communications Collaborative to amplify easy-to-understand information about vaccines.
This week, the FBI issued a rare public safety alert warning of an alarming increase in “sextortion” cases targeting children and teens. One former investigator with the New Jersey State Police reported that sextortion cases have increased 400% in the last four years. One told a 13-year-old he would rape her and kill her parents if she didn’t perform certain sexual acts on camera. Tell kids to be highly selective about sharing any personal information and to never, ever share intimate images online. And anytime a child is blackmailed or extorted for sexual images, that should be reported to law enforcement.
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