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If successful, Merck could begin marketing the new formulation within a few years, a top Merck executive told Reuters. "The clock for that patent would start ticking from the time we would get that patent approved." Drug patents have a guaranteed term of exclusivity for 20 years after receiving a patent under U.S. law, but sometimes the companies are able to add additional patents that extend their exclusivity. Merck's patents on the subcutaneous version of Keytruda could protect that formulation until at least 2040, according to Tahir Amin, co-founder of drug patents watchdog group Initiative for Medicines, Access & Knowledge (I-MAK). Northwell's Mulloy said moving patients to subcutaneous versions of drugs also opens up spots in infusion centers for additional patients.
Pallava Bagla | Corbis News | Getty ImagesVenture capitalists in Silicon Valley and other tech hubs are investing money in nuclear energy for the first time in history. This surge of private investment will be a positive for the industry, agrees John Parsons, an economist and lecturer at MIT. Nuclear energy is "a very complex science, and it's been supported by the federal government and at these national labs. In the 1960s and 1970s, large conglomerates constructed big nuclear power plants, and those projects often ran over budget. New generations of nuclear reactors will have different sizes, different coolants and different fuels, explained Matt Crozat, senior director of policy development at the Nuclear Energy Institute.
Rats are taking refuge in cars, chewing through wires and leaving owners with big repair bills. There are three things you can do to help prevent rats from living under the hood of your car. Do not park above or near storm drain basins or openings to sewers – Norway rats are called sewer rats for a reason. One woman told The Times that a rat chewed through a sensor wire in her car, which cost $700 to fix. "What they're doing is inadvertently attracting rats or other rodents onto the property," he said.
Gary McCullough/AP Green Bay Packers wide receiver Samori Toure is tackled by Detroit Lions safety Will Harris. Norm Hall/Getty Images Buffalo Bills quarterback Josh Allen hurdles Kansas City Chiefs safety Justin Reid as he scrambles for a first down. Gary A. Vasquez/USA Today Sports/Reuters New Orleans Saints wide receiver Michael Thomas makes a reception against Atlanta Falcons cornerback A.J. To see if history repeats itself with a Cowboys win, or if the Giants can pull off the upset, tune in on Thursday at 4:30 p.m. Bill Belichick’s team could be on the cusp of a hot streak and are hitting the Vikings game at just the right time.
[1/5] View of the entrance to the condominium complex ONE Cable Beach, a beachfront residence in New Providence, Bahamas, November 18, 2022. The deeds show these properties, bought by a unit of FTX, were to be used as "residence for key personnel" of the company. PROPERTY PURCHASESReuters searched property records at the Bahamas Registrar General's Department for FTX, Bankman-Fried, his parents and some of the company's key executives. FTX Property Holdings Ltd, an FTX unit, bought 15 properties worth nearly $100 million in 2021 and 2022. The property records for the penthouse, dated March 17, were signed by Ryan Salame, the president of FTX Property, and showed it was intended as "residence for key personnel."
The deeds show these properties, bought by a unit of FTX, were to be used as "residence for key personnel" of the company. Reuters could not determine the source of funds that FTX and its executives used to buy these properties. PROPERTY PURCHASESReuters searched property records at the Bahamas Registrar General's Department for FTX, Bankman-Fried, his parents and some of the company's key executives. FTX Property Holdings Ltd, an FTX unit, bought 15 properties worth nearly $100 million in 2021 and 2022. The property records for the penthouse, dated March 17, were signed by Ryan Salame, the president of FTX Property, and showed it was intended as "residence for key personnel."
NFL roundup: Joe Burrow helps Bengals get revenge vs. Steelers
  + stars: | 2022-11-21 | by ( ) www.reuters.com   time to read: +10 min
Both of Herbert's touchdown passes were caught by Joshua Palmer, who finished with eight catches for 106 yards. Quarterback Marcus Mariota paced Atlanta's offense with 131 passing yards, a passing touchdown and a rushing touchdown. Hurts finished with 190 passing yards and 86 passing yards. Saints 27, Rams 20Andy Dalton threw three touchdown passes as host New Orleans defeated Los Angeles, which lost Matthew Stafford to a possible concussion. Kirk Cousins was ineffective in the passing game, totaling 105 yards through the air while completing 12 of 23 passes.
Russia's suspension was passed by 64 votes to 39, with 16 abstentions, at the IPC's extraordinary General Assembly in Berlin on Wednesday. "Due to their suspension, NPC Russia and NPC Belarus lose all rights and privileges of IPC membership, in accordance with the IPC Constitution," the IPC said in a statement. "Both NPC Russia and NPC Belarus now have the right to appeal the decision. The next IPC General Assembly is due to take place in the final quarter of 2023 at a venue yet to be confirmed." The Russian Paralympic Committee called the IPC decision unfounded.
Tech companies that proactively reacted to consumer and enterprise demands came out ahead this year. 100 People Transforming Business is an annual list highlighting people across industries who are changing the way the world does business. The emerging technology leaders featured on Insider's annual "100 People Transforming Business" list have stepped up to do just that. Virtual-whiteboard platforms are seen as an essential workplace tool that some predict are set to stay a popular tool in business tech. Tech transparency becomes a talking point across platformsAt home, this year showed that tech consumers wanted more transparency.
A UN study last year found "negligible" correlation between household food waste and gross domestic product, indicating most countries "have room to improve." "We do have a long way to make the goal," said Jean Buzby, the food waste liaison at the U.S. Department of Agriculture. The USDA, the Environmental Protection Agency and the Food and Drug Administration agreed in 2018 to tackle America's food waste together. A spokesman for New Zealand's environment ministry said the country is finalizing its baseline food waste estimate so it can establish a target. SLOWEST GAZELLEIn California, which has America's most ambitious climate policies, officials are trying to ensure food waste goes to composting, not landfills.
Today's EVs run on lithium ion batteries — mostly made with lithium, cobalt, manganese and high-grade nickel, whose prices have soared. The EVs of the future — those arriving after 2025 — could shift to sodium ion or lithium sulfur battery cells that could be up to two-thirds cheaper than today's lithium ion cells. China's CATL (300750.SZ) has said it plans to begin producing sodium ion cells in 2023. Michigan-based Amandarry and British startup AMTE Power (AMTE.L) are developing sodium ion batteries using sodium chloride — basically table salt — as the main cathode ingredient. Battery developers hope they can add sodium ion and lithium sulfur batteries to the range open to the auto industry.
Gary McCullough/AP Green Bay Packers wide receiver Samori Toure is tackled by Detroit Lions safety Will Harris. Norm Hall/Getty Images Buffalo Bills quarterback Josh Allen hurdles Kansas City Chiefs safety Justin Reid as he scrambles for a first down. Allen's fourth quarter touchdown throw to Dawson Knox capped off a 24-20 victory against the Chiefs. Marcio Jose Sanchez/AP Minnesota wide receiver Justin Jefferson dives for a two-point conversion during the Vikings' 29-22 victory over the Chicago Bears. Gary A. Vasquez/USA Today Sports/Reuters New Orleans Saints wide receiver Michael Thomas makes a reception against Atlanta Falcons cornerback A.J.
The American Firearms Association says its members favor Ron DeSantis over Donald Trump for president. Ron DeSantis for the 2024 presidential election. The American Firearms Association, citing a poll of its members, announced Friday nearly 69% favor DeSantis for president compared to nearly 29% for Trump. Their survey results in March were reversed, according to the group — nearly 67% for Trump and about 21% for DeSantis. The group posed the question to its 2,000-plus followers on Twitter Thursday: "Who do you support for President: Donald Trump, Ron DeSantis, or someone else?"
[1/2] Republican candidate for Michigan Secretary of State Kristina Karamo campaigns in Clinton Township, Michigan, U.S. November 4, 2022. Democratic President Joe Biden narrowly won Michigan, Arizona and Nevada in 2020 and Trump and his allies have falsely claimed that the results were fraudulent. As of Wednesday, States Action United said 13 election deniers had won a statewide role in election administration in 9 states, while 24 election deniers had lost races in 17 states. The races in Michigan, Arizona and Nevada are particularly important because they are key battleground states. Ahead of Tuesday's elections, Biden accused Trump of inspiring Republican election denier candidates and warned voters: "Democracy is on the ballot for all of us."
Michigan voters passed a constitutional amendment known as Proposal 3 that enshrines the right to an abortion by nearly 55%, according to Edison Research. The victories for abortion rights suggested that voters of all political stripes are balking at the severe abortion restrictions that several Republican-led states have enforced since the U.S. Supreme Court gutted federal abortion rights in June. The outcomes of the ballot questions, particularly in a swing state like Michigan, could set the stage for future state campaigns to proactively reinstate abortion rights. The mood was jovial as the "yes" votes on the Michigan amendment outpaced "no" votes across the state. Michigan Reproductive Freedom For All, a coalition of reproductive rights and progressive groups, led the petition to get the amendment on the ballot.
In August, voters in conservative Kansas defeated a ballot measure aimed at eliminating abortion rights from the state's constitution. MICHIGANVoters in the battleground state of Michigan backed a ballot initiative declaring abortion as a right protected by the state's constitution. VERMONTVoters decided to include abortion rights in Vermont's state constitution. As required by state law, the ballot measure had already been approved twice by the Democratic-controlled legislature. Other conservative states have enacted similar legislation in recent years.
Republican state attorney general Eric Schmitt is running against Democrat Trudy Busch Valentine to represent Missouri in the US Senate. Missouri's US Senate race candidatesSchmitt serves as the attorney general of Missouri, a position he was appointed to by Republican Gov. Mike Parsons following former Attorney General Josh Hawley's election to the US Senate. Prior to being appointed attorney general, Schmitt served as state treasurer and state senator. His opponent, Valentine, has raised $12 million, spent $11.6 million, and has $327,578 cash on hand, as of October 19.
The broken commitment, which has not previously been reported, highlights the struggles of Mexico's oil regulator to rein in Pemex, a powerful state monopoly that is always closely connected to the government. The oil company has in recent quarterly reports stressed it was making efforts to clean up its operations and bring down flaring and other waste. Earlier this year, under increasing international criticism, Lopez Obrador said Pemex would invest $2 billion to improve infrastructure to reduce flaring and methane emissions. The regulator said in 2020 the company wasted 37.7% of the gas from Ku alone through flaring, venting or otherwise. One source said the regulator fined Pemex again for recurrence in 2021 but the oil company started legal proceedings to annul the fine, which are still pending.
Norm Hall/Getty Images Buffalo Bills quarterback Josh Allen hurdles Kansas City Chiefs safety Justin Reid as he scrambles for a first down. Marcio Jose Sanchez/AP Minnesota wide receiver Justin Jefferson dives for a two-point conversion during the Vikings' 29-22 victory over the Chicago Bears. Gerald Herbert/AP Indianapolis Colts wide receiver Michael Pittman Jr. is tripped up by Denver Broncos cornerback K'Waun Williams. David Richard/AP Tampa Bay Buccaneers wide receiver Breshad Perriman fumbles after catching a pass during the first half against the Green Bay Packers in Week 3. Gary A. Vasquez/USA Today Sports/Reuters New Orleans Saints wide receiver Michael Thomas makes a reception against Atlanta Falcons cornerback A.J.
Here are some of the main stakeholders and negotiating blocs engaged in the U.N. climate conference (COP27) that starts on Nov. 6 in Sharm el-Sheikh, Egypt. A diplomatic row over Taiwan led Beijing to cancel bilateral climate talks with the United States. EUROPEAN UNIONGreenhouse gas emissions from the 27-country European Union comprise about 8% of the global total, and have been trending downward for years. Negotiating as a single group at the U.N. climate talks, the EU intends to push other major emitters to raise their targets. Meanwhile, long-time climate champion King Charles III said he will skip the COP27 conference in Egypt.
OTTAWA, Nov 3 (Reuters) - Canada will introduce refundable tax credits for clean technologies worth up to 30% of investment costs, in a bid to close competitive gaps with the United States in scaling up green technologies, the government said on Thursday. The clean-tech tax credits will be offered for investors in net-zero technologies, battery storage and clean hydrogen, according to the so-called fall economic statement (FES) presented to the House of Commons by Finance Minister Chrystia Freeland. The tax will generate an estimated C$2.1 billion over five years and will come into force on Jan 1, 2024. "In terms of trying to foster business investments, I don't think it's well targeted," said Robert Asselin, senior vice president of policy at the Business Council of Canada. In next year's budget, Canada will introduce new measures to increase advanced manufacturing competitivness, the document said.
SANTIAGO, Nov 3 (Reuters) - Chile's total copper production fell 4.27% in September to 428,300 tonnes, government body Cochilco said on Thursday. Production from state-owned giant Codelco fell 7.92% on a year-on-year basis to 123,200 tonnes, while production at Collahuasi, a joint venture of Anglo American (AAL.L) and Glencore , fell 3.5% to 44,500 tonnes. Copper output from Escondida, which is controlled by Australian mining giant BHP (BHP.AX), rose 3.51% to 85,500 tonnes, Cochilco said. Reporting by Natalia Ramos; editing by Jonathan OatisOur Standards: The Thomson Reuters Trust Principles.
But on the gaming platform Roblox, users can adorn their digital avatar with a Lola handbag for just under $10. Three out of 4 were willing to spend money on digital fashion, with one in 4 admitting to spending between $20 to $100 on a single item. She believes that number is going to continue increasing as the digital fashion space evolves. RobloxBy 2030, the digital fashion space is poised to be worth $50 billion, according to projections by Morgan Stanley. There are more than 100 brands that have created handbags, shoes, and other clothing items for Roblox, according to Wootton.
Petithomme goes by the alias Ti Makak, and leads a gang of the same name. Haiti's National Police did not respond to requests for comment on the police commissary incident or about Ti Makak in general. Local media reported that Ti Makak was responsible. But the calls continued, he said, and a group later arrived in person, saying they were linked to Ti Makak. "We can easily conclude that the Ti Makak band seeks to win the hearts of the people, particularly of those people who have been involved in acts of looting during recent protests," Germain said.
Marc Evan started Maniac Pumpkin Carvers with his childhood friend after graduating from college. I run Maniac Pumpkin Carvers, which I started in 2008 with my childhood friend Chris Soria after graduating from college. We were really taking a nostalgic pastime like pumpkin carving that we did at home as kids and elevating it into an art form. Courtesy of Maniac Pumpkin CarversWord about us got out after Wired did an article on us in 2009. Courtesy of Maniac Pumpkin CarversThe farmers market Union Square Greenmarket in downtown Manhattan was home base for us for a very long time.
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