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Search resuls for: "Therapeutic"


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The Many Mustaches of Kenneth Branagh’s Hercule Poirot
  + stars: | 2023-09-15 | by ( Calum Marsh | ) www.nytimes.com   time to read: +1 min
“It was my ritual every night after the shoot,” Yoshihara said recently in a video interview. “Me and the mustache sit together. The mustache became like a friend.”Yoshihara takes facial hair very seriously. The first iteration of Branagh’s Poirot mustache was created for “Orient Express” by the designer Carol Hemming, with whom Yoshihara worked closely as the head of the hair and makeup departments. The colossal gray swath of hair was meant to pay tribute to Poirot’s military background and the vogue after World War I.
Persons: Kenneth Branagh, Agatha Christie’s Hercule Poirot, Wakana Yoshihara, ” Yoshihara, , , Branagh, Yoshihara, Carol Hemming Organizations: Orient Express, “ Orient Locations: Venice
Maker of MDMA-assisted PTSD treatment to seek US regulatory nod
  + stars: | 2023-09-15 | by ( ) www.reuters.com   time to read: +2 min
A woman retrieves items from the rubble of her destroyed home after a wildfire came through the area in Talent, Oregon, Oregon, U.S. September 21, 2020. PTSD is a disorder caused by very stressful events and can significantly disrupt patients' lives. While PTSD is commonly associated with combat, civilians are not immune to it. Psychoactive ingredients, whether derived from cannabis, LSD or magic mushrooms, have long captivated mental health researchers in their quest for treatments. MAPS, founded in 1986, said it hopes the MDMA-assisted therapy will be approved next year and inspire other researchers studying therapeutic psychedelics.
Persons: Jim Urquhart, Manas Mishra, Pooja Desai Organizations: REUTERS, Multidisciplinary Association for Psychedelic Studies, U.S . Food, Drug Administration, Thomson Locations: Talent , Oregon , Oregon, U.S, United States, Bengaluru
Epic Healing Eugene — Oregon’s first licensed psilocybin service center — opened in June, marking the state’s unprecedented step in offering the mind-bending drug to the public. The clients can't buy mushrooms to go, and they must stay at the service center until the drug wears off. Oregon Psilocybin Services spent two years establishing regulations and began accepting license applications in January. She expects Oregon’s psilocybin program, currently receiving millions in taxpayer dollars, to be fully supported by licensing fees by mid-2025. Little, brown psychedelic mushrooms can be found growing in fields or in the woods, but they can closely resemble poisonous varieties.
Persons: Eugene — Oregon’s, Angela Allbee, , ” Allbee, It’s, Eugene, Brian Lindley, Jeanette Small, Allbee, Cathy Jonas, Jonas, , Gared Hansen, Hansen, " Hansen, that’s Organizations: Food and Drug Administration, FDA, Oregon Psychiatric Physicians Association, Services, Ashland, Service Locations: EUGENE, Eugene, Colorado, Oregon, United States, Bend, San Francisco, Springfield , Oregon, Pink Buffalo
LONDON (AP) — Ian Wilmut, the cloning pioneer whose work was critical to the creation of Dolly the Sheep in 1996, has died at age 79. While Dolly's creation was heralded as a revolution by some scientists, it unnerved many, with critics calling such experiments unethical. Wilmut, a trained embryologist, later focused on using cloning techniques to make stem cells that could be used in regenerative medicine. Whitelaw described Wilmut as a “titan” of science and said his work in Dolly's creation transformed scientific thinking at the time. He said the legacy of Wilmut's work in cloning Dolly continues to be seen.
Persons: Ian Wilmut, Dolly, Wilmut, Dolly Parton, Bill Clinton, Sir Ian Wilmut, Bruce Whitelaw, Whitelaw, Organizations: University of Edinburgh, biosciences, Roslin Locations: Scotland
At first, I focused a lot of the content on microdosing, which I had done with LSD while living in Thailand. AdvertisementAdvertisementIn my opinion, a misconception is that psychedelics don't work to aid mental health. I don't work with people interested in trying psychedelics to heal post-traumatic stress disorder or depression because I'm not a clinician. If someone is coming to you as a coach to work with psychedelics, they may, for example, be struggling with relationships. The challenge isn't necessarily that I'm worried about being arrested but more about the limitations on what I can do.
Persons: Paul Austin, Dr Peter Grinspoon, I've, psychedelics, I'm Organizations: Service, Massachusetts General Hospital, Harvard Medical School Locations: Wall, Silicon, Massachusetts, Thailand
Weight loss drugs are being assessed for their ability to treat conditions like dementia and addiction after a landmark study showed that Wegovy helped reduce the risk of heart attacks and strokes. Late-stage trial data released last month by Novo Nordisk indicated that its Wegovy weight loss injection led to "large reductions" in heart failure-related symptoms among at-risk patients. A treatment for drug and alcohol abuseHendershot is one researcher investigating whether the appetite-regulating mechanisms at play in weight loss drugs could be used to treat other conditions such as alcohol and drug addiction. Novo Nordisk's Wegovy and Eli Lilly 's Mounjaro work by imitating a naturally occurring gut hormone that helps regulate appetite in the brain, ultimately leading to weight loss. Implications for reward signalingAdditional possible use cases for weight loss drugs could exacerbate the hurdles already faced by patients using them, however: high costs and supply shortages.
Persons: Wegovy, , Hendershot, Nordisk's Wegovy, Eli Lilly, Kyle Simmons, Simmons, Ivan Koychev, Harshal Deshmukh Organizations: Bloomberg, Getty, Novo Nordisk, University of North, Chapel Hill, CNBC, Nordisk's, Oklahoma State, Oklahoma State University, University of Baltimore, University of Oxford, University of Hull Locations: Danish, University of North Carolina, Chapel
His experience inspired him to focus his investment firm on backing psychedelic startups. But VCs, including Smith, are still betting big on startups in the space that seem especially promising. It wasn't until he tried psychedelics — including Ayahuasca, a plant-derived hallucinogenic drink, and iboga, an African root bark — that his mental health finally improved. Energized by his own experience, Smith reworked his cannabis-focused VC firm Ultranative into a one-stop-shop for psychedelic startups. Smith and Ultranative are far from the only investors pumping money into psychedelic startups.
Persons: Ford Smith, wean, South America —, Ayahuasca, Ultranative, Smith, didn't, Lyme, psychedelics, Rick Doblin, he's Organizations: innovating, Venture, Anonymous, Multidisciplinary Association for Psychedelic Studies, pharma, FDA, PsyMed Ventures, Lionheart Ventures, Iter Investments, Neo Kuma Ventures, Therapeutics Locations: Austin, South America, U.S, Oregon, Colorado, psychedelics, Texas, Los Angeles, Massachusetts
Amgen has a promising growth outlook despite facing a "substantial patent cliff," according to HSBC. While some very old products are finally facing patent cliffs it will likely be gradual and a broadened portfolio allows for continued growth," analyst Morten Herholdt wrote in a Wednesday note. Amgen is set to lose exclusivity on patents for drugs that make up about three-quarters of the company's sales. The company's acquisition of Horizon Therapeutics will also help it extend sales and pipeline into the rare diseases market, Herholdt added. Due to the current investor skepticism with the looming patent cliff, Amgen shares are trading at an "undemanding" earnings multiple, according to the analyst.
Persons: Amgen, Morten Herholdt, Herholdt, , Michael Bloom Organizations: HSBC, Horizon Therapeutics Locations: Tuesday's
The California bill would make gender affirmation one factor among many that courts already have to consider in custody proceedings, including whether a parent has been abusive and how much contact the child has with the parents. The bill would not require judges to prioritize whether a parent affirms their child's gender identity over other factors. The state Senate passed the resolution, and it now heads to the Assembly. State Sen. Shannon Grove, a Republican from Bakersfield, said she didn’t think other states would agree to that. The bipartisan California bill would not legalize the sale of the drugs.
Persons: Democratic Sen, Scott Wiener, they’ve, ” Wiener, , Sen, Kelly Seyarto, ” Seyarto, Gavin Newsom, Assemblymember Lori Wilson, Wilson, , Alexis Sanchez, Sanchez, Newsom, Aisha Wahab, Wiener, State Sen, Shannon Grove, DECRIMINALIZING, it’s, Bill Essayli, Adam Beam, Nguyễn, ___ Sophie Austin, Austin @sophieadanna Organizations: Democratic, Republican, Democratic Gov, Sacramento LGBT Community Center, San Francisco, State, ., Associated Press, America Statehouse News Initiative, America Locations: SACRAMENTO, Calif, California, San Francisco, Southern California, U.S, Bakersfield, DECRIMINALIZING PSYCHEDELICS California, . Oregon, Colorado
Bridget Sweeney moved from New York to Northern Ireland and shares the cultural differences she saw. Since being here, I've noticed myself walking a lot more, too, and I'm much more active here. I think you can attribute some of that to the active lifestyle, but also to the publicly-funded healthcare system in Northern Ireland. I don't like the coffee they have here in Northern Ireland as much. But overall, I'm happier here and I just feel as if I live a very content, and full life in Northern Ireland.
Persons: Bridget Sweeney, I've, Northern Ireland I've, it's, Alyshia Organizations: Service, Alyshia Hull Locations: New York, Northern Ireland, Ireland, Wall, Silicon, Upstate New York, Binghamton, America, ahull@insider.com
That's where a number of early-stage drug delivery companies come in — and most are flying under investors' radar. Drug delivery tends to be a "roll-up sector," explained Edward Nash, an analyst at Canaccord Genuity. Nash recently looked at four companies operating in drug delivery: Rani Therapeutics , Biora Therapeutics , Avalyn Pharma and Elektrofi. At the moment, the most effective GLP-1 medications for weight loss are delivered via a subcutaneous injection. The verstility of the Rani pill also is encouraging, according to Harrison, since it could be used with a wide range of drugs.
Persons: that's, Edward Nash, Nash, Rani, FactSet, Talat Imran, Eli Lilly, Evercore, Lilly, Genuity's Nash, Julian Harrison, Rani's, Harrison, Cantor Fitzgerald, Olivia Brayer, Imran, We're Organizations: Big Pharma, Therapeutics, Biora Therapeutics, Avalyn Pharma, CNBC, Novo Nordisk, Novo, European Union, Food and Drug Administration, Celltrion Locations:
'Barbie Botox' goes viral but doctors inject caution
  + stars: | 2023-09-01 | by ( Leroy Leo | ) www.reuters.com   time to read: +4 min
But since the "Barbie" movie released in July, there has been an uptick in demand for use as a cosmetic procedure. Meanwhile, Revance and Evolus Inc (EOLS.O), which make similar toxins under the brand Daxxify and Jeuveau, respectively, told Reuters that though "Barbie Botox" has picked up in recent months, they do not see the trend significantly boosting sales. However, the doctors said they were concerned about a rise in use among younger women - and six doctors warned that procedures by underqualified staff at some medispas raised the risk of complications. Doctors also stressed the risk with administration by people who may not be properly qualified, especially at medispas where there is little oversight. "The science isn't quite there yet, in order to support the clinical profile of it," said Evolus CEO David Moatazedi.
Persons: Margot Robbie, BarbieBotox, that's, Barbie, Dustin Sjuts, Scot Glasberg, Revance, Shilpi Kheterpal, Kheterpal, Doctors, Melissa Levoska, David Moatazedi, Leroy Leo, Sriraj Organizations: Therapeutics, Reuters, Plastic Surgery Foundation, U.S . Food, Drug Administration, Evolus Inc, AbbVie Inc, Cleveland Clinic, Icahn School of Medicine, Thomson Locations: New York, U.S, medispas, Mount Sinai, Bengaluru
Apps such as Somryst — known as prescription digital therapeutics — aim to raise the bar for personal healthcare delivered via smartphone. Digital therapeutics show promise for treating IBS and insomniaFunding for digital therapeutics surged by 133% between 2020 and 2021, and the sector's global value is estimated to grow from roughly $7 billion to about $28 billion from now to 2030, Fortune Business Insights reported. In fact, many insurance companies want years of data on real-world use before covering digital therapeutics, Insider previously reported. While there are free nonprescription DTxs available from sources such as the Department of Veterans Affairs, those aren't cleared by the FDA, and privately made prescription digital therapeutics often cost hundreds of dollars. "Digital therapeutics are meant to increase access to care.
Persons: Charlotte Jee, Jee, Corey McCann, John Torous, Beth Israel, they're, Torous, They're, AspyreRx, Mark Berman, hadn't Organizations: Healthcare, Morning, MIT Technology, National Health Service, Food and Drug Administration, Pear Therapeutics, Harvard Medical, Beth Israel Deaconess Medical, Fortune Business, FDA, Better Therapeutics, Disease Control, Department of Health, Human Services, of Health, Department of Veterans Affairs, Aetna
They’re almost enough to make you forget the pleasures of being a little bit bad. We asked 16 writers — most of them respectable adults — about the irresponsible, immoral, indulgent things they do. Years later, we bumped into each other in public, resulting in a humiliating exposition that left everyone questioning my sanity. Can’t stop won’t stop ShopliftingWhenever I’m at the airport, I like to do a little shopping at the Free Store. Yes yes yes.
Persons: , it’s, I’ve, Kennedy, Dan Cathy, Burger King, Jack, they’re, Chick, I’m, , Tell, Wranchers, pant, Henry Hill, Bob Hughes, — let’s, Kelly I, It’s, Saint Augustine, , It’s icky, Jamieson Webster, Rinee Shah Organizations: Harvard, New York Times Locations: British, New York, , YOLO, San Francisco
Now, several space startups see an opportunity to satisfy in-space manufacturing demand using compact space factories. One company is Varda Space Industries in Southern California. Varda Space Industries' first pharmaceutical manufacturing satellite and reentry vehicle attached to a Rocket Lab Photon bus. Years of research have shown that protein crystals grown in space are much higher quality than those grown on Earth. Across the Atlantic in Cardiff, Wales, Space Forge is working on designing its own in-space factory to manufacture next-generation semiconductors.
Persons: Ilan Rozenkopf, Joe Biden, Varda, Asparouhov, we've, Andrew Parlock Organizations: pharma, McKinsey . Space, NASA, ISS, Varda Space Industries, Pfizer, Space Locations: vacuumless, Southern California, U.S, Cardiff , Wales, Space Forge's
In the latest Equity Talk, she shares how she's overcoming biases in the VC and biotech fields. Verge Genomics works with data derived from brains and spinal cords donated by people after they die. That's really been helpful because they don't necessarily see the same kind of questions. But I think part of that is just showing them that there can be a new way of doing things. I think that's an area where naivete can be a benefit, when you have big technological hurdles to overcome.
Persons: Alice Zhang, Zhang, it's, It's, That's, I've, we're, I'm, who's, There's, Alice, aren't, they're, that's unarguable, Organizations: Genomics, Morning, Verge Genomics, Eff, pharma, Tech
A blogger turned wellness influencer and CEO Olivia Amitrano started her business with only $200. She said the best way to grow a blog is to use captivating titles, listicles, and specific solutions. Her supplement business, Organic Olivia, now brings in about $14 million in revenue every year. I grew up with health problems that I always thought were connected, including skin and gut issues and some anxiety. I also have my own supplement line that brought in $14 million in revenue in 2020, my highest-grossing year yet.
Persons: Olivia Amitrano, Olivia, I'd, influencers, I've, we've Organizations: Service, Fordham University, Trader, ArborVitae Locations: Wall, Silicon, New York City, Herbalism, Brooklyn
A tiny-home village in North Carolina is being built for people recovering from mental illness. The village will offer those that move into these homes — all of whom struggle with severe mental illnesses — with access to affordable housing, mental health services, and counseling. Mental health and housing go hand-in-hand, according to various studies. A blueprint for future affordable housing developmentsUltimately, Money-Garman hopes the program goes to show that building affordable housing for those in the most need is possible. "Affordable housing is not going to happen unless we all step in and be ready to donate our time or talent or treasure, or all three," she said.
Persons: Penny Lane, Thava Mahadevan, Mahadevan, Garman Organizations: Service, National Alliance, Mental, University of North, XDS, Inc, UNC's Center, Excellent, Health, Spectrum, Residents, Garman Locations: North Carolina, Wall, Silicon, Penny, Pittsboro , North Carolina, Chapel Hill, University of North Carolina, Pittsboro
One of Google's AI units is using generative AI to develop at least 21 different tools for life advice, planning and tutoring, The New York Times reported Wednesday. Google's DeepMind has become the "nimble, fast-paced" standard-bearer for the company's AI efforts, as CNBC previously reported, and is behind the development of the tools, the Times reported. Google has reportedly contracted with Scale AI, the $7.3 billion startup focused on training and validating AI software, to test the tools. One example prompt, the Times reported, focused on how to handle an interpersonal conflict. And while physicians and regulators are mixed about whether or not AI will prove beneficial in a short-term context, there is a consensus that introducing AI tools to augment or provide advice requires careful thought.
Persons: Sundar Pichai, Google's DeepMind, Bard chatbot, Tessa chatbot Organizations: Inc, Google, O, New York Times, CNBC, Times, The New York Times Locations: Mountain View , California, The
Analyst Maxwell Skor upgraded the biotech stock to overweight from equal weight and raised his price target by $24 to $34. "We see a viable market opportunity with ondemand and short-term prophylactic treatment." The market is split between on-demand treatment and a growing prophylactic segment, according to the note. Skor thinks deucrictibant has a superior safety profile across early clinical trials to the currently dominant therapeutic for the disorder, Orladeyo. He noted, however, that the FDA's clinical hold on prophylactic treatment remains a "key overhang" and that management is expected to submit nonclinical data by 2023.
Persons: Morgan Stanley, Maxwell Skor, angioedema, Skor, Deucrictibant, deucrictibant, HAE, , Michael Bloom Organizations: FDA, deucrictibant
Wegovy prescriptions were up 300% at their peak, according to data from Barclays, before supply issues began to hamper sales. A COMPELLING CASEAnalysts said the data made a compelling case for long-term health benefits of the drug. Analysts were divided on whether Medicare could potentially cover Wegovy as a cardiovascular treatment without a new law passing. Three doctors specializing in obesity treatment, including a cardiologist, were not sure whether such an indication would allow for Medicare coverage. Companies that provide healthcare insurance have begun pulling back on coverage of weight loss drugs because of the high cost of the medicines.
Persons: Read, Eli Lilly, Stacie Dusetzina, Wegovy, Eli Lilly's Mounjaro, Evan Seigerman, Eugene Yang, Morningstar, Damien Conover, Tom Carper, Eli Lilly's, Dusetzina, Patrick Wingrove, Elissa Welle, Ahmed Aboulenein, Caroline Humer Organizations: Novo Nordisk, U.S, Vanderbilt University, Medicare, Barclays, University of Washington Medicine, Companies, Democratic, Novo, Reuters, Democrat, Republican, Thomson Locations: New York, Danish, Washington
In earlier cultural epochs, many people derived their self-worth from their relationship with God, or from their ability to be a winner in the commercial marketplace. But in a therapeutic culture people’s sense of self-worth depends on their subjective feelings about themselves. Do I feel good about myself? From the start, many writers noticed that this ethos often turned people into fragile narcissists. It pushed them in on themselves, made them self-absorbed, craving public affirmation so they could feel good about themselves.
Persons: Philip Rieff, Christopher Lasch, Tom Wolfe, Lasch, ” Lasch,
New York CNN —Barbara Lakin sits on a bus in New York City, her fingers busy sewing blue thread into a tiny dress. On the seat beside her, six disheveled Barbie dolls stick out of her backpack. Cory CurtinUsing old Barbies she buys or donated dolls, Lakin, a New Yorker living in the East Village, restores the toys as gifts for the children. In March, the organization also opened the Little Shop of Kindness, where the migrants can shop for free and young migrant girls can receive the Barbies. This way, she can donate matching Barbie dolls and shirts to father-and-daughter duos who come to the store.
Persons: Barbara Lakin, Barbie, ” Lakin, Lakin, Cory Curtin, , , Greg Abbott, Human Services Anne Williams, Eric Adams ’, Alejandro Mayorkas, Williams, Isom, Ilze Thielmann, Thielmann, Ilze, , we’re, Barbara Lakin Lakin, Barbies Organizations: New, New York CNN, CNN, TLC, New York’s Port Authority Bus, Texas Gov, Health, Human Services, Homeland, Migrants, WCBS, Port Authority, Kindness Locations: New York, New York City, Central, South America, New Yorker, East, New York’s, Washington and New York, Midtown Manhattan, Long Island City, Bryant, England, Latina
The roof of a Pfizer facility shows heavy damage after a tornado passed the area in Rocky Mount, North Carolina, U.S. July 19, 2023. The company's Rocky Mount plant is one of the world's largest factories for sterile injectable medicines. The tornado that struck the site completely destroyed the warehouse, but production facilities there did not suffer major damage, Pfizer had said earlier. Earlier this week, CEO Albert Bourla said the company is still assessing how long it will take to bring the plant back on line. Reporting by Sriparna Roy and Bhanvi Satija in Bengaluru; Editing by Pooja DesaiOur Standards: The Thomson Reuters Trust Principles.
Persons: Albert Bourla, Sriparna Roy, Bhanvi, Pooja Desai Organizations: Pfizer, ABC, WTVD, REUTERS, Pfizer Inc, Thomson Locations: Rocky Mount, North Carolina, U.S, Bengaluru
Berry suspended for second time for anti-doping violation
  + stars: | 2023-08-02 | by ( ) www.reuters.com   time to read: +1 min
Aug 2 (Reuters) - American hammer thrower Gwendolyn Berry, a two-time Olympian and a Pan Am Games gold medallist, has been given a 16-month suspension after testing positive for a banned substance, the United States Anti-Doping Agency (USADA) said on Wednesday. It is the second doping ban within a 10-year period for Berry, who was a member of the 2016 and 2020 U.S. Olympic teams. Berry’s violation resulted from her use of a topical medication containing the diuretic and masking agent spironolactone for which she had a prescription. However, Berry failed to obtain a Therapeutic Use Exemption for the medication. Berry's 16-month ban was backdated to April 28, the date her provisional suspension was imposed, ruling her out of this month's world athletics championships in Budapest.
Persons: Gwendolyn Berry, Berry, Steve Keating, Clare Fallon Organizations: Pan Am Games, United, United States Anti, Doping Agency, Olympic, Pan Am, U.S ., Thomson Locations: American, United States, Budapest, Lima, Toronto
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