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The hotly anticipated results are in from a landmark pair of major clinical trials of a long-acting, injectable HIV-prevention drug that only requires dosing every six months. The pharma giant has already secured approval for the injectable drug in treating highly drug-resistant HIV. Given the clear statistical superiority of lenacapavir over Truvada, the trial’s blinded phase will now be ended several months early. When taken as prescribed, Truvada is over 99% effective at preventing HIV; Descovy is comparably effective. This chorus is sure to get louder now that lenacapavir is officially highly effective at protecting gay and bisexual men and trans people as well.
Persons: lenacapavir, , Jared Baeten, , ” Jen Kates, ” Gilead, Gilead, Truvada, ViiV Healthcare’s, Amy Killelea, Jirair Ratevosian, Hansel Tookes, ” Tookes, Dr, Boghuma, “ lenacapavir, Tim Horn Organizations: Gilead Sciences, pharma, NBC, Food and Drug Administration, Disease Control, PrEP, Yale School of Nursing, University of Miami Miller School of Medicine, NBC News, Southern, Affordable, CDC, Emory University Locations: Gilead, United States, , U.S, Australia, United Kingdom, Arlington , Virginia, America, South Africa, Thailand, Truvada, Atlanta, Saharan Africa
Gilead 's twice-yearly shot reduced HIV infections by 96% in a second large study, the company said Thursday. The positive phase three trial data on lenacapavir sets the stage for likely approval by the U.S. Food and Drug Administration for HIV prevention. The company said 99.9% of participants who received lenacapavir did not acquire HIV, with two cases among 2,180 people. Gilead in June also said lenacapavir was 100% effective at preventing HIV in another late-stage trial with cisgender women. The trial results should lead to an FDA approval and launch in the market by 2025, Yee said.
Persons: Gilead, Daniel O'Day, lenacapavir, Michael Yee, Yee Organizations: U.S . Food, Drug Administration, PrEP, Centers for Disease Control, Jefferies, CNBC, YouTube Locations: Gilead
New York Police Department Commissioner Edward Caban speaks during the first quarter crime briefing press conference Wednesday, April 3, 2024, in Manhattan, New York City. NYPD Commissioner Edward Caban resigned Thursday from his post helming the country's largest police department amid a federal investigation into its nightclub enforcement, according to a memo obtained by News 4. I have therefore decided it is in the best interest of the Department that I resign as Commissioner." Caban, who was appointed to the job in July 2023, became the first Latino to serve as commissioner of the NYPD in its 179-year history. Several sources tell NBC New York federal investigators want to know if James Caban profited from his ties to his powerful brother and the NYPD.
Persons: Edward Caban, Caban, Eric Adams, Adams, Tom Donlon, James Caban, Caban's, Russell Capone, Rebekah Donaleski Organizations: New York Police, NYPD, News, NYPD –, Department, U.S, Attorney's, Southern, of, IRS, NBC New, New York City Police Department, Cooley Locations: Manhattan , New York City, of New York, NBC New York, Midtown, Queens
Seoul, South Korea CNN —South Korea has for decades been known as the world’s largest “baby exporter” – sending hundreds of thousands of children overseas after the country was ravaged by war and many mothers left destitute. Searching for their rootsMore than 200,000 South Korean children have been adopted overseas since the 1950s following World War II and the Korean War, according to authorities. While adoptions continue today, the trend has been declining since the 2010s after South Korea amended its adoption laws in an effort to address systematic issues and reduce the number of children adopted overseas. “It’s truly terrifying to hear how systemic these issues were, but I wouldn’t say it’s necessarily surprising,” said Susanné Seong-eun Bergsten, who was adopted from South Korea and grew up in Sweden. “There is still much about Korean adoption that has not been formally acknowledged.”
Persons: , adoptees, , Susanné Seong, Mark Zastrow, Bergsten Organizations: South Korea CNN, Commission, CNN, Korean Locations: Seoul, South Korea, Korea, Korean, Daegu, Sejong, United States, Australia, Norway, Denmark, Europe, It’s, Sweden, adoptees
CEO of Ford's highly profitable Pro business to retire
  + stars: | 2024-09-12 | by ( Michael Wayland | ) www.cnbc.com   time to read: +1 min
Ted Cannis, chief executive officer of Ford Pro, speaks during an interview in New York, on Thursday, July 28, 2022. DETROIT — The head of Ford Motor 's highly profitable "Pro" commercial and fleet business will retire at the end of this month, the company said Thursday. Ford Pro has been a profit-driver for the automaker. It has raked in about $18.7 billion in adjusted earnings and $184.5 billion in revenue since 2021, assisting in offsetting losses of its electric vehicles business. Such results led Wall Street to praise the business, as analysts have called it a "hidden gem" and Ford's "Ferrari ," referring to the highly profitable Italian sports car manufacturer.
Persons: Ted Cannis, DETROIT —, Andrew Frick, Ford, Jim Farley, Wall, Ferrari Organizations: Ford Pro, DETROIT, Ford Motor Locations: New York
Making a creature come to life in a video game is a collaborative process, where she interprets the directions to bring characters to life. Interactive media contract negotiations between SAG-AFTRA and video game studios have been ongoing since 2022 and have stalled due to disagreements over AI protections. Tensions in the ongoing video game strikes arose over how AI can be used for "digital replicas" and whether actors can be compensated for them. If you've played video games at all, that is almost never the case," Norris said. Related storiesThese negotiations take place amid a slowdown in the $200 billion video game industry.
Persons: , Andi Norris, Norris, AFTRA, you've, Audrey Cooling, Linsay Rousseau, Rousseau, Connor Fogarty, Fogarty, Sarah Elmaleh, Sean Rohani, Rohani, Elmaleh Organizations: Service, Business, Interactive, SAG, Hollywood, Writers Guild of America, Activision, Union, of Locations: Los Angeles, Ethovox
Read previewVilla Vie Residences' highly anticipated residential around-the-world cruise has been delayed yet again from its original May target date, it told waiting customers on Monday. Villa Vie acquired Odyssey, formerly the Fred Olsen Cruise Lines' Braemar vessel, in December. Villa Vie Odyssey is currently docked in Belfast, Ireland. Angela and Stephen TheriacSince May, more than 100 Villa Vie buyers have stayed in the UK in anticipation of the ship's departure. Since the initial delay, Petterson told BI that Villa Vie had paid almost $2 million for its buyers' hotels.
Persons: , Fred Olsen Cruise, Villa Vie, Lanette Canen Mikael Petterson, Vie, Petterson, Villa, Angela, Stephen Theriac, they've Organizations: Service, Residences, Business, Fred Olsen Cruise Lines, Vie, YouTube Locations: Belfast , Northern Ireland, Braemar, Belfast, Ireland
“I think President Trump is saying exactly what I have been saying, and that is we need assurances on election security and to fund the government,” Johnson told CNN’s Jake Tapper on “The Lead” Tuesday. “I talked with the president a lot, President Trump, and that has always been my advice that we run this race on policy, on record, not rhetoric, on policy, not personality,” he said. On Vice President Kamala Harris, Johnson said, “She has a big, a big task ahead of her tonight. To this day, Joe Biden and Kamala Harris have not said the names of those service members. In fact, Joe Biden said on the debate stage in June that we hadn’t lost any service members on his watch.
Persons: Mike Johnson, Donald Trump, Republicans “ don’t, , , Trump, ” Johnson, CNN’s Jake Tapper, Trump’s, Johnson, Kamala Harris, Joe Biden, Michael McCaul, Harris, Tapper, Kamala Harris’s, That’s Organizations: Washington CNN —, Republicans, Security, GOP, SAVE, noncitizens, House Foreign, Republican Locations: Kabul, Afghanistan, Texas
Bali considering a ban on new hotels amid overtourism struggles
  + stars: | 2024-09-10 | by ( ) edition.cnn.com   time to read: +2 min
The moratorium is part of the government’s bid to reform tourism on Bali, one of Indonesia’s main attractions, to try to boost quality and jobs while preserving the island’s indigenous culture. The governor’s office and Indonesia’s tourism ministry did not immediately respond to requests for comment on Monday. Luhut has previously said about 200,000 foreigners now live in Bali, contributing to problems such as crime, over-development and competition for jobs. Foreign arrivals in Bali have surged since it re-opened for tourism after the COVID-19 pandemic. There were 541 hotels in Bali last year, the figures show, up from 507 in 2019.
Persons: Hermin, Sang, Mahendra Jaya, Luhut Pandjaitan, Luhut Organizations: Reuters —, Coordinating Ministry of Maritime and Investment Affairs, Reuters Locations: Reuters — Indonesia, Bali, Indonesia
“The second reason that breast density is important is because having dense breast tissue raises a woman’s level of risk of developing breast cancer,” Feigin said. Breast cancer survivor JoAnn Pushkin, 64, has advocated for more than a decade that there be a national requirement for women to be notified of their breast density. Now I have lymphedema, and all because it was detected at that later stage,” said Pushkin, who has testified before the FDA about breast density and co-created the website DenseBreast-info.org, which features resources on breast density. The new FDA changes require facilities to provide patients with information about their breast density and include specific language in the mammogram result letter to explain how breast density can influence the accuracy of a mammogram. A study published in 2022 found that the breast cancer death rate dropped by 43% within three decades, from 1989 to 2020, translating to 460,000 fewer breast cancer deaths during that time.
Persons: Kimberly Feigin, ” Feigin, JoAnn Pushkin, Pushkin, she’d, , ” Pushkin, , Pushkin’s mammogram, , wasn’t, Wendie Berg, Berg, ” Berg, it’s, Molly Guthrie, Susan G, Komen, ” Guthrie, we’ve, Dr, Sanjay Gupta Organizations: CNN, US Food, Breast Imaging Service, Assurance, Memorial Sloan Kettering Cancer Center, District of Columbia, FDA, University of Pittsburgh School of Medicine, Magee, Womens Hospital of UPMC, American Cancer Society, CNN Health Locations: United States
LONDON — Britain's competition watchdog on Friday issued a statement of objections over Google's ad tech practices, which the regulator provisionally found are impacting competition in the U.K. In a statement, the Competition and Markets Authority alleged that the U.S. internet search titan "has harmed competition by using its dominance in online display advertising to favour its own ad tech services." The CMA further noted that Google disadvantages ad technology competitors, preventing them from competing on a "level playing field." "Many businesses are able to keep their digital content free or cheaper by using online advertising to generate revenue. The core of this case rests on flawed interpretations of the ad tech sector."
Persons: Juliette Enser, , Enser, Dan Taylor, Taylor Organizations: Markets Authority, CMA, Google Locations: U.S
New York CNN —Chipotle is already getting into the Halloween spirit. The fast-casual chain announced a costume collection with Spirit Halloween Wednesday, the seasonal Halloween costume store that pops up every year in abandoned storefronts. Two years ago, it posted a fake “Chipotle Fork” bodysuit with the caption “Found ur costume.” Then last year, another fake “Chipotle Napkin” costume showed up on its Instagram. The Chipotle Fork costume, for example, is just a plain black, polyester bodysuit. “Our popular Halloween tradition, Boorito, began with a burrito-themed costume contest and now we’re taking it to the next level with the launch of our first-ever costume collection in collaboration with Spirit Halloween,” said Chris Brandt, chief brand officer at Chipotle in a statement.
Persons: New York CNN — Chipotle, Chipotle, , Chris Brandt, Brian Niccol, Taco, Scott Boatwright Organizations: New, New York CNN, Burt’s, Retailers, Taco Bell Locations: New York, Canada, Chicago, Denver, Egg Harbor Township, N.J, Los Angeles
Jessica Gow | Afp | Getty ImagesRussia's ongoing war in Ukraine has resulted in a profound shift in the way defense stocks are viewed by mission-driven fund managers, according to two European defense giants. Defense stocks have typically been excluded from portfolios based on environmental, social and governance (ESG) factors due to ethical concerns over their association with warfare. Nonetheless, the inclusion of defense stocks in sustainably-minded portfolios remains controversial. It's really important that we see the role that defense companies play in protecting a free society. It's really important that we see the role that defense companies play in protecting a free society," he said.
Persons: Micael Johansson, Jessica Gow, Johansson, CNBC's Silvia Amaro, It's, Brad Greve, BAE Systems Johansson, hasn't, Ida Kassa Johannesen, Johannesen, Justin Tallis, Saab's Johansson, ESG, John Keeble, Greve Organizations: Saab, Afp, Getty, BAE Systems, Ukraine —, Saxo Bank, CNBC, Democratic, U.S, Republican, Democrats, Malloy Aeronautics, British Aerospace BAE Systems, Farnborough, Exhibition, Conference Centre Locations: Stockholm, Ukraine, Africa, Democratic Republic, Congo, Palestine, London, Farnborough, England
The Education Department is assuring schools and students that its financial aid process is under control, after a botched overhaul over the past year that some colleges say has dented incoming classes. Education Secretary Miguel Cardona has vowed that the FAFSA process is being improved after recent missteps. I want to close up [the] Department of Education, move education back to the states. In May, Cardona announced a “full-scale review” of the Federal Student Aid office that oversees FAFSA and promised “transformational changes” at the division. I’ve taken a college and career readiness class from my high school, but it all sounded really confusing,” she said.
Persons: Miguel Cardona, he’s, We’ve, miguel cardona, “ We’ve, ” Cardona, , Peter G ., NAICU, couldn’t, ” Mark Becker, Donald Trump, disburses Pell, ” Trump, Elon, Cardona, “ We’re, they’re, ” “, falloff, Beth Maglione, Hanalise Yarbrough, Kristi Childs, Kristi Childs Kristi Childs, Childs, Mason Yarbrough, , ” Childs, Hanalise, John Jay, she’s “, I’ve, who’s “ Organizations: Department, Education, Federal Student Aid, NBC News, National Association of Independent Colleges, Universities, Education Department, Association of Public, Grant Universities, Department of Education, Republican, Federal, Aid, College, Network, National Association of Student Financial, Madison, Northwest Mississippi Community College, John, John Jay College of Criminal Locations: U.S, DeSoto County , Mississippi, New York City
AdvertisementThat is, until this spring, when Canen and Bodin, both 54, uprooted their lives in Maui, Hawaii, to move onto a new residential cruise ship called Villa Vie Odyssey. AdvertisementThe couple sold their business in MauiBodin told BI that before Villa Vie, the couple had never really considered leaving Maui. "We went pretty much every day for two weeks and spent all day there until they kicked us off," Canen told BI. AdvertisementBefore committing to Odyssey, Canen and Bodin looked into Storylines, which plans to construct its own residential cruise ship, MV Narrative. AdvertisementAre you sailing on a residential cruise ship like Villa Vie or have a tip?
Persons: , Lanette Canen, Johan Bodin, Canen, Bodin —, we'd, Bodin, Mikael Petterson, Fred Olsen Cruise, Lanette, Villa Vie's, Villa, Maui Bodin, they've, Petterson, Villa Vie, We're, Angela, Stephen Theriac Canen, they'd, Kendra Holmes, they're Organizations: Service, Business, Villa, Residences, Fred Olsen Cruise Lines, South Pacific, YouTube, Sea Cruises, Cruises, Victoria Cruises Locations: Maui, Hawaii, Europe, Asia, Australia, South, North America, Africa, Belfast, Ireland, Braemar, Maui —, Italy, Croatia, Slovenia, Sweden, Canary, Norwegian, Villa Vie, Canen, Petterson
While locking their credit won't solve all cybersecurity issues related to stolen Social Security numbers, it's one extra layer of protection parents can implement. Parents can take these steps proactively even if there's nothing to suggest a minor's credit has been compromised such as unexpected credit card solicitations or bills received in the minor's name. It can take some time and effort to lock a child's credit, but the outlay is minimal compared with what can be a lengthy and emotional credit restoration process. Locking a child's credit won't protect against all of these, but it's a solid step in the right direction, financial professionals said. To check to see if their child has a credit report, parents can mail a letter with their request to each of the credit bureaus.
Persons: , Kim Cole, Loretta Roney, It's, Cole, Bruce McClary, McClary Organizations: Social, Social Security, Navicore Solutions, InCharge, Federal Trade Commission, Administration, Foundation, Credit Counseling
Janet Mills launched the commission a month after the Oct. 25 shooting killed 18 people at a bowling alley and a bar. Wathen said the commission's investigatory process was slowed by Army bureaucracy in obtaining information but that the military remained cooperative. But the sergeant said law enforcement was stymied at the time because Card refused to answer his door. There were also communication gaps between the Army and the civilian hospital, the report found, which can be improved in future cases. The military in its report denied that any brain-related injury was linked to his military service.
Persons: Robert Card, Janet Mills, Daniel Wathen, Wathen, Robert F, Card's, Mills, ideations, Ben Gideon, Gideon, Cara Lamb Organizations: Army, U.S, Sheriff's, Card's Army Reserve, Card, Keller Army Community Hospital, Maine Gov, Maine State Police, Department of Defense Locations: Lewiston , Maine, West Point , New York, West Point, Maine
Some of the violence pitted student activists against pro-government student and youth groups and police, and many of those who died were among the student activists. However, Hasina’s statement underlined that police officers, members of her Awami League political party, bystanders and others also were victims of what she described as “terrorist aggression.” She previously has blamed opposition parties for stoking the unrest. Hasina’s statement came as the country’s interim government on Tuesday canceled a public holiday that she had declared for Thursday to mark the death of her father, Bangladesh’s independence leader Sheikh Mujibur Rahman. The cancellation came at the request of at least seven political parties, including the main previous opposition group, the Bangladesh Nationalist Party. An interim government is now running the country, with Muhammad Yunus, a Nobel peace laureate, sworn in as interim leader.
Persons: Bangladesh —, Sheikh Hasina, Hasina, Sajeeb Wazed Joy, Hasina’s, Sheikh Mujibur Rahman, S.M, Amir Hamza, Abu Sayeed, Rajesh Chowdhury, Hamza, Sayeed, Asaduzzaman Khan, Obaidul Quader, Rajib, Anisul Huq, Salman F, Rahman, Mainul Hasan, Muhammad Yunus Organizations: Awami League, Bangladesh Nationalist Party, Home, Awami League party’s, Mohammadpur, Police Locations: DHAKA, Bangladesh, India, Dhaka, Rajib Dhar, U.S
When Yasmine invited her to join the road trip across Turkey, Sema happily accepted. “I knew nothing about them.”And then, when she was introduced to Kenneth, Sema also felt an instant connection to him. Kenneth Wayne HarlOver the next few days, as Kenneth, Sema and their friends Jason and Yasmin drove across Turkey, Kenneth and Sema grew closer. Kenneth and Sema spent the rest of the ferry crossing basking in the glow of each other’s affection. “In Urfa, the four of us attended a dinner and traditional dance performance in the evening,” recalls Kenneth.
Persons: Kenneth Harl, Sema, , Kenneth, ” Kenneth, Jason, Yasmine, , Nemrut, She’d, – she’d, hadn’t, ” Sema, , Kenneth Wayne Harl, Yasmin, Nemrut Dağ, Kenneth wasn’t, Jason – who’d, , , ’ ”, ” Jason, – you’re, it’d, it’s, Kenneth Wayne Harl Kenneth, They’d, Ken, who’d, you’re, ” “, hasn’t, “ I’m, he’d, We’ve, I’m, He’s Organizations: CNN, CNN Travel, Tulane University, Tulane, UNESCO, Heritage, Sema, Skype, American Research Institute, London, Locations: Malatya, Turkey, New Orleans, Izmit, Jason, Urfa, Harran, Sema, Nemrut, United States, Istanbul, Büyük Ada, , Ankara, Paris, India, France, Hurricane
New York City has also seen a surge in bicycling since the pandemic caused many to avoid mass transit and ride shares. And the funding for the Streets Plan — more than $900 million — has already been allocated to DOT. The city streets were designed to maximize vehicle speed rather than to get as many New Yorkers around as efficiently and safely as possible. While New York City streets have generally gotten safer since the city adopted its 'Vision Zero' plan in 2014 to eliminate traffic deaths and serious injuries in 2014, progress hasn't been consistent. Advertisement"What New York City can learn is that when you commit to comprehensive bike infrastructure, it works," Elizabeth Adams said.
Persons: Adams isn't, Adams, doesn't, Elizabeth Adams, Kathy Hochul, it's, they're Organizations: Service, Business, Department of Transportation, DOT, Transportation, New York Gov, New Locations: Paris, New York City, New York, London, Manhattan, Cities, Tokyo, York City
Three officials from different countries said the measured response comes as they are mindful of what happened after Maduro’s 2018 reelection. Then, the vote was quickly condemned as a sham and led to the most severe sanctions yet on the OPEC nation. In Washington, which under Republican President Donald Trump blocked Venezuela’s critical oil exports, there seems little appetite for more severe sanctions. The European Union last week said there was not enough evidence to support Maduro’s victory as announced by the CNE. Countries including China, Russia, Nicaragua and Cuba have recognized Maduro’s victory and offered him support.
Persons: Nicolás Maduro, Edmundo González, Jose Manuel Albares, Maduro’s, Donald Trump, Biden, Maria Corina Machado, Gonzalez, , Vedant Patel, Maduro, Elvis Amoroso, Kamala Harris, , , Machado Organizations: Electoral Council, Maduro, United Nations, EU, Republican, Democratic U.S, Venezuela’s, U.S ., . State Department, . Washington, U.S, U.S . Treasury Department, State Department, Reuters, American States, Electoral, International, European Union, CNE, NBC Locations: U.S, Brazil, Venezuela, Spanish, Spain, OPEC, Maduro, Washington, ., reneging, Elvis Amoroso ., Mexico, Colombia, Canada, Panama, China, Russia, Nicaragua, Cuba
Starbucks is parting ways with its CEO and bringing in the head of Chipotle to lead the coffeeshop chain, as it seeks to revive flagging sales and appease outside investors. Starbucks announced Tuesday that Brian Niccol, who has led the Mexican-style chain since 2018, will take over the coffee giant starting next month. Laxman Narasimhan, who'd been with Starbucks for less than two years, is exiting the company. But in its release announcing the change, Starbucks said Niccol had "transformed" Chipotle. Starbucks CFO Rachel Ruggeri will step in as interim chief executive until Sept. 9, when Niccol officially takes over the top job.
Persons: Brian Niccol, Laxman Narasimhan, who'd, who’d, Chipotle, Niccol, Rachel Ruggeri, Scott Boatwright, Jack Hartung Organizations: Starbucks Locations: Mexican, U.S, China
Starbucks unveiled an abrupt leadership change on Tuesday: Brian Niccol, a high-profile name in the restaurant industry, is taking the reins, after months of weak sales at the coffee giant and a falling stock price. Mr. Niccol will step in as chief executive next month, replacing Laxman Narasimhan, whose relatively brief stint in the top job at Starbucks began in March last year. The company’s chief financial officer, Rachel Ruggeri, will serve as interim chief executive until Mr. Niccol officially joins the company on Sept. 9. Mr. Niccol is coming off of six years at the helm of Chipotle Mexican Grill — a period that saw the fast-casual burrito chain nearly double its sales. The company’s stock price has increased about 800 percent since he took over in early 2018.
Persons: Brian Niccol, Niccol, Laxman Narasimhan, Rachel Ruggeri, Chipotle Organizations: Starbucks
Chipotle stock fell as much as 10% in premarket trading Tuesday as the company announced CEO Brian Niccol would be leaving his role on Aug. 31 to become CEO of Starbucks . Niccol began as Chipotle CEO in March 2018. Chipotle stock has risen more than 700% since since he took over. Niccol helped lead Chipotle through a foodborne illness scandal and oversaw the chain of restaurants during the pandemic. Before taking over at Chipotle, Niccol was the CEO at Yum Brands' Taco Bell.
Persons: Brian Niccol, Niccol, Scott Boatwright, He's, Jack Hartung, Brian, Mellody Hobson, Chipotle, — CNBC's Amelia Lucas Organizations: Starbucks, Yum Brands, Bell Locations: Chipotle
vehicles, their hoods adorned with Bangladesh’s national flag according to state protocol, idled late one recent evening in a ground-floor parking lot at the University of Dhaka. Just a week before, they were hounded leaders of a youth-driven popular uprising against the country’s seemingly unbreakable prime minister. Now, after her astonishing ouster, the two are cabinet ministers in the country’s interim government. Inside the parking lot, young women and men milled around these unlikeliest of government officials, asking questions and posing for selfies. On a pillar at the entrance, spray-painted graffiti declared the moment: “Revolution is not a dinner party.”Outside, the streets of this country of 170 million people are run by students.
Persons: autocrat, Sheikh Hasina Organizations: University of Dhaka, selfies
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