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CNN —Results are in from the highly anticipated clinical trial on the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay or MIND diet — a diet designed specifically to boost the brain — and they are less stellar than anticipated. Actually, the MIND diet did improve the brains of those who followed it for three years. Past studies have shown both the MIND diet and the Mediterranean diet significantly reduced the risk of cognitive decline and Alzheimer’s disease. The MIND diet also assimilates elements of the Dietary Approaches to Stop Hypertension (or DASH) diet. The DASH diet has been shown to reduce blood pressure and is the American Heart Association’s top diet.
Persons: , Lisa Barnes, Barnes, Walter Willett, Harvard T.H, Willett, “ It’s, David Katz, ” Katz, romaine, ” Willett, , Katz Organizations: CNN, Disease Research, Rush University Medical Center, Harvard, of Public Health, Harvard Medical School, True Health Initiative, Rush University, New, of Medicine, Blue Locations: Chicago, Chan, Amsterdam, American, Swiss chard
How America fell out of love with ice cream
  + stars: | 2023-07-16 | by ( Danielle Wiener-Bronner | ) edition.cnn.com   time to read: +9 min
Ice cream is “the ultimate comfort food.”Drinkers swapped a pint for a scoop, and for ice cream makers, Prohibition was a boon. “In fact they say that the ice cream business is bound to increase in volume from year to year as more people are using ice cream since the coming in of nation-wide prohibition and the going out of the saloon.”The interest in ice cream continued in World War II, buoyed by the government’s use of the frozen dessert to help boost morale. Margaret Bourke-White/The LIFE Picture Collection/Shutterstock“We built pop-up ice cream factories on the front lines, delivered individual ice cream cartons to foxholes and spent more than a million dollars on a floating ice cream barge that patrolled the Pacific delivering ice cream,” Siegel said. Scoops of Falooda ice cream are placed on top Blueberry Lavender ice cream at Pints of Joy in Sunnyvale, California. Today, she teaches aspiring ice cream entrepreneurs how to make ice cream.
Persons: Earl Leaf, Michael Ochs, Baskin Robbins, , Matt Siegel, ” Siegel, Yuengling, , Margaret Bourke, , Siegel, John Robbins, Robbins, Burt Baskin, Robbins ’, ” Robbins, Robbins “, Deepak Chopra, Marianne Williamson, Lucas Fuess, Richard B, Levine, Levine Roberts, Fuess, John Crawford, “ There’s, Circana, Aric Crabb, Talenti, Earl Grey, ” Crawford, Bryan Olin Dozier, Deborah Lee Organizations: New, New York CNN, US Department of Agriculture, Michael Ochs Archives, Food, Anheuser, Busch, Manufacturers, Cream, Baskin, New York Times, Rabobank, MediaNews, East Bay Times Locations: New York, NY, American, USS Maryland, Chicago , Illinois, Circana, Joy, Sunnyvale , California, Van Leeuwen, North Carolina
Researchers hoped to find evidence of a healthy new generation of ospreys when they checked 84 nests of the fish-eating bird in mid-June at Mobjack Bay, an inlet at the southern end of the Chesapeake Bay. It was the lowest reproductive number in more than 50 years of monitoring the local population of the raptor, according to scientists at the College of William & Mary. And they said it represented the latest evidence in a long-term decline in breeding success due to the bay-wide depletion of the bird’s favorite food — Atlantic menhaden. The fish are nutrient-rich, a good source of Omega-3 fatty acids; they consume smaller organisms like plankton and they filter huge quantities of ocean water. But they are also a mainstay of the commercial fishing industry, caught in mass quantities to be processed into bait for crabs and lobsters, and in greater volume for so-called reduction fisheries, in which they are ground up and turned into products including fish oil and fish meal.
Persons: College of William & Mary Organizations: ospreys, College of William &, Eastern Seaboard Locations: Mobjack, Chesapeake
Pfizer makes equity investment in Caribou Biosciences
  + stars: | 2023-07-06 | by ( ) www.reuters.com   time to read: +2 min
July 6 (Reuters) - Pfizer (PFE.N) has invested $25 million to buy a minority stake in Caribou Biosciences (CRBU.O), making it the latest small biotechnology firm to attract the pharmaceutical giant's interest. The news lifted shares of Caribou more than 61% in early trade. Pfizer purchased nearly 4.7 million Caribou shares at $5.33 per share, Caribou said on Thursday, representing a premium of about 30% over Caribou's previous close price. This represents 7.64% of outstanding shares in Caribou, according to Reuters' calculation based on Refinitiv IBES data. It also made a $25 million equity investment in Akero Therapeutics (AKRO.O) last year.
Persons: Caribou, NASH, Jennifer Doudna, Raghav Mahobe, Leroy Leo, Maju Samuel Organizations: Pfizer, Caribou Biosciences, Biohaven Pharmaceutical, Akero Therapeutics, Thomson Locations: Caribou, California, Bengaluru
Wegovy was approved as an obesity treatment in June 2021 , but Ozempic, a Type 2 diabetes treatment, has been used off-label for weight loss. Mounjaro uses GLP-1 and gastric inhibitory polypeptide, or GIP, to help patients lose weight. Eli Lilly's oral drug, orforglipron, has an even better profile . They also could be helpful in assisting patients in maintaining weight loss after they've used the injectable versions, he said. Some have highlighted that oral drugs also may be more manageable for patients who can't handle the idea of giving themselves a once-a-week injection.
Persons: Eli Lilly, we're, Jonathan Wolleben, Wegovy, Lilly's tirzepatide, It's, Mounjaro, Wolleben, Eli Lilly's tirzepatide, Lilly, , Novo, Eli, it's, they've, FactSet, Altimmune's pemvidutide, Morgan Stanley, Mark Purcell, Purcell, Graig Suvannavejh, Suvannavejh, Roth, Dylan Dupuis, Dupuis, Trung Huynh, Goldman Sachs, Chris Shibutani, Shibutani Organizations: Novo Nordisk, JMP Securities, Citizens Company, Nordisk's Ozempic, Food and Drug Administration, Nordisk, Novo, Zealand Pharma, Shandong Suncadia, GSBR, Biosciences, Fujian Shengdi Pharmaceutical, Mizuho Securities, Terns Pharmaceuticals, American Diabetes Association, Viking Therapeutics, Pfizer, Credit Suisse, AstraZeneca, Therapeutics, Medicare, Medicaid, CNBC Pro's Locations: Danish, Shandong, Fujian, Viking
A Culinary Roman Empire’s Next Conquest? Manhattan.
  + stars: | 2023-06-30 | by ( Julia Moskin | ) www.nytimes.com   time to read: +1 min
But in New York, the challenge will be replicating the quality of ingredients that Roscioli is known for, not only in its pastas but also on its plates of exceptionally fresh cheeses like burrata, buffalo mozzarella and buffalo ricotta, and cured meats like mortadella and prosciutto — few of which can be served in the United States. Fresh cheeses made from raw milk can’t be imported at all, though aged cheeses like Pecorino Romano can be. “The winds keep changing,” said Zach Allen, who has overseen food imports at the U.S. locations of Eataly and the fast-growing Florentine sandwich chain All’Antico Vinaio. “The imports used to be so heat-treated and over-cured that they didn’t taste anything like the original,” he said, referring to regulations imposed by the U.S. Department of Agriculture on cured meatsOver decades, Mr. Allen has painstakingly developed relationships and recipes with U.S. producers who make what he needs, like a fatty, fennel-spiked Tuscan salami called sbriciolona for La Favolosa, a top-selling sandwich at the New York locations of All’Antico. “The Rosciolis are at the very beginning of that process.”
Persons: , Zach Allen, Allen, La Organizations: U.S . Department of Agriculture Locations: New York, United States, U.S, Eataly, York, All’Antico
What's more, some showed no signs their weight loss was leveling off, suggesting they could continue to shed pounds. (Both use semaglutide, but Ozempic is marketed as a type 2 diabetes treatment, while Wegovy is primarily for weight loss.) Bank of America's Geoff Meacham said retatrutide "exceeded expectations" for weight loss. "This is important, as while the overall 22.4% weight loss was impressive, looking at men and women separately, weight loss was 21.9% and 28.5%, respectively, with the slope in females not yet plateauing. Schott also described the weight loss as "impressive" and said it will likely compare favorably with Novo's next-generation drug CagriSema, which is expected to show weight loss of more than 25% when it releases its next update.
Persons: Eli Lilly, What's, Lilly, Lilly's, Carter Gould, Gould, orforglipron, Bank of America's Geoff Meacham, retatrutide, Meacham, Chris Schott, Schott, Novo's, Evan David Seigerman, Seigerman, Morgan Stanley, Terence Flynn, — CNBC's Michael Bloom Organizations: American Diabetes Association, Wall, Novo Nordisk, Barclays, Bank of America's, JPMorgan, Lilly, BMO Capital, Indianapolis, ~$ Locations: Novo
More and more people are adding fish into their diets for the heart-healthy omega-3 fatty acids. But it may be time to skip the salmon and tuna, and reach for foods lower on the seafood chain like sardines and clams instead. "So, although they are underutilized, they're really good at delivering those sorts of nutrients." Bivalves, like mussels, are also a "really healthy choice," Golden notes, and they're great sources of zinc and calcium. Here's what Golden recommends adding to your diet to replace foods like red meat and farmed salmon.
Persons: Christopher Golden, they're Organizations: Harvard, of Public Health, CNBC Locations: Chan
A Quick and Easy Skillet Chocolate Chip Cookie
  + stars: | 2023-06-21 | by ( Melissa Clark | ) www.nytimes.com   time to read: +1 min
Both the cookie and the cake would pair delightfully with an iced coffee lightened with Gabriella Lewis’s sweet cream cold foam. Serve it with Eric Kim’s watermelon and feta salad for a juicy, refreshing contrast to all that deli meat. You do need to subscribe to cook these recipes, along with the tens of thousands of others at New York Times cooking. Improvise Your Melon SaladsTo make Eric’s watermelon salad even more colorful, substitute sliced cucumber and cantaloupe for some of the watermelon. Or use any combination of melons here; the simple olive oil, feta and basil dressing will work brilliantly with whatever you have.
Persons: Gabriella Lewis’s, Slagle’s, Eric Kim’s Organizations: New York Times Locations: Italian
CNN —The bones of teens and young adults who lost significant weight after bariatric surgery were weaker than those of youth with similar levels of obesity who did not have surgery, a new study found. Despite counseling, teens and young adults who did not undergo weight loss surgery continued to gain weight over those two years, the study found. However, it’s difficult to accurately study bone loss in adolescents and young adults. A study would need to follow teens who underwent surgery for at least 10 years to determine if the bone loss seen in the new study lasts, Inge said. “That’s why we insist that people undergoing weight loss surgery take their multivitamin with calcium and vitamin D every day, just like medicine.”
Persons: Miriam Bredella, , ” Bredella, Don’t, Thomas Inge, Robert H, Lurie, , Inge, they’re, Bredella, it’s, Justin Ryder, Ryder, Heike Faber, iStockphoto, haven’t, ” Ryder, ” Inge Organizations: CNN, Harvard Medical School, Massachusetts General Hospital, Ann, Lurie Children’s Hospital of Chicago, NASA, BMI, Northwestern University’s Feinberg School of Medicine, Locations: Massachusetts, Boston, Chicago
When hedge fund Three Arrows Capital collapsed last year, it left the crypto world reeling. But the firm's founders, Kyle Davies and Su Zhu, have reportedly had it pretty good ever since. Just because your crypto firm collapsed, doesn't mean you are going to end up on house arrest at your parents' pad. As the liquidation process began for their crypto firm, both founders flew to Bali — Indonesia notably doesn't have an extradition treaty with the United States — the Times reported. According to the Times, Zhu started to hang out with surfers and UFC fighters.
Persons: Kyle Davies, Su Zhu, Zhu surfed, Davies, Hemingway, Zhu, liquidators Organizations: Arrows Capital, Morning, New York Times, United, Times, Twitter, UFC Locations: Bali, Bali — Indonesia, United States, Bahrain, Singapore
Orcas also have very wrinkly brains, which enables them to think and process information quickly. Orca and human brains are very similarHuman brains and orca brains have similar regions that make both animals highly sociable, empathetic, and intelligent. Joel W. Rogers/Getty ImagesAn orca's brain is five times larger than a human's, but it has many of the same structures that ours do. In fact, the paralimbic system in orca brains has much more intricate folding and detail than human brains do. Now imagine an orca's brain which is five times larger and has way more wrinkles.
Persons: Orcas, , They've, Joel W, Lori Marino, Serge Melesan, orcas, Gerard Soury, It's, Marino, South Africa —, Matthew Horwood Organizations: Service, Rogers, The, Sanctuary, Orca Network Locations: South Africa
This Sweet-Tart Roasted Salmon Is Ready in No Time
  + stars: | 2023-05-31 | by ( Melissa Clark | ) www.nytimes.com   time to read: 1 min
It’s easy to forget that rhubarb is a vegetable. Much of the time, you’ll find it buried, like a fruit, under an avalanche of sugar baked into a pie, crumble or cake, or maybe simmered into a compote. With a bracing acidity reminiscent of citrus or pomegranate and no pesky seeds, it lends brightness and tang to all sorts of savory dishes. It also adds body, cooking down into a thick sauce with a soft, pulpy texture much like tomato (an actual fruit), though sharper and pinker. Think vinegar, but with precision and finesse.
Persons: pinker
But killer whales, or orcas, are actually members of the dolphin family. Killer whales aren't whalesKiller whales are not actually whales, but dolphins. The name "killer" whale isn't from killing humansOrcas are not called killer whales because they're whales that kill humans. Killer whales don't eat just anything that comes their wayContrary to popular belief, orcas are actually pretty picky eaters. Though killer whales may be misunderstood, you definitely shouldn't get a closer look at them.
Researchers conducted a study to find out how different human body odors can attract mosquitoes. The research used a 20-meter by 20-meter screened cage that contained hundreds of African malaria mosquitoes, according to the study. Despite the name, the mosquitoes were not infected with malaria, according to CNN, which first reported on the study. These tents are connected to the cage in a way that the human body odor can be safely fed to the mosquitoes. Researchers found that mosquitoes gravitated to human body odor with "increased relative abundances of the volatile carboxylic acids," including butyric acid.
The U.S. Food and Drug Administration's (FDA) briefing document highlighted increased risk of diabetes and liver injury from using the obeticholic acid (OCA) oral tablets for the treatment of nonalcoholic steatohepatitis (NASH). "During the course of our review, FDA identified modest benefits and serious risks of OCA for treatment of NASH," the staff said in the document and listed increased risk of sludge formation in the gall bladder and imbalance of certain lipids. The staff asked the regulator's panel of outside advisors, who are meeting on Friday, to consider whether the modest benefits from using the drugs for NASH treatment outweigh the serious risks associated with it. The panel's meeting on Friday is the first such meeting for a NASH treatment. However, due to risks of serious liver injury, FDA restricted its usage in 2021 to primary biliary cholangitis patients with advanced cirrhosis, or severe liver scarring.
During his snooze, the study team will analyze Woofus’ brain waves to judge the quality of his sleep. John Joyner/NC State Veterinary MedicineTraining the dogs to accept EEGTo find out whether sleep problems in dogs indicate early signs of dementia as they do in people, Olby and her team turned to a group of senior dogs enrolled in an ongoing study testing antiaging supplements. John Joyner/NC State Veterinary MedicineFor the new study measuring a dog’s brain waves during sleep, researchers used a form of electroencephalogram called polysomnography, used in sleep clinics to diagnose sleep problems in people. Jake, a 13-year-old pointer, was one of 28 dogs trained to sleep with EEG electrodes. When sleeping brain waves were compared with a dog’s cognitive testing, researchers found that dogs with greater dementia spent less time in deep and REM sleep, just as people do.
Yotam Ottolenghi Celebrates Spring With Asparagus
  + stars: | 2023-05-10 | by ( Yotam Ottolenghi | ) www.nytimes.com   time to read: +1 min
In her cookbook “Salt, Fat, Acid, Heat,” Samin Nosrat reduces two cups of heavy cream — add olive oil and Parmesan in very generous amounts — in an asparagus-and-mint pasta. Alice B. Toklas tossed her asparagus in melted butter and heavy cream. But as she served it, she whipped up some more heavy cream, seasoned with salt and pepper, to ward off any false sense of restraint. You can take a minimalist approach and roast your asparagus spears with some oil and salt. I also love Alice Waters’s classic salad of raw, thinly shaved asparagus with vinaigrette and Parmesan.
Six innovations that can help feed the world
  + stars: | 2023-05-09 | by ( Mark Tutton | ) edition.cnn.com   time to read: +8 min
CNN asked three experts to outline the innovations that can help increase food production without harming the planet. Insect proteinSingapore-based Insectta uses black soldier fly larvae to convert organic food waste into fertilizer and animal feed. The maggots are fed food waste, such as the byproducts of soybean factories and breweries. Don Emmert/AFP/Getty ImagesMadramootoo says that a wholescapes approach can also be applied to food production in urban and peri-urban areas – the spaces immediately surrounding a city. “In congested peri-urban areas, we can use vertical farms in warehouses or abandoned buildings, for example, to produce food.
CNN —Sarracenia pitcher plants, found in bogs throughout eastern North America, look like trumpet-shaped flowers, often in purplish or reddish hues. Different kinds of Sarracenia pitcher plants tend to eat different kinds of insects — some species trap more ants, while others feast on bees and moths. But recently opened pitcher plants that don’t stink of rotting bug carcasses provide an opportunity to identify the scents, she explained. The biggest challenge with the study, honestly, is that they did it in France,” rather than in the Sarracenia pitcher plants’ native North American bogs. It’s important to study pitcher plants due to the unique role they play in their increasingly fragile ecosystems, he added.
As emergency doctors, here are seven longevity snacks we eat to stay healthy, full and energized all day:1. HummusChickpeas, the main ingredient in hummus, are high in fiber and a great source of plant-based protein. Studies have found that adding it to your diet can help protect against heart disease, Type 2 diabetes and certain cancers. A 2016 study found that eating more monounsaturated fat reduced the risk of premature death due to disease, compared with eating more carbohydrates. Olives are often soaked in brine, and over time, snacks high in salt can lead to increased blood pressure.
March 22 (Reuters) - Drug developer 89Bio Inc <ETNB.O> said on Wednesday its experimental treatment for liver disease NASH met the main goals of a small mid-stage study, sending its shares 30% higher. The drug, pegozafermin, helped reduce liver scarring known as fibrosis as measured on two different scales in patients with NASH, or nonalcoholic steatohepatitis, trial data showed. 89Bio said the drug, administered both weekly and every two weeks in the trial, had a safety profile similar to older trials. In the trial, the drug helped significantly reduce fibrosis or liver scarring without the worsening of NASH, compared to a placebo. NASH, a form of non-alcoholic fatty liver disease, is characterized by the organ developing fibrosis or scarring, which can progress to cirrhosis and liver failure.
The Food and Drug Administration said updated mammography regulations will help provide important information that could affect patient care. The U.S. Food and Drug Administration has updated its mammography regulations to require that women be notified if they have dense breast tissue, which can make imaging less precise and cancer harder to find. About half of women over the age of 40 in the U.S. have dense breasts, with more fibrous and glandular tissue than fatty tissue, according to the FDA. Not only can dense tissue make it harder for cancers to be detected in a mammogram, it has also “been identified as a risk factor for developing breast cancer,” the FDA said in a statement Thursday.
General Electric has jumped 42.9% this year, more than recovering form last year's 11.3% drop. Roughly three-fifths of analysts covering the stock rate it a buy, with the average price target implying a 12.5% gain over the next 12 months. On Monday, On entered into a long-term supply agreement with BMW to support technology in the automaker's next generation of electric vehicles. Just under three-fifths of analysts rate the stock a buy, with the average analyst's price target showing shares should rise 9.6% in the next year. The stock is liked by about three-fifths of analysts covering it, and the average price target implies upside of 11.6%.
While imitation crab is more affordable than real crab, it doesn't have as much nutritional value. Once imitation crab hit the markets in the late '70s, it became wildly popular as an affordable alternative to crab meat. Yet while real crab packs a major protein punch, imitation crab doesn't have quite as much nutritional value. Imitation crab contains little or no real crab. Brian Vander Brug / Contributor / Getty ImagesThe rising costs of crab have made imitation crab a more appealing option for many shoppers.
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