[1/2] Ron Klain attends a meeting at the Oval Office of the White House in Washington October 22, 2014.
REUTERS/Kevin Lamarque/File PhotoREHOBOTH BEACH, De., Jan 21 (Reuters) - Ron Klain, President Joe Biden's White House chief of staff, plans to leave his post in the coming weeks, sources familiar with the matter said on Saturday, a major changing of the guard.
Klain, 61, has a long history at the White House, having served as chief of staff to former Vice President Al Gore and to Biden when he was vice president under President Barack Obama.
The chief of staff position is one of the most important at the White House, the senior political appointee responsible for driving the president's policy agenda and ensuring appropriate staff members are hired.
Biden's predecessor, Republican Donald Trump, burned through four chiefs of staff in four years including his first, Reince Priebus, who lasted 192 days.