Second seed Sakkari powered past Dolehide, who is ranked 111th in the world, for a 7-5 6-3 victory to capture her second career title, ending the week without dropping a set.
Sakkari had lost six finals since winning her first title at the WTA 250 tournament in Rabat in 2019.
"We've heard so many bad things - that I will never win a title, that I'm a top-five player with only winning one title," said Sakkari, who broke down in tears after her win.
We've waited for more than four years for a second title."
In Saturday's final, Dolehide rallied from a break down in a tight opening set to take a 5-4 lead, but Sakkari won the next three games to take the set.
Persons:
Maria Sakkari, Caroline Dolehide, Henry Romero, American Caroline, Sakkari, Jessica Pegula, We've, Tom, Dolehide, Hritika Sharma, Jamie Freed
Organizations:
Panamerican Tennis Center, U.S, REUTERS, WTA, Thomson
Locations:
Guadalajara, Mexico, Greece, American, Rabat, Hyderabad