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Blood biomarkers of telltale signs of early Alzheimer’s disease in the brain of his patient, 55-year-old entrepreneur Simon Nicholls, had all but disappeared in a mere 14 months. “I don’t use the term ‘reverse.’ I don’t know what reverse means when it comes to the field of Alzheimer’s,” Isaacson said. ‘It was time to turn to my brain’Slowly, Nicholls’ heart condition began to improve, but the bad news didn’t end there. A brain scan found telltale signs of vascular damage in Nicholls’ brain, which occurs when the tiniest blood vessels are starved of oxygen. Not only was Nicholls blood negative for amyloid and tau, the test suggested that his brain amyloid might be normal, with no distinguishable signs of the disease.
Persons: Sanjay Gupta, Anderson Cooper ”, Richard Isaacson, Simon Nicholls, , , Isaacson, “ Simon, ” Isaacson, Nicholls, ” Nicholls, Anderson Cooper, It’s, APOE4, Simon, ” Simon Nicholls, Sylver, Lewy, Richard Isaacson ‘, APOE ε4, “ I’ve, Isaacson doesn’t, “ I’m, Shocked, Dr, we’d, “ It’s, Salvadore, Richard Isaacson “, ‘ It’s, I’m Organizations: CNN, telltale, ” CNN, Boca Raton Locations: Boca Raton , Florida, New York City, Florida, Nature, Miami, Isaacson’s Florida, tirzepatide
The storm also battered New Orleans overnight, with severe thunderstorms and flooding possible again Friday, according to the local branch of the National Weather Service. A home is severely damaged by a fallen tree after heavy winds and rains ripped through the region on May 17, 2024 in Houston, Texas. Across Houston, photos and videos on social media showed intense flooding and downed trees, as well as toppled electrical towers and power lines. Another video showed baseball fans leaving the stadium amid the bad weather. Strong winds appeared to have blown off roof panels at a Hyatt Regency Hotel in Houston, a video posted to X showed.
Persons: Melissa Phillips, Ike, Houston Mayor John Whitmire, Logan Riely, Harris, Lina Hidalgo, Hidalgo, Samuel Peña, Whitmire, Greg Abbott, Abbott, Brett Coomer, Jon Shapley Organizations: Hearst Newspapers, Getty, Houston Mayor, National Weather Service, Houston Independent School District, Houston Fire, Texas Gov, Texans, Facebook, Houston Astros, Hyatt Regency Locations: Parkway, West, Cypress, Texas, Houston, Romayor, New Orleans, Houston , Texas, Southeast Texas, Sowden, Houston's Harris County, Fargo Plaza
Scheffler faces charges of second-degree assault of a police officer, third-degree criminal mischief, reckless driving and disregarding traffic signals from an officer directing traffic. Scheffler’s arraignment is scheduled for Tuesday at 9 a.m., according to online court records, two days after the PGA Championship is scheduled to end. The PGA of America and Louisville Mayor Craig Greenberg said in separate statements that their primary concern was with Mills’ family. AdvertisementWhen Scheffler stopped the car, an officer opened the door to arrest him, Darlington reported. Scheffler, the defending Masters champion and winner of four of his last five starts, entered Friday tied for 12th place.
Persons: — Scottie Scheffler, Scheffler, ” Scheffler, John Mills, Louisville Mayor Craig Greenberg, Mills, ” Greenberg, , , ESPN’s Jeff Darlington, Scheffler “, Bryan Gillis, Gillis, Darlington, ” John Bradley, ‘ I’m, I’m, Steven Romines, teed, — Ben Burrows, Michael Reaves Organizations: PGA, Golf, Louisville Metro Police, America, Louisville Mayor, ” Police, Louisville Police Department, Louisville Metropolitan Department of Corrections, Louisville, Louisville police Locations: LOUISVILLE, Ky, Louisville, Valhalla
Buying a houseboat: 'It felt like the perfect place for me'I visited one of the houseboats the following week. Moving aboard: 'The best decision I ever made'Going straight into a Canadian winter as a houseboat novice is generally considered a poor decision. Three years later, I regard buying my houseboat as the best decision I ever made. Courtesy of Kate FinchamMy bathroom has a typical residential toilet (which flushes into a holding tank below) and a bathtub. This area acts as my living room, dining room, and office, and features a wood stove and sliding glass doors that exit onto my back deck.
Persons: I've, I'd, Kate, Kate Fincham, Charlie, Finn, it's Organizations: Swans, Insurance Locations: Toronto
Mahmoudi is the clinical director of sleep medicine in the Division of Pulmonary, Critical Care and Sleep Medicine at NYU Langone Health. "I've sent a lot of my patients for a 10-day trip to Europe as a vacation." For night owls, it can be difficult to acclimate to the 9-to-5 world , but one sleep expert has an interesting approach to help some of her U.S.-based clients who are night owls adjust to an earlier schedule. Night owls go to bed and wake up later than others due to their natural circadian rhythms. "But the consistency after [the trip] is important because you genetically are a night owl," Mahmoudi says.
Persons: Mahmoudi, Mandana Mahmoudi, I've Organizations: Sleep Medicine, NYU Langone Health, CNBC Locations: Europe, .
Discover Le Havre, Where Impressionism Was Born
  + stars: | 2024-05-10 | by ( Elaine Sciolino | ) www.nytimes.com   time to read: 1 min
As the fog of dawn lifted one morning in mid-November 1872, Claude Monet looked out the window of his hotel room in the French city of Le Havre and furiously painted his vision of its industrial harbor. He flung his brush with quick strokes and played with the water, stretching it with rays of color. In one sitting, he created “Impression, Sunrise,” a painting of a vivid orange sun with its reflection shimmering in the sea. In 1874, Monet, who grew up in Le Havre on the Normandy coast, included the painting in an exhibition of 30 artists’ work organized in response to the Paris Salon, an annual showcase of academic art. “I thought to myself, this has made an impression on me so there must be impressions somewhere in there.”
Persons: Claude Monet, Le Havre, Monet, Louis Leroy, , Organizations: Paris Salon Locations: French, Le, Le Havre, Normandy
Plenty of retailers have kicked off Mother's Day sales to make it easier to get a thoughtful present without breaking the bank. No matter what type of mom you have, we've gathered the best Mother's Day deals on flower delivery, jewelry, smart photo frames, and more. 5 best Mother's Day sales 1-800-Flowers: Get up to 40% off Mother's Day arrangements. More Mother's Day salesFrequently asked questionsWhen is Mother's Day? The best Mother's Day sales typically kick off well before the actual holiday since they're intended to help shoppers score discounts on gifts in time for the day of.
Persons: we've, Mason, Farmgirl, they're Organizations: Business, Mother's, Apple, Amazon, Metro Locations: Oslo
My children came out to me one summer; they both started HRT to help with their body dysmorphia. I worry about the dangers of being trans in this world, but I am trying to be courageous. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . Both of my kids came out one summerI've always considered myself to be someone who could handle or adapt to anything. While I can't say HRT has been the cure-all, I can say that it has made a monumental change in their self-esteem and their confidence.
Persons: , I'm, We're LatinX Organizations: HRT, Service, It's Locations:
Plenty of retailers have kicked off Mother's Day sales to make it easier to get a thoughtful present without breaking the bank. No matter what type of mom you have, we've gathered the best Mother's Day deals on flower delivery, jewelry, smart photo frames, and more. It's still early, so we expect plenty more Mother's Day sales to kick off as the holiday approaches. 5 best Mother's Day sales 1-800-Flowers: Get up to 40% off Mother's Day arrangements. More Mother's Day salesFrequently asked questionsWhen is Mother's Day?
Persons: we've, It's, Mason, Farmgirl, they're Organizations: Business, Mother's, Apple
Known for his hit songs like "I Remember Everything," "Something in the Orange," and "Heading South," Zach Bryan's 2024 tour celebrates his self-titled album that debuted in 2023. We've got you covered if you're looking to buy tickets to Zach Bryan's 2024 Quittin Time Tour. Zach Bryan 2024 tour scheduleZach Bryan has only just begun his tour, with more than 60 shows remaining throughout 2024. How to buy tickets for Zach Bryan's 2024 concert tourYou can buy standard original tickets to Zach Bryan's 2024 tour through Ticketmaster and AXS. Prices for tickets to Zach Bryan's 2024 tour vary depending on date, location, and demand.
Persons: Zach Bryan, Zach Bryan's, We've, Bryan, Zach Bryan's Atlanta, Jason Isbell, Sheryl Crow, Sierra Ferrell, Matt Maeson, Levi Turner, Here's, MN Sheryl Crow, Sierra, Louis ,, Zach Bryan hasn't Organizations: Business, Vivid, SC, Springs, Las, Kansas City, KY, UT, Ticketmaster, FL, Sierra Ferrell, TN Locations: Brooklyn, Bryan's, Tulsa , Oklahoma, Canada, Brooklyn , New York, Omaha, Louis, Greenville, Knoxville, TN, Oklahoma, Oakland, Los Angeles, CA, Las Vegas, Denver, Detroit, MI, Columbus, Nashville, Orlando, Orleans, LA, Houston, Antonio, Greensboro, NC, Philadelphia, Atlanta, Tampa, Arlington, TX, Kansas, Minneapolis, Forks, Louisville, Edmonton, Vancouver, BC, Tacoma, WA, Portland, Sacramento, Glendale, AZ, Salt Lake City, Tulsa, NY, Columbus , Ohio, Arlington , TX, Philadelphia ,, MN, Antonio ,, Greensboro , NC, Kansas City ,, Tacoma , WA, Sacramento , CA, Columbus ,, Edmonton , Alberta, Vancouver , British Columbia
Read previewThe Lyrid meteor shower is in full swing this week. The meteor shower was most active from Sunday night to Monday morning, but it will remain visible for the next week. On Tuesday night, the Lyrids align with the April full moon, otherwise known as the "pink moon," which will rise at 7:49 p.m. It's a stunning sight all on its own, but seeing it during a meteor shower is a rare astronomical opportunity. AdvertisementBut again, because of the bright "pink" supermoon, stargazers may not see as many as they hope.
Persons: , you've, stargazers Organizations: Service, Business, Hemisphere, NASA Locations: moonset
The Airbus plane had previously been used by King Charles, Queen Camilla, and other UK officials. AdvertisementA plane used by VIPs like King Charles and Queen Camilla had to make an emergency landing after three windowpanes fell out mid-flight. The lights, used to convey a sunrise, had been aimed at the windows for several hours at a time, the report said. A hole burned through one of the windows while five other windows were deformed after 2,000W lights were used, the report said. If high-intensity lights were used, it suggested keeping use to a minimum and away from windows.
Persons: King Charles , Queen Camilla, , King Charles, Queen Camilla, Charles, Camilla, Charles III, Tim Rooke, Rishi Sunak, James Organizations: Titan Airways, Airbus, Service, Air, Investigation, Telegraph, Airport, British, Business, Investigation Branch, Boeing Locations: London, Orlando, British, France, Paris, Buckingham
The relatively limited scope of Israel’s overnight strikes on Iran, and a subdued response from Iranian officials, may have lowered the chances of an immediate escalation in fighting between the two countries, analysts said Friday. For days, there have been fears that a forceful Israeli response to Iran’s attack on southern Israel last weekend could prompt an even more aggressive riposte from Iran, potentially turning a tit-for-tat confrontation into a wider war. But when it finally came early on Friday, Israel’s strike appeared less damaging than expected, allowing Iranian officials and state-run news outlets to downplay its significance, at least at first. By sunrise, Iranian state-run news outlets were projecting a swift return to normality, broadcasting footage of calm street scenes, while officials publicly dismissed the impact of the attack. But the initial Iranian reaction suggested that Iran’s leaders would not rush to respond, despite warning in recent days that they would react forcefully and swiftly to any Israeli strike.
Persons: Israel, Israel’s, Iran — Organizations: Iran’s Locations: Iran, Israel, Isfahan
Queer and transgender Muslims came together to break their Ramadan fasts. But for queer and transgender Muslims, this practice of ummah, or the connectedness Muslims feel while exercising their faith together, has often made them feel excluded from traditional Ramadan celebrations. Courtesy of Dinean RobinsonThe iftar — which included prayers led by a queer Muslim community member named Shiffa, and joyful drag-queen performances — was just one of many ways queer and transgender Muslims fostered community this Ramadan. Dena Igusti celebrated this Ramadan with fellow queer Muslims, saying it helped them get back in touch with their faith. In New York City, queer Muslims joined in song and dance at the LGBT Community Center's iftar to celebrate their layered identities.
Persons: , affirmations, I've, Armana Khan, Dinean Robinson, Khan, Islam, Reimagining, they'd, Kahani, Dinean Robinson Sophia Uppal, Uppal, wouldn't, Dena Igusti, Ramie Ahmed, Ramadan, Igusti, Imam Daayiee Abdullah, We're, MASGD, Shiffa, Center's iftar, Yaffa Organizations: Service, LGBT Community, The, New York, LGBT Community Center, BI, Mecca Institute, Muslim Alliance, Sexual, Diversity, Queer, Shia, LGBT Locations: New York, queerness, Queens , New York, New, Hajj, Mecca, Palestinian, New York City
Looking for a Fight
  + stars: | 2024-04-17 | by ( Tyler Hicks | Photographs | ) www.nytimes.com   time to read: 1 min
The bullet-scarred pickups raced the sunrise along a rough dirt road wending through a dense pine forest. Multiple languages were spoken by the men inside them — Ukrainian, Brazilian, Colombian, Polish — but few words. They had come to fight Russians. The trucks barely came to a halt to discharge their passengers before speeding off again. Armed drones might appear overhead at any moment, and so as the men continued on foot, they, too, did so with urgency.
Organizations: International Legion Locations: Polish
Alain BeechingThe researchers also reviewed skeletons found at other archaeological sites across Europe and identified 20 other probable instances of similar sacrificial killings. The practice may have been relatively widespread in Neolithic, or late Stone Age, Europe, according to the study, published in the journal Science Advances last week. The study said the actual number was probably higher but there was insufficient information about skeletons at other archaeological sites to draw firm conclusions. The three skeletons were buried in a grave built in the style of a silo, where grain is typically stored, inside a wooden structure and surrounded by a trench. At the other sites across Europe, men and children as well as women were also found sacrificed in this way, the study said.
Persons: CNN —, Alain Beeching, ” Éric, Crubézy, ” Crubezy, Châteaux, , Nicolas Senegas, Ameline Alcouffe Organizations: CNN, Italian Mafia, Paul Sabatier University, Saint Locations: France, Saint, Europe, Toulouse, South America
There are three types of space tourism companies now vying to open up this experience to the wealthy, the superwealthy and the out-of-this-world wealthy. HALO SpaceLast week in London, HALO Space CEO Carlos Mira unveiled the interior design for its Aurora space capsule, which his team hopes will transport 10,000 passengers to near-space by 2030. HALO Space declared at the presentation that it’s offering “new, safe and zero-emissions alternatives to space flights,” and having already completed five successful test flights, that it’s the most advanced company in its sector. Within a very limited space, comfortable seating, generous viewing windows, storage areas and, most importantly, a toilet cubicle all had to be integrated. Flights will launch pre-dawn, so that guests can experience a “white” sunrise at the edge of the stratosphere with the deep black of space beyond.
Persons: what’s, , Yuri Gagarin, , there’s Elon, Jeff Bezos, Richard Branson’s Virgin, Carlos Mira, Frank Stephenson, Alpha Romeo, Mira, Stephenson Organizations: London CNN, SpaceX, Richard Branson’s Virgin Galactic, HALO Space, Ferrari, CT Engineering, HALO Locations: Soviet, there’s, London,
People watch the first sunrise of the new year from a footbridge overlooking the city skyline in Seoul on January 1, 2024. The opposition Democratic Party (DP), which already dominates the 300-member legislature, has accused Yoon and his conservative People Power Party (PPP) of mismanaging the economy and failing to rein in inflation during their time in office. PPP leader Han Dong-hoon said a big win by the DP, whose leader is facing corruption charges, would create a crisis for the country. He warned against giving the opposition an unprecedented super majority of 200 seats, which would strip Yoon of his veto power. "I hope the two-party structure will be broken somehow, and politicians will carry out practical policies for ordinary people."
Persons: Yoon Suk Yeol, Yoon, Han Dong, hoon, Kim Ji, yun, Jung Cheol, Cho Kuk Organizations: South, Election, Democratic Party, People Power Party, DP Locations: Seoul
A photo taken by Abdallah Dalee in the early hours of February 29 shows a crowd of people waiting by firelight for the aid trucks to cross into northern Gaza. Mark Regev, the Israeli prime minister’s special adviser, initially told CNN that Israeli forces had not been involved. “Most of the people that were killed were rammed by the aid trucks during the chaos and while trying to escape the Israeli gunfire,” Al Za’anoun said. The footage shows hundreds of people gathering around aid trucks on Al Rashid Street. People mourn outside Al-Shifa hospital in Gaza City over one of the Palestinians killed during the aid delivery on February 29.
Persons: Abu Watfa, ” Abu Watfa, , , Al Rashid, Abdallah Dalee, firelight, Abdallah Dalee Gazan, Mark Regev, Daniel Hagari, Al Za’anoun, ” Al Za’anoun, Rashid, Belal, Robert Maher, Richard Weir, Weir, Al Jazeera, , Abd Rabu, Hamouda Zamil, Dr, Amjad Aliwa, Georgios Petropoulos, ” Mohammed Ahmed, I’ve, ” Ahmed, Ahmed Organizations: CNN, United Nations, Israel Defense Forces ’, IDF, Montana State University, Human Rights Watch, Al, AFP, Getty, Welfare Trust, Welfare, Ummah Welfare, UN Office, Human Rights Locations: Gaza City, Gaza, Israel, Al, United States, Bolton, England, , Al Nabulsi, Al Kuwaiti
Hungry at 3 am? You’re out of luck now
  + stars: | 2024-04-06 | by ( Nathaniel Meyersohn | ) edition.cnn.com   time to read: +6 min
Not even all of 24 Hour Fitness’ gyms — the promise is right in its name — are 24 hours. The city that never sleeps, New York, has lost 13% of its 24-hour restaurants. Around half of IHOP’s 1,800 locations are back to being open 24 hours on Friday and Saturday, at the very least. Ed Endicott/Alamy Stock Photo/FilePete’s was open 24 hours, seven days a week from the 1990s until the pandemic hit in 2020. Despite the signage, Mi Tierra is no longer open 24 hours in San Antonio, Texas.
Persons: hasn’t, Waffle, , Alex Barakos, Ed Endicott, Pete’s, Barakos, , Hudson Riehle, Edward Hopper’s, Harold, Kumar Go, Stephen Zagor, Pete Cortez, Michael Silver Geo, “ There’s, ” Cortez, ’ ” Cortez Organizations: New, New York CNN, Walmart, Hollywood, Alamy, Bureau of Labor Statistics, , National Restaurant Association, Edward Hopper’s Nighthawks, Columbia Business School, of Locations: New York, Covid, Los Angeles, Chicago, Denver, Philadelphia, White, , New York City, San Antonio, Mi, San Antonio , Texas, Tierra, tuxedos
I spent two months living in one of my bucket-list destinations — the tropical island of Bali. The beaches were mostly a letdownThe beaches in Bali aren't necessarily bad, and some are really nice. But walking anywhere in Ubud felt far more chaotic than the romantic drama "Eat, Pray, Love" depicts. Jonathan LevinIndonesia's Gili Islands are not technically part of Bali, but ferry trips to it are popular among Bali visitors, so it feels worth mentioning. AdvertisementOn one side of the island, there's a very narrow strip of sand that seemed to be mostly privatized.
Persons: , Hugo Amaral, Jonathan Levin, Ubud, I'm, Canggu, pesky, Jonathan Levin Indonesia's Organizations: Service, Business, Gili Locations: Southeast Asia, Bali . Bali, Bali, it's, Nusa Penida, Ubud, Central
CNN —When the total solar eclipse traces a path across Mexico, the United States and Canada on April 8, spectators can anticipate a multitude of awe-inspiring moments. For those living outside of the path of totality, a crescent-shaped partial eclipse, rather than a total eclipse, will be the main event. A partial solar eclipse is seen between clouds from Socorro in Sao Paulo, Brazil on October 14, 2023. The diamond ring effect is seen during the total solar eclipse on August 21, 2017, in St. Louis, Missouri. And we’re living at the right time to truly enjoy the sight of a total eclipse on Earth, he said.
Persons: , John Mulchaey, Crawford H, Greenewalt, it’s, Robyn Beck, Igor, ” Mulchaey, , It’s, you’re, Mulchaey, Francis Baily, Heinz, Peter Bader, X00316, Tim Spyers, Andrew Farnsworth Organizations: CNN, Carnegie Institution, Carnegie, NASA, Cornell, of Ornithology Locations: Mexico, United States, Canada, , Prairie, AFP, Socorro, Sao Paulo, Brazil, St, Louis , Missouri
“I understand concepts, I comprehend things, I have memories, but they aren’t supported by any images,” Wathen said. Paul BokslagDutch-born artist Geraldine van Heemstra is at the opposite end of this unique way of processing. In reaction to cruel teasing from her brothers and school friends, van Heemstra learned to hide her sensory abilities as a child. “It was quite tricky at school as well, such as with math, where I would see the numbers in color,” van Heemstra said. “It was so frustrating at school because I would explain something, and then I would be laughed at,” van Heemstra said.
Persons: Mary Wathen, ” Wathen, , Wathen, , “ I’ve, ‘ You’ve, Geraldine van Heemstra, Paul Bokslag Dutch, van, ” van Heemstra, “ It’s, van Heemstra, van Heemstra can’t, aphantasia, Adam Zeman, Zeman, ” Zeman, aphantasia don’t, ” That’s, I’m, they’ve, that’s, what’s, Van Heemstra, ” Van Heemstra, you’re Organizations: CNN, University of Exeter, University of Edinburgh, Cognitive Sciences, Locations: Newent, England, Scottish, London, Edinburgh, Scotland, Miami
The Biden administration greenlit the seventh large offshore wind project in the United States Tuesday. Danish wind energy developer Ørsted and the utility Eversource plan to build a 924-megawatt project, Sunrise Wind, 30 miles (48 kilometers) east of Montauk, New York. This month, the companies opened the nation's first commercial-scale offshore wind farm. They announced their financial commitment to the Sunrise Wind project when the Interior Department issued its decision. The Biden administration wants enough offshore wind energy to power 10 million homes by 2030.
Persons: greenlit, Ørsted, Chuck Schumer, Biden, Deb Haaland Organizations: Biden, Interior Department, U.S, Sunrise, Associated Press Locations: United, Montauk , New York, York, Montauk, Fork, AP.org
Spring equinox: First day of spring arrives
  + stars: | 2024-03-19 | by ( Forrest Brown | ) edition.cnn.com   time to read: +7 min
The spring equinox will arrive exactly at 3:06 UTC (Coordinated Universal Time) on Wednesday, March 20, according to EarthSky. Click here to look up the exact moment of the spring equinox where you’re located. Spring equinox has another nameIf you ever hear anyone say “vernal equinox,” it means the same thing. Zhang Xiaoyu/Xinhua News Agency/Getty ImagesIn Japan, Vernal Equinox Day is a public holiday (on Wednesday, March 20, this year). In China, trying to stand an egg upright is a popular game during the spring equinox, according to VisitBeijing.com.
Persons: Tuesday •, , • Chiang Mai, David Silverman, Alex Pena, It’s, you’ve, it’s, Hugo Borges, Itzá, El Castillo, Zhang Xiaoyu, Organizations: CNN, Tuesday, United, Southern, Anadolu Agency, Getty, NASA, Northern Hemisphere, Northern, Southern Hemisphere, National Weather Service, Heritage, Xinhua News Agency Locations: • Anchorage, Alaska, Vegas ( Nevada, Tuesday • Guadalajara, Mexico, Chicago, Illinois, Toronto, Canada, Jacksonville, Florida, Halifax, • Dublin, Ireland, Accra, Ghana, • Berlin, Germany, • Alexandria, Egypt, • Ankara, Turkey, • Dubai, United Arab Emirates, • Mumbai, India, Thailand, • Hong Kong, • Tokyo, Japan, Stellenbosch , South Africa, Northern, South, Quito, Ecuador, Singapore, San Andrés, Zapotitán, El Salvador, Pole, Scandinavia, Itzá, Yucatan State, AFP, England, Malta, Yoyogi, Tokyo, Vernal, Persian, China
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