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☆ Europe will lose out on medical innovation if draft EU reforms pass -Novo Nordisk CEO
▼ + stars: | 2023-03-02 | by ( Maggie Fick | ) www.reuters.com time to read: +3 min

LONDON, March 2 (Reuters) - Europe will lose out to countries like the U.S. and Japan on new medical research, trials and treatments unless draft rules reforming the European pharmaceutical landscape change, the CEO of Danish drugmaker Novo Nordisk (NOVOb.CO) warned on Thursday. It says drugs need to reach patients more quickly and in all European nations. Novo's Lars Jorgensen lamented that without changes to the current draft, his company would be forced to research, test and bring products in its pipeline to market in the United States and elsewhere, instead of in Europe. A lose, lose, lose," he said in an interview. The Commission's current draft was leaked in Brussels last month and will likely change even before debate in the European parliament and among governments.

☆ Leipzig's Orban to donate stem cells, doubtful for Union game
▼ + stars: | 2023-02-07 | by ( ) www.reuters.com time to read: +1 min

BERLIN, Feb 7 (Reuters) - RB Leipzig's Willi Orban will become a stem cell donor for a blood cancer patient with a procedure on Wednesday and is doubtful for Saturday's Bundesliga match against second-placed Union Berlin, the club said on Tuesday. "He could now give another human being a second chance," the club said in a statement. Orban, who has missed training since Sunday to prepare with special injections, will undergo the harvesting procedure on Wednesday. Leipzig said it was unclear if he would feature in their league match against Union. "I might of course miss the Union game but even with my sporting ambitions, football is of secondary importance," he added.

☆ Rocker Ozzy Osbourne'not physically capable' of upcoming tour
▼ + stars: | 2023-02-01 | by ( ) www.reuters.com time to read: +2 min

LONDON, Feb 1 (Reuters) - British rocker Ozzy Osbourne said he was "not physically capable" of going on a European and UK tour this spring, as he was too weak for all the necessary travel involved in live shows. The 74-year-old has undergone years of treatment after a 2019 fall damaged his spine and exacerbated injuries from a 2003 quad bike accident. However, after three operations, stem cell treatments, endless physical therapy sessions, and most recently groundbreaking Cybernics (HAL) Treatment, my body is still physically weak," Osbourne said, referring to a treatment involving a mechanical exoskeleton. "Never would I have imagined that my touring days would have ended this way," Osbourne said. "My team is currently coming up with ideas for where I will be able to perform without having to travel from city to city and country to country."

☆ I'm a leg-lengthening surgeon. Most of my clients are men with confidence issues — here's what the procedure's like
▼ + stars: | 2023-01-29 | by ( Natalie Rahhal | ) www.businessinsider.com time to read: +14 min

Shahab Mahboubian performs 30 to 40 cosmetic limb-lengthening surgeries a year. The only field in medicine that uses all of these tools is orthopedic surgery, so it seemed like the right fit. I specialized in limb-lengthening surgery specifically because I wanted to do something that was different from everybody else. People that undergo limb-lengthening surgery are from all walks of life, and many used COVID lockdowns to recover post-surgery. I would say 80% to 85% of my cosmetic limb-lengthening patients are men, and 15% to 20% are women.

☆ Ketamine is being sold as a depression wonder drug. For some, it's making everything worse.
▼ + stars: | 2023-01-25 | by ( Anna Silman | ) www.businessinsider.com time to read: +42 min

The infusions at the ketamine clinic in his West Texas hometown were a Christmas gift from his grandmother. About five years ago, more and more of my friends started using ketamine recreationally. IV ketamine treatment centers charging $400 to $2,000 an infusion popped up all over the country. "Ketamine used as directed in an appropriate clinical setting very rarely leads to any dependence," Mindbloom says on its website. Like Nadia, most of the people I interviewed said when they started using ketamine, they didn't think it was possible to become dependent on it.

A Virginia bill would deem a pregnant person's fetus a passenger in a car, thereby allowing the vehicle to use the car pool lane on highways. Under the bill, the certifications would then be "linked" to toll collection devices — typically E-Z Passes — in vehicles. High occupancy lanes require drivers to have at least one passenger in their vehicles when they use the lanes. And by considering a pregnant person as two people — in this case, allowing a pregnant person to use an HOV lane — you're ultimately making it harder to uphold abortion rights, because you have essentially imbued a fetus with personhood," Nash added. Doug Ducey, a Republican, that included a provision, carried over from a 2021 law, that reproductive rights advocates say granted personhood to fetuses.

☆ When Does Life Begin?
▼ + stars: | 2022-12-31 | by ( Elizabeth Dias | Bethany Mollenkof | ) www.nytimes.com time to read: +19 min

“It is not black and white.”America’s fight over abortion has long circled a question, one that is broad and without consensus:When does life begin? The question of when life begins has been so politicized it can be hard to thoughtfully engage. Ancient Egypt gave the power to create new human life almost entirely to men. The scientific revolution, from Charles Darwin’s theory of evolution to reproductive science, disrupted centuries of thought on human life. “When does the responsibility for a life begin and end?”

☆ Here are 22 of the top LGBTQ news stories of 2022
▼ + stars: | 2022-12-30 | by ( Jo Yurcaba | Jo Yurcaba Is A Reporter For Nbc Out. | ) www.nbcnews.com time to read: +12 min

Here are 22 of our top LGBTQ news stories of the year. Ron DeSantis signed the controversial Parental Rights in Education law — or what critics have dubbed the “Don’t Say Gay” bill — on March 28. 'It’s already having an impact': LGBTQ people fear abortion rights reversalA supporter of gay marriage waves a flag in front of the Supreme Court on June 25, 2015. Nicola Goode / Prime VideoAmazon’s “A League of Their Own” series, which debuted Aug. 12 and was inspired by the 1992 cult classic by director Penny Marshall, brought much-needed representation to the screen for lesbians and other queer women, who celebrated how “gay, gay, gay” it was. Biden signs same-sex marriage bill at White House ceremonyPresident Joe Biden signs the Respect for Marriage Act on the South Lawn of the White House on Dec. 13.

☆ After a record-breaking 2021, European investors and founders are ready to take it slow
▼ + stars: | 2022-12-29 | by ( Jordan Parker Erb | ) www.businessinsider.com time to read: +4 min

Our Big Tech team was constantly chasing the biggest stories, from alleged executive misconduct at Microsoft to injuries in Amazon warehouses. After a record-breaking 2021, European startups raised $16 billion in the third quarter — a 44% annual drop. The solo founder joined YC in January 2022, and has since raised millions from investors like Alexis Ohanian. The risk of debilitating muscle and joint injuries at Amazon warehouses is off the charts, workplace regulators have said. Amazon workers shared why they planned to vote against unionizing.

☆ I got into Y Combinator as a solo founder and left with a $4.5 million investment. Here's how I got in on my second try and what it was like.
▼ + stars: | 2022-12-28 | by ( Claire Turrell | ) www.businessinsider.com time to read: +6 min

Kathryn Cross is the founder of Anja Health, a cord blood bank that freezes stem cells for future disease treatment purposes. I first heard about the startup accelerator Y Combinator when I was studying at Wellesley College and taking entrepreneurship classes at MIT. Many of the founders living in the house were in Y Combinator, and they told me how beneficial it was. I left my job with Publicis Sapient in June 2021 to begin working full-time for Anja Health. Did you go through Y Combinator and have a story to tell?

☆ Kids with 'bubble boy' disease could finally get access to a life-saving gene therapy, as a study starts back up at UCLA
▼ + stars: | 2022-12-27 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +4 min

UCLA researchers are restarting a study to give a gene therapy to kids with an ultra-rare disease. Without gene therapy, doctors treat kids with SCID using enzyme-replacement therapies, if they are ineligible for bone-marrow transplants. In an email to Insider, Kohn said he expects to be able to treat between three and six patients with his current funding. Drug companies have shown little interest in the treatments because the complexity of the treatments and tiny number of eligible patients limit potential profits. Drug companies have deprioritized or shelved gene-therapy programs to treat a range of rare diseases, including Wiskott-Aldrich syndrome, MPS, Batten disease, chronic granulomatous disease, Rett syndrome, and Fabry disease.

Pantone recently announced its 2023 Color of the Year: Viva Magenta. SKIP AHEAD Viva Magenta home products | Viva Magenta kitchen products | Viva Magenta beauty products | Viva Magenta apparel and accessoriesAs many sought to do with the 2022 Color of the Year, Very Peri, you may be interested in incorporating Viva Magenta into your wardrobe or home. Viva Magenta home productsThis expert-recommended rowing machine from Hydrow has a Viva Magenta option available for pre-order that is set to ship in February 2023, according to the brand. Pets can get in on the Viva Magenta trend with this plush bed, available in a color close to the new Pantone Color of the Year. Viva Magenta apparel and accessoriesPantone offers a handful of products in Viva Magenta, including this long keychain.

☆ Herschel Walker had ties to two charities that appear to have engaged in little, if any charity
▼ + stars: | 2022-12-05 | by ( Hanna Kang | ) www.businessinsider.com time to read: +11 min

He was also featured in marketing material for the Livio Cares Foundation and was listed as a Livio Cares Partner. However, there is no evidence Livio Cares engaged in philanthropic activities. According to ProPublica's Nonprofit Explorer, Walker was listed as the director of VMP Nutrition Foundation in Fort Worth, Texas. According to the Texas Comptroller of Public Accounts website, the right to transact business in Texas for VMP Nutrition as well as VMP Nutrition Foundation is listed as "forfeited." In 2017, VMP Nutrition and its founder Rodriguez settled a lawsuit filed by Southside Bank for an alleged failure to repay a $2,795,534 lien.

☆ How the founder of SiriusXM wants to tackle an organ shortage with 3D-printed hearts and lungs
▼ + stars: | 2022-11-30 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +5 min

She is the CEO of the $12 billion biotech United Therapeutics and founder of SiriusXM. Her company, the $12 billion Maryland-based biotech United Therapeutics, has already put gene-edited pig hearts, lungs, and kidneys into humans in clinical studies. Rothblatt previously founded SiriusXM before starting United TherapeuticsUnited TherapeuticsThe organ research is far from the first moonshot in Rothblatt's career. After that compound's owner, the pharma giant GSK, declined to test it against PAH, Rothblatt founded United Therapeutics in 1996 and bought the rights to the molecule. That drug helped save Jenesis, and United Therapeutics now sells a suite of PAH treatments that have helped over 12,000 patients.

☆ Billionaires like Elon Musk want to save civilization by having tons of genetically superior kids. Inside the movement to take 'control of human evolution.'
▼ + stars: | 2022-11-17 | by ( Julia Black | ) www.businessinsider.com time to read: +40 min

"We are the Underground Railroad of 'Gattaca' babies and people who want to do genetic stuff with their kids," Malcolm told me. Ellison, meanwhile, who has two children in their 30s, has reportedly resumed having kids — with his 31-year-old girlfriend. "The person of this subculture really sees the pathway to immortality as being through having children," Simone said. The person of this subculture really sees the pathway to immortality as being through having children. Before she met Malcolm, Simone was convinced she wanted to live her life single and child-free.

☆ I'm a leg-lengthening surgeon. Most of my clients are men with confidence issues — here's what the procedure's like and why I do it.
▼ + stars: | 2022-11-02 | by ( Natalie Rahhal | ) www.businessinsider.com time to read: +14 min

The only field in medicine that uses all of these tools is orthopedic surgery, so it seemed like the right fit. I specialized in limb-lengthening surgery specifically because I wanted to do something that was different from everybody else. People that undergo limb-lengthening surgery are from all walks of life, and many used COVID lockdowns to recover post-surgery. I would say 80% to 85% of my cosmetic limb-lengthening patients are men and 15% to 20% are women. Even though I've done limb-lengthening surgeries hundreds of times, I still get a little nervous.

A decade ago, CAR T cell therapy changed the world of cancer treatment, offering a personalized approach to patients with blood cancers like leukemia. A novel approach to CAR T (chimeric antigen receptor T cell) therapy aims to cut down that turnaround time significantly. Instead of reprogramming each patient's cells, researchers are testing the safety of using universal, or "off the shelf," CAR T cells from other patients, preprogrammed to fight cancer. Scientists at University College London in the United Kingdom tested the safety of the experimental approach in six children — mostly toddlers — with advanced leukemia. One particular side effect associated with CAR T therapy is called a cytokine storm, and it can be deadly.

☆ Opinion | Science Has a Nasty Photoshopping Problem
▼ + stars: | 2022-10-29 | by ( Elisabeth Bik | ) www.nytimes.com time to read: +14 min

One evening in January 2014, I sat at my computer at home, sifting through scientific papers. Manipulated imagery in scientific papers can look ordinary at first glance. However, this ability, combined with my — what some might call obsessive — personality, helped me when hunting duplications in scientific images by eye. So when a scientist’s research shows a negative result, cheating can be tempting. Legitimate criticism of scientific research should receive legal protection.

☆ About 17 Americans die waiting for transplants each day. Scientists are trying to make more organs in 5 creative ways.
▼ + stars: | 2022-10-18 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +11 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute. Hanna started a company called Renewal Bio to pursue the possibility of turning stem cells into organs for transplants.

☆ In a novel experiment, brain-like human tissue implanted in rat brains influenced the rodents' behavior
▼ + stars: | 2022-10-12 | by ( Aria Bendix | Aria Bendix Is The Breaking Health Reporter For Nbc News Digital. | ) www.nbcnews.com time to read: +6 min

Their results, published Wednesday in the journal Nature, showed that the brain-like human tissue integrated with the rat tissue, then continued to mature. The researchers injected the human tissue into the rats’ somatosensory cortexes — regions that receive and process sensory information like touch or pain. The researchers also used a puff of air to prod the rats’ whiskers, then observed how the human neurons responded. "We found that human neurons respond very quickly after we stimulated the whiskers. "Human neurons become part of the rat circuitry," Pașca said, adding that the neurons were "sparkling with electrical activity" under a microscope.

☆ 5 cutting-edge medical experiments could expand our organ supply, from gene-edited pigs to artificial embryos
▼ + stars: | 2022-09-24 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +10 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." While much of the shortage is driven by imperfect logistics and bureaucracy rather than supply, cutting-edge research could make organs — human, pig, or synthetic — more accessible in Graham's lifetime. If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute.

☆ What happens when you don't get enough sleep? Blood samples show heart risks.
▼ + stars: | 2022-09-21 | by ( Linda Carroll | Linda Carroll Is A Regular Health Contributor To Nbc News | Reuters Health. She Is Coauthor Of | ) www.nbcnews.com time to read: +6 min

“In subjects who had undergone sleep restriction, the number of immune cells circulating in the blood was higher. To look at the impact of restricted sleep on the immune system, Swirski and his colleagues conducted experiments in humans and in mice. Once again, the researchers drew blood samples and totaled the number of immune cells. Moreover, the stem cells that give birth to immune cells had changed as a result of the six weeks of shortened sleep. Those marks on the stem cells, through a series of steps, eventually lead to less diversity among the immune cells.

☆ We went inside the lab at Vertex, a company that dodged the market downturn to become one of the best-performing biotechs of 2022
▼ + stars: | 2022-09-21 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +10 min

A mosaic of human cells inside Vertex Pharmaceuticals' cell and gene-therapy laboratory. The four-story, 267,000-square-foot space is home to Vertex's cell and gene-therapy unit, with about 375 people now residing in the modern-industrial building. That has led to going after unrelated diseases like sickle cell, diabetes, muscular dystrophy, kidney disease, and pain. For instance, Vertex's approach to sickle cell is led by its CRISPR gene-editing program. Vertex PharmaceuticalsThe next test of Vertex's strategy will be an experimental treatment called exa-cel, its CRISPR gene-editing program for sickle cell.

☆ How a 34-year-old CEO and cancer survivor sets clear boundaries at work: ‘After 7 p.m., you're not allowed to Slack or email’
▼ + stars: | 2022-09-20 | by ( Gili Malinsky | ) www.cnbc.com time to read: +3 min

"I didn't sleep for years," she says about her previous attitude toward work, realizing she'd been pushing herself "to the physical edge." Even as an entrepreneur, Shuster-Bier has set clear boundaries between work and the rest of her life. "Some people love to work on Sunday at three for a few hours to clear out their email, to get ahead for the week," Shuster-Bier says, and she respects that. As a one-time policy, she gave each Alula employee an extra week off in May. 'Next week, you're taking the week off, you're working'

☆ The Ayahuasca Diaries
▼ + stars: | 2022-06-26 | by ( Mattathias Schwartz | ) www.businessinsider.com time to read: +37 min

But please understand: I didn't drink ayahuasca so I could write an article about it. I wrote an article about it so I could drink ayahuasca. I was desperate to drink ayahuasca — I had been for several months, in fact — and the formality of an assignment would help me out at home. Instead, a friend of a friend linked me up with an ayahuasca sangha, a Buddhist word for a spiritual community. I thought of my old friend, Scott, who, many years before, had declined an opportunity to drink ayahuasca.

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