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Iovance Biotherapeutics ' star asset could propel its stock to new heights, according to Goldman Sachs. IOVA YTD mountain IOVA YTD chart Iovance specializes in developing autologous tumor-infiltrating lymphocyte, or TIL, therapies for solid tumor cancers using its lead asset lifileucel. As a catalyst, analyst Andrea Tan pointed to the upcoming approval of the company's first such treatment, which is slated to be reviewed by February 2024. "With accelerated approval, lifileucel would be the first cell therapy approved for solid tumors and IOVA is preparing for commercial launch," she wrote. The analyst added that lifileucel, a "best-in-class therapy," has the potential to become the standard of care in treating melanoma.
Persons: Iovance Biotherapeutics, Goldman Sachs, Andrea Tan, Tan, CNBC's Michael Bloom Locations: Friday's
NEW YORK (AP) — George “Funky” Brown, the co-founder and longtime drummer of Kool & The Gang who helped write such hits as “Too Hot,” “Ladies Night,” “Joanna” and the party favorite “Celebration,” died Thursday in Los Angeles at age 74. Brown died after a battle with cancer, according to a statement released by Universal Music. He had retired earlier in the year, nearly 60 years after the band began, and revealed that he was diagnosed with stage 4 lung cancer. In 2023, Brown produced the band's latest album, “People Just Wanna Have Fun,” and released his memoir “Too Hot: Kool & The Gang & Me.”Political Cartoons View All 1253 ImagesHe is survived by his wife, Hanh Brown, and his five children. In lieu of flowers, his family has asked that donations can be made in his honor to the Lung Cancer Society of America.
Persons: — George “ Funky ” Brown, , Joanna ”, Brown, Robert “ Kool ” Bell, Ronald Bell, Charles Smith, Hanh Brown Organizations: Kool, The, Universal Music, Lung Cancer Society of America Locations: Los Angeles
George Brown, a founding member and drummer of the group Kool & the Gang, who played on funk, disco and pop hits that featured prominently in movies and have been sampled numerous times, died on Thursday in Long Beach, Calif. His death, at a hospital, was confirmed in a statement by the band’s publicist, who said the cause was cancer. Mr. Brown had said publicly that he had lung cancer. Mr. Brown, known as Funky, was a key contributor to several of the band’s biggest hits, including “Ladies Night,” “Jungle Boogie” and the party anthem “Celebration.”In a July interview with NPR, he described Kool & the Gang as “the sound of happiness.”In 1964, Mr. Brown linked up with Ricky Westfield and the brothers Ronald Khalis Bell and Robert “Kool” Bell, as well as other friends — Spike Mickens, Dennis “Dee Tee” Thomas and Charles Smith — to form a band that would combine jazz, funk, disco and R&B and create some of the most memorable pop songs of their era.
Persons: George Brown, Brown, . Brown, , Ricky Westfield, Ronald Khalis Bell, Robert “ Kool ” Bell, — Spike Mickens, Dennis “ Dee Tee ” Thomas, Charles Smith — Organizations: NPR, Mr Locations: Long Beach, Calif
Background: The life expectancy gap has substantially widened — and shrunk — before. At the turn of the 20th century, women had a life expectancy just two years higher than men, Dr. Yan said. That year, the life expectancy for men was 76.3 years, while for women it was 78.1. Between 2019 and 2021, the life expectancy in the United States dropped from around 79 to 76 years. Unintentional injuries — mostly drug overdoses — contributed to more than 30 percent of the life expectancy gap between men and women.
Persons: Yan, Covid, , ” Dr Locations: United States
A rapid transition to green energy sources would prevent a lot of disability and early death, researchers say. In the year 2050 alone, the transition's impact amounts to 181 million future years of healthy human life, a new report found. Add to that list 181 million years of healthy human life — annually. Mohammad Ponir Hossain/ReutersDisability-adjusted life years, or DALYs, capture years of life affected by disability and years lost to premature death. If the world rapidly transitions to renewables, they found, the energy system will still hurt human health enough in 2050 to lead to early death and disability that affects 30 million years of human life.
Persons: Martin Meissner, it's, Stephanie Roe, WWF's, Mohammad Ponir Hossain, Nick Oxford, Dylan Martinez, Jonathan Buonocore, Buonocore, Lyu, Roe Organizations: Service, Wildlife Fund, Boston Consulting, Reuters, American Lung Association . Mines, Harvard, Boston University School of Public Health, WWF, China News Service, Getty, International Energy Agency, Stanford Locations: Haltern, Germany, Dhaka, Bangladesh, Texas, Fujian Province, China
Mel Sembler, a gregarious developer and major Republican fund-raiser whose largess was repaid with prize ambassadorships by two presidents, and who founded a controversy-courting “tough love” drug rehabilitation program, died on Oct. 31 at his home in St. Petersburg, Fla. Mr. Sembler, who developed more than 350 shopping centers and other retail projects in the Southeast, was a sought-after fund-raiser for Republicans, capable of shaking the money tree for $11 million at a single dinner. establishment who had an open lane to power in the era before the rise of Donald J. Trump. Mr. Sembler was candid about the role of money in politics. “Money gives you a voice,” he told The Tampa Bay Times in 2019.
Persons: Mel Sembler, Brent, Sembler, Donald J, Trump, Dick Cheney, Newt Gingrich, Mitt Romney, Bush, , Organizations: Republican, Tampa Bay Times, , acme, Supreme, Citizens Locations: St . Petersburg, Fla
Lung cancer: Causes, symptoms and treatments
  + stars: | 2023-11-02 | by ( Katia Hetter | ) edition.cnn.com   time to read: +8 min
CNN —The American Cancer Society has just updated their lung cancer screening guidelines in an effort to increase earlier detection. In women, breast cancer is more common than lung cancer, and in men, prostate cancer is more common than lung cancer. The American Cancer Society estimates that in 2023, there will be about 238,000 cases of lung cancer, and about 127,000 people will die from lung cancer. Wen: There are two main types of lung cancers, small-cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Those with first-degree relatives with lung cancer may also have a slightly higher risk of lung cancer themselves, though often this is hard to separate from the effect of second-hand smoke.
Persons: Leana Wen, Wen Organizations: CNN, American Cancer Society, George Washington University Milken Institute School of Public Health, US Centers for Disease Control, Getty, American Lung Association Locations: United States
casey newtonAnd this caused a big sort of emotional reaction that said, wow, that feels like really, really icky. It’s just really, really awful. How do I get really, really good at this? But we have that explosion at the beginning, which is really, really exciting. I’m still interested in smartphones because I think they’re really, really advanced pieces of tech.
Persons: kevin roose, Kevin Roose, ” casey newton, Casey Newton, ” kevin roose, casey newton Oh, casey newton, ” kevin roose You’re, kevin roose That’s, kevin roose I’m Kevin Russo, Marques Brownlee, a.k.a, We’ve, don’t, casey newton Well, Meta, It’s, casey newton Right, casey newton It’s, kevin roose Totally, I’ve, you’re, Instagram, Snapchat, TikTok, They’re, that’s, kevin roose Casey, Hansel, Gretel, let’s, they’re, casey newton Jewel, , Juul, Meta didn’t, we’ve, “ We’re, There’s, Al Capone, They’ve, , Kevin, casey newton I’ve, casey newton That’s, Marquez Brownlee, Casey, He’s, Marquez, he’s, Elon Musk, Sundar Pichai, you’ll, marquez brownlee, casey newton I’m, You’ve, casey newton Let’s, you’ve, it’s, I’m, he’ll, kevin roose Marquez, PewDiePie, marquez brownlee I’ll, they’ve, Ralph, That’s, kevin roose It’s, you’d, we’re, I’d, casey newton Libraries ! marquez brownlee, everyone’s, Samantha, Davis, Fancy, Bard, DALL, Midjourney, ChatGPT, Bing, who’s, it’ll, OpenAI, Pope, kevin roose Pope, — casey newton, casey newton Ah, Mickey Mouse, Eli Lilly, barbecuing, bro, Fabio, Getty, Greg Rutkowski, kevin roose Really, Greg, there’s, Ben Zhao, casey newton We’re, Bob Ross Organizations: The New York Times, YouTube, Meta, pharma, AGs, Netflix, COPPA, Facebook, Congress, Digital Services, Federal Communications Commission, ABC, CBS, FCC, Samsung, casey newton Libraries, VR, Apple, ChatGPT, Enterprise, DALL, Disney, Twitter, Getty, “ MIT Tech, University of Chicago, Adobe Locations: California, Colorado, what’s, you’re, Europe, United States, China, earbuds
The company paid a dividend of $1.74 per share in late September, which included a quarterly base dividend of 50 cents per share and a variable dividend of $1.24. The acquisition, anticipated to close in January 2024, is expected to boost CIVI's free cash flow per share by 5% in 2024. In September, the company announced a quarterly dividend of 57 cents per share, payable on Nov. 1. (See Chesapeake Insider Trading Activity on TipRanks)EOG ResourcesLet's look at another energy company: EOG Resources (EOG). Based on this quarterly dividend, the annual dividend rate comes to $3.30 per share, bringing the dividend yield to 2.5%.
Persons: Paresh Dave, Wall, Civitas, Lloyd Byrne, CIVI, Byrne, TipRanks, Bristol Myers, BMY, Goldman Sachs, Chris Shibutani, Shibutani, Umang Choudhary, Choudhary, EOG, Nitin Kumar, Eagle, Kumar Organizations: Cisco Systems Inc, Civitas, Civitas Resources, Vencer Energy, Jefferies, Midland, Bristol, Bristol Myers Squibb, Mirati Therapeutics, Chesapeake Energy, Management, Chesapeake, EOG, Eagle Ford, TipRanks, Cisco Locations: San Jose , California, Denver, Midland, West Texas
Risky biotech M&A therapy will heal more fractures
  + stars: | 2023-10-19 | by ( Jonathan Guilford | ) www.reuters.com   time to read: +8 min
NEW YORK, Oct 19 (Reuters Breakingviews) - How can a suitor offering $1 billion see eye-to-eye with a seller asking for $2 billion? Such contingent value rights, or CVRs, are a way to get around the inherent uncertainty of an unproven drug. Its $74 billion takeover of Celgene in 2019 included a $6.4 billion payout dependent on a trio of drug approvals. There have been only 27 biotech market debuts this year, raising $2.2 billion, according to LSEG data. Given the nagging fissures in valuation perspectives, however, more dealmakers are apt to try this risky M&A therapy.
Persons: Schulman, Sidley, Bristol Myers, Myers, CVRs, Andrew Weisenfeld, IPOs, , Dan Lepanto, biopharma, Eli Lilly’s, Bristol Myers Squibb, Jeffrey Goldfarb, Sharon Lam, Streisand Neto Organizations: Reuters, Dow, Marion Laboratories, LyondellBasell Industries, Mirati Therapeutics, JPMorgan, Sanofi, Health Partners, Nasdaq Biotechnology, Reuters Graphics Reuters, Reuters Graphics, Leerink Partners, Therapeutics, Public, Bristol Myers, U.S . Food, Drug Administration, Thomson Locations: Celgene, Genzyme, U.S
LOS ANGELES (AP) — Burt Young, the Oscar-nominated actor who played Paulie, the rough-hewn, mumbling-and-grumbling best friend, corner-man and brother-in-law to Sylvester Stallone in the “Rocky” franchise, has died. Young had roles in acclaimed films and television shows including “Chinatown,” “Once Upon a Time in America" and “The Sopranos.”But he was always best known for playing Paulie Pennino in six “Rocky” movies. The short, paunchy, balding Young was the sort of actor who always seemed to play middle-aged no matter his age. It won three, including best picture. In 1985's “Rocky IV” he reprograms a robot Rocky gives him into a sexy-voiced servant who dotes on him.
Persons: — Burt Young, Oscar, Paulie, Sylvester Stallone, Young, Anne Morea Steingieser, Paulie Pennino, Rocky, balding Young, , packer, Adrian, Talia Shire, Rocky Balboa, Stallone, Rocky ”, Burgess Meredith, Jason Robards, IV, dotes, ” Young, , Lee Strasberg, Jack Nicholson's, Jake Gittes, Sergio Leone's, Robert De Niro, Rodney Dangerfield, Jennifer Jason Leigh, Bobby Baccalieri, Gloria, Robert Organizations: ANGELES, New York Times, Instagram, Marine Corps, Actors, Miami Locations: Los Angeles, America, Philadelphia, , Queens , New York, Brooklyn
A company logo is seen at the AstraZeneca site in Macclesfield, Britain, May 11, 2021. REUTERS/Phil Noble/File Photo Acquire Licensing RightsOct 18 (Reuters) - Shares in AstraZeneca (AZN.L) fell more than 4% on Wednesday after the publication of an abstract on its experimental precision drug's use in lung cancer in a late-stage trial disappointed some analysts. The abstract was published ahead the European Society for Medical Oncology's (ESMO) congress that kicks off in Madrid on Friday. By 1219 GMT, AstraZeneca shares were dwon 3.7% in London, while the broader STOXX Health Care (.SXDP)index was off 1%. Reporting by Danilo Masoni and Maggie FickOur Standards: The Thomson Reuters Trust Principles.
Persons: Phil Noble, Danilo Masoni, Maggie Fick Organizations: AstraZeneca, REUTERS, European Society for Medical, Thomson Locations: Macclesfield, Britain, Madrid, London
REUTERS/Phil Noble/File Photo Acquire Licensing RightsOct 18 (Reuters) - Shares in AstraZeneca (AZN.L) fell more than 4% on Wednesday after a data abstract on its experimental precision drug's use in lung cancer patients in a late-stage trial disappointed some analysts. Fernandez added that progression-free survival in lung cancer patients came in below expectations. Barclays analyst Emily Field also said in a note that safety looked better than expected for lung cancer patients and the data abstracts were "collectively positive" for AstraZeneca. London-listed shares of AstraZeneca were down 3.7% at 1219 GMT, while the broader STOXX Health Care (.SXDP) index was off 1%. Shares of AstraZeneca's Japanese partner Daiichi Sankyo (4568.T), which is jointly developing the cancer drug, closed 4.6% lower on Tuesday.
Persons: Phil Noble, datopotamab deruxtecan, Jefferies, Stephen Barker, Barker, Seamus Fernandez, Fernandez, Emily Field, GSK's, Danilo Masoni, Maggie Fick, Bhanvi, Shinjini Organizations: AstraZeneca, REUTERS, European Society for Medical, Friday, Guggeinheim, Barclays, AstraZeneca ., Thomson Locations: Macclesfield, Britain, Madrid, AstraZeneca . London, U.S, Milan, London, Bengaluru
REUTERS/Dado Ruvic/Illustration/File Photo Acquire Licensing RightsOct 8 (Reuters) - Bristol-Myers Squibb (BMY.N) on Sunday said it will acquire cancer drugmaker Mirati Therapeutics (MRTX.O) for up to $5.8 billion, diversifying its oncology business and adding drugs it hopes can help offset expected lost revenue from patent expirations later this decade. Bristol will pick up Mirati's portfolio drugs that target the genetic drivers of specific cancers including its lung cancer drug, Krazati, which was approved in December. The company said that it will buy Mirati for $58 per share in cash, or around $4.8 billion. Mirati has around $1.1 billion in cash on hand, so "we're paying essentially $3.7 billion enterprise value...we think with that we've gotten a very attractive deal," Lenkowsky said. Last year, Bristol acquired drug developer Turning Point Therapeutics for $4.1 billion in cash to help bolster its arsenal of cancer drugs.
Persons: Bristol Myers, Dado Ruvic, Adam Lenkowsky, Mirati, we've, Lenkowsky, Chris Boerner, Giovanni Caforio, Boerner, Lavanya Ahire, Lisa Shumaker, Diane Craft, Andrea Ricci, Michael Perry Organizations: Bristol, Bristol Myers Squibb, REUTERS, Myers Squibb, Therapeutics, U.S . Food, Drug Administration, Bristol Myers, Thomson Locations: Bristol, U.S, New York
An Exxon gas station sign is seen on October 06, 2023 in the Brooklyn borough of New York City. The Wall Street firm said the software stock is at an attractive entry point after its recent pullback. Exxon Mobil , Chevron , Occidental Petroleum — Energy stocks popped as oil prices rallied following the Hamas attack on Israel over the weekend. Blue Owl Capital — Shares of the investment company dropped 2.6% after Oppenheimer downgraded Blue Owl Capital to perform from outperform. Lockheed Martin — The aerospace and defense company saw shares rise about 4.5% in premarket trading following the surprise attack on Israel by Palestinian militant group Hamas over the weekend.
Persons: Walt, Nelson Peltz's, Trian's, Trian, Saket Kalia, Oppenheimer, Bristol Myers, Tesla, Lockheed Martin, — CNBC's Brian Evans, Lisa Kailai Han, Fred Imbert, Hakyung Kim, Yun Li, Tanaya Macheel, Pia Singh Organizations: Exxon, Walt Disney —, Street Journal, Management, JPMorgan, Spotify Technology, Barclays, Oracle, ISI, Exxon Mobil, Occidental Petroleum — Energy, Chevron, Occidental, Owl, Mirati Therapeutics, Bristol, Bristol Myers Squibb, China Passenger Car Association, Lockheed, Hamas Locations: Brooklyn, New York City, Chevron, Israel, China, Palestinian
Bristol-Myers Squibb to acquire Mirati in $5.8 billion deal
  + stars: | 2023-10-08 | by ( ) www.reuters.com   time to read: +2 min
REUTERS/Dado Ruvic/Illustration/File Photo Acquire Licensing RightsOct 8 (Reuters) - Bristol-Myers Squibb (BMY.N) on Sunday said it will acquire Mirati Therapeutics (MRTX.O) in a transaction that values the cancer drugmaker at up to $5.8 billion. The company said that it will buy Mirati for $58 per share in cash. Mirati stockholders will receive one non-tradeable contingent value right for each Mirati share held, potentially worth $12.00 per share in cash, representing an additional $1 billion of value opportunity, the company added. Bristol-Myers Squibb will finance the transaction with a combination of cash and debt, the company said in a statement. Last year, Bristol-Myers acquired drug developer Turning Point Therapeutics for $4.1 billion in cash to help bolster its arsenal of cancer drugs.
Persons: Bristol Myers, Dado Ruvic, Myers, Chris Boerner, Giovanni Caforio, Boerner, Lavanya Ahire, Lisa Shumaker, Diane Craft, Andrea Ricci Organizations: Bristol, Bristol Myers Squibb, REUTERS, Myers Squibb, Mirati Therapeutics, Bristol Myers, Therapeutics, Thomson Locations: Bristol, U.S, New York
REUTERS/Dado Ruvic/Illustration/File photo Acquire Licensing RightsOct 3 (Reuters) - The U.S. Food and Drug Administration staff reviewers said on Tuesday Amgen's (AMGN.O) late-stage study might not be sufficient to confirm the effectiveness for its lung cancer drug, as the firm pursues a traditional nod for the treatment. Amgen's drug was granted accelerated approval by the U.S. FDA in 2021 for advanced lung cancer patients with KRAS mutations whose disease has worsened after treatment with chemotherapy or other medicines. The U.S. health regulator grants the so-called accelerated approval based on data that show therapies are likely to work, and requires confirmatory trials later to give them traditional approval. Data from the study showed Lumakras reduced the risk of disease progression in patients with advanced lung cancer by 34%, compared with chemotherapy in a clinical trial. The agency is expected to make a decision on traditional approval for the drug by Dec. 24.
Persons: Dado Ruvic, Amgen's, William Blair, Matt Phipps, Lumakras, Bhanvi Satija, Shounak Dasgupta, Sherry Jacob, Phillips Organizations: REUTERS, U.S . Food, Drug Administration, U.S, FDA, Thomson Locations: U.S, Bengaluru
AstraZeneca's tozorakimab drug for chronic obstructive pulmonary disease also seems underappreciated, with a potential to reach $4.5 billion in peak sales, according to Jefferies. The firm also suggests up to $3.5 billion in sales for AstraZeneca's eplontersen , a drug aimed at treating hereditary transthyretin-mediated amyloid polyneuropathy. The pharmaceutical giant is also poised to be the frontrunner in breast cancer treatments. Another one of AstraZeneca's breast cancer therapies, also being developed with Daiichi Sankyo, came out with positive news Friday. Its experimental precision drug datopotamab deruxtecan demonstrated an improvement in slowing the progression of a common type of breast cancer in a late-stage trial.
Persons: Peter Welford, Welford, AstraZeneca's, Jefferies, AstraZeneca's eplontersen, transthyretin, deruxtecan, Pascal Soriot's, — CNBC's Michael Bloom Organizations: AstraZeneca, Jefferies, AstraZeneca's, Japan's, pharma Locations: Japan's Daiichi
ST. LOUIS (AP) — Ben Phillips’ childhood memories include basketball games with friends, and neighbors gathering in the summer shade at their St. Louis housing complex. Phillips and Deanes, 75, are co-founders of PHACTS, which stands for Pruitt-Igoe Historical Accounting, Compensation, and Truth Seeking. Their attorney, Elkin Kistner, said it would be “appropriate and necessary” for Hawley's proposal to be widened to include former Pruitt-Igoe residents. And St. Louis wasn't alone in being subjected to secretive Cold War-era testing. The area of the testing in St. Louis was described in Army documents as “a densely populated slum district.” About three-quarters of the residents were Black.
Persons: — Ben Phillips, Louis, ” Phillips, , Phillips, Chester Deanes, Pruitt, , inactions, Sen, Josh Hawley, Joe Biden, Elkin Kistner, Louis wasn't, Lisa Martino, Taylor, ” Deanes, ” Pruitt, Igoe, Deanes, Army “, Deane, Cori Bush, Organizations: LOUIS, Army, Associated Press, AP, Missouri Independent, Act, Republican U.S, Democratic, PHACTS, Democratic U.S . Rep Locations: St, Louis, , Pruitt, Deanes, Igoe, California, America
LONDON, Sept 11 (Reuters) - Data released on Monday by AstraZeneca (AZN.L) from a late-stage trial combining its blockbuster cancer drug Tagrisso with chemotherapy to treat a type of lung cancer raises the bar for Johnson & Johnson's (JNJ.N) rival treatment, analysts said. A brief summary from the Phase 3 trial, called FLAURA2, was released in May, and the detailed data was presented on Monday in Singapore at the World Conference on Lung Cancer. The FLAURA2 trial showed that when adding chemotherapy to Tagrisso, the risk of disease progression or death is reduced by 38% when compared to Tagrisso alone. "With the strong FLAURA-2 data in hand and likely included in treatment guidelines soon, the hurdle is now pretty high in our view for MARIPOSA," the UBS note read. Barclays analysts said the FLAURA2 trial data presented on Monday included doctor and patient surveys that showed a strong preference for the convenience of a single therapy compared with combinations.
Persons: Johnson, Pascal Soriot, Michel Demare, Soriot, Maggie Fick, Emelia Sithole Organizations: AstraZeneca, Lung Cancer, Barclays, UBS, Reuters, Thomson Locations: Singapore, British, MARIPOSA
CNN —The number of first responders who have died from 9/11-related illnesses now almost equals the number of firefighters who died during the terror attacks themselves. A total of 341 New York City Fire Department firefighters, paramedics and civilian support staff who died from post-911 illnesses are now memorialized at the FDNY World Trade Center Memorial Wall, according to the Uniformed Firefighters Association. The memorial commemorates both first responders who died during the attacks and those who died from related illnesses in the years since. That count almost equals the 343 New York firefighters who died during the 2001 attacks. More than 71,000 people are currently enrolled in the World Trade Center Health Registry, a long-term study seeking to understand the physical and mental health effects of the terror attacks.
Persons: , Laura Kavanagh, Joseph Brosi, Jim Brosi, , ” Joseph Brosi, Joe, Brosi Organizations: CNN, New York, New York City Fire Department, FDNY, Trade Center, Uniformed Firefighters Association, World Trade, World Trade Center Health, World Trade Center, Zero Locations: New York City
The economic claims amount is uncapped, which will permit other device users to apply for compensation. This tentative settlement, which is subject to federal court approval, does not address other significant claims in the plaintiffs’ cases involving personal injury or the cost of medical care related to use of the breathing machines. The company has faced a multiyear setback, after beginning recalls in the United States of about five million of its breathing machines, which are intended for people with sleep apnea and other maladies. The lawsuits have claimed that flaking foam and gasses emitted from the machines were linked to health issues including respiratory illnesses, lung cancer and death. The foam was used in the machines to reduce noise and vibration.
Persons: Philips Respironics, Philips Locations: United States
The Johnson & Johnson logo is displayed on a screen on the floor of the New York Stock Exchange (NYSE) in New York, U.S., May 29, 2019. REUTERS/Brendan McDermid/File Photo Acquire Licensing RightsSept 6 (Reuters) - Johnson & Johnson (JNJ.N) said on Wednesday its combination drug helped increase the duration of no progress in a type of non small-cell lung cancer in patients. J&J's therapy was tested in patients in whom the disease progressed even after they were treated with AstraZeneca's Tagrisso. J&J is also testing its combination treatment in a head-to-head study with Tagrisso, and expects data from the trial by the end of this year. If successful, the company expects the therapy to become a first-line treatment for NSCLC patients with the mutation.
Persons: Johnson, Brendan McDermid, AstraZeneca's, Rybrevant, Leroy Leo, Pooja Desai Organizations: New York Stock Exchange, REUTERS, Johnson, Thomson Locations: New York, U.S, Bengaluru
Aging in place, surrounded by familiar places, faces and memories, can provide a sense of comfort and independence. Being an aging nation also means becoming a nation of caregivers, one that requires a new system of support. For most older Americans, care will come from unpaid family members or friends, who contributed around $600 billion worth of free labor to the economy in 2021, according to AARP. Starting in the mid-1990s, he spent several years caring for his mother, who suffered from schizophrenia and lung cancer. With increasing frequency, he shuttled between his home in upstate New York and hers in South Carolina, taking her to medical appointments.
Persons: Dwane Hodges, , Organizations: AARP Locations: North Carolina, New York, South Carolina
CNN —Users of marijuana had statistically higher levels of lead and cadmium in their blood and urine than people who do not use weed, a new study found. Marijuana users also had 22% higher cadmium levels in their blood than non-users, and 18% higher levels in their urine, Sanchez said. “Our study wasn’t able to tease apart whether or not self-reported cannabis users were using medical or recreational cannabis, so we can’t say definitively if medical cannabis users specifically had higher metal levels,” she said. Heavy metals aren’t just in marijuana — tobacco smokers are exposed to even more types of toxins. While that’s good news for the environment, it’s worrisome for marijuana users.
Persons: , Tiffany Sanchez, Sanchez, Beth Cohen, ” Sanchez, can’t, Dr, Leonardo Trasande, NYU Langone, I’m Organizations: CNN, Columbia University Mailman School of Public Health, US Environmental Protection Agency . Marijuana, University of California, Environmental, National Health, Cleveland Clinic, NYU, US Department of Agriculture, District of Columbia Locations: New York City, San Francisco, Italy
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