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How to Spot Kawasaki Disease in Your Child
  + stars: | 2024-02-27 | by ( Emily Baumgaertner | ) www.nytimes.com   time to read: +1 min
Doctors across the United States are seeing a rise in Kawasaki disease, a mysterious condition that primarily affects children under 5. The illness is the most common cause of acquired heart disease in children worldwide but it is often unrecognized or misdiagnosed. Kawasaki disease is rare, but cases are climbing in the United States. Here are the important things to know about Kawasaki disease. Kawasaki disease, also known as K.D., is one of the leading pediatric mysteries.
Locations: United States
“That's pretty much when my journey started with cancer.”AdvertisementIn 2021, at the age of 34, 14 years after her abnormal bleeding first started, Grant-Noonan was diagnosed with stage three cervical cancer. Eliminating cervical cancer with vaccinesRates of cervical cancer are dropping thanks to the roll-out of vaccines in pre-teens against the human papillomavirus that causes the majority of cases, with the World Health Organization aiming to eliminate the disease by the end of the century. AdvertisementGrant-Noonan had two false negative pap smears before being diagnosed with cervical cancer. Avi-Grant-NoonanSpreading awareness of cervical cancer gives Grant-Noonan a sense of purposeOnce she was diagnosed, Grant-Noonan saw a gynecological oncologist within two weeks. Educating people about cervical cancer and how to prevent it through her involvement with Cervivor , a nonprofit network of cervical cancer survivors, has given Grant-Noonan a sense of purpose, she said.
Persons: , Avi Grant, Noonan, Grant, , ” Grant, , Noonan —, it's, weren’t, they’ve, wasn't, Noonan Grant, brachytherapy Organizations: Service, Business, World Health Organization, Disease Control, Cancer Locations: Honduras, Miami, Florida
But golden tigers — also known as golden tabby tigers or strawberry tigers — are not a subspecies: they’re the result of a genetic mutation that changes the color of their fur. Ramnarayanan spotted the golden tiger, which came within 100 meters of the group, while guiding a safari in the wildlife reserve. The big cat is one of four "golden" tigers in Kaziranga, according to the park's official social media. If Kaziranga’s tiger population becomes more isolated, issues like inbreeding will threaten the population, said Sharma in his post on X. For photographer Ramnarayanan, Kaziranga’s golden tiger was his first sighting of these unusually colored big cats.
Persons: Gaurav Ramnarayanan, Ramnarayanan, “ I’ve, , Uma Ramakrishnan, There’s, , that’s, Gaurav, Mayuresh Hendre, Rabindra Sharma, Sharma, Kota Ullas Organizations: CNN, UNESCO, Heritage, National Center for Biological Sciences, Centre for Wildlife Studies Locations: India’s, Assam, Kaziranga, Mumbai, , India
A new book “The Naked Neanderthal” says humans were the main cause thanks to their superior weapons. Compared to early humans, Neanderthals were muscular with a prominent brow and less pronounced chin. Since humans were the final species to occupy the cave, Slimak argues it's because they'd replaced those Neanderthals by wiping them out. Humans' superior weaponsScientists have found relatively few weapons belonging to Neanderthals , Slimak wrote. Yet genes can't tell us much about the nature of these interactions or how closely or amicably humans and Neanderthals lived.
Persons: Ludovic Slimak, , April Nowell, sapien, , , Slimak, Bill O'Leary, sapiens, they'd, Chemnitz State Museum of Archaeology Hendrik Schmidt, Nowell, haven't, Nikola Solic, ” Nowell, Sapiens Organizations: Service, University of Victoria, Smithsonian Museum, Washington, Getty, Chemnitz State Museum of Archaeology, Reuters Locations: Europe, East, Central Asia, Southern Siberia, Southern France, Chemnitz, France, Spain, Krapina, Croatia
The Vision Pro's scary side effect
  + stars: | 2024-02-11 | by ( Adam Rogers | ) www.businessinsider.com   time to read: +11 min
The reviews are in, and the tech press is lauding the Apple Vision Pro headset for delivering on the company's promises. Apple and Meta are hoping that this virtual world will be so compelling that you won't just visit. Apple Vision Pro AppleThese are all, as the IT people say, known issues. When people adapt to a perceptual change for long enough, the real world starts to look wrong in the opposite direction. In the meantime, while he's doing his work, maybe don't forget to take that Vision Pro off once in a while.
Persons: It's, They're, you'll, Jeremy Bailenson, You've, That's, they're, techies, Bailenson's, passthrough, Bailenson, doesn't, I've, William Gibson, We've, he's, Adam Rogers Organizations: Apple, Meta, Stanford, Honda, Business
Caldwell, Idaho CNN —Jen and John Adkins never expected to have to send a package like this. Idaho’s abortion laws meant they had to seek care across state lines after receiving devastating news about a much-wanted pregnancy. “As soon as that ultrasound technician put that wand on my stomach and I saw the baby on the screen, I knew something was wrong,” Jen told CNN. “I was sent home to grieve and mourn and call around to see if we could get an appointment out of state,” Jen said. The move, he said, was for personal reasons: “Boise is a wonderful place in general,” he told CNN via email.
Persons: Idaho CNN — Jen, John Adkins, Jen, John, Julie Lyons, who’s, , ” Lyons, Jennifer, Jennifer Adkins, they’d, ” Jen, , , Turner, , ’ ” Jen, Jennifer Adkins ‘, Roe, Wade, wasn’t, that’s, ” John, Jen Adkins, Barton Bishoff, ’ It’s, Lyons, Raul Labrador, Dr, Thomas Lee, Lee, , he’d “, Sanjay Gupta Organizations: Idaho CNN, FedEx, CNN, Research, US, Walgreens, Bureau of Labor Statistics, Center for Reproductive Rights, Defense, CNN Health Locations: Caldwell, Idaho, Caldwell , Idaho, Boise, Portland , Oregon, Hailey, Sun Valley, Portland, St, Luke’s, Oregon
“Xist is a very long RNA, 17,000 nucleotides long, or letters, and it associates with approximately almost 100 proteins,” Chang said. Chang wondered whether the clumps of protein molecules that arise when Xist connects with the X chromosome were a trigger for autoimmune disease. The experiments weren’t designed to show whether Xist or the related proteins cause autoimmune disease in the animals. The samples from patients with autoimmune disease produced higher levels of autoantibodies in reaction to proteins associated with Xist, the researchers found. Plus, environmental factors play a big role in autoimmune disease.
Persons: Howard Chang, Chang, , it’s, Montserrat Anguera, ” Anguera, wasn’t, ” Chang, “ It’s, Organizations: CNN, Stanford University, Cell, Stanford School of Medicine, University of Pennsylvania School of Veterinary Medicine Locations: United States, Montserrat
Still, the question remains: Does cannabis truly cause psychosis and related diseases such as schizophrenia — or is this another overblown claim? It is especially important for us, as doctors, to untangle whether cannabis actually causes psychosis. Still, of all the drugs associated with this uncommon kind of psychosis, cannabis is the most common culprit. CBD products should only be purchased from reputable companies that test their products through independent labs and share the results. We shouldn’t jump to the conclusion that cannabis causes psychosis, but anyone who plans to use cannabis should know their personal risk factors and exercise caution accordingly.
Persons: David L, Peter Grinspoon, David Nathan Eli Nathan Dr, we’ve Organizations: Drug Policy, Harvard Medical School, Marijuana, Drug, CNN, Street Journal, US Food and Drug Administration Locations: hyperbolically
Increasingly, people are interested in pursuing how their genes may be affecting their health, nutrition, fitness potential and risk of injury. The global market for these direct-to-consumer genetic tests is projected to soar in the next several years, skyrocketing from $1.9 billion in 2023 to $8.8 billion by 2030, according to a market analysis report by Grand View Research. Still, some are intriguedDespite these issues, many remain intrigued by DNA fitness tests. Balance Gym recently partnered with FitnessGenes, a UK-based company that sells genetic tests, to help its clients achieve better results from their workouts. Time, and further scientific advances, may shed more light on whether DNA fitness tests are, or can be, useful.
Persons: they’re, there’s, Timothy Caulfield, “ I’ve, ” Caulfield, Caulfield, , Eva, Dylan MacKay, ” MacKay, , Devin Maier, Maier, ” Maier, MacKay, Melanie Radzicki McManus Organizations: CNN’s, CNN, Grand View Research, Indian, Australia’s National Rugby League, University of Alberta, University of Manitoba, FitnessGenes Locations: Europe, Orthopaedics, Uzbekistan, China, Edmonton, Winnipeg , Canada, Washington ,,
WASHINGTON (AP) — Women are far more likely than men to get autoimmune diseases, when an out-of-whack immune system attacks their own bodies — and new research may finally explain why. One theory is that the X chromosome might be a culprit. The X chromosome is packed with hundreds of genes, far more than males’ much smaller Y chromosome. Every female cell must switch off one of its X chromosome copies, to avoid getting a toxic double dose of all those genes. “We think that’s really important, for Xist RNA to leak out of the cell to where the immune system gets to see it.
Persons: , John Wherry, wasn’t, Howard Chang, Chang, ” Chang, Epstein, Barr, Chang’s, Xist, hadn't, Penn’s, they’re, Stanford’s Chang Organizations: WASHINGTON, Stanford University, University of Pennsylvania, Howard Hughes Medical Institute, Associated Press ’ Health, Science Department, Associated Press Health, Howard Hughes Medical Institute’s Science, Educational Media Group, AP
Walnut, a white-naped crane and internet celebrity, has passed away at age 42. That preference continued when she came to the institute; she showed no interest in breeding and even attacked male crane suitors. Photos You Should See View All 45 ImagesBut white-naped cranes are considered vulnerable by the International Union for Conservation of Nature. And as the offspring of two wild-caught cranes, Walnut’s genes were not represented in U.S. zoos. Once Crowe had gained her trust, he was able to artificially inseminate her using sperm from a male crane.
Persons: Chris Crowe, Walnut, ” Crowe, “ I’ll, Chris, Crowe Organizations: WASHINGTON, Conservation Biology Institute, National Zoo, International Crane Foundation, International Union for Conservation of Nature . Locations: Front Royal , Virginia, U.S, Mongolia, Siberia, Korea, Japan, China, Wisconsin
But if he were born today with access to gene therapy for spinal muscular atrophy, he might have been able to walk without assistance. He might have been able to live a life without fear of impending medical catastrophe. The way Mr. Parish sees it, the life he has lived will one day become something of a historical curiosity. His experience of S.M.A., with all the suffering it has entailed, will likely be rendered extinct. Gene therapy has seen remarkable and highly publicized success in recent months, from the Food and Drug Administration’s approval of what amounts to cures for sickle cell disease to the news that a boy with congenital deafness could hear for the first time in his life following gene therapy.
Persons: Tyler Parish, Parish Organizations: Food Locations: Boston
The need for more transplant organs is immense and growing. Researchers have transplanted genetically modified pig kidneys and hearts into people who were brain-dead to test whether they work in humans. Although Larry Faucette was too sick for a human heart transplant, University of Maryland doctors said he seemed physically strong enough for a genetically modified pig heart. It was more than a decade after the first heart transplant but long before such procedures became relatively routine. “We learned that the pig heart is an adequate substitute for a human heart.
Persons: Lawrence Faucette, Ann, he’d, ” Ann, Larry Faucette, Ann Faucette Ann, Larry, didn’t, , Robert Montgomery, , Shelby Lum, ” Montgomery, Xenotransplantation, Art Caplan, Caplan, Babe ”, ” Caplan, They’re, eGenesis, people’s, Dr, Mike Curtis, Sanjay Gupta, ” Curtis, hasn’t, Julie O’Hara, Jim Parsons, Jayme Locke, couldn’t, Locke, Parsons, NYU —, Montgomery —, O’Hara, ” Locke, David Bennett Sr, Mary, David Jr, Bartley Griffith, Bennett, they’ve, Muhammad M, Mohiuddin, Larry Faucette’s, David Bennett’s, ” Griffith, xenotransplantation Ann Faucette, Wilbur, White’s, Ann Faucette, NYU ethicist Caplan, they’re, NYU’s Montgomery, UAB’s Locke, Steve Wood, ’ Curtis, “ I’m, it’s, ” O’Hara, Bennett’s, Larry Faucette —, ” Bennett’s, Faucette, who’d, Griffith, would’ve, Kate, Lucy, Nadia Kounang Organizations: CNN, Food and Drug Administration, University of Maryland, FDA, National Institute of Allergy, NYU Langone Transplant Institute, NYU Langone's Transplant, NYU Grossman School, Medicine’s Department of Population Health, “ Disney, University of Alabama, Transplant Institute, Parsons Family, Birmingham, NYU, University of Maryland School of Medicine, Doctors, University of Maryland Medical Center, Uno, UAB, CNN Health, NFL Locations: Frederick , Maryland, United States, Montgomery, , Midwest, Yucatan, Maryland
Scientists based in Australia have found that mouse-sized male antechinus trade sleep to leave more time for reproductive activities during mating season, with one male who was monitored halving his sleep time during that period. Non-breeding dusky antechinus spend an average of 15.3 hours of the day asleep, according to the researchers. “Sleep restriction in breeding male antechinus is likely to be an adaptive behavioral response driven by strong sexual selection,” the paper said. To study the semelparous marsupials, researchers examined two antechinus species: dusky antechinus (Antechinus swainsonii) and wild agile antechinus (Antechinus agilis) both captive and wild. Lesku said researchers would next like to examine how male antechinus deal with restricting their sleep for three weeks.
Persons: ” Erika Zaid, , Erika Zaid, Francesca Leonard, Zaid, John Lesku, antechinus, ” Lesku, Erika Zaid “, Volker Sommer, ” Sommer, Lesku Organizations: CNN, La Trobe University, , University College London Locations: Australia, Melbourne
Gene therapy has allowed several children born with inherited deafness to hear. Globally, 34 million children have deafness or hearing loss, and genes are responsible for up to 60% of cases. Hereditary deafness is the latest condition scientists are targeting with gene therapy, which is already approved to treat illnesses such as sickle cell disease and severe hemophilia. Also, some people consider gene therapy for deafness ethically problematic. "This is real proof showing gene therapy is working,” Chen said.
Persons: , Zheng, Yi Chen, Dr, Yilai Shu, Chen, Eli Lilly, Akouos, he's, John Germiller, ” Germiller, , Lawrence Lustig, Teresa Blankmeyer Burke, ” Chen Organizations: Children's Hospital of Philadelphia, Fudan University, Shanghai Refreshgene Therapeutics, Regeneron Pharmaceuticals, Decibel Therapeutics, Columbia, Gallaudet University, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: China, Shanghai, Philadelphia, Spain
People under 50 in the US are dying from colorectal cancer at an increasing rate. AdvertisementMore people under the age of 50 are dying of colorectal cancer than ever before, according to the American Cancer Association. The disease is sometimes called colon cancer or rectal cancer, depending on where it starts. When colorectal cancer is caught early, before it has spread, the chance a person will live for another five years is about 90%. AdvertisementShe now visits her gastroenterologist regularly, eats healthy, exercises, and raises awareness of the signs of colorectal cancer.
Persons: , Kimmie Ng, you've, JJ Singleton, Singleton, Lynch, Tom McKenna, Paula Chambers Raney, Doctors, gastroenterologist, Kim Schewitz, kschewitz@businessinsider.com Organizations: Service, American Cancer Association, Dana, Farber Cancer Institute, NBC Locations: Boston
Intergenerational trauma is where the psychological effects of painful events are passed on in families. A psychotherapist shared five signs you might be experiencing intergenerational trauma. Symptoms of intergenerational trauma include difficulty regulating emotions and being overly suspicious. However, a person experiencing intergenerational trauma may not be consciously aware because the symptoms may have become normalized Hammond said. AdvertisementDifficult relationships in your family follow a patternOne of the most obvious indicators of intergenerational trauma is a repeating pattern of relationship dynamics in your family, Hammond said.
Persons: , Hendrix Hammond, Hammond, don't, I'd, you've, what's Organizations: Service Locations: London
Our genetics play a big role in how easy we find it to gain and lose weight. But it's possible to be a healthy weight despite your genes, an expert in the genetics of obesity said. Don't focus on calories aloneTo lose weight, you have to be in a calorie deficit , meaning you're burning more calories than you consume. Focus on your health over your appearancePeople want to lose weight for lots of reasons but a common motivation is to fit into societal beauty ideals. This can prove to be a weak motivator in the long run though, and doesn't necessarily benefit your health, Yeo said.
Persons: , it's, Giles Yeo, Yeo, you've Organizations: Service, University of Cambridge Institute of Metabolic, US News, Research
Spirit Airlines , JetBlue Airways — The airline stocks slid after a federal judge blocked JetBlue Airways' proposed $3.8 billion acquisition of Spirit Airlines. JetBlue shares fell nearly 1%, while Spirit Airlines dropped more than 20%. SolarEdge Technologies — The solar stock fell 5% following a downgrade by Barclays to underweight from equal weight. Twist Bioscience — Shares climbed 3.2% on the heels of an upgrade to buy from neutral at Goldman Sachs. Ford — Shares shed 2.3% on the back of a UBS downgrade to neutral from buy.
Persons: Sinclair —, Sinclair, Goldman Sachs, Davidson, William Blair, Nutanix, Wolfe, Uber, Tesla, Morgan Stanley —, Ted Pick, Visteon, Morgan Stanley, Morgan, , Sarah Min, Yun Li, Jesse Pound, Michelle Fox Organizations: Spirit Airlines, JetBlue Airways —, JetBlue Airways, Bank of America Securities, Susquehanna Financial, JetBlue, LSEG, Diamond Sports Group, Diamond, Technologies, Barclays, Goldman, , Broadcom, VMware, Deutsche Bank, Ford —, UBS, JPMorgan, Polaris, Mattel Locations: Rivian, China
Read previewGenes that may have once helped ancient herders fight infectious parasites could contribute to autoimmune diseases today, like multiple sclerosis. For example, rates of MS are twice as high in the northwest of Europe, including in Scandinavia, compared to southern Europe. AdvertisementThey analyzed teeth and bones from Europe and Western Asia, adding to an ancient DNA database of about 1,600 genomes. Northern Europeans are also more susceptible to MS than in southern Europe, where Yamnayan ancestry is less common. AdvertisementFor some people, this inflammatory response can go overboard and start attacking the body's own cells, as with MS, Iversen said.
Persons: , it's, Rasmus Nielsen, Nielsen, Matthew Dunham NMB, immunologist Dr, Astrid Iversen, haven't, Iversen Organizations: Service, Business, University of Copenhagen, University of Cambridge, University of California, BBC Locations: Europe, Scandinavia, Western Asia, Berkeley, Northern
CNN —With her signature megawatt smile and timeless style, Julia Roberts might be a beauty icon, but she doesn’t take herself too seriously. When asked in a new interview with British Vogue what keeps her looking youthful at 56, the actor responded with a wry wit. Lachlan Bailey/Vogue‘Leading a life that is fulfilling’Jokes aside, Roberts says the key to youthfulness is in the people and experiences that make up her life. Lachlan Bailey/Vogue‘They see something familiar’That audiences find her relatable is something Roberts is acutely aware of, for better or worse. Roberts also discussed how feminism shows up in her work, nodding to her decision not to do nude scenes in films.
Persons: Julia Roberts, “ Pickling, , ” Roberts, Hill, Richard Curtis, she’s, Lachlan Bailey, Roberts, , Erin Brockovich, that’s, Curtis, Anna Scott, I’m Organizations: CNN, Vogue, Globe, Locations: Hollywood, “ Notting, cardigan,
These genetic variants may have subsequently proved beneficial to European populations in making the shift from hunting and gathering to farming. “DNA from hunter-gatherers is present at higher levels in Northeastern Europe, which means the region has an elevated genetic risk of developing Alzheimer’s disease,” Barrie said. Similarly, the ancient genetic information shed light on the evolutionary history of traits such as height and lactose tolerance. And for most traits, MS included, the genetic effects are the result of multiple genetic variants,” he said. “Ultimately, we can’t say that MS came from Bronze Age populations, but these populations’ movements and environments contribute to differences in MS risk today.”
Persons: , , Rasmus Nielsen, It’s, William Barrie, Astrid Iversen, ” Iversen, ε4, ” Barrie, Samira, Asgari, Tony Capra, Capra, wasn’t Organizations: CNN —, University of California, Danish National, University of Cambridge’s, University of Oxford, Icahn School of Medicine, Bakar Computational Health Sciences Institute Locations: Western Europe, Central Asia, Europe, Berkeley, Kazakhstan, Northeastern Europe, Mount Sinai, New York, Bakar, San Francisco
In the pharmaceutical industry, AI may one day accelerate new-drug development. In the foreseeable future, McClain expects the healthcare industry to use AI technology to design personalized medicines. Risks to considerWhile AI offers promise for the healthcare industry, there are also a variety of risks professionals using AI must consider and mitigate. Showalter said that a lack of "comprehensive regulations" can also make using AI technology in healthcare settings risky. With this in mind, he said, the medical industry must understand the "fundamentals of AI and its applications in healthcare."
Persons: , Sean McClain, McClain, Tim Showalter, Showalter, it's, Fred, haven't, Surya Josyula, Josyula Organizations: Experts, Service, Northwestern Medicine, Fred Hutchinson Cancer Center, UW Medicine, University of California, Fujitsu, Aichi Cancer, Fujitsu Laboratories of America Locations: University of California San Diego, Nagoya, Japan, China, United States
She's been greeted with hugs from strangers at the biannual convention for people with Williams syndrome, which make her "feel like a rockstar." That's common for those with Williams syndrome, said Mary Van Haneghan, the executive director of the WSA. Online environments can be difficult for people with Williams syndrome to navigate, says Joel Liestman, the director of family support at the WSA. She sees Williams syndrome as a gift and believes everyone could learn more empathy from those with the condition. He has had two relationships with women with Williams syndrome, but in both cases they didn't work out.
Persons: Tobi Akbas, he'd, Tobi, Williams, I've, Jackie Molloy, Terri, he's, Robert Boddie Jr, Boddie, Karen Levine, She's, There's, Haley Gallinger, Daren Bjerke, who's, Devin, John Martinez, Mary Van Haneghan, it's, doesn't, You've, neurotypical, Allie, Joel Liestman, That's, Callie Truelove, I'm, Jocelyn Krebs, Truelove, we're, he'll, we've, Levine, Josh Duffy, He's, Duffy, vlogs, We're, Hayley Cuccinello, Louise Ridley, Kevin Kaplan Organizations: Williams Syndrome Association, Business, Continental Village Fire Department, Tobi, Go, WSA, New York, Louise Ridley Design, Trenton Almgren Locations: Garrison , New York, Santa, Garrison, Peekskill , NY, recliners, Maine, Brunswick , Maine, labrador, New, New York City, Trenton
Orchid, a startup that tests embryos for genetic diseases, has just raised $12 million. "The way that IVF and embryo screening works today is the amount of information available is really limited," Orchid CEO and cofounder Noor Siddiqui said. Genetic testing has been around for years, but it has been usually limited in the diseases it can identify, which include cystic fibrosis, Bloomberg reported. Orchid produces reports with two types of genetic testing: monogenic and polygenic. The cost of the test depends on the number of embryos that Orchid tests.
Persons: Noor Siddiqui, Siddiqui, Orchid, Dylan, Anne Wojcicki, Fidji Simo, Peter Kraft Organizations: Business, Bloomberg, Prometheus Fund, Starbloom Capital, One Ventures, Los Angeles Times Locations: San Francisco, Pebblebed
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