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New York CNN —Bud Light Seltzer has a problem: People still think there’s beer in the spiked seltzer. “We launched Bud Light Seltzer with the Bud Light name in 2020 because it came with immediate benefits in terms of recognizability and distribution,” he said. From Bud Light Seltzer/YouTubeTo that end, Bud Light Seltzer is rolling out a new, year-long ad campaign with the slogan “100% Hard Seltzer, 0% Beer.” The debut TV spot shows a Bud Light Seltzer delivery truck rolling through a brown-colored desert with colorful bubbles floating through the back. In one ad shown during the 2020 Super Bowl, Bud Light Seltzer enlisted rapper Post Malone and showed the inside of his brain trying to decide to either buy Bud Light or Bud Light Seltzer from a convenience store. Sales of Bud Light Seltzer have fallen about 24% last year, the firm said, which is worse than the seltzer category on average, which fell nearly 15%.
A court officer removes Albert Schweitzer's handcuffs at a hearing in Hilo, Hawaii, on Jan. 24, 2023. “Nerves, anxiety, scared.”The justice system is “flawed,” he said, calling himself one of many imprisoned for crimes they didn’t commit. Some intentional and some unintentional.”Ireland’s relatives couldn’t immediately be reached for comment on the petition and Schweitzer’s release. In 2019, Schweitzer’s attorneys and Hawaii County prosecutors entered into a “conviction integrity agreement” to reinvestigate the case. Despite the lack of evidence linking them to the killing, the two Schweitzers and Pauline were indicted in 1997.
But a new survey suggests a “disturbing” lack of awareness about the Holocaust in the Netherlands, where she and her family hid for years before being discovered and deported to a Nazi concentration camp. Equally disturbing is the trend toward Holocaust denial and distortion,” Claims Conference President Gideon Taylor said in a press release accompanying the survey. Some of them, a small part, do not even know about the Holocaust,” Dutch Holocaust survivor Max Arpels Lezer, 86, told NBC News by video call from his home in Amsterdam. A memorial at the Westerbork transit camp in the Netherlands, where Dutch Jews were kept before being sent to concentration camps. In 1961, Lezer married Sofia, now 86, who as a child had been hidden by a Dutch family during the war.
But with the election behind him and a full six-year term ahead, Warnock fully embraced Biden at the service. “That, my friends, is God’s work,” said Warnock, adding that Biden “had a little something to do with it.”As Biden begins to turn his attention toward an expected 2024 reelection effort, Georgia is going to get plenty of his attention. “But at this inflection point, we know a lot of work that has to continue on economic justice civil rights, voting rights, protecting our democracy. … Are we a people who will choose democracy over autocracy? "I’ve spoken before parliaments, kings, queens, leaders of the world ... but this is intimidating,” Biden said in opening his sermon.
CIOs Nominate Their Favorite Reads of 2022
  + stars: | 2022-12-28 | by ( Tom Loftus | ) www.wsj.com   time to read: +9 min
Chief information officers, ever alert to any development in a field that only hurtles forward, largely reflected that alacrity in their choice of reading during 2022. PREVIEWChris Bedi, chief digital information officer, ServiceNow Inc. Photo: IBM Corp.Ron Guerrier, chief information officer, HP Inc. Photo: Cisco Systems Inc.Fletcher Previn, chief information officer, Cisco Systems Inc. Photo: Home Depot Inc.Fahim Siddiqui, chief information officer, Home Depot Inc.
WASHINGTON — White House officials on Thursday announced steps to provide more Covid testing, vaccinations and supplies as case numbers tick up in another winter wave of coronavirus infections. The Biden administration says it will offer more free at-home Covid tests, boost efforts to vaccinate nursing home residents and prepare supplies that can be sent to states in need. Starting Thursday, the White House will make another round of free Covid tests available by allowing households to order up to four at-home tests from Covidtest.gov. The administration official said the White House expects infections to continue to rise as more people gather indoors for holiday celebrations in the coming weeks. The senior administration official said the administration has distributed 6 million courses of Paxlovid to local communities and indicated that it is confident there will be enough supply to meet demand.
Social media users in early December 2022 have falsely claimed that Albert Bourla, the CEO of Pfizer, has resigned after allegedly saying that mRNA vaccines are unsafe and ineffective. A Pfizer spokesperson told Reuters via email, “Albert Bourla continues to serve as the chairman and CEO of Pfizer. Multiple studies have shown that mRNA vaccines are safe and effective (here), (here), (here), (here). Pfizer confirmed that CEO Albert Bourla is not resigning. Update Dec. 16, 2022: Updates headline to clarify that Albert Bourla is not resigning and did not say mRNA COVID-19 vaccines don’t work.
Research published Monday has confirmed a link between a Covid infection and a debilitating heart condition called POTS, or postural orthostatic tachycardia syndrome, that has been diagnosed in some patients with long Covid. POTS was also linked, to a lesser degree, to Covid vaccination with an mRNA vaccine, according to the new study. He also said that the link between POTS and Covid vaccination needs to be confirmed with further studies. Other vaccines have also been linked to POTS in early accounts, but further research did not establish a causal link. The link between an infection — including Covid — and POTS, however, is more well-established.
U.S. regulators on Thursday cleared doses of the updated Covid-19 vaccines for children younger than age 5. Omicron-targeted booster shots made by Moderna and Pfizer already were open to everyone 5 and older. Children under 5 who already got all three Pfizer doses aren’t yet eligible for an updated booster. “Vaccines remain the best defense against the most devastating consequences of disease caused by the currently circulating omicron variant,” FDA vaccine chief Dr. Peter Marks said in a statement. The CDC last month released the first real-world data showing that an updated booster, using either company’s version, does offer added protection to adults.
Users on social media are sharing a video of news headlines and portions of articles on COVID-19 vaccine effectiveness over time without context to question whether the vaccines ever worked. Initial clinical trials for Pfizer’s vaccine showed 95% efficacy against symptomatic COVID-19 (here) while Moderna trials showed 94% efficacy (here). CONTEXT COUNTSEarly in the viral video, headlines touting 100% efficacy refer to small trials or specific outcomes. He added that these results are not indicative of vaccine effectiveness for all groups of people, which can vary. A video of news headlines is not proof the vaccines are ineffective or a scam.
The Financial Accounting Standards Board on Wednesday said it wants companies to provide more information on their income taxes, the group’s latest attempt to give the public more detail on the companies they invest in. At least once a year, public companies have to disclose the amount of cash taxes they pay. Companies must also disclose their effective tax rate, or the ratio between their tax expense and their pretax income. The first proposal came in 2016 and would have required companies to distinguish their U.S. from their foreign income taxes, among other changes. This time, it sought a breakout of the amount of federal, state and foreign taxes public companies paid, as well as disclosure on a quarterly basis.
The 20+ Best Black Friday Tech Deals to Shop Right Now
  + stars: | 2022-11-23 | by ( ) www.wsj.com   time to read: +9 min
Whether you’re shopping for a smartphone, a computer, headphones or accessories, we have you covered with the best deals on tech. This deal is $20 less than the best price we’ve ever seen, and while Apple released a newer version of the streaming box this year, the benefits don’t outweigh this killer price. Apple’s MagSafe Charger is the fastest wireless charger out there. The MagSafe Duo Charger has the same benefits as the standalone MagSafe Charger, and it also includes an Apple Watch charger. Mophie’s 3-in-1 Wireless Charging Stand is marked down to $100, matching the lowest price we’ve seen.
People who got the updated booster shots after two or more shots of the original vaccine were compared to another group of people who received only two or more doses of the original vaccine. The updated booster shots performed better in preventing infections in all adult age groups, with higher vaccine efficacy seen in people who waited longer before getting the updated booster, the CDC found. He noted that studies have shown longer intervals between Covid vaccine doses can lead to higher antibody levels. Previous Covid infections may be underreported, the agency said, and low uptake of the updated boosters could have affected the results. New subvariants BQ.1.1 and BQ.1 are on the rise in the U.S., she said, and it’s unclear how the updated boosters will perform against those strains.
Pfizer-BioNTech's updated booster shot generates a stronger immune response against the omicron subvariants BA.4 and BA.5 compared with the original Covid vaccine, the companies said in a release Friday. Pfizer's original vaccine formula, which was first administered to older adults in December 2020, was designed to target the original coronavirus strain. The updated booster shot is designed to target the original virus strain, as well as BA.4 and BA.5, in a single shot. Two independent studies posted online late last month suggested that the updated shots do not offer better protection against the new omicron subvariants than the original vaccines do. The new findings may hint that the updated booster is better than the original vaccine, but not by much, said John Moore, a professor of microbiology and immunology at Weill Cornell Medical College.
An experimental RSV vaccine for pregnant women from Pfizer is effective at protecting newborns against severe illness for at least six months, the company said in a press release Tuesday. The vaccine was also about 70% effective against severe infections through the first six months of life. Pfizer said in a statement that it is currently not conducting an RSV vaccine trial in infants. Pfizer's RSV vaccine could be "a major step forward so that we can attack this last really bad communicable disease of the neonatal period," Schaffner said. Aside from pregnant women, Pfizer is testing its vaccine in older adults, who are also at risk for severe RSV infections.
Pfizer Hasn’t Moved Past the Pandemic Just Yet
  + stars: | 2022-11-01 | by ( David Wainer | ) www.wsj.com   time to read: 1 min
Pfizer ’s stock has gone from being a star in 2021 to a pharma laggard this year. Much of that has to do with the trajectory of the pandemic. Like no other large company in the U.S., Pfizer’s story has become uniquely tethered to Covid-19. Its two top products, the Covid-19 vaccine and the antiviral pill Paxlovid, are now expected to generate $56 billion in sales this year, Pfizer said Tuesday, raising the outlook for the vaccine by $2 billion. That represents around half of total sales, which the company on Tuesday predicted will come in the $99.5 billion to $102 billion range.
Pfizer’s vaccine candidate is administered to pregnant women who then make antibodies that cross the placenta and protect the baby after birth. In March, the FDA designated Pfizer’s RSV vaccine a breakthrough therapy, a status that speeds its review. Pfizer’s vaccine contains the virus’ F-protein, the site that it uses to attach to human cells. Pfizer’s RSV vaccine is bivalent, containing F-proteins from both the A and B subgroups of the RSV virus, which are the two most commonly circulating strains. “Further analysis to better understand safety data from these trials is ongoing,” spokesperson Alison Hunt said in a statement to CNN.
The number of pneumococcal vaccine doses administered in the U.S. rose 12% from a year ago. Rival drugmakers are seeking to upend Pfizer Inc.’s dominance of the $7 billion worldwide market for pneumonia vaccines, launching what is shaping up to be one of the industry’s fiercest battles. Merck & Co. has already introduced a new competitor to Pfizer’s Prevnar vaccine franchise, while GSK PLC and Vaxcyte Inc. are among companies developing shots that aim to win sales by protecting against even more strains of the pneumonia virus.
The number of pneumococcal vaccine doses administered in the U.S. rose 12% from a year ago. Rival drugmakers are seeking to upend Pfizer Inc.’s dominance of the $7 billion worldwide market for pneumonia vaccines, launching what is shaping up to be one of the industry’s fiercest battles. Merck & Co. has already introduced a new competitor to Pfizer’s Prevnar vaccine franchise, while GSK PLC and Vaxcyte Inc. are among companies developing shots that aim to win sales by protecting against even more strains of the pneumonia virus.
Drugmakers Fight Over Lucrative Pneumonia Vaccines
  + stars: | 2022-10-31 | by ( Jared S. Hopkins | ) www.wsj.com   time to read: 1 min
The number of pneumococcal vaccine doses administered in the U.S. rose 12% from a year ago. Rival drugmakers are seeking to upend Pfizer Inc.’s dominance of the $7 billion worldwide market for pneumonia vaccines, launching what is shaping up to be one of the industry’s fiercest battles. Merck & Co. has already introduced a new competitor to Pfizer’s Prevnar vaccine franchise, while GSK PLC and Vaxcyte Inc. are among companies developing shots that aim to win sales by protecting against even more strains of the pneumonia virus.
New RSV vaccines may soon put an end to rough seasons
  + stars: | 2022-10-31 | by ( Brenda Goodman | ) edition.cnn.com   time to read: +15 min
The monoclonal antibody, Synagis, is given monthly during RSV season to protect preemies and other high-risk babies. In the failed RSV vaccine trial, the chemical the researchers used to deactivate the virus denatured its proteins – essentially flattening them. Four companies have RSV vaccines for adults in the final phases of human trials: Pfizer and GSK are testing vaccines for pregnant women as well as seniors. Janssen, Pfizer and GSK each appear effective at preventing infections in adults for the first RSV season after the vaccine. The vaccines for pregnant women are meant to get newborns through their first RSV season.
Troubling recent reports reveal the emergence of new omicron subvariants that not only evade AstraZeneca’s Evusheld, the antibody drug authorized to prevent Covid infection, but also the sole antibody drug that has retained effectiveness as treatment for Covid, Eli Lilly’s bebtelovimab. Doctors have cautioned that should Laura get Covid, this could aggravate her autoimmune disease and lead to catastrophic kidney damage. Evusheld is a long-acting antibody injection given every six months that studies have suggested provides a robust buffer to the immunosuppressed. For now, immunocompromised people are anxiously watching the pandemic forecast to see if the subvariants that research indicates evade monoclonal antibodies will become predominant. “If fewer people are prescribed Evusheld,” she said, “there’s less incentive for drug companies to start developing newer therapeutics.
Pfizer plans to sell the Covid vaccine it developed with BioNTech at $110 to $130 per dose for teens and adults once the U.S. government stops paying for them, the drugmaker said Friday. Since the start of the pandemic, the government has provided Americans with free Covid tests, vaccines and treatment, through a combination of funding from Congress and other government programs. The government has already stopped providing free Covid tests. A CDC advisory committee voted Wednesday to add Covid vaccines to the Vaccines for Children program, a federal plan that provides free vaccines to children eligible for or covered by Medicaid. Pfizer said it also plans to provide free vaccines to people without insurance through its patient assistance program.
Pfizer’s Price Hike Shot in the Arm for Vaccine Makers
  + stars: | 2022-10-21 | by ( David Wainer | ) www.wsj.com   time to read: +1 min
With fewer and fewer Americans opting for Covid-19 vaccine boosters, investors had been growing increasingly skittish about vaccine-makers Pfizer and Moderna Both stocks have underperformed their peers and are among the cheapest healthcare stocks, trading well below the industry average on a price-to-earnings basis. News late Thursday that Pfizer is planning to price its shot at $110 to $130 per dose in the U.S. is giving a lift to both stocks as investors rework their models to reflect the higher revenue starting next year when Pfizer expects to transition its vaccine to the commercial market. The federal government currently covers the cost of vaccines and is paying roughly $30 per dose under the latest contract. While investors had expected a hike as that coverage lapsed, “the magnitude of the price increase was well above expectations,” wrote Chris Schott , an analyst at JP Morgan. Pfizer was up 4.5% while Moderna rose 9% in early afternoon trading.
The retooled Covid-19 booster from Pfizer Inc. and BioNTech SE generated a strong immune response against the Omicron substrains BA.4 and BA.5, the companies said. The data, which the companies reported in a news release Thursday, offer the first window into how the new shots rolling out across the U.S. perform.
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