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Guaranteed Whole Life Insurance: As you might expect, the Guaranteed Whole Life Insurance product from Mutual of Omaha comes with guaranteed coverage with no medical exams or health-related questions. Indexed universal life insurance: Another type of permanent life insurance, these flexible policies carry lifelong coverage but few guarantees. While Mutual of Omaha's term life insurance rates are average, its Guaranteed Whole Life Insurance (the company's only whole-life option) is one of the industry's cheapest insurance plans. Insider's Featured Life Insurance Companies Lemonade Life InsuranceNationwide Life InsuranceGuardian Life Insurance Chevron icon It indicates an expandable section or menu, or sometimes previous / next navigation options. Experienced life insurance agents can run quotes and advise you on premiums, life insurance loans, accelerated death benefits, and more.

☆ Health-care stocks are looking good for 2023 and not just because the sector is a 'safe haven'
▼ + stars: | 2022-12-21 | by ( Christina Cheddar Berk | ) www.cnbc.com time to read: +9 min

Investors looking for cover this year would have done well if they sought a safe haven in large-cap pharmaceutical stocks, a trend that is likely to continue into 2023. The Inflation Reduction Act provided some clarity around drug pricing that should help health-care stocks. The average price target, according to FactSet, is $62, or nearly 40% above the stock's closing price on Tuesday. Gene therapies in focus Investors will be closely watching the progress of several gene therapies, according to Phipps. "Yes, these are expensive therapies," Phipps said.

☆ How a gene-editing breakthrough from a Harvard lab saved the life of a girl with leukemia
▼ + stars: | 2022-12-19 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +6 min

A 13-year-old girl was the world's first patient to get a cell therapy called base editing in May. Base editing is a new gene-editing technology that could lead to cures for many diseases. Alyssa, 13, was the first-ever patient to receive a base-edited cell therapy after enrolling in a clinical trial in May. Base editing allows scientists to make ultraprecise changes to single letters of DNA in cells. Alyssa, a teenager in Leicester, England, received a base-edited cell therapy to treat her leukemia.

☆ Goldman Sachs upgrades Pfizer, says pharma giant can outperform even as Covid demand diminishes
▼ + stars: | 2022-12-13 | by ( Alex Harring | ) www.cnbc.com time to read: +1 min

Pfizer 's work on new products will help the company maintain its Covid momentum even as vaccine becomes a smaller business element, Goldman Sachs said Tuesday. Analyst Chris Shibutani upgraded the stock to buy from neutral with a price target of $60, which reflects a 15% upside over Monday's close. His previous price target of $47 indicated the stock would fall from Monday's close. But he said the diversity within Pfizer's pipeline bolsters optimism that the company can perform even if it has a Covid trough. Outside its the company's Covid offerings, Shibutani sees potential in its late-stage growth offerings including the RSV vaccine, Nurtec for migraines and Oxbryta within the sickle cell space.

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☆ A year after hitting a record, here are the biggest Nasdaq-100 winners and losers
▼ + stars: | 2022-11-20 | by ( Fred Imbert | ) www.cnbc.com time to read: +3 min

On Nov. 19, 2021, the Nasdaq-100 index — which is made up of the 100-largest Nasdaq Composite stocks — hit a record closing high of 16,573.34. DocuSign and Zoom Video have fallen more than 80% and 67%, respectively, since the Nasdaq-100 reached its record high. Megacap stocks such as Meta Platforms , Tesla and Amazon have also plunged over the past 12 months, in part due to their high valuations. Vertex Pharmaceuticals has rallied 69.5% since the Nasdaq-100 closed at a record. O'Reilly Automotive, T-Mobile and Gilead Sciences are also among the big Nasdaq-100 winners over the year since the Nasdaq closed at an all-time high.

☆ This little-known biotech stock can surge 60% on promising drug trials, Goldman Sachs says
▼ + stars: | 2022-11-15 | by ( Alex Harring | ) www.cnbc.com time to read: +2 min

It may be time for investors to jump into little-known biotech stock Fulcrum Therapeutics , according to Goldman Sachs. "We believe p38α/β MAPK inhibitor losmapimod has the potential to be a novel first-in-class therapy in FSHD," Kumar said in a note to clients. He has assumed a 40% probability of success and 40% peak market share for the FSHD drug. About 5% of the world's population carries the trait for hemoglobin disorders like sickle cell disease, according to the World Health Organization . Kumar said its FTX-6058 experimental drug for sickle cell disease, which is called SCD in short, has been promising in early testing.

☆ When the bakery under my apartment caught fire, my renters insurance covered everything — including a new couch I couldn't have otherwise afforded
▼ + stars: | 2022-11-11 | by ( Hannah Van Sickle | Read More | Read Less | ) www.businessinsider.com time to read: +7 min

When I was in my 20s, my boyfriend's dad all but insisted we get renters insurance. In hindsight, renters insurance turned out to be a game-changer. Here's what's covered by renters insuranceSo what's included in renters insurance rates? Insider's Featured Renters Insurance Companies Lemonade Renters InsuranceProgressive Renters InsuranceAllstate Renters Insurance Chevron icon It indicates an expandable section or menu, or sometimes previous / next navigation options. ), my experience with renters insurance lingers as a positive one.

☆ Lab-grown blood given to humans in world-first trial aimed at combatting rare disorders
▼ + stars: | 2022-11-07 | by ( Karen Gilchrist | ) www.cnbc.com time to read: +1 min

Blood grown in a laboratory has been transfused into humans for the first time in a landmark clinical trial. LONDON — Blood grown in a laboratory has been transfused into humans for the first time in a landmark clinical trial that U.K. researchers say could significantly improve treatment for people with blood disorders and rare blood types. Researchers say the aim is not to replace regular human blood donations, which will continue to make up the majority of transfusions. But the technology could allow scientists to manufacture very rare blood types which are difficult to source but which are vital for people who depend on regular blood transfusions for conditions such as sickle cell anemia. But the potential for this work to benefit hard to transfuse patients is very significant," she added.

☆ Factbox: FACTBOX How China's Communist Party Congress works
▼ + stars: | 2022-10-21 | by ( Yew Lun Tian | ) www.reuters.com time to read: +5 min

A day after the congress, the newly elected Central Committee will convene behind closed doors at its first plenum. The 200 Central Committee members with voting rights will then vote "yes" or "no" on each of the proposed candidates for the two committees. The Central Committee will then elect one person from the Politburo Standing Committee (PSC) to be the general secretary. The general secretary will then introduce his new team and speak about the work ahead. The Central Committee also approves the make-up of a new secretariat and the Central Commission for Discipline Inspection.

☆ Prime Medicine dipped 10% in its public debut. We dug through the biotech's 283-page filing to find 5 key takeaways about the company's plan to commercialize gene editing.
▼ + stars: | 2022-10-20 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +8 min

The gene-editing biotech Prime Medicine went public on Thursday. From a key patent to an uncertain timeline, here are five takeaways from Prime's filing. Its goal is to advance prime editing, a twist on CRISPR gene editing that could allow for a wider range of edits to DNA. Prime editing, another version of next-generation gene editing, works like a word processor, "searching for the correct location and replacing or repairing a wide variety of target DNA," the filing said. Jessica Rinaldi/The Boston Globe via Getty ImagesDavid Liu, a Harvard gene-editing scientist who co-invented base editing and prime editing, is Prime's largest shareholder.

☆ Factbox: How China's Communist Party Congress works
▼ + stars: | 2022-10-14 | by ( Yew Lun Tian | ) www.reuters.com time to read: +4 min

BEIJING, Oct 14 (Reuters) - Chinese President Xi Jinping is poised to win a third five-year term as General Secretary of the ruling Communist Party, the most powerful job in the country, at the 20th Party Congress that starts on Sunday. During the opening ceremony, which is broadcast with a delay, Xi will read out the 20th party congress report, reviewing the party's achievements of recent years and laying out its vision for the next five years. At the 19th party congress, the opening speech lasted 3 hours and 24 minutes. THE CLOSING CEREMONYAt the closing ceremony, typically a week after the start, delegates vote to endorse the congress report and party constitution amendment. The Standing Committee members enter in order of seniority, highest to lowest.

☆ Gene-editing companies are growing thanks to fast-paced science, even as biotech faces a downturn
▼ + stars: | 2022-10-12 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +8 min

CRISPR companies are faring better by producing faster and more dramatic clinical results. A layoff tracker from Fierce Biotech counts at least 90 drug companies that have laid off staff in 2022. Gene-editing biotechs have avoided the brunt of the downturn because of fast clinical successIntellia Therapeutics is developing CRISPR-based gene-editing medicines that could cure diseases. Just in the past month, CRISPR Therapeutics moved into a swanky new headquarters in Boston that can house up to 1,000 people. BeamTo be sure, 2022 hasn't been smooth sailing for the CRISPR companies.

☆ Prime Medicine is gearing up for a $200 million IPO. We dug through the biotech's 282-page filing to find 5 key takeaways about the company's plan to commercialize gene editing.
▼ + stars: | 2022-09-28 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +8 min

From an uncertain timeline to the clinic to a key patent, here are 5 takeaways from Prime's filing. The company's goal is to advance prime editing, a twist on CRISPR gene editing that could allow for a wider range of edits to DNA. Prime editing is another version of next-generation gene editing. Prime's filing comes in a difficult market for biotechs, but particularly for companies that have yet to start human testing. Jessica Rinaldi/The Boston Globe via Getty ImagesDavid Liu, a Harvard gene-editing scientist who co-invented base editing and prime editing, is currently Prime's largest shareholder.

☆ We went inside the lab at Vertex, a company that dodged the market downturn to become one of the best-performing biotechs of 2022
▼ + stars: | 2022-09-21 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +10 min

A mosaic of human cells inside Vertex Pharmaceuticals' cell and gene-therapy laboratory. The four-story, 267,000-square-foot space is home to Vertex's cell and gene-therapy unit, with about 375 people now residing in the modern-industrial building. That has led to going after unrelated diseases like sickle cell, diabetes, muscular dystrophy, kidney disease, and pain. For instance, Vertex's approach to sickle cell is led by its CRISPR gene-editing program. Vertex PharmaceuticalsThe next test of Vertex's strategy will be an experimental treatment called exa-cel, its CRISPR gene-editing program for sickle cell.

☆ Ancient bodies of 'vampires' were buried with rocks in their mouths to stop them returning from the dead
▼ + stars: | 2022-09-15 | by ( Marianne Guenot | ) www.businessinsider.com time to read: +6 min

Many people thought this could be stopped by putting a stone or brick in the mouths, experts said. 'Vampires' were thought to eat their way out of the grave, unless something hard stopped them. These body were not completely dead and were captured by some demonic influence," said Borrini, describing the old beliefs. This one was buried in a child cemetery on the site of the Poggio Gramignano ancient Roman villa in Teverina, Italy. Borrini defines a "vampire" as a dead person rising from the dead as a body.

☆ Archeologists discovered a 17th-century Polish 'vampire' with a sickle across its neck meant to prevent a return from the dead
▼ + stars: | 2022-09-04 | by ( Katherine Tangalakis-Lippert | Marianne Guenot | ) www.businessinsider.com time to read: +5 min

A female "vampire" skeleton was found in a 17th-century Polish graveyard. It was found restrained to prevent the dead woman from returning from the grave. The skeleton had a sickle laying across the throat and a padlock on its big toe. Professor Dariusz Poliński from Nicolaus Copernicus University headed up the archaeological dig that led to the discovery of the skeleton, the Daily Mail reported Friday. Later on, as the lore evolved, people believed that vampires were rising from the dead and strangling people the night.

☆ 10 oldest airlines in the world
▼ + stars: | 2019-03-04 | by ( Miquel Ros | ) edition.cnn.com time to read: +12 min

Here are 10 of the oldest airlines in the world still in operation. Pan American World Airways subsequently acquired a controlling stake in the company. Qantas was nationalized by the Australian government after World War II and reprivatized in the ’90s. After World War II, Aeroflot became the largest airline in the world, as air travel was often the only means of transportation available to bridge the vast expanses of the Soviet Union. Czech Airlines (CSA)Czech Airlines, the national airline of the Czech Republic.

Persons: Avianca, JUAN MABROMATA, SCADTA, Stanislav Sergeev, MICHAL CIZEK, Finnair, DANIEL SLIM, ANDREJ ISAKOVIC, Jat, Jasper Juinen, Dan Kitwood Organizations: CNN, Finnair, Czech Airlines, KLM, Passengers, Dutch, Havilland DH, Croydon Airport, Junkers F13, Pan American World Airways, SCADTA, Servicio, Qantas, Northern Territory Aerial Services, Avro, Aeroflot Aeroflot, Junkers, Aeroflot, Concorde, Communist, BOAC, CSA, Eastern Bloc, Prague City Air, DC, Delta Air Lines, AFP, Delta, Pan, Northwest Airlines, Air Serbia Air Serbia, Aeroput, Jat Airways, Etihad, Air Serbia, British Airways, Qatar Airways, International Airlines Group, British Airways British Airways, British Overseas Airways Corporation, British European Airways, Cambrian Airways, Northeast Airlines Locations: Finnish, Czech, Amsterdam, Batavia, Jakarta, New York, Colombia, AFP, Barranquilla, Germany, Colombian, SACO, Latin America, Australia, Queensland, Northern Australia, Asia, Pacific, Soviet, Moscow, Nizhny Novgorod, Russian, Soviet Union, Cuba, Murmansk, Russia, Czech Republic, Czechoslovakia, CSA, Prague, Americas, Africa, East, West Germany, Finland, Tokyo, Europe, China, East Coast, Middle, Serbia, Yugoslavia, Serbian, Air, Iberia, Madrid, Barcelona, South America, London, Paris, Devonshire

☆ North Korea needs nukes because of its religion
▼ + stars: | 2017-07-08 | by ( Paul French | Foreign Policy | ) www.businessinsider.com time to read: +9 min

But even engagement strategies can't stop the relentless move toward a deliverable North Korea nuclear arsenal. President Bill Clinton essentially attempted this in 1994 when he approved $4 billion in "energy aid" to North Korea. North Korean leader Kim Jong Un poses with participants during the 8th Congress of the Korean Children's Union (KCU) in Pyongyang, North Korea. A vendor waits for customers at the shop inside the international airport in Pyongyang, North Korea May 3, 2016. But if the world accepts a nuclear North Korea (and it accepted a nuclear Pakistan, as North Koreans have reminded me), then the second half of Kim's theory might just give the kind of pressure that can be used.

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