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The Supreme Court will soon hear a case challenging the CFPB's funding structure. Housing groups also warned of chaos in the industry if CFPB's funding is upended. But the Supreme Court threat to the CFPB's funding structure "would raise significant concerns for the stability of the housing market and the financial system more broadly," Chopra said. "Reverting to a system without these regulations would create uncertainty for the mortgage industry and the economy," Chopra said. At this point, it's unclear how broadly the Supreme Court will rule, and if it will strike down the CFPB's funding structure entirely.
Persons: Rohit Chopra, , Chopra, homebuyers Organizations: Housing, Service, Financial, Community Financial Services Association of America Ltd, Consumer Financial, Bureau, Federal Reserve, Fifth Circuit, Mortgage Collaborative National Conference, Congress, Mortgage Bankers Association, National Association of Home Builders, National Association of Realtors Locations: Wall, Silicon
Lawmakers backing the bill say a large number of companies in the state already disclose some of their own emissions. California’s climate disclosure bill would be different because of all the indirect emissions companies would have to report. But the California bill would go beyond that, by mandating that both public and private companies report their direct and indirect emissions. Companies would have to report indirect emissions including those released by transporting products and disposing waste. Companies would have to begin publicly disclosing their direct emissions annually in 2026 and start annually reporting their indirect emissions starting in 2027.
Persons: Chris Ward, Christiana Figueres, Gavin Newsom, Newsom, Sen, Scott Wiener, , , Brady Van Engelen, Danny Cullenward, Cullenward, it’s, Mary Creasman, ___ Sophie Austin, Austin @sophieadanna Organizations: , Democratic, Apple, United Nations, Democratic Gov, Lawmakers, administration’s Department of Finance, San, San Francisco Democrat, National Conference of State Legislatures, U.S . Securities, Exchange Commission, Companies, California Chamber of Commerce, Western States Petroleum Association, California Hospital Association, University of Pennsylvania’s, Center for Energy Policy, California Environmental Voters, California Air Resources Board, Wiener, Associated Press, America Statehouse News Initiative, America Locations: SACRAMENTO, Calif, California, Patagonia, Christiana, Paris, San Francisco, Ceres,
It's Harris' third trip to Southeast Asia and fourth to Asia overall, and she's touched down in more countries there than any other continent. This latest journey is another opportunity for Harris to burnish her foreign policy credentials as she prepares for a bruising campaign year. Her office has not yet detailed her schedule, but she's expected to attend summit events and hold individual talks with some foreign leaders. U.S. officials and analysts believe Beijing's aggressive approach to the region has created an opening for Washington to forge stronger partnerships. Stilwell served as the assistant secretary of state for the Bureau of East Asian and Pacific Affairs under President Donald Trump.
Persons: Kamala Harris, Loy, Kent Nishimura, she'll, Joe Biden's, It's Harris, she's, Harris, She's, Biden, John Kirby, he's, Marty Natalegawa, Natalegawa, Kirby, Phil Gordon, there's, Gordon, Ian Chong, It's, Gregory B, Poling, David Stilwell, Stilwell, Donald Trump Organizations: Cabinet, Association of Southeast Asian Nations, U.S ., ASEAN, Loy Henderson International Conference, U.S . Department of State, Los Angeles Times, Getty, Democratic, Republican, White House, of Southeast Asian Nations, Washington, National University of Singapore, Center for Strategic, International Studies, Bureau, East, Pacific Affairs Locations: U.S, Washington , DC, Southeast Asia, Jakarta, Indonesia, Asia, Washington, India, Vietnam, Myanmar, South China, United States, China, Philippines, Cambodia, South, Beijing, People's Republic of China, East Asian
Meade is executive director of the Florida Rights Restoration Coalition, which works to restore voting rights in the state to former felons. Amendment 4 automatically restored voting rights to former felons, except those convicted of murder or sexual offenses, who have completed their sentences. Initially, organizers projected that Amendment 4 would restore voting rights to about 1.4 million Floridians, but as a result of these new hurdles only a little over 600,000 have actually regained their voting rights, Meade said. Even after Amendment 4, felons are required to have completed their sentence before recovering their voting rights in Florida, as in virtually all other states. Intervening to restore those rights to Trump, if he’s convicted of a felony before the election, would represent a stark departure from the clemency board’s typical procedures.
Persons: Desmond Meade, Meade, Ron DeSantis, DeSantis, Donald Trump, he’s, ” Meade, Trump, , Insha Rahman, Neil Volz, DeSantis –, Mark Schlakman, Lawton Chiles, Republican Sen, Rick Scott, Schlakman, hasn’t, there’s, , Vera Institute’s Rahman, Ian Bassin Organizations: CNN, Restoration Coalition, Florida, Republican, GOP, Trump, Vera Institute of Justice, Florida State University, Florida Gov, District of Columbia, National Conference of State Legislatures, State, Florida State University Center, Advancement of Human, DeSantis, Republicans, Protect Democracy Locations: Florida, Maine, Vermont,
CNN —A University of South Carolina student was fatally shot early Saturday after he tried to enter the wrong home on his own street, the Columbia Police Department said – the latest case in which someone in the US was shot after apparently approaching the wrong home. “Preliminary information indicates that Donofrio who resided on South Holly Street attempted to enter the wrong home when he was fatally shot,” the release said. Police have not released any information about who shot Donofrio, adding they would consult prosecutors in the Fifth Circuit Solicitor’s Office as they investigate. The case is the latest in which the victim appears to have gone to the wrong place at the wrong time in a nation with more guns than people. South Carolina is one of at least 28 states, plus Puerto Rico, with a so-called “stand your ground” law, according to the National Conference of State Legislatures.
Persons: Nicholas Anthony Donofrio, Donofrio Organizations: CNN, University of South, Columbia Police Department, Coroner’s Office, Police, South Holly Street, South Holly, Circuit, Office, Puerto Rico, National Conference of State Legislatures Locations: University of South Carolina, Connecticut, Richland, South Holly, Columbia, South, Missouri, New York, South Carolina, Puerto
Morocco has not applied to join BRICS - state media
  + stars: | 2023-08-19 | by ( ) www.reuters.com   time to read: +1 min
REUTERS/Wu Hong/Pool/File photo Acquire Licensing RightsRABAT, Aug 19 (Reuters) - Morocco has not made a formal request to join the BRICS grouping and will not attend its summit in South Africa, state news agency MAP said on Saturday. Citing an unnamed diplomatic source, MAP denied a statement by South Africa's foreign minister Anil Sooklal who said earlier this month Morocco was among the nations seeking to join the bloc. "South Africa allowed itself to speak about Morocco's ties with the BRICS without prior consultation," it said. Morocco would not attend the BRICS meeting in South Africa, MAP said, adding: "South Africa has in fact always shown a primary hostility towards Morocco and has systematically taken negative and dogmatic positions on the Moroccan Sahara issue." Morocco is attached to a non-divisive multilateralism and has good ties with the rest of BRICS member states, it said.
Persons: Wu Hong, Anil Sooklal, Ahmed Eljechtimi, Tomasz Janowski Organizations: Xiamen International Conference and Exhibition Center, REUTERS, South, Polisario, Thomson Locations: Brazil, Russia, China, South Africa, India, Xiamen, Fujian Province, Morocco, Africa, Algeria, Western Sahara, Moroccan
For the first time, a competition saw hackers break into a US Air Force satellite in orbit. It was part of an annual event held to stress-test the satellites against real security threats. This winners, the Italian team mHACKeroni, took home $50,000. For the first time, the hackers were asked to attack a real satellite in space — the US Air Force Moonlighter, which was deployed specifically for the event. Italian team mHACKeroni won the US Air Force's fourth annual Hack-A-Sat competition by hacking into a satellite in space.
Persons: mHACKeroni, Sarah McNulty Organizations: US Air Force, Service, US Space Force, Politico, jmp, US Air, Systems Command, Viasat, Air, Financial Times Locations: Wall, Silicon, Las Vegas, Russia, China, Poland, American, Ukraine
U.S. Treasury Secretary Janet Yellen speaks during a press conference at the U.S. embassy in Beijing, China, July 9, 2023. Yellen said China's slowing growth, Russia's war in Ukraine and climate change could still pose risks to the U.S. economy and did not rule out a recession, but she felt upbeat. "I feel very good about U.S. prospects overall," Yellen told reporters, noting that inflation and the unemployment rate had both dropped below 4%, and that the U.S. economy was continuing to expand. "These are real Americans back at work – able to put food on the table, support their families, and save for retirement." Reporting by Andrea Shalal in Las Vegas; Editing by Diane Craft, Matthew Lewis and Sonali PaulOur Standards: The Thomson Reuters Trust Principles.
Persons: Janet Yellen, Thomas Peter, Joe Biden's, Yellen, Biden, Andrea Shalal, Diane Craft, Matthew Lewis, Sonali Paul Organizations: Treasury, U.S, REUTERS, Thomas, Thomas Peter Companies Ipsos, LAS, International Brotherhood of Electrical Workers, National Conference of State Legislators, Workers, International Energy Agency, Thomson Locations: Beijing, China, Nevada, Vegas, United States, Ukraine, U.S, Las Vegas
And even if Trump is not the GOP nominee in 2024, ebbing public support for the war could hurt Biden. Therefore, for political, as well as strategic reasons, there is huge pressure on Ukraine’s long-awaited counteroffensive this summer to produce significant battlefield breakthroughs. Any suggestion that Ukraine’s offensive has been bogged down will deepen that skepticism over a prolonged US commitment. Soon after the Russian invasion in February 2022, 62% said the US should do more to support Ukraine. The political dynamics in the House represent a rather precarious foundation for Ukraine’s vital US support, underscoring why a stalled offensive could represent a political disaster for Zelensky in the United States as well as a strategic loss for Ukraine at home.
Persons: Volodymyr Zelensky’s, Vladimir Putin, Joe Biden, Donald Trump, Putin, Trump, Biden, CNN’s Jim Sciutto, bleakly, Ukraine’s, Zelensky, ” Zelensky, ” It’s, Mark Hertling, ” Hertling, darkens, George H.W, George H.W . Bush, Kevin McCarthy, John Kirby, CNN’s Wolf Blitzer, He’s, Chris Christie, Nikki Haley, Mike Pence –, there’s Organizations: CNN, GOP, Senior, Ukraine, Army, Republican, Democratic, Trump Republicans, National Security, New, New Jersey Gov, South Carolina Gov Locations: US, Ukraine, Moscow, United States, NATO, Russia, Kyiv, Washington, Boston, Saudi Arabia, Crimea, George H.W ., Iowa, New Hampshire, New Jersey
Mississippi lawyers successfully argued against a lifetime voting ban for felons. These Jim Crow-era laws included a lifetime voting ban on any Mississippi resident convicted of certain felonies. Previous challenges to the law have argued it violates the Equal Protection Clause of the 14th Amendment, the Post reports. While the law is still in effect, if this latest ruling sticks, it could restore voting rights to 30,000 people in the state, according to the Post. Additional requirements in these states include indefinite bans for some crimes or additional waiting periods after someone completes their sentence.
Persons: Jim Crow, Lynn Fitch, Organizations: Service, Circuit, Washington Post, Post, National Conference of State Legislatures Locations: Mississippi, Wall, Silicon
Today, that union of minds finds refuge in Prague in a retrofitted factory building called Paralelní Polis, or "parallel world." The dark stucco of Polis' Prague headquarters is an outlier among the ornate, brightly-colored buildings that tower over it. ETHPrague 2023 was held at Paralelní Polis in the Czech Republic Pavel SinaglThe 'parallel world' concept is sticky. The Vienna branch goes so far as to self-describe as a living example of how "the Paralelní Polis cryptoliberation virus is spreading." The most popular Czech bitcoin YouTuber boasts 90k subscribers, while the annual Czech-only bitcoin conference called Chaincamp attracts around 2000 visitors, even during the bear market."
Persons: Czech Republic Pavel Sinagl, Ztohoven —, Ztohoven, provocateurs, Václav Benda, Dan Ligocký, Ligocký, William Lobkowicz, ethereum, Vitalik Buterin, Ethereum, Pavel Sinagl, Prague MacKenzie Sigalos, Holy, William, Ileana Lobkowicz, Josef Tětek, Tětek, isn't, biohacking, , Carl Menger, Friedrich Hayek, BTCPrague, Michael Saylor, Satoshi cryptographer, Adam Back, Saifedean Ammous, bitcoin, Gary Gensler, bitcoin maximalist, Vaclav, — Matěj Žák, Jan Čapek, Christoph Kassas, YouTuber Jakub Vejmola, Jameson Lopp, Stephan Livera, Robert Breedlove, Stani Kulechov, Ondrej Polak, Czech Republic Pavel Sinagl Ligocky Organizations: Paralelní, CNBC, European Union, Polis, of Cryptoanarchy, Austrian, Securities, Exchange, Czech Craft, U.S, Treasury, Casa, Ethereum Foundation, Czech Blockchain Association, optimist Locations: Paralelní Polis, Czech Republic, Czech Republic Pavel Sinagl PRAGUE, Czech, Bohemian, Prague, It's, Polis, Polis —, Lobkowicz, Nazi, Vienna, Barcelona, Bratislava, Slovakia, Košice, Austrian, ., Alza, Bohemia, Europe, Old Town, Holešovice
[1/2] A motorist rides past a hoarding decorated with flowers to welcome G20 foreign ministers in New Delhi, India, March 1, 2023. REUTERS/Amit Dave/File photoCHENNAI, India/BRUSSELS, July 28 (Reuters) - The Group of 20 (G20) major nations failed on Friday to agree on concrete targets to cut dangerous emissions, releasing only a statement that dismissed current measures to address climate change as "insufficient". Members could not agree on depleting carbon budgets, historical emissions, net-zero goals and the issue of financing to support developing countries, the document showed. China and oil-rich Saudi Arabia backed away from making commitments in the G20 talks, members of a European delegation said. The EU's Environment Commissioner said the G20 countries were "nowhere" on their commitments to address climate change.
Persons: Amit Dave, Virginijus Sinkevicius, Sarita Chaganti Singh, Aftab Ahmed, Kate Abnett, John Stonestreet, Angus MacSwan, Andrew Heavens Organizations: REUTERS, United Arab Emirates, Thomson Locations: New Delhi, India, CHENNAI, BRUSSELS, North America, Europe, China, Indian, Chennai, Saudi Arabia, Delhi, Brussels
WASHINGTON/ROME, July 27 (Reuters) - U.S. President Joe Biden hosts Italian Prime Minister Giorgia Meloni at the White House on Thursday, with the Ukraine war and Italy's relations with China expected to be among the top items on the agenda. Meloni is also expected on Thursday to meet with Republican House of Representatives Speaker Kevin McCarthy, who has said he could consider an impeachment inquiry into Biden. The G7 formally launched an alternative to Belt and Road, the Partnership for Global Infrastructure and Investment, last year. Italy is planning to discuss with the U.S. how to support the development and stability of Africa, Meloni's office said, which will also be among the main topics of Italy's G7 presidency. Reporting by Trevor Hunnicutt in Washington and Angelo Amante in Rome Editing by Don Durfee and Diane CraftOur Standards: The Thomson Reuters Trust Principles.
Persons: Joe Biden, Giorgia Meloni, Italy's, Biden, Kevin McCarthy, Meloni's, Meloni, Trevor Hunnicutt, Angelo Amante, Don Durfee, Diane Craft Organizations: Italian, White, Republican, Russia, Initiative, Partnership for Global Infrastructure, Investment, Thomson Locations: WASHINGTON, ROME, Ukraine, China, Italian, Washington, Beijing's, Italy, Beijing, Japan, Rome, North Africa, Africa
Ohio voters appear primed to pass an abortion rights constitutional amendment. According to a new poll, 58% of likely Ohio voters would vote in favor of the amendment. Ohio Secretary of State Frank LaRose must declare by tomorrow whether the abortion rights measure has enough signatures to qualify for the November ballot. As Insider previously reported, abortion rights measures could prove to deliver major political benefits to Democrats. During the 2022 midterms, abortion rights groups passed every state measure they sought and also beat back efforts to restrict abortion access.
Persons: Roe, Frank LaRose, Mike DeWine, Ohioans, Wade Organizations: Service, USA, Suffolk University, GOP, Republican Gov, Republican, National Conference of State Legislatures, The, The Mississippi Supreme, Voters Locations: Ohio, Wall, Silicon, The Mississippi
But she said more needed to be done to prevent migrants trying to make the perilous Mediterranean crossing via unauthorised means. European Commission President Ursula von der Leyen echoed Meloni's point about offering legal routes into the 27-nation European Union (EU). Europe has pledged 1 billion euros ($1.1 billion) in aid to help Tunisia with its battered economy, with 100 million euros speficially earmarked for tackling illegal migration. The EU could work with countries such as Tunisia in expanding their production of renewable energy to the benefit of all, she added. Conference host Italy is struggling to cope with the number of unauthorised migrants arriving in centres such as its far southern island of Lampedusa.
Persons: Giorgia Meloni, Meloni, Ursula von der Leyen, von der Leyen, Mohamed al, POPE, Peter's, Pope Francis, COVID, Antonio Tajani, Ahmed Elumami, Foo Yun Chee, Conor Humphries Organizations: European Union, Presidential, Conference, EU, Thomson Locations: Italian, Rome, Europe, Italy, EU, Tunisia, St, Africa, Lampedusa, Tripoli, Brussels
The hole will eventually reach 10,520 meters (34,514 feet) into the ground at the Sichuan Basin in southwest China, according to state-run news agency Xinhua. The region is a major area for gas production and engineers expected to find a natural gas reserve there, the report said. These ultradeep holes stretch greater than Mount Everest measuring from top to bottom, which is about 8,800 meters (28,871 feet) tall. Drilling deep allows scientists to learn more about how the Earth was formed with the crust acting like a geological timeline of or world’s formation. China, the world’s second largest economy and the world’s biggest carbon emitter, has huge energy needs.
Persons: Chen Lili, , Xi Jinping, John Kerry, Xi, Organizations: Hong Kong CNN, Xinhua, China National Petroleum Corporation, Sinopec Corp, Reuters, Kerry Locations: Hong Kong, Sichuan, China, Tarim, China’s, Xinjiang, Russia, Soviet, Xinhua, Beijing
New research backs her up: Volunteering has been linked with better scores on tests of cognitive function, according to research presented Thursday at the Alzheimer’s Association International Conference in Amsterdam. “We hope these new data encourage individuals of all ages and backgrounds to engage in local volunteering — not only to benefit their communities, but potentially their own cognitive and brain health.”Previous studies have found positive links between volunteering and cognitive function. These adults were around age 74 on average and had participated in the Kaiser Healthy Aging and Diverse Life Experiences Study or the Study of Healthy Aging in African Americans. Barberena thinks volunteering helps maintain her cognition by engaging her memory, verbal and reasoning skills, she said. Previous studies have found socializing and physical activity, both often involved in volunteering, to be beneficial for brain health.
Persons: Celia Barberena, Barberena, , , Donna McCullough, , it’s, Maria C, Carrillo, wasn’t, hadn’t, ” Carrillo, Yi Lor, Lor, ” Barberena, ” Lor Organizations: CNN, Alzheimer’s Association International, “ Volunteers, Alzheimer’s Association, Healthy Aging, Aging, University of California, Alliance Locations: Latina, Pacific Grove , California, Amsterdam, Davis, Monterey County, , California’s Monterey
China will cut carbon emissions at its own pace, Xi says
  + stars: | 2023-07-19 | by ( Nectar Gan | ) edition.cnn.com   time to read: +4 min
CNN —China will follow its own path to cut carbon emissions, leader Xi Jinping vowed Tuesday, as US climate envoy John Kerry called for faster action to confront the climate crisis in a high-profile visit to Beijing. Xi told a national conference on environmental protection that China’s commitment to its duel carbon goals – reaching a carbon peak by 2030 and carbon neutrality by 2060 – is “unwavering,” according to state news agency Xinhua. In the meeting with Li, Kerry stressed the “need for China to decarbonize the power sector, cut methane emissions, and reduce deforestation,” a spokesperson for the US State Department said in a statement. China and other fast developing nations have long argued that the world’s richest countries, especially those in the West, were able to become wealthy while churning out huge carbon emissions for decades. The US has said climate cooperation with China should be a standalone issue, separate from their disputes.
Persons: Xi Jinping, John Kerry, Xi, , , Kerry, Li Qiang, Wang Yi, Li, Nancy Pelosi’s, Wang, Han Zheng Organizations: CNN, Xinhua, China’s, US State Department, Taiwan –, Reuters Locations: China, Beijing, Washington, United States, Taiwan
Chronic constipation has been linked with inflammation and mental disorders such as anxiety and depression, but there have been many unanswered questions about the relationship between digestive health and long-term cognitive function, according to a news release. Cognitive function refers to a person’s mental capacity for learning, thinking, reasoning, problem-solving, decision-making, remembering and paying attention. To find clues to these queries, the authors assessed more than 112,000 adults who had participated in the Nurses’ Health Study, Nurses’ Health Study II and Health Professionals Follow-Up Study. The authors of the latest research collected data on participants’ bowel movement frequency from 2012 to 2013, participants’ self-assessments of cognitive function between 2014 and 2017, and details on some participants’ objectively measured cognitive function between 2014 and 2018. But bowel movement frequency and subjective cognitive function were also linked with the participants’ gut microbiomes, the authors found.
Persons: , Chaoran Ma, pooped, Maria C, Carrillo, wasn’t, , ” Ma, Butyrates, Ruminococcus, ” Carrillo Organizations: CNN, Alzheimer’s Association International, University of Massachusetts Amherst, Nurses, Health, Alzheimer’s Association, Cleveland Clinic, Food and Drug Administration Locations: Amsterdam, , North America
CNN —Results are in from the highly anticipated clinical trial on the Mediterranean-DASH Diet Intervention for Neurodegenerative Delay or MIND diet — a diet designed specifically to boost the brain — and they are less stellar than anticipated. Actually, the MIND diet did improve the brains of those who followed it for three years. Past studies have shown both the MIND diet and the Mediterranean diet significantly reduced the risk of cognitive decline and Alzheimer’s disease. The MIND diet also assimilates elements of the Dietary Approaches to Stop Hypertension (or DASH) diet. The DASH diet has been shown to reduce blood pressure and is the American Heart Association’s top diet.
Persons: , Lisa Barnes, Barnes, Walter Willett, Harvard T.H, Willett, “ It’s, David Katz, ” Katz, romaine, ” Willett, , Katz Organizations: CNN, Disease Research, Rush University Medical Center, Harvard, of Public Health, Harvard Medical School, True Health Initiative, Rush University, New, of Medicine, Blue Locations: Chicago, Chan, Amsterdam, American, Swiss chard
Lilly expects the U.S. Food and Drug Administration to decide by the end of this year whether to approve donanemab. The company had previously reported that 24% of the overall donanemab treatment group had brain swelling. The deaths of three trial patients were linked to the treatment, researchers reported. For high tau patients, donanemab was shown to slow disease progression by about 17%, while the benefit was 35% for those with low-to-intermediate tau levels. Both medications are also being studied in large trials to see if they have an impact on delaying onset of Alzheimer's disease symptoms.
Persons: Seth Gale, Brian Snyder, Eli Lilly, Anne White, Lilly, Susan Kohlhaas, Liana Apostolova, White, Liz Coulthard, donanemab, Deena Beasley, Ludwig Burger, Will Dunham, Bill Berkrot, Caroline Humer Organizations: Alzheimer Research, Brigham, Women’s, REUTERS, Alzheimer's Association International, U.S . Food, Drug Administration, Alzheimer’s Research, Indiana University School of Medicine, Doctors, University of Bristol, JAMA, FDA, Alzheimer's Association, Health Organization, New York Stock Exchange, Thomson Locations: Boston , Massachusetts, U.S, Amsterdam, Eisai
Treating Alzheimer’s patients as early as possible — when symptoms and brain pathology are mildest — provides a better chance of slowing cognitive decline, a large study of an experimental Alzheimer’s drug presented Monday suggests. The study of 1,736 patients reported that the drug, donanemab, made by Eli Lilly, can modestly slow the progression of memory and thinking problems in early stages of Alzheimer’s, and that the slowing was greatest for early-stage patients when they had less of a protein that creates tangles in the brain. For people at that earlier stage, donanemab appeared to slow decline in memory and thinking by about four and a half to seven and a half months over an 18-month period compared with those taking a placebo, according to the study, published in the journal JAMA. Among people with less of the protein, called tau, slowing was most pronounced in those younger than 75 and those who did not yet have Alzheimer’s but had a pre-Alzheimer’s condition called mild cognitive impairment, according to data presented Monday at the Alzheimer’s Association International Conference in Amsterdam. “The earlier you can get in there, the more you can impact it before they’ve already declined and they’re on this fast slope,” Dr. Daniel Skovronsky, Eli Lilly’s chief medical and scientific officer, said in an interview.
Persons: Eli Lilly, donanemab, , they’ve, Dr, Daniel Skovronsky, Eli Lilly’s Organizations: Alzheimer’s Association International Locations: Amsterdam
It was shown in May and in fuller Phase 3 clinical trial results released at the Alzheimer’s Association International Conference on Monday to delay the disease’s progression. More than 6 million Americans are estimated to have Alzheimer’s disease, with about 1 million estimated to be in the early symptomatic stages where these drugs have shown benefit. Both Leqembi and donanemab work by clearing buildups of a protein in the brain called amyloid, a hallmark of Alzheimer’s. It’s been a hypothesis that treating Alzheimer’s earlier with amyloid-clearing drugs would yield better results; Skovronsky said the donanemab trial bore that out. “We could look at people who had mild cognitive impairment, MCI, which is the earliest stage, versus mild Alzheimer’s versus moderate Alzheimer’s,” Skovronsky explained.
Persons: Leqembi, Eli Lilly’s donanemab, Lilly, “ Donanemab, Jennifer Manly, Kacie, , Dr, Gil Rabinovici, Renaud La Joie, Daniel Skovronsky, , Skovronsky, ” Skovronsky, It’s, Eric Widera, Sharon Brangman, University of Wisconsin’s Dr, Nathaniel Chin, Donanemab, Lilly hasn’t, Lawrence Honig, Honig, White, Sanjay Gupta, Deters, ” Lilly, it’s “, it’s, there’s, Joe Montminy Organizations: CNN, Alzheimer’s Association, Food and Drug Administration, American Medical Association, Columbia University Irving Medical Center, University of California, MCI, SUNY, University of Wisconsin’s, Leqembi, FDA, donanemab, CNN Health, ” Manly Locations: Los Angeles,
Tunisia and EU sign pact to stem migration
  + stars: | 2023-07-16 | by ( Tarek Amara | ) www.reuters.com   time to read: +2 min
The deal follow weeks of talks and Europe's pledge of major aid to Tunisia amounting to 1 billion euros ($1.12 billion) to help its battered economy, rescue state finances and deal with a migration crisis. All essential measures for bolstering efforts to stop irregular migration," Dutch Prime Minister Mark Rutte said on Twitter. The European Commission chief Ursula von der Leyens said the bloc will allocate 100 million euros to Tunisia to help it combat illegal migration. Thousands of undocumented African migrants have flocked to the city of Sfax in recent months seeking to head for Europe in traffickers' boats, amounting to an unprecedented migration crisis for Tunisia. "We are very pleased, it is a further important step towards creation of a true partnership between Tunisia and the EU, which can address in an integrated fashion the migration crisis," Italian Prime Minister Giorgia Miloni said.
Persons: Kais Saied, Giorgia Meloni, Ursula von der Leyen, Mark Rutte, Read, Europe's, Ursula von der Leyens, Giorgia Miloni, Meloni, Saied, Tarek Amara, Crispian Balmer, Anthony Deutsch, Hatem Maher, Andrew Cawthorne Organizations: Dutch, European Union, Twitter, European Commission, EU, Thomson Locations: Italian, Tunisia, EU, Tunis, TUNIS, Europe, Sfax, Rome, Italy, Libya, Amesterdam
CHICAGO, July 16 (Reuters) - An experimental Alzheimer's disease drug developed by Acumen Pharmaceuticals (ABOS.O) targeting a novel form of the toxic protein beta amyloid in the brain passed an early safety test and will advance to a larger trial, the company said on Sunday. The drug, ACI193, was well tolerated in the first trial testing it in people, the company said. Results of the randomized, placebo-controlled study of 62 patients with early Alzheimer's disease were presented at the Alzheimer's Association's International Conference in Amsterdam. In the Acumen trial, 10.4% of treated participants (5 people) developed a brain swelling condition known as ARIA-E associated with amyloid-targeting treatments. Acumen said the study suggests the drug can be given as a monthly intravenous infusion.
Persons: Eric Siemers, Leqembi, Julie Steenhuysen, Bill Berkrot Organizations: Pharmaceuticals, Thomson Locations: Amsterdam, Alzheimer's
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