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A new study suggests human ancestors nearly went extinct some 930,000 years ago. Scientists in China used modern human genomes to estimate what past populations may have looked like. It turns out our human ancestors may have faced a near miss that could have changed everything. Scientists in China last week released the results of a study that used current human genomes to make predictions about populations in the past. They found that something — perhaps an ancient climate crisis, they suggest — caused the population of human ancestors to drop drastically.
Persons: , Wangjie Hu, Nick Ashton Organizations: Service, Scientists, Icahn, of Medicine, New York Times, Africa —, Times Locations: China, Wall, Silicon, New, Mount, Africa, , Europe, Asia
'Barbie Botox' goes viral but doctors inject caution
  + stars: | 2023-09-01 | by ( Leroy Leo | ) www.reuters.com   time to read: +4 min
But since the "Barbie" movie released in July, there has been an uptick in demand for use as a cosmetic procedure. Meanwhile, Revance and Evolus Inc (EOLS.O), which make similar toxins under the brand Daxxify and Jeuveau, respectively, told Reuters that though "Barbie Botox" has picked up in recent months, they do not see the trend significantly boosting sales. However, the doctors said they were concerned about a rise in use among younger women - and six doctors warned that procedures by underqualified staff at some medispas raised the risk of complications. Doctors also stressed the risk with administration by people who may not be properly qualified, especially at medispas where there is little oversight. "The science isn't quite there yet, in order to support the clinical profile of it," said Evolus CEO David Moatazedi.
Persons: Margot Robbie, BarbieBotox, that's, Barbie, Dustin Sjuts, Scot Glasberg, Revance, Shilpi Kheterpal, Kheterpal, Doctors, Melissa Levoska, David Moatazedi, Leroy Leo, Sriraj Organizations: Therapeutics, Reuters, Plastic Surgery Foundation, U.S . Food, Drug Administration, Evolus Inc, AbbVie Inc, Cleveland Clinic, Icahn School of Medicine, Thomson Locations: New York, U.S, medispas, Mount Sinai, Bengaluru
Someone in the US has a heart attack about every 40 seconds, according to the US Centers for Disease Control and Prevention. Heart disease including heart attack is the leading cause of death in the US, but most people survive their first heart attack and go on to lead a normal life, according to the American Heart Association. Additionally, pain could be a deterrent to lifestyle changes that might lower someone’s risk of another heart attack, such as exercise. Dangas said the new study could remind doctors to pay particular attention to their heart attack patients who talk about pain. Cardiac rehabilitation cuts the risk of death in the five years after a heart attack by about 35%, according to a 2016 study.
Persons: CNN —, George Dangas, , Dangas, , Dr, Sanjay Gupta, they’ll, They’ll, Linda Vixner Organizations: CNN, US Centers for Disease Control, American Heart Association, Sinai Hospital, CNN Health, School of Health, Welfare, Dalarna University, Falun Locations: Sweden, Mount Sinai Queens, New York City, Dalarna
What’s in your tap water?” (If the drinking water is contaminated, formula mixed with it will be, too.) “But they feel heard.”Among the groups most likely to be exposed to PFAS in their drinking water are those in low-income communities or who live near military or industrial sites. determined that two kinds of PFAS — PFOS and PFOA — are “likely to be carcinogenic to humans” and proposed a goal of removing them almost entirely from public drinking water. The problem of PFAS pollution goes beyond drinking water: The Faroe Islands demonstrate as much. One afternoon this spring, Grandjean, Weihe and I sat around the kitchen table in Weihe’s clinic.
Persons: ” Elizabeth Friedman, don’t, , Friedman, he’d, Irving Selikoff, Selikoff, Grandjean, Selikoff’s, ” Grandjean, Organizations: Children’s Mercy, Children’s Mercy Kansas City, DuPont, Chermours, Toxic, European Chemicals Agency, European Union, Sinai Locations: Children’s Mercy Kansas, Missouri, U.S, United States, Paterson , N.J
The healthcare startup January uses CGMs and AI to monitor glucose levels, exercise, and sleep. I have low blood sugar, and January used machine learning to coach me to healthier habits. Low blood sugar, or hypoglycemia, is less common than high blood sugar, or hyperglycemia. Samantha Stokes/InsiderAt the end of January's AI training, I unlocked a suite of tools to track my food, exercise, blood sugar, and more. But January encouraged me to take a short walk after eating, which can help moderate glucose levels following a meal.
Persons: Marc Benioff, they're, Noosheen Hashemi, Hashemi, Marissa Mayer, Samantha Stokes, Mike Snyder, Insider's, What's, I've, CGM, didn't, Jesus Weligsander Perez Organizations: Felicis Ventures, AME Cloud Ventures, Apple Watch, Drug Administration, Stanford Medicine, Pace Locations: That's, SignalFire, Mount Sinai
CNN —Mark Margolis, a veteran actor known for his performances on “Breaking Bad” and “Better Call Saul,” has died, his son, actor and Knitting Factory Entertainment CEO Morgan Margolis, told CNN in a statement. Margolis received an Emmy nomination in 2012 for portraying Hector “Tio” Salamanca in “Breaking Bad.” Tio, a fan-favorite character, was a former cartel enforcer who communicated using a brass bell attached to his wheelchair. The fact that he didn’t have any words was not an issue for me,” Margolis told Time in 2013 of the role. Insecure is probably the word.”Margolis joked about being known for his “Breaking Bad” bell-ringing skills when he was hired to be in a commercial for an Apple watch app. Later on Friday, Cranston posted a tribute to Margolis on Instagram, writing, “Mark Margolis was a really good actor and a lovely human being.
Persons: Mark Margolis, Saul, , Morgan Margolis, Margolis, Hector “ Tio ”, ” Tio, Tio, ” Margolis, , Ventura, Oz, Darren Aronofsky, Stella Adler, , ’ ” Margolis, Vulture, Quasimodo, It’s, Saul ”, Jonathan Banks, Jacqueline, Cranston, Instagram, “ Mark Margolis, ” Cranston, ” Aronofsky Organizations: CNN, Knitting Factory Entertainment, Mount Sinai, Apple Locations: New York City, Hector “ Tio ” Salamanca, , New Mexico, New York
[1/2] A selection of injector pens for the Wegovy weight loss drug are shown in this photo illustration in Chicago, Illinois, U.S., March 31, 2023. The global market for weight-loss drugs is forecast to reach as much as $100 billion within the decade. Beyond severe mental health disorders, other patients struggling with obesity tend to suffer from mental health issues like depression and anxiety at higher levels than the general population, studies show. However, psychiatrists specializing in eating disorders are wary that drugs like Wegovy could exacerbate their patients’ focus on weight loss because they are so effective. Dr. Michael Weintraub, an endocrinologist at NYU Langone Health, said ideally psychiatrists will work with endocrinologists because weight-loss drugs require careful monitoring not related to mental health issues.
Persons: Jim Vondruska, Wegovy, Novo, It's, doggedly, Joseph Goldberg, Eli Lilly, Natalia Salomao, Dost Ongur, Brigham, Roy Chengappa, New Yorker Alexander Roger, Roger, Michael Weintraub, McLean's Ongur, Elissa Welle, Michele Gershberg, Bill Berkrot Organizations: REUTERS, Icahn School of Medicine, U.S . Food, Drug Administration, Reuters, Mass, Brigham McLean Hospital, University of Pittsburgh Medical Center, New Yorker, Fordham University, Nordisk, NYU Langone Health, Thomson Locations: Chicago , Illinois, U.S, Mount Sinai, New York, Europe, Danish, Boston
CNN —Actor Mandy Moore’s son recently woke up to a startling rash covering his body, according to her Instagram posts. Gianotti-Crosti syndrome. What is Gianotti-Crosti syndrome? Experts say they don’t know why some children get Gianotti-Crosti syndrome and others don’t, but it is thought to be a hypersensitive response to an underlying infection, according to the National Institutes of Health. Usually, the Gianotti-Crosti syndrome resolves itself over time — anywhere from a couple weeks to a couple of months, Levoska said.
Persons: Mandy Moore’s, ” Moore, Melissa Levoska, Shari Lipner, Levoska, Epstein, Barr, , ” Levoska, Lipner, Dermatologists, , it’s Organizations: CNN, Icahn School of Medicine, Weill Cornell Graduate School of Medical Sciences, National Institutes of Health, National Hospital Locations: Instagram, Mount Sinai, New York City, United States, Washington ,
Can Stress Cause Hair Loss?
  + stars: | 2023-07-11 | by ( Melinda Wenner Moyer | ) www.nytimes.com   time to read: 1 min
Q: I’ve been really stressed out at work lately and have noticed that my hair is thinning and clumping in the shower. Is it true that stress can make your hair fall out? But if you’re losing more than that, it could be a sign of a condition called telogen effluvium, or excessive hair shedding. And telogen effluvium can certainly be induced by stress, said Dr. Antonella Tosti, a dermatologist who treats hair loss at the University of Miami Miller School of Medicine. Experts don’t know exactly how common telogen effluvium is, in part because many people are not diagnosed with it.
Persons: I’ve, you’re, Antonella, Angela Lamb Organizations: American Academy of Dermatology, University of Miami Miller School of Medicine Locations: Mount Sinai, New York City
CNN —The US Food and Drug Administration is expected to decide on Thursday whether to grant traditional approval to the Alzheimer’s drug Leqembi, the first medicine proven to slow the course of the memory-robbing disease. Leqembi, from drugmakers Eisai and Biogen, received accelerated approval in January based on evidence that it clears amyloid plaque buildups in the brain that are associated with Alzheimer’s disease. But because of an earlier coverage decision by CMS, which provides insurance coverage for many elderly patients with Alzheimer’s through Medicare, the drug hasn’t been widely used. People with more advanced forms of the disease may not benefit from the drug, he said, and may face increased safety risks. Broad Medicare coverage of Leqembi and similar types of medications to slow the progression of Alzheimer’s disease would probably have a big impact on the program’s spending.
Persons: drugmakers, hasn’t, , ’ ”, Joe Montminy, Lawrence Honig, “ It’s, , Honig, it’s, Leqembi, ” Honig, Georges Naasan, Sue Rottura, ” Drugmaker Eisai, “ You’re, Ivan Cheung, Eisai, ” Montminy, Dr, Sanjay Gupta Organizations: CNN, Food and Drug Administration, Medicare, Services, CMS, Columbia University Irving Medical Center, Alzheimer’s, Behavioral, CNN Health, Kaiser Family Foundation Locations: Mount, Florida
What to Know About Eclampsia
  + stars: | 2023-06-13 | by ( Alisha Haridasani Gupta | ) www.nytimes.com   time to read: +1 min
The report identified complications of childbirth as the cause of death, listing eclampsia and respiratory distress as possible factors. “Eclampsia occurs in somewhere between one to 10 in 10,000 pregnancies,” said Dr. Joanne Stone, the head of the department of obstetrics, gynecology and reproductive science at the Icahn School of Medicine at Mount Sinai. Research has suggested that rates of hypertensive disorders of pregnancy — including pre-eclampsia, eclampsia and gestational hypertension — have been on the rise, and increased during the Covid-19 pandemic. What is eclampsia? There can be other causes of seizures during pregnancy, but it’s considered eclampsia “until proven otherwise” through lab tests, including neurological tests, Dr. Longo said.
Persons: Tori Bowie, , Joanne Stone, Monica Longo, Eunice Kennedy, Stone, it’s, Longo Organizations: The New York Times, Olympic, Icahn School of Medicine, Research, National, of Child Health, Human, National Institutes of Health Locations: Mount Sinai
Is it Bad to Wash Your Hair Every Day?
  + stars: | 2023-06-06 | by ( Jancee Dunn | ) www.nytimes.com   time to read: +1 min
Q: I’ve heard that washing your hair every day can strip it of its natural oils, making it dry and brittle and causing scalp irritation. Among them, he said, are your hair’s texture, how oily it gets, how processed it is, your lifestyle habits and your age. Shampoo cleanses your scalp and hair by removing environmental contaminants like dirt and pollen, as well as dandruff, sweat and hair-care products. It also dissolves sebum, an oily, waxy substance produced by the sebaceous glands near your hair follicles. Sebum keeps your scalp from becoming too dry, said Dr. Rosemarie Ingleton, an assistant clinical professor of dermatology at Mount Sinai Hospital in New York City, and protects the skin from infection.
Persons: I’ve, Murad Alam, Rosemarie Ingleton Organizations: Northwestern University Feinberg School of Medicine, Mount Sinai Locations: Mount, New York City
CNN —A drug used in people in the early stage of the most common kind of breast cancer – HR+/HER2- breast cancer – significantly reduced the risk of the cancer returning after treatment, according to a new study. HR+/HER2- breast cancer has tested positive for progesterone and estrogen receptors and negative for HER2. Endocrine therapy generally works well, but for patients with HR+ or HER- breast cancer, there’s still a 10% to 40% chance that the cancer will come back, some studies show. The new trial found that when Kisqali is added to endocrine therapy, it reduces the risk of recurrence by 25% across a broad population of patients with early breast cancer. About 90% of patients who have breast cancer are diagnosed in the early stages.
Persons: there’s, Kisqali, , Dennis J, Slamon, Sara Tolaney, ” Tolaney, Anupama Goel, Goel, Dr, Sanjay Gupta, Alberto Montero, ” Montero, Montero Organizations: CNN, US Food and Drug Administration, American Society of Clinical Oncology, Novartis, UCLA, Comprehensive Cancer Center, Oncology, Dana, Farber Cancer Institute, Mount Sinai Tisch Cancer Center, CNN Health, UH Seidman Cancer Center, Case Western Reserve University School of Medicine Locations: Chicago, Ohio,
Thanks to more effective screening, more women have been presenting with cervical cancer at a younger age and an earlier stage of the disease. “Simple hysterectomy can now be considered as a new standard of care for patients with low-risk early-stage cervical cancer,” Plante said. “This is a really big deal for women with cervical cancer,” said Moore, who wasn’t involved with the study. If the findings lead to a change in practice for surgeons, it could “change the trajectory of cervical cancer globally,” she said. Cervical cancer is not common in the US or Canada, Moore said, but it is endemic in low- and middle-income countries.
Persons: Dr, Marie Plante, Plante, ” Plante, , Kathleen Moore, Virginia Kerley Cade, Moore, Sanjay Gupta, ” Moore, Stephanie V, Blank, “ It’s Organizations: CNN, American Society of Clinical Oncology, National Cancer Institute, Obstetrics, Gynecology, Universite Laval, Studies, Canadian Institutes of Health Research, Canadian Cancer Society, Virginia, Developmental Therapeutics, University of Oklahoma Health Sciences Center, World Health Organization, Get CNN, CNN Health, Mount Sinai Health Locations: Chicago, Quebec, Canada
Red light therapy: How it affects sleep
  + stars: | 2023-06-01 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +7 min
CNN —Red light therapy has been found to be helpful for skin health, wound healing, hair growth among people with alopecia and pain management. “That’s why when we talk about blue light or red light, we’re not talking about a red-colored light bulb. A 2019 study led by Figueiro looked into whether delivering red light to closed eyes during sleep — using a red light mask — and to open eyes upon waking — via red light goggles — reduced sleep inertia among 30 adults. In other words, it might be that any benefits come from replacing the light you’re exposed to before sleep with red light, rather than adding the latter during sleep. The bottom line is that when it comes to sleep, “what’s better than red light is no light,” Dasgupta said.
Persons: , Raj Dasgupta, , ” Dasgupta, , Dasgupta, Joshua Tal, Mariana Figueiro, Figueiro, who’s, ” Figueiro Organizations: CNN, US Centers for Disease Control, University of Southern California’s Keck School of Medicine, Mount Sinai, Health Research Center, Icahn School of Medicine Locations: China, New York City, Mount Sinai
The strongest benefit was seen in kids who lived with dogs that were kept inside of the house, and for families who owned pets during a child's fetal development and early infancy. Owning dogs during a child's early development was associated with a lower risk of milk, egg and nut allergies, according to the new study. There wasn't a strong association found between food allergies and ownership of birds, turtles and hamsters. Research thus far has been conflicting about if having pets while a child is young is actually helpful for preventing the development of food allergies, Kwiat tells CNBC Make It. "Some studies show that early exposure to furred animal dander does protect against food allergies.
Persons: Carolyn Kwiat Organizations: CNBC Locations: Mount Sinai
CNN —The office of Sen. Dianne Feinstein, the 89-year-old California Democrat who was diagnosed with shingles in February, confirmed Thursday she “continues to have complications” from a viral infection called Ramsay Hunt syndrome. “This makes its true frequency more difficult to determine,” the Cleveland Clinic noted. Ramsay Hunt syndrome can also cause hearing loss on the side of the face affected. About 70% of people with Ramsay Hunt will regain complete or “almost complete” function of facial muscles, according to the Cleveland Clinic. Early diagnosis and prompt treatment with antiviral therapy seem to improve long-term outcomes,” the Cleveland Clinic notes on its website.
How Do I Get Rid of Skin Tags?
  + stars: | 2023-05-09 | by ( Melinda Wenner Moyer | ) www.nytimes.com   time to read: 1 min
Q: As I’ve gotten older, I’ve noticed more and more skin tags sprouting in odd places on my body. And is there anything I can (and should) do to get rid of them? They can pop up in unusual places: on your neck, under your arms, maybe even around your groin. Research suggests that more than half of adults will develop at least one skin tag during their lifetime. The good news, said Dr. Angela Lamb, a dermatologist at Mount Sinai in New York City, is that they are harmless.
U2’s Music Shaped My Life. Then It Helped Save It.
  + stars: | 2023-04-28 | by ( Theodore Kim | ) www.nytimes.com   time to read: +1 min
The Radiation Oncology department in the basement of Mount Sinai Hospital in New York does not seem like a regular home for rock ’n’ roll. But every business day for almost seven weeks this year, U2 blared over the speakers at my request. I became a fan in the late 1980s and have attended nine of the band’s concerts, though I probably fall short of superfandom. While my complication (thankfully) is on track to heal, a small bit of the tumor remains. All of my medical drama led to dozens of trips to Mount Sinai.
Healthcare startup LinusBio just raised a $16 million Series A funding round. The startup uses precision sequencing to detect autism and other complex diseases at birth. Disease detection and treatment startup LinusBio just raised a $16 million Series A funding round led by GreatPoint Ventures and Bow Capital. The startup diverges from startups like Elemy and Akili Technologies, which focus on treatment and support for people already diagnosed with autism. Check out the 16-page pitch deck LinusBio used to raise $16 million from VCs.
Dr. Gladys McGarey is the author of "The Well-Lived Life: A 102-Year-Old Doctor's Six Secrets to Health and Happiness at Every Age." It seems that almost everyone is searching for the secret to a long and happy life. In her book, "The Well-Lived Life: A 102-Year-Old Doctor's Six Secrets to Health and Happiness at Every Age," purpose is a key theme. Do some work to keep your mind engaged"I became a sacristan and didn't retire from that until I was 99," Margaret Stretton, told The Guardian. "I don't look back; I look forward."
Bill Gates' eldest daughter, Jennifer Gates, might now be calling a $51 million New York City penthouse home. 443 Greenwich Street is known for being home to other celebrities like Meg Ryan, and Blake Lively and Ryan Reynold. The penthouse apartment is 8,900 square feet and has a 3,400 square-foot outdoor space with a plunge pool. Gates' penthouse apartment is 8,900 square feet and has a 3,400 square-foot outdoor space. 443 Greenwich Street was designed with an indoor courtyard, which is rare for buildings in New York City.
Small icons of scientific papers are lined up in a grid, each representing a study of medication abortion. Studies of abortion pills Each icon represents one study that reported serious complications after medication abortion. For pregnant women considering medication abortion, the alternatives would be childbirth or procedural abortion. Almost all patients will experience bleeding and pain during a medication abortion, because the pills essentially trigger a miscarriage. But the study itself notes that bleeding is expected, serious complications are rare and medication abortion is safe.
Drivers say they're routinely getting blinded by surrounding cars' headlights. This isn't because headlight regulations have changed — regulations on brightness haven't been altered in decades. This isn't because headlight regulations have shifted — they haven't changed in decades, according to Greg Brannon, AAA's director of automotive engineering. Adaptive driving beams automatically adjust the high beams emitted from LED car headlights in real time to avoid blinding pedestrians and other drivers. So prepare for the immediate future to be even brighter, as the blinding glare problem may get worse before it gets better.
Rebellion Over College Rankings Seems Likely to Fail
  + stars: | 2023-01-27 | by ( Josh Zumbrun | ) www.wsj.com   time to read: 1 min
Harvard has is among the universities that have stopped cooperating with U.S. News & World Report on the publication’s rankings of law and medical schools. In the past two weeks, Harvard, Stanford and Columbia universities, the University of Pennsylvania and the Icahn School of Medicine at Mount Sinai said they would stop cooperating with U.S. News & World Report’s medical-school rankings. That followed the decision last year by universities including Yale, Georgetown, Harvard, Stanford, Columbia and California, Berkeley to quit cooperating on the publication’s law-school rankings.
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