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The drug, lecanemab, was associated with a type of brain swelling in 12.6% of trial patients, a side effect previously seen with similar drugs. He suggested that could be because homozygous study patients who were given a placebo fared better than expected. Overall, lecanemab patients benefited by 23% to 26% compared with a placebo on these secondary trial goals. Detailed data from the study were presented at the Clinical Trials on Alzheimer's Disease meeting in San Francisco and published in the New England Journal of Medicine. Dr. Howard Fillit, chief science officer at the Alzheimer’s Drug Discovery Foundation, said doctors always balance the benefits and risks of therapies.
There are perhaps hundreds of qualified candidates for the job of Disney's CEO. After all, returning CEOs have mixed track records. Iger was Disney's CEO for 15 years — presumably, he won't need much onboarding. In the best-case scenario, the returning CEO has learned more in the time since leaving the post. Indeed, there's always the risk that a returning CEO leans too heavily on their former experience.
Brooks was fatally shot by an officer amid national unrest over police brutality after a Minneapolis police officer murdered George Floyd. Two officers located Brooks and bodycam footage showed they had a calm conversation with him for almost 40 minutes. In the footage, Brooks could be seen holding a stun gun he had grabbed from an officer as he ran away. “While we are disappointed that prosecutors didn’t pursue a criminal case against the officers involved in Mr. Brooks’ death, we continue to hold out hope that the Dept. of Justice will intervene in this matter,” Brooks' family's attorneys said on Monday, according to WXIA.
For decades doctors have been telling their patients that high levels of HDL, otherwise known as “good cholesterol,” could protect them from heart disease. But a new study suggests that having a lot of so-called good cholesterol doesn’t mean a lower risk of heart attacks. The new findings surprised the researchers, who originally designed their study to understand how cholesterol levels in Black and white middle-aged adults without heart disease affected their future risks. Previous research on "good" cholesterol and heart disease consisted of mostly white adults. Low HDL levels were associated with an increased risk of coronary heart disease in white participants, but not Black participants.
Top 25 roundup: No. 11 Texas thrashes No. 2 Gonzaga
  + stars: | 2022-11-17 | by ( Mark Gleeson | ) www.reuters.com   time to read: +3 min
[1/5] Nov 16, 2022; Austin, Texas, USA; Texas Longhorns guard Tyrese Hunter (4) reacts after scoring a three pointer during the second half against the Gonzaga Bulldogs at Moody Center. 11 Texas connected on 13 3-pointers in a 93-74 blowout of No. Marcus Carr added 16 points and seven assists for the Longhorns (3-0), while Dylan Disu netted 12 points. Trevon Brazile registered 13 points and 10 rebounds and Davonte Davis also added 13 points for the Razorbacks (3-0). Florida Gulf Coast (2-2) was led by Zach Anderson, who had 11 points and five rebounds, while Dahmir Bishop added nine points.
Voters in states from across the political spectrum chose to enshrine abortion rights on Tuesday, a major victory for reproductive rights advocates in the first national election since the fall of Roe v. Wade in June. While the amendment’s defeat will not change whether Kentucky residents have abortion access if the state Supreme Court continues to allow a ban that is currently being challenged, abortion rights advocates were thrilled by voters’ support. Meanwhile, voters in two Democratic states, California and Vermont, chose to officially protect abortion rights in their constitutions. Democrats said they care most about abortion rights, while Republicans said their biggest concern was inflation, according to the poll. “Until there’s a new federal right, state constitutions are really the best avenue to ensure reproductive rights and abortion rights in any given state,” she said.
On October 31, 1981, 11-year-old Karl Heikell told his parents he was going out for a walk in his town of Calumet, Michigan. “And sure enough, I found newspaper clippings about Karl Heikell going missing.”The young librarian was eager to learn more about this local mystery. Cleary told Dateline. “It's a shame that so many people have Billy in their heads as this” kind of person, he told Dateline. Detective Cleary told Dateline that after Billy’s suicide, police looked into his possible involvement in the case.
CNN —Some throwbacks to notable ’90s-era celebrities were standouts as the stars stepped out this weekend in costume for their Halloween festivities. One couple acknowledged a pair that came before them, when Megan Fox and Machine Gun Kelly channeled Pamela Anderson and Tommy Lee, respectively, at the Casamigos Halloween Party Returns in Beverly Hills, California on Friday night. Josh Duhamel and Audra Mari at the Casamigos Halloween Party Returns in Beverly Hills on Friday in Beverly Hills, California. at the Casamigos Halloween Party Returns in Beverly Hills, California on Friday. Vanessa Hudgens as Black Swan at the Thriller Night Halloween Party, hosted by Prince Michael Jackson, at the Jackson Family Home in Encino, California on Friday.
But inside the walls at Ware, one of the state’s largest juvenile detention facilities, children have been trying to kill themselves with stunning regularity. In Louisiana, where brutal conditions prompted juvenile justice reform two decades ago, the system is again in crisis. Most Ware guards are Black, as well, though nearly all of its leaders are white, as are the local judge, sheriff and district attorney. “Of course, they still do.” In reports to the state, Ware’s nurses described carpet burns on children’s faces and head-to-toe bruises from restraints. In fact, of the four guards convicted of sexually assaulting children at Ware, Mr. Peace would be the only one imprisoned.
A town employee who quietly lowered the fluoride in a Vermont community’s drinking water for years has resigned — and is asserting that the levels had actually been low for much longer than believed. While fluoridating municipal water is voluntary, Vermont towns that do “shall control the level of fluoride” within the state’s specified ranges, according to the state’s water supply rule. The Vermont Health Department said it does not regulate municipal water systems. Town Manager Josh Arneson said Thursday that he will review fluoride levels monthly and that the town’s Water and Sewer Commission will also look at the report. The addition of fluoride to public drinking water systems has been routine in communities across the United States since the 1940s and 1950s.
The country's largest online source of JFK assassination records is suing President Joe Biden and the National Archives to force the federal government to release all remaining documents related to the most mysterious murder of a U.S. president nearly 60 years ago. “This is about our history and our right to know it,” said Morley, the author of the JFK Facts blog. The National Archives and Records Administration, the agency in charge of the JFK documents, also said it’s complying with the law and the procedures Biden outlined. JFK assassination historian David Talbot, a Trump critic, said he sees an irony in the two cases. Uscinski said he’s hesitant to draw a direct line between lack of trust in the government and the refusal to release the JFK records, but he argued the feds essentially have themselves to blame.
And the intent of this comedy-thriller is showing how wrong he can be. For such a committed Halloween skeptic, Howard clearly hasn’t scoped out Bridge Hollow very well. It’s a place that loses its otherwise decorous mind as it approaches Oct. 31. She’s tired of Howard, the intellectual dictator, pushing her toward science all the time. She prefers to dabble in the supernatural, which means she’s delighted to meet up with members of the Bridge Hollow Paranormal Society—all three of them—who in turn are delighted to meet the new resident of the old Hawthorne House.
When Casey Howard and her client saw the Studio Bel Vetro Light Drop chandelier in a showroom, they had an “aha” moment. “We both agreed it was perfect; it’s sculptural in the day and twinkles above the lights at night,” says Ms. Howard, principal designer and owner of Danville, Calif.-based Casey Howard Interior Design. The house has large windows along a curved exposure that maximize views of the San Francisco Bay, Oakland and San Francisco. In the dining room, those windows—plus stairs that curve into the space—create a room with few right angles. “Because it’s a semicircle, the space presented some design challenges,” Ms. Howard says, noting that the unusual shape led to some innovative solutions.
Robbie Parker was later falsely called a crisis actor, and the Parkers are among those who sued Alex Jones for defamation. Longtime informal adviser to Donald Trump, Roger Stone (right), and and Alex Jones (left) speak to reporters in December 2018. Picture showing a computer screen displaying the Twitter account of Far-right conspiracy theorist Alex Jones taken on August 15, 2018 in Washington DC. "Alex Jones is likely to continue being Alex Jones, which means he's likely to try all kinds of shenanigans to avoid accountability," said Holt. "The money awarded in damages does not repair what Alex Jones has done to those parents' lives, but it could be a step towards dismantling the toxic empire that Alex Jones has built around his brand."
Canadienii care au fost imunizați cu prima doză a vaccinului AstraZeneca pot primi a doua doză fie din acelaşi vaccin, fie o doză de vaccin cu ARN mesager (Pfizer-BioNTech sau Moderna), conform unui anunţ făcut marți de către Comitetul consultativ naţional pentru imunizare (CCNI), informează AFP, citată de Agerpres. În formularea acestei recomandări, CCNI precizează că a luat în considerare în special riscul formării de cheaguri de sânge grave în cazul vaccinului AstraZeneca, scrie libertatea.ro. „Caracterul interschimbabil al vaccinurilor înseamnă că puteţi primi o primă doză de vaccin şi puteţi primi în siguranţă un vaccin diferit pentru a doua doză pentru a completa seria de vaccinuri necesare pentru a asigura o protecţie optimă împotriva COVID-19”, a dat asigurări dr. Howard Njoo, adjunct al administratorului şef al sănătăţii publice federale. Vaccinul AstraZeneca continuă însă să fie utilizat pentru persoanele care au primit o primă doză şi doresc să fie imunizate cu a doua doză a aceluiaşi vaccin. Decizia de a aplica sau nu această recomandare revine provinciilor canadiene.
Persons: Howard Njoo Organizations: Agerpres Locations: canadiene
Sursa foto: mediafax.roCanada a autorizat utilizarea unui vaccin anti-COVID-19 diferit pentru a doua dozăCanadienii care au fost imunizați cu prima doză a vaccinului AstraZeneca pot primi a doua doză fie din acelaşi vaccin, fie o doză de vaccin cu ARN mesager (Pfizer-BioNTech sau Moderna), conform unui anunţ făcut marți de către Comitetul consultativ naţional pentru imunizare (CCNI), informează AFP, citată de Agerpres. În formularea acestei recomandări, CCNI precizează că a luat în considerare în special riscul formării de cheaguri de sânge grave în cazul vaccinului AstraZeneca. „Caracterul interschimbabil al vaccinurilor înseamnă că puteţi primi o primă doză de vaccin şi puteţi primi în siguranţă un vaccin diferit pentru a doua doză pentru a completa seria de vaccinuri necesare pentru a asigura o protecţie optimă împotriva COVID-19”, a dat asigurări dr. Howard Njoo, adjunct al administratorului şef al sănătăţii publice federale. Vaccinul AstraZeneca continuă însă să fie utilizat pentru persoanele care au primit o primă doză şi doresc să fie imunizate cu a doua doză a aceluiaşi vaccin. Decizia de a aplica sau nu această recomandare revine provinciilor canadiene.
Persons: Howard Njoo Organizations: Agerpres Locations: Canada, canadiene
Howard a fost asociat cu crima de un medic care a comparat semnele mușcăturilor de pe corpul victimei cu dinții lui Howard. Dar, în luna august, Curtea Supremă din Mississippi a admis că această comparație nu era suficientă pentru a-l lega de crimă pe Howard și a afirmat că „un autor nu poate fi identificat în mod corect prin comparație cu urma mușcăturii”. Ca urmare, sentința de condamnare la moarte a fost anulată. Howard a fost mutat din secția destinată condamnaților la moarte în decembrie, iar la finele săptămânii trecute a fost exonerat. „Vreau să mulțumesc oamenilor care m-au ajutat să-mi îndeplinesc visul de a deveni un om liber”, a spus Howard într-o declarație.
Persons: Howard, Kemp, CNN . Howard, Howard . Organizations: Justiției Locations: Columbus, Mississippi, Statele Unite, SUA
The Tucker Carlson origin story
  + stars: | 1998-01-28 | by ( Aaron Short | ) www.businessinsider.com   time to read: +57 min
Tucker Carlson is remembered as a provocateur and gleeful contrarian by those who knew him in his early days. It was Tucker Carlson. (Note on style: Tucker Carlson and the members of his family are referred to here by their first names to avoid confusion.) In 1979, Richard Carlson married Patricia Swanson, heiress to the Swanson frozen foods empire that perfected the frozen Salisbury steak for hassle-free dinners. Tucker Carlson attended St. George’s School, a boarding school starting at age 14.
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