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But by this point she had a half-dozen blood cultures, plus the ones that were done when she arrived at Penn Presbyterian, and none of them showed the presence of bacteria. Ammazzalorso knew that some of the bugs that cause endocarditis don’t show up in blood cultures. When Ammazzalorso finally left the patient’s room, she sat at the computer and considered what tests should be ordered. Certainly, more blood cultures. Blood cultures look for organisms in the circulation.
Persons: Alyssa Ammazzalorso, Ammazzalorso, Bartonella, Judith O’Donnell, Organizations: University of Pennsylvania, Penn Presbyterian
CNN —A novel trial that has been described as “the last roll of the dice” for a generation of HIV vaccines has entered its latter stages. Nearly 40 years since HIV was identified as the cause of AIDS, and 36 years since the first HIV vaccine trial, the medical community still does not have a working vaccine. But that is not necessarily why they were chosen to participate, said Eugene Ruzagira, PrEPVacc trial director. Evaluating the combination of a trial HIV vaccine and PrEP is a first, say organizers. “I did my very first HIV vaccine trial in 1991,” recalled Weber.
Persons: PrEPVacc, , Jonathan Weber, Frank, Helena Herholdt, Eugene Ruzagira, Ruzagira, , Weber, ” Ruzagira, “ We’ve, Mark Runnacles, Edward Jenner, Louis Pasteur, Galileo, Win McNamee, Humphry Davy, JEAN, SEBASTIEN EVRARD, Haydn West, Joe Raedle, ANNE, CHRISTINE POUJOULAT, Alexander Fleming, Fleming, wasn't, Louise Joy Brown, Sandy Huffaker, Daniel Acker, James Watson, Francis Crick, Rosalind Franklin, Watson, Crick, Raphael GAILLARDE, Sean Gallup, Wilhelm Conrad Röntgen, Thomas Edison's, INDRANIL MUKHERJEE, Descovy, Luwano Geofrey, Dr, Luke Dray, Geofrey, Nishanta Singh, Sharon Lewin, Lewin, “ it’s, it’s, ” Lewin, ” Geofrey Organizations: CNN, Imperial College Academic Health Science Centre, PrEPVacc, Medical Research, Uganda Virus Research Institute, European Union, Smithsonian National Museum of, Cleveland Clinic, Volvo, Bayer, U.S . Food, Drug Administration, Getty, Keystone, — Farmers, Food and Drug Administration, FDA, Bloomberg, PANTHAKY, PrEP, US Centers for Disease Control, Independent, The University of Melbourne, International AIDS Society, Muhimbili University of Health, Allied Sciences, Dar Locations: Entebbe, Uganda, Thailand, London, Mbeya, Tanzania, South Africa, Ugandan, Durban, Masaka, Salam, African, Africa, China, FPG, AFP, United States, America, U.S, Peoria , Illinois, Europe, , Dar es Salaam, Rwanda
It’s Toxic Slime Time on Florida’s Lake Okeechobee
  + stars: | 2023-07-09 | by ( ) www.nytimes.com   time to read: +14 min
For thousands of years, Lake Okeechobee pumped life into Florida’s swampy interior. Lake Okeechobee 10 miles Lake Okeechobee 5 miles Lake Okeechobee 5 miles Algal bloom extent on June 12 Source: Satellite image by Landsat By Leanne AbrahamRainy season is just starting, but by late June the lake’s level was roughly two feet higher than the United States Army Corps of Engineers would like. Sunrise over Pahokee and Lake Okeechobee. “Like clockwork.”Similar outbreaks have struck lakes elsewhere, including Lake Champlain, Lake Erie and Lake Tahoe. Equally challenging to grasp is the idea that the whole new lake, as big as it sounds, will fill to capacity if only six inches of Lake Okeechobee is sent its way.
Persons: Ian, Fort Myers, Stuart —, Leanne Abraham Rainy, , Star Robinson, it’s, Herbert Hoover, Palm Beach Herbert Hoover, Leanne Abraham, Gil Smart, Robinson, It’s, Herbert Hoover Dike, Roy Senff, Okeechobee’s outflows, Sherwin, Williams, Hoover, Stuart, Nature, Col, James Booth of, Tim Harper, , Biden, Ron DeSantis, Eric Eikenberg, Bill Mitsch, Mother Nature, Floridians, Stefani Hughes, Smart, VoteWater aren’t, They’re Organizations: United States Army Corps, Engineers, Army Corps of Engineers, Orlando Area, Air, Palm Beach Herbert, Everglades, States Geological Survey, Everett, Inc, Fort, Florida Water Management District, Florida Legislature, Gov, Everglades Foundation, Research, Florida Gulf Coast University Locations: Okeechobee, Fort, Pahokee, Lake Okeechobee, Ala, Orlando, Fla, Kissimmee, Florida, Myers, Gulf, Mexico, Miami, Ga, Palm, Everglades Miami, Lake Champlain, Lake Erie, Tahoe, Stuart, U.S.D.A, Manhattan, South Florida
New York CNN —Soon, Americans are going to able to try chicken that comes directly from chicken cells rather than, well, a chicken. On Wednesday, the USDA gave Upside Foods and Good Meat the green light to start producing and selling their lab-grown, or cultivated, chicken products in the United States. In a nutshell, lab-grown meat — or cultivated or cell-based meat — is meat that is developed from animal cells and grown, with the help of nutrients like amino acids, in massive bioreactors. Meat eaters who are concerned about those types of risks might prefer cultivated meat. Eat Just Inc's Good Meat cultivated chicken.
Persons: New York CNN —, It’s, don’t, Andrew Noyes, Noyes, , Bruce Friedrich, Friedrich, Julia Horowitz, ” Noyes, José Andrés, Ivy Farm, That’s, Noyes didn’t, Matthew Walker, Walker, won’t, , — CNN’s Kristen Rogers Organizations: New, New York CNN, USDA, Inc, Good Food Institute, Impossible Foods, CNN, Ivy Farm Technologies, Service, FDA, British, Ivy, Companies, Foods Locations: New York, United States, Agriculture, British, Italian, Singapore, Washington, San Francisco
More than 13% of passengers on board the Viking Neptune this month fell ill with norovirus, the CDC said. The health agency has already logged 13 outbreaks of the contagious virus on cruise ships this year. The Viking Neptune transformed into a cross-continental petri dish as more than 100 passengers onboard the cruise ship fell ill with the highly contagious norovirus this month. Gastrointestinal illnesses have long been frequent guests aboard cruise ships, where cramped quarters allow germs to spread easily, and the highly contagious norovirus is the most notorious cruise ship culprit. In March, more than 300 people on board a Princess Cruise ship fell ill with the virus, and another outbreak hit 177 people traveling on a Celebrity Cruise ship earlier this month.
Persons: Viking Organizations: CDC, Morning, Centers for Disease Control, Viking Cruises, Sanitation Locations: Iceland, New York, Greenland, Canada
The startup Loam Bio wants to use fungi to boost soil health and help keep carbon in the ground. But soil carbon is in a sorry state, in part due to current agricultural practices. There are different types of soil carbon; some decompose easily while others can take thousands of years to break down. The soil microbiome could also change to start breaking down the carbon that gets fixed in soil, Bailey added. "The most important thing is that we're really accurately measuring the carbon that we store in the soil," Hudson said.
Persons: Guy Hudson, Chris Sacca's, Hacking, It's, Hudson, Monique, Britt Koskella, Koskella, Andy Bailey, Bailey, we're, Chris Shafto, Dr Brooke Bruning, you've Organizations: Green Tech, Service, Australian, Lowercarbon Capital, Lowercarbon, UC Berkeley, University of Bristol Locations: Australia, Brazil
Recently, Yunnan province was gripped with temperatures of more than 40 Celsius, which is especially burdensome for power grids as millions of homes begin to switch on air conditioners. read moreOver the past couple days, Shandong province and Beijing issued heat warnings. Populous cities such as Jinan, Tianjin and Zhengzhou are expected to see temperatures soar to as high as 37 degrees Celsius. The China Meteorological Administration has warned regions to prepare for more extreme heat this year. The World Meteorological Organization's (WMO) latest assessment also predicts the strong likelihood of the El Niño weather phenomenon returning later this year.
J. Alexander, who used to work for cruise ships, took more than 20 cruises last year. He said his favorite cruise was to Antarctica and that Royal Caribbean is his favorite cruise line. Every cruise line does something better than another cruise line. Treat the cruise crew members with respectOne six-month contract aboard a cruise ship, you will see it all. One time I was working on board a cruise ship and me and the rest of the entertainment went out.
Sen. Sherrod Brown, D-Ohio, for years claimed an owner-occupancy tax credit at two properties, public records show — a potential violation of the state's rules governing such incentives. Responding to questions from NBC News, Brown and Schultz this week paid a $390 penalty stemming from their most recent late payment. Brown will no longer accept the owner-occupancy credit on the Columbus property, according to his campaign. Franklin County tax records available online show no late payments or penalties for Brown's Columbus condo — purchased in 2014 — over the last four years. Ohio schools are heavily reliant on property tax revenue, and late payments affect their accounting.
Altman told Insider, "We debate our approach frequently and carefully." "I don't think anyone can lose your dad young and wish he didn't have more time with him," Altman told Insider. Altman told Insider that his thinking had evolved since those posts. (When asked about guns, Altman told Insider he'd been "happy to have one both times my home was broken into while I was there.") When asked about this, Altman told Insider in an email: "i can guess what that's about; these stories grow crazily inflated over the years of getting re-told!
But, "you do at some point need to start having contact with reality," he told Insider. The plan was still only a rough sketch, Blania told Insider, but that didn't seem to matter to his host. "He always wanted to understand everything at a very deep level," Thrun told Insider in an email. (When asked about guns, Altman told Insider he'd been "happy to have one both times my home was broken into while I was there.") When asked about this, Altman told Insider in an email: "i can guess what that's about; these stories grow crazily inflated over the years of getting re-told!
A Litany of Clichés - The New York Times
  + stars: | 2023-04-27 | by ( Michael Massing | ) www.nytimes.com   time to read: +4 min
Ramped up, amped up, ratchet up, gin up, up the ante, double down, jump-start, be behind the curve, swim against the tide, go south, go belly up, level the playing field, open the floodgates, think outside the box, push the edge of the envelope, pull out all the stops, take the foot off the pedal, pump the brakes, grease the wheel, circle the wagons, charge full steam ahead, pass with flying colors, move the goal posts, pour gasoline on, add fuel to the fire, fly under the radar, add insult to injury, grow by leaps and bounds, only time will tell, go to hell in a handbasket, put the genie back in the bottle, throw the baby out with the bathwater, rearrange the deck chairs on the Titanic, have your cake and eat it too, a taste of one’s own medicine, stick to one’s guns, above one’s pay grade, punch above one’s weight, lick one’s wounds, pack a punch, roll with the punches, come apart at the seams, throw a wrench into, caught in the cross hairs, cross the Rubicon, tempt fate, go ballistic, on tenterhooks, hit the nail on the head, a nail in the coffin, joined at the hip, welcome with open arms, rub shoulders with, shoot oneself in the foot, dip one’s toes into, have a leg up, dance to the tune of, the next shoe to drop, in the DNA of, the gold standard, a gold mine, land mines, a run for the money, money to burn, penny-wise and pound-foolish, lap of luxury, off the charts, over a barrel, late to the party, it takes two to tango, behind the eight ball, pride of place, final straw, full throttle, no holds barred, red flag, silver lining, on a silver platter, in the rearview mirror, bargain basement, silos, morph, meme, trope, mind meld, warp speed, inner demons, have skin in the game, game changer, change agent, strong suit, ground game, ground zero, inflection point, tipping point, playbook, page turner, singing from the same hymnal, singing a new tune, straight out of central casting, the devil’s in the details, take the bull by the horns, the canary in the coal mine, chickens coming home to roost, beat a dead horse, pony up, the straw that broke the camel’s back, open a can of worms, buy a pig in a poke, cash cow, rabbit hole, dog days, dog whistle, bells and whistles, tool kit, third rail, the tip of the iceberg, the light at the end of the tunnel, the arc of history, speak truth to power, break the glass ceiling, the writing’s on the wall, between a rock and a hard place, beyond the pale, take the wind out of the sails of, that ship has sailed, sinking ship, tidal wave, roller-coaster ride, gravy train, tanked, cratered, Rubik’s Cube, Rosetta Stone, Rolodex, poster child, problem child, rock star, pundit, national treasure, charter member, heavy hitter, heavy lifting, political football, throw a Hail Mary, full-court press, hit a home run, play with house money, laser-focused, secret sauce, red meat, piece of cake, bread and butter, cherry-pick, low-hanging fruit, sticker shock, kick-start, kick into overdrive, kick the tires, kick the can down the road, where the rubber meets the road, an albatross around the neck, a feather in the cap, long in the tooth, armed to the teeth, cut one’s teeth, rib tickler, spine tingling, pull the wool over the eyes of, pull the plug on, pull the trigger, loosen the reins, sweep under the carpet, throw under the bus, throw for a loop, read the riot act, lead the pack, the short end of the stick, at the drop of a hat, the jury is still out, hung out to dry, as if that weren’t enough, it would be an understatement to say, it would be no exaggeration to say, despite or perhaps because of, what goes around comes around, for all intents and purposes, make a long story short, the fact of the matter, to be sure, truth be told, a who’s who, famously, arguably, literally, zeitgeist, mantra, optics, granular, narrative, interrogate, paradigm, venue, robust, compelling, fever pitch, pitch perfect, picture perfect, perfect storm, take by storm, eye of the storm, back burner, petri dish, echo chamber, hot button, hard wire, go viral, bingeable, blockbuster, on steroids, testosterone-laced, metastasize, contextualize, preternaturally, outsize, gobsmacked, turbocharged, weaponized, apocalyptic, existential …
Identity and email management company Lockr raised $2.5 million in pre-seed funding this week. Check out the pitch deck that convinced investors like Mozilla Ventures to join the funding round. Lockr, a digital identity management startup, said this week it had raised $2.5 million in pre-seed funding, investment it plans to use to grow its team, scale its userbase, and add more features to its consumer product. For publishers and marketers, the company provides Lockr Identity. Investors in Lockr's pre-seed funding round included Mozilla Ventures, Junction Venture Partners, and Grit Capital Partners, as well as individual investors.
Climate change may be driving the rapid spread of Candida auris, a deadly fungus, across the US. Three charts show how extreme weather and environmental changes help spread disease. Nicolas Armer/picture alliance via Getty ImagesA leading theory on this fungus's sudden emergence and wide spread is that it's fueled by climate change. Whatever survives, however, is adapted to extreme heat — including the fever our bodies produce to kill off pathogens. David Ryder/Getty ImagesHumans and their infrastructure are more vulnerable to the devastating impacts of disease when they're compromised by extreme weather.
"The Last of Us" on HBO Max depicts a zombie apocalypse caused by a fungus pandemic. Here's the science fact and fiction behind the show, and the possibility of a fungal pandemic. The new scenario, first realized in the video game that the show is based on, is making viewers wonder whether a fungus pandemic can happen in real life. "A fungal pandemic is definitely possible," Norman Van Rhijn, a mycologist researching fungal infections at the University of Manchester, told Insider in an email. Still, fungal infections are on the rise worldwide, and researchers are concerned that more and more people are at risk.
Feb 14 (Reuters) - A divided U.S. appeals court on Tuesday said federal workers are generally not entitled to extra pay for being exposed to COVID-19 through their jobs. In a 10-2 decision with potentially "far-reaching" ramifications, the U.S. Federal Circuit Court of Appeals ruled against 188 current and former correctional employees at a federal prison in Danbury, Connecticut. But the appeals court said the government's Office of Personnel Management, the human resources agency for more than 2.1 million federal workers, had no regulations affording extra pay for exposure in most settings to contagious diseases. Circuit Judge Jimmie Reyna dissented, saying the prison employees plausibly alleged they deserved extra pay for exposure to "unusually" hazardous conditions. The decision is Adams et al v U.S., U.S. Federal Circuit Court of Appeals, No.
When a middle-aged man who had suffered a seizure was admitted to the University of California San Francisco Medical Center in 2021, doctors seeking the cause for his condition quickly became stumped. After pathologists spent two weeks peering through microscopes and monitoring petri dishes, doctors knew something serious was harming the patient’s brain; they had no idea what it was or how to treat it.
When a middle-aged man who had suffered a seizure was admitted to the University of California San Francisco Medical Center in 2021, doctors seeking the cause for his condition quickly became stumped. After pathologists spent two weeks peering through microscopes and monitoring petri dishes, doctors knew something serious was harming the patient’s brain; they had no idea what it was or how to treat it.
When a middle-aged man who had suffered a seizure was admitted to the University of California San Francisco Medical Center in 2021, doctors seeking the cause for his condition quickly became stumped. After pathologists spent two weeks peering through microscopes and monitoring petri dishes, doctors knew something serious was harming the patient’s brain; they had no idea what it was or how to treat it.
The new HBO Max series "The Last of Us" depicts a zombie apocalypse caused by a fungus pandemic. Here's the science fact and fiction behind the show, and the possibility of a fungal pandemic. The new scenario, first realized in the video game that the show is based on, is making viewers wonder whether a fungus pandemic can happen in real life. "A fungal pandemic is definitely possible," Norman Van Rhijn, a mycologist researching fungal infections at the University of Manchester, told Insider in an email. Still, fungal infections are on the rise worldwide, and researchers are concerned that more and more people are at risk.
In fact, the results reaffirm the reason why some dermatologists have changed the way they get their gel manicures or have stopped getting them altogether. “Tanning beds are listed as carcinogenic and UV nail lamps are mini tanning beds for your nails in order to cure the gel nail,” Curtis said. “I would recommend alternatives to gel nails, such as the new wraps that are available online.” (Gel nail wraps or strips are stick-on gel nail products that don’t always require being set by UV nail dryers.) Some salons use LED lights, which “are thought to emit either no UV light or much, much lower amounts,” Lipner said. Russak doesn’t get gel manicures very often but uses sunscreen and gloves when she does, she said.
Persons: , Julia Curtis, wasn’t, ” Curtis, Ludmil Alexandrov, ” Alexandrov, Julie Russak, Russak wasn’t, there’s, ” Russak, Shari Lipner, Lipner wasn’t, Curtis, , ” Lipner, Lipner, , Russak, Joshua Zeichner Organizations: CNN, Nature Communications, University of Utah, UCAR Center for Science Education, University of California, Dermatology, Presbyterian Hospital, Weill Cornell Medical Center, Mount Sinai Locations: San Diego, New York City, corneocytes, Mount
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailChina's population is a 'petri dish' for Covid, says Dr. Kavita PatelDr. Kavita Patel, NBC News and MSNBC medical contributor, joins CNBC's 'Squawk Box' to weigh in on China's response to Covid-19 and what's next for the virus' spread.
China’s Let-It-Rip Covid Reopening
  + stars: | 2022-12-23 | by ( Ezekiel J. Emanuel | ) www.wsj.com   time to read: 1 min
China put the world in peril with its coverup and slow response to the emergence of SARS-CoV-2 three years ago. The country’s current approach to Covid-19 is creating new risks—in China and beyond. Xi Jinping has made an abrupt about-face—swinging from total Covid suppression to population-wide immunity through viral spread. Chinese experts predict a Covid explosion, with hundreds of millions of cases. China will also become a petri dish for new variants, which will inevitably spread globally.
You might want to think twice before reaching your hands under a hot-air dryer after using a public restroom. Because you could be covering your freshly cleaned hands — with more bacteria. A 2018 study conducted a test to determine if hand dryers in public bathrooms could be dispensing bacteria onto people's hands. To investigate this, researchers exposed petri dishes to the air in bathrooms in various conditions, and brought the dishes back to their lab to see if bacteria was growing on them. But, "petri dishes exposed to hot air from a bathroom hand dryer for 30 seconds grew up to 254 colonies of bacteria (though most had from 18 to 60 colonies of bacteria)."
Democracy remains vulnerable despite a good year
  + stars: | 2022-12-12 | by ( Hugo Dixon | ) www.reuters.com   time to read: +7 min
PARIS, Dec 12 (Reuters Breakingviews) - Aristotle said there are three good forms of government – monarchy, aristocracy and constitutional democracy – in which the rulers act for the common benefit. Rich democracies face two main threats: an external one from autocracies, such as China; and an internal one from demagogues. Both autocrats such as Chinese President Xi Jinping and demagogues such as former U.S. President Donald Trump have had a bad year. The world economy faces a tough decade. Until democrats provide some answer to this, they will be vulnerable to new waves of autocracy and demagogy.
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