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About 1 in 8 adults over 50 showed signs of food addiction, according to the survey. “We think this is also true in younger populations.”Gearhardt and her team used questions from the Yale Food Addiction Scale to measure whether older adults were experiencing core indicators of addiction. If I had emotional problems because I hadn’t eaten certain foods, I would eat them (17%, once a week). Gearhardt was a member of the group that devised the Yale Food Addiction Scale. The difference is you can’t stop eating food.”Gearhardt said that the survey results should encourage health providers to ask patients about dietary habits.
Do Overweight Kids Need Pills?
  + stars: | 2023-01-16 | by ( Allysia Finley | ) www.wsj.com   time to read: 1 min
Childhood obesity rates have been climbing since the 1970s, but kids have never packed on as many pounds as quickly as they did during Covid shutdowns. According to one study, the share of 5- to 11-year-olds classified as obese ballooned by nearly 40% between March 2020 and January 2021. About 1 in every 4 kids by the end of the study was considered obese. The AAP last week recommended weight-loss drugs and bariatric surgery for obese adolescents and teens. Such interventions are supposed to be a last resort, but medicating children has become the go-to solution for common problems like anxiety and impulse control.
Intensive behavioral and lifestyle changes should be the first-line approach, but the AAP also includes recommendations for anti-obesity medications and surgery for the first time. The guidelines say that pediatricians should offer weight-loss drugs for children age 12 and up with obesity. She also acknowledged that these lifestyle changes can be really hard to adopt, especially for overworked and low-income parents. The more adverse the environment around you, the harder it is to live a healthy lifestyle,” Hassink said. Medications and surgery are expensive, and asking overstretched parents to implement lifestyle changes is not always realistic.
Pediatricians Recommend Weight-Loss Drugs for Obese Children
  + stars: | 2023-01-09 | by ( Sarah Toy | ) www.wsj.com   time to read: +1 min
Children 12 and older who are obese should be offered weight-loss medications alongside lifestyle and behavioral counseling, according to new American Academy of Pediatrics guidelines. The American Academy of Pediatrics for the first time recommended physicians offer weight-loss drugs for children with obesity, aiming to take early action against an increasingly common condition linked to a host of health problems. Children 12 or older who are obese should be offered medications for weight loss alongside lifestyle and behavioral counseling, according to guidelines published on Monday by the largest professional association of pediatricians in the U.S. The association also recommended that doctors offer to refer severely obese children 13 or older to surgeons to assess whether they would be good candidates for bariatric surgery. It said pediatricians should screen obese children for high cholesterol, diabetes and hypertension.
Metformin has been used off label to achieve weight loss in children. Of the 27 randomized trials of metformin for weight loss in children reviewed by the guidelines panel, 74% showed some positive effect of the medication. Wegovy last month won U.S. approval for chronic weight management in children ages 12 and older. For children ages 2 to 12 years, AAP said there was not currently enough evidence to recommend use of these medications. They also include recommendations for diagnosing obesity annually in children ages 6 years and older, through checks on BMI, and practices such as motivational interviewing.
Big Pharma will muscle in on obesity gold rush
  + stars: | 2022-11-28 | by ( Aimee Donnellan | ) www.reuters.com   time to read: +4 min
LONDON, Nov 28 (Reuters Breakingviews) - Obesity drugs are a modern day gold rush for drugmakers. By then, the obesity market could total $50 billion, according to Morgan Stanley. But a plausible 50% price cut would lower annual sales to $25 billion. Reuters GraphicsFollow @aimeedonnellan on TwitterCONTEXT NEWSSales of Novo Nordisk’s obesity drugs Wegovy and Saxenda reached nearly $1.2 billion in 2021, up 50% versus the previous year. Morgan Stanley analysts expect the obesity market to grow to $50 billion in annual sales by 2030.
A brain implant reduced two patients' binge eating for at least six months. The two patients were fitted with a brain implant to zap the part of the brain linked to cravings. The idea of targeting brain waves to fight cravings has been appealing, so much so that Elon Musk recently said his Neuralink brain implant could one day fight morbid obesity. The implant used in the study learned to recognize those brainwaves and zap that region with electricity to scramble them, which seemed to cut the cravings short. With just two patients, the scientists can't prove for sure that it was the implant causing the weight loss.
Now a wave of startups offer access to a new category of drugs coupled with intensive behavioral coaching online. These patients pay hundreds, if not thousands, of dollars, to access new drugs, called GLP-1 agonists, along with online coaching to encourage healthy habits. (That price includes generic drugs, but not the newer GLP-1 agonists, like Wegovy.) The firms say they’re on the vanguard of weight care, both citing the influence of biology and other scientific factors as key ingredients to their approaches. Found said older generics like zonisamide are more accessible than the GLP-1 agonists advertised on social media and their own website.
They are also increasingly being prescribed by doctors and covered by insurers – a win for patients and for investors. According to Novo Nordisk , the maker of weight-loss drug Wegovy, about 80% of anti-obesity medications are being covered by health insurers, Meacham said. Novo's semaglutide is branded Wegovy as a weight-loss treatment and Ozempic for the treatment of type 2 diabetes. When combined with lifestyle modifications, patients taking Wegovy can sustain a 15% weight loss , according to late-stage clinical trial data. Eli Lilly has a competing drug, Mounjaro, that uses both GLP-1 and a second incretin, glucose-dependent insulinotropic polypeptide, or GIP.
An earlier study in adults showed that the drug did indeed help with weight loss. “We’ve entered the phase where we are seeing the kind of weight loss where teens come to us in tears. In addition to the weight loss, the drug reduced some cardiovascular risk factors, including waist circumference and bad cholesterol. As it turns out, even when people get weight loss surgery, “three years out, there is significant weight gain,” Li said. When a weight loss drug like this is prescribed to patients, that shouldn’t be the end of things, Li said.
As a result, countries such as China and Japan have set lower BMI overweight and obesity thresholds for people of Asian descent. Experts generally agree that BMI should not be the only measure to assess patients’ health and weight. Instead of relying on BMI, physicians and patients should consider other factors in the weight equation. It incorporates various groups’ risk factors for conditions such as diabetes, high blood pressure, and high cholesterol. “We do not plan to eliminate the BMI, but we plan to devise other strategies to evaluate the health associated with weight status,” said Stanford.
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