Brent crude futures for April delivery were down $2.33, or 2.8%, to $80.72 a barrel at 2:20 p.m. EST (1920 GMT), while West Texas Intermediate (WTI) crude futures dropped by $2.31, or 3%, to $74.05 a barrel.
"While better U.S. economic data should mean better oil demand, the concern is that this forces the Fed to overtighten monetary policy to bring inflation under control," said UBS analyst Giovanni Staunovo.
Other U.S. economic reports, however, showed some troubling signs for the world's biggest oil consumer.
According to a preliminary Reuters poll on Tuesday, analysts forecast a rise in U.S. crude inventories, feeding demand worries.
Morgan Stanley raised its global oil demand growth estimate for this year by about 36%, citing growing momentum in China's reopening and a recovery in aviation.