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CNN —The US Food and Drug Administration approved the medication Zepbound last week to treat chronic obesity. Tirzepatide joins a similar medication called semaglutide that was also initially developed for diabetes treatment under the name Ozempic and has since been approved to treat obesity under the name Wegovy. Studies on both have shown high effectiveness in treating diabetes and obesity. The injectable medication Zepbound, manufactured by Eli Lilly, was approved by the FDA on November 8 to treat chronic obesity. Note that technically, the versions of the medicines someone needs for obesity treatment are Zepbound and Wegovy.
Persons: Eli Lilly, Tirzepatide, , Leana Wen, Wen, Zepbound, Ozempic Organizations: CNN, Food and Drug Administration, George Washington University Milken Institute School of Public Health, FDA, The New England, of Medicine, JAMA, Novo Nordisk, semaglutide, BMI Locations: The, tirzepatide, Wegovy
Psychological distress was assessed based on self-reported responses to a standardized set of questions about feelings and experiences. The 988 lifeline launched in July 2022, transitioning from the National Suicide Prevention Lifeline to a broader focus and a simpler dial code. As the US faces a significant mental health crisis, experts emphasize how critical a tool like the 988 lifeline is. Monica Johnson, director of the 988 & Behavioral Health Crisis Coordinating office, has called it “the most transformative initiative in behavioral health care” that she’s seen in her decades-long career. But getting it right on the lifeline – and after – will require better training of mental health professionals, the study authors said.
Persons: , Michael A, Lindsey, Monica Johnson, she’s, Jonathan Purtle, , Purtle, Dr, Sanjay Gupta, ” Lindsay, , ” Purtle Organizations: CNN, , New York University Silver School of Social, Prevention, US Department of Health, Human, Mental Health Services Administration, Behavioral, New York University School of Global Public Health, CNN Health
“Controlling blood sugar is more important for those with type 2 diabetes, but losing weight (specifically visceral fat) usually leads to better blood sugar control,” she added. However, there was no loss of lean muscle mass in the new study, Varady said. “I definitely lost weight when I did it,” said Weiss, who is affiliated with the Cardiovascular Research Institute at the University of California, San Francisco. Cavan Images/Cavan Images RF/Getty ImagesEveryone is differentThe best route to weight loss can differ from person to person, experts say, which is one reason why there are so many dietary options. Time-restricted eating is right for some, but not for others, Katz said.
Persons: , Krista Varady, Varady, ” Varady, , David Katz, Katz, ” Katz, Ethan Weiss, Weiss, ” Weiss, they’re Organizations: CNN —, University of Illinois, A1C, True Health Initiative, Cardiovascular Research, University of California Locations: University of Illinois Chicago, San Francisco, Cavan
In addition to a loss of overall body fat, participants in the study lost dangerous visceral belly fat, which could lead to diabetes, heart disease and stroke. If visceral fat is about 10% of your body’s total fat mass, that’s normal and healthy, according to the Cleveland Clinic. Too much visceral fat, however, can create inflammation, contributing to chronic disease. A lower-calorie Mediterranean diet could include proteins such as salmon, chicken breast and tuna, as well as fruits, vegetables, nuts, seeds, legumes and olive oil. However, “only participants from the intervention group decreased grams of visceral fat mass,” while visceral fat mass remained unchanged in the control group, according to the study.
Persons: , David Katz, Katz, Walter Willett, Harvard T.H, , Willett, Gunter Kuhnle, ” Kuhnle, Christopher Gardner, ” Gardner Organizations: CNN, True Health Initiative, Cleveland Clinic, Harvard, of Public Health, Harvard Medical School, JAMA, University of Reading, Stanford Prevention Research, Nutrition Studies Research Locations: Chan, Boston, Spain, United Kingdom, California
CNN —Eating greater amounts of ultraprocessed food and drinks, especially if those items are artificially sweetened, may be linked to the development of depression, according to a new study. Ultraprocessed foods include hot dogs, sausages, French fries, sodas, store-bought cookies, cakes, candies, ice cream and many foods containing artificial sweeteners. For one, there is a known link between ultraprocessed foods and chronic inflammation, Chan said. For example, studies have linked ultraprocessed foods colorectal cancer in men and heart disease and early death in both men and women. In addition, the study is observational, which means that researchers can only find an association between the onset of depression and the intake of ultraprocessed foods.
Persons: ” Gunter Kuhnle, , Andrew T Chan, Daniel K, Harvard T.H, Chan, Kuhnle, ” Marion Nestle, Paulette Goddard, ” Chan, David Katz, ” Katz, ” It’s, Katz, It’s, Paul Keedwell, Keith Frayn, Frayn, ” Frayn Organizations: CNN, University of Reading, Harvard Medical School, Harvard, of Public Health, Massachusetts General Hospital, New York University, ” Association, JAMA, Nurses, True Health Initiative, Royal College of Psychiatrists, BMI, University of Oxford Locations: Chan, Boston, Massachusetts, McDonald’s
Menopause is considered early when it occurs before age 45, which will happen in 5% to 10% of women, Yang said. Early menopause is concerning because of the shortened reproductive years, but also because of links to other health concerns, she added. A 2010 study found that women who experience early menopause are at an increased risk for overall mortality, including cardiovascular diseases, osteoporosis and neurological diseases. How are PMS and early menopause connected? Women also need to know that there are ways to manage early menopause and the bothersome hot flashes, she said.
Persons: , Yihui Yang, Yang, Stephanie Faubion, Faubion, , Donghao Lu, ” Faubion, Elizabeth Bertone, Johnson, Organizations: CNN, Karolinska Institutet, Mayo Clinic Center, Women’s Health, PMDs, Karolinska, University of Massachusetts Amherst, American College of Obstetricians, Women’s, US Department of Health, Human Services Locations: Sweden
CNN —A person’s sense of purpose declines leading up to and following a diagnosis of dementia or cognitive decline, according to a new study. “Purpose in life is the feeling that one’s life is goal-oriented and has direction. “Purpose may be an intervention target following cognitive impairment to maintain well-being and to reduce or slow emergence of behavioral symptoms associated with low purpose,” the study said. But it is critically important for everyone to maintain a sense of purpose later in life, Sutin said. “The opposite of purpose in life — apathy — is a significant problem in dementia.
Persons: , Angelina Sutin, Sutin, Sam Fazio, , Fazio, ” Fazio, , ’ ” Fazio Organizations: CNN, JAMA, Florida State University College of Medicine, National Health, Alzheimer’s Association Locations: Tallahassee
Documented marijuana-related traffic accidents that required treatment in an emergency room rose 475% between 2010 and 2021, the study found. Just after Canadian legalization in 2018, when marijuana stores and products were limited, researchers found a 94% increase in emergency room visits, Myran said. Car crashes involving weed were serious. Another issue is the rising potency of cannabis, Myran said. Canada’s lower-risk cannabis guidelines recommend not driving for at least 6 hours after using cannabis and avoiding cannabis and alcohol together.
Persons: , Daniel Myran, Myran, Marco Solmi, ” Myran, , Solmi, , ” Solmi, Robert Page II, Page, I’m, ” Page Organizations: CNN, University of Ottawa, Ottawa Hospital Research Institute, JAMA, Traffic, NHTSA, Research, Highway, Transportation Safety Administration Locations: Canada, United States, Colorado
But now, two studies released Tuesday suggest that a recently developed eye-tracking tool could help clinicians diagnose children as young as 16 months with autism – and with more certainty. She was not involved in the new studies, but her research focuses on early diagnosis of autism. The children were enrolled in the study between April 2018 and May 2019, and the eye-tracking tool was included in the assessments. Among the children, 335 had an autism diagnosis that their clinicians were “certain” of without using the eye-tracking tool. “There remains work to be done before an eye-tracking test is used in clinical practice.
Persons: , Warren Jones, Rather, , Whitney Guthrie, Guthrie, “ They’re, ” Jones, , Ami Klin, Marcus, ” Klin, Kristin Sohl, ” Sohl, Sohl, Dr, Sanjay Gupta, Geraldine Dawson, , ” Dawson Organizations: CNN, Marcus Autism, Children’s Healthcare, Autism, Emory University School of Medicine, US Food and Drug Administration, Children’s, Philadelphia’s Center, Autism Research, JAMA, Marcus Autism Center, University of Missouri School of Medicine, American Academy of Pediatrics, US Centers for Disease Control, Devices, Get CNN, CNN Health, Duke Center for Autism, Brain Locations: Atlanta, United States, , North Carolina
The NewsMore than one-fifth of people who use cannabis struggle with dependency or problematic use, according to a study published on Tuesday in The Journal of the American Medical Association Network Open. The research found that 21 percent of people in the study had some degree of cannabis use disorder, which clinicians characterize broadly as problematic use of cannabis that leads to a variety of symptoms, such as recurrent social and occupational problems, indicating impairment and distress. In the study, 6.5 percent of users suffered moderate to severe disorder. Cannabis users who experience more severe dependency tended to be recreational users, whereas less severe but still problematic use was associated roughly equally with medical and recreational use. The most common symptoms among both groups were increased tolerance, craving, and uncontrolled escalation of cannabis use.
Organizations: American Medical Association Network
CNN —Developing cannabis use disorder is relatively common in Washington state, one of the first states to fully legalize cannabis, and can even occur in people who only use medical marijuana, according to a new study. “There’s a perception that people who are using marijuana for medical reasons have a lower risk of a cannabis use disorder,” said lead author Gwen Lapham, assistant professor at Kaiser Permanente Bernard J. Tyson School of Medicine in Seattle. In addition, using both medical and recreational weed led to a more severe addiction than using medical marijuana alone, the study revealed. There are no current FDA-approved medications to treat cannabis use disorder, Lapham said, so behavior-based treatments or specialty addiction centers are the rule. A 2021 study found cannabis use disorder rose from 17.7% before marijuana was legalized in Canada to 24.3% after legalization.
Persons: , , Gwen Lapham, Kaiser Permanente Bernard J, Lapham, Nicholas Vozoris, Alexandre Dumais, ” Dumais, Dumais, It’s, Beth Cohen Organizations: CNN, Kaiser Permanente, Tyson School of Medicine, US Centers for Disease Control, Kaiser Permanente Washington Health Research, University of Toronto, University of Montreal, FDA, University of California Locations: Washington, Seattle, respirology, Washington State, Netherlands, Germany, Australia, New Zealand, Ireland, France, Canada, San Francisco
The study by the federally funded Fred Hutchinson Cancer Center in Seattle was taken from a sample of mortality data published by some universities in China and internet searches. It found an estimated 1.87 million excess deaths from all causes occurred among people over 30 years of age between December 2022 and January 2023, and were observed in all provinces in mainland China except Tibet. In the study, researchers performed statistical analysis using information from published obituaries and data from searches on Baidu, a popular Chinese internet search engine. "Our study of excess deaths related to the lifting of the zero-COVID policy in China sets an empirically derived benchmark estimate. The World Health Organization says there have been 121,628 COVID deaths in China, out of a total global toll of almost 7 million.
Persons: Thomas Peter, cremations, China's, COVID, Bernard Orr, Lincoln Organizations: REUTERS, Rights, Fred Hutchinson Cancer Center, Baidu, Health Commission, Global, World Health Organization, National Bureau of Disease Control, Prevention, Global Times, Thomson Locations: Beijing, China, Rights BEIJING, U.S, Seattle, Tibet
Pulse oximeter readings are used routinely and help inform doctors in shaping medical care for any number of illnesses, including heart failure, sleep apnea and respiratory conditions. If the readings are falsely high, patients may look fine on paper — but they may not get the level of care they need. Black patients were found to be nearly 50 percent more likely than white patients to have their condition go undetected. Hispanic patients were 18 percent more likely than white patients to have an unrecognized need. Patients with unrecognized needs, regardless of race, experienced delays of roughly an hour that translated into a 10 percent higher risk of delayed Covid treatment.
Persons: , , Ashraf Fawzy, Johns Hopkins, Fawzy Organizations: Drug Administration
CNN —Mothers who followed the Mediterranean diet while pregnant improved their children’s cognitive, social and emotional development at age 2 compared with children whose mothers did not follow the diet, according to a new randomized clinical trial. “No other dietary model possesses such an impressive accrual of scientific evidence as the traditional Mediterranean diet,” said Martínez-González, who is also an adjunct professor of nutrition at the Harvard T.H. The number of low-weight births dropped to 15.6% of the women who attended stress-reduction classes and 14% of the women who ate a Mediterranean diet. The Mediterranean diet focuses on fruits, vegetables, whole grains, beans and seeds, with a few nuts and a heavy emphasis on extra-virgin olive oil. “The first arm (Mediterranean diet) addressed a more physical and direct aspect: the dietary pattern and the supply of interesting nutrients that are known to be beneficial.
Persons: CNN —, , , Miguel Martínez, David Katz, ” Katz, nutritionists, Bayley, Katz, González Organizations: CNN, University of Navarra, Harvard, of Public Health, True Health Initiative Locations: Pamplona, Spain, Chan, Boston, Barcelona
The study found that overall, early-onset cancers increased over that decade, by an average of 0.28% each year. There were 34,233 early-onset cancer cases in women in 2010 and 35,721 in 2019, an increase of 4.35%, the study says. The rate of cancer diagnosis increased in adults in their 30s over the decade but remained stable in other under-50 age groups, the study found. Cancers with the highest numbers of early-onset cases­ diagnosed in 2019 were breast (12,649 cases), thyroid (5,869) and colorectal cancers (4,097). Previous research has shown a rise in cancers of the digestive system, particularly colorectal cancers, among adults younger than 55 since the 1990s.
Persons: Otis Brawley, Dr, Sanjay Gupta, , , “ There’s, Brawley, John Bonifield Organizations: CNN, National Cancer Institute, JAMA, Bloomberg, Oncology, Johns Hopkins University, CNN Health Locations: Alaska Natives, Black, United States
Though it is still unclear which 10 drugs Medicare will select, several pharmaceutical companies have already revealed in court filings that they expect four of their blockbuster medications to be targeted. Bristol-Myers Squibb and Johnson & Johnson , in separate filings, said their blood thinners Eliquis and Xarelto will be subject to the negotiations this year. The list price of Januvia has surged 275% since 2006, according to the AARP. Johnson & Johnson reported $2.47 billion in revenue from Xarelto. "More and more people face cost-sharing that is directly affected by drug price increases," Leigh Purvis, who analyzes health-care costs for AARP, told reporters on a call Thursday.
Persons: Daniel Acker, Merck, Johnson, Abbvie, Imbruvica, Jardiance, Boehringer Ingelheim, Amgen Symbicort, Pfizer Xtandi, Breo, Biden, Januvia, Eliquis, Xarelto, Leigh Purvis Organizations: Merck, Co, Inc, Bloomberg, Getty, Medicare, Services, Myers Squibb, Johnson, Pharmacy, AstraZeneca Ibrance, Pfizer, Astellas Pharma, GSK, AARP, Bristol Myers Squibb, Jama Network, Industry Locations: Bristol, U.S, Januvia, Xarelto
Nairobi, Kenya CNN —Former employees of Twitter Africa who were laid off as part of a global cost-cutting measure after Elon Musk’s acquisition have not received any severance pay more than seven months since leaving the company, several sources told CNN. “They literally ghosted us,” one former Twitter Africa employee told CNN. Twitter and Musk face multiple lawsuits where plaintiffs are claiming the company has failed to pay former staffers what they are owed. The plaintiff said Twitter promised senior employees severance of six months of base pay plus one week for every year of service, in addition to other benefits. “We’re exploring our options with respect to causes of action against Twitter in various jurisdictions including Ghana,” Olympio told CNN.
Persons: , , Carla Olympio, Musk, Ghana’s, ” Olympio, Twitter, David Odisho Organizations: Kenya CNN —, Twitter, Elon, CNN, Ghana’s Ministry of Employment, Labor Relations, BBC Locations: Nairobi, Kenya, Twitter Africa, Accra, Africa, Ghana, San Francisco , California, Europe, North America
The Tesla Supercharger network could remove the last barrier to EV ownership. Long-standing barriers to EV ownership like battery range and price are finally being addressed, leaving one last obstacle for many would-be EV-owners: access to public fast-charging stations. Tesla has the largest fast-charging network in North America, with about 20,000 Superchargers that previously only connected to Tesla vehicles. A recent study of EV infrastructure done by iSeeCars found that of the 150,000 EV chargers in the US, only about 30,000 are fast chargers (including the Tesla Supercharger network). Only about 11,000 of those fast chargers are non-Tesla chargers so opening up the Supercharger network does make a difference – but doesn't solve the problem.
Persons: Tesla, Long, Karl Brauer, We've, Brauer, iSeeCars, Rivian, Dan Ives Organizations: EV, Morning, Ford, GM, Tesla EV, Tesla Locations: North America
Capital One Venture X credit card review
  + stars: | 2023-06-13 | by ( ) edition.cnn.com   time to read: +19 min
Digging into the Capital One Venture XThe Capital One Venture X provides valuable benefits to frequent flyers. Getty ImagesThe Capital One Venture X credit card debuted in November 2021 and turned of heads for those looking for a premium travel rewards credit card. Advantages of the Capital One Venture XEarn miles toward a beautiful beach vacation with the Capital One Venture X. iStockAs a new premium credit card, the Capital One Venture X has a lot to offer. Stacking up the Capital One Venture X against our benchmarkCNN Underscored has chosen the Citi Double Cash card as our current “benchmark” credit card. Other credit cards similar to the Capital One Venture XCompare the Capital One Venture X to other premium travel credit cards before you apply.
Persons: that’s, you’ll, — you’ll, Air Canada Aeroplan, That’s, you’re, Guy, Emily McNutt Organizations: CNN, American Express, Capital, Venture, PreCheck, Fort, Dulles, Hertz President’s, British Airways, Airlines Aeromexico Club Premier Cathay Pacific Asia Miles Qantas Frequent Flyer Air Canada, Emirates Skywards Singapore Airlines KrisFlyer Air France, KLM Flying Blue Etihad Airways, TAP Air Portugal Miles, Airlines Miles & Smiles British Airways Avios, Wyndham, British Airways Executive Club, Air Canada, United Airlines, Emirates, Singapore Airlines, Citi, Cash, Citi Premier, Accident Insurance, Chase, Express, Chase Sapphire, Rapid, Hyatt Locations: Dallas, Fort Worth, DFW, Denver, Washington, American, Alaska, Asia, Europe, Chicago
And regulators could help monitor that such responses offer accurate and reliable information and resources. They’re underutilized already,” said John Ayers, an author of the study and a behavioral scientist at the University of California, San Diego. He said that now, while ChatGPT is still in development, is the time for public health experts and regulators to join forces with the chatbot’s developers to help curate responses to medical questions. The chatbot provided resources in two responses to a question about addiction, two responses for questions related to interpersonal violence and one response to a mental health-related question. “ChatGPT consistently provided evidence-based answers to public health questions, although it primarily offered advice rather than referrals,” the researchers wrote in their study.
Persons: They’re underutilized, , John Ayers, ChatGPT, , , ” Ayers, ” ChatGPT, “ ChatGPT, Ayers, Dr, Mike Hogarth, Sanjay Gupta, David Asch, Asch, ” Asch, he’d, Deidre McPhillips Organizations: CNN, JAMA, University of California, UC San Diego, Anonymous, Mental Health Services Administration National, Prevention, UC San Diego School of Medicine, Eating Disorders Association, CNN Health, University of Pennsylvania, Penn Medicine Center, Health Care Innovation Locations: San Diego, United States
Experiencing negative changes in workplace leadership and fairness was associated with the strongest long-term impact on a worker's sleep. LumiNola/E+/Getty ImagesSleep problems included initiating or maintaining sleep, poor-quality sleep and daytime tiredness two to four times a week that lasted one month to three months. Within a two-year period of time, over half of the participants (53%) reported changes in their workplace environment. However, if the changes at work were negative, sleep issues increased — in fact 1 in 4 people in the study with a worse job environment developed problems getting enough rest. Having negative changes in the leadership and fairness sector was associated with the greatest long-term impact on sleep, more than negative changes in coworker relationships or collaboration, the study found.
How promising are new drugs to treat obesity?
  + stars: | 2023-05-05 | by ( Katia Hetter | ) edition.cnn.com   time to read: +8 min
CNN —The pharmaceutical company Eli Lilly announced last week that a medication developed to treat diabetes, tirzepatide, also had a substantial effect on reducing weight. Another pharmaceutical company, Novo Nordisk, manufactures the medication semaglutide, which the FDA has already approved to treat diabetes under the brand name Ozempic and to treat obesity under the brand name Wegovy. How promising are they to treat obesity? CNN: How promising are these drugs to treat obesity? It is really important to treat obesity as the disease that it is — and having effective medications to do so is crucial.
Vaping involves heating a liquid that contains nicotine in an e-cigarette which is vaporized and inhaled by the user. “Vaping was sold to governments and communities around the world as a therapeutic product to help long-term smokers quit,” Butler said. “It was not sold as a recreational product – in particular not one for our kids. Vaping concerns across the worldResearchers have found links between nicotine addiction among adolescents and children as a result of increased vaping habits. Meanwhile, the United Kingdom is also tackling high-levels of youth vaping but is pushing it as an alternative to help long-term smokers quit.
CNN —The outbreak of Covid-19 presented many dangers for children, and a new study suggests increased illicit substance ingestions were among them. Those numbers grew by 1.8% more per month than they did before the pandemic, the study said. The results could be skewed if health care providers were on the lookout for ingestions, Dodington added. There was no association between medicinal or recreational cannabis legalization and the rate of cannabis ingestion encounters, according to the study. Safer storageIngesting drugs and alcohol are particularly dangerous for young children, Dodington said.
CNN —A new study on breast cancer deaths raises questions around whether Black women should screen at earlier ages. Even though Black women have a 4% lower incidence rate of breast cancer than White women, they have a 40% higher breast cancer death rate. “When the breast cancer mortality rate for Black women in their 40s is 27 deaths per 100,000 person-years, this means 27 out of every 100,000 Black women aged 40-49 in the US die of breast cancer during one year of follow-up. They also wrote that health policy makers should pursue equity, not just equality, when it comes to breast cancer screening as a tool to help reduce breast cancer death rates. Having dense tissue in the breast can make it more difficult for radiologists to identify breast cancer on a mammogram, and women with dense breast tissue have a higher risk of breast cancer.
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