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It was shown in May and in fuller Phase 3 clinical trial results released at the Alzheimer’s Association International Conference on Monday to delay the disease’s progression. More than 6 million Americans are estimated to have Alzheimer’s disease, with about 1 million estimated to be in the early symptomatic stages where these drugs have shown benefit. Both Leqembi and donanemab work by clearing buildups of a protein in the brain called amyloid, a hallmark of Alzheimer’s. It’s been a hypothesis that treating Alzheimer’s earlier with amyloid-clearing drugs would yield better results; Skovronsky said the donanemab trial bore that out. “We could look at people who had mild cognitive impairment, MCI, which is the earliest stage, versus mild Alzheimer’s versus moderate Alzheimer’s,” Skovronsky explained.
Persons: Leqembi, Eli Lilly’s donanemab, Lilly, “ Donanemab, Jennifer Manly, Kacie, , Dr, Gil Rabinovici, Renaud La Joie, Daniel Skovronsky, , Skovronsky, ” Skovronsky, It’s, Eric Widera, Sharon Brangman, University of Wisconsin’s Dr, Nathaniel Chin, Donanemab, Lilly hasn’t, Lawrence Honig, Honig, White, Sanjay Gupta, Deters, ” Lilly, it’s “, it’s, there’s, Joe Montminy Organizations: CNN, Alzheimer’s Association, Food and Drug Administration, American Medical Association, Columbia University Irving Medical Center, University of California, MCI, SUNY, University of Wisconsin’s, Leqembi, FDA, donanemab, CNN Health, ” Manly Locations: Los Angeles,
CNN —The US Food and Drug Administration is expected to decide on Thursday whether to grant traditional approval to the Alzheimer’s drug Leqembi, the first medicine proven to slow the course of the memory-robbing disease. Leqembi, from drugmakers Eisai and Biogen, received accelerated approval in January based on evidence that it clears amyloid plaque buildups in the brain that are associated with Alzheimer’s disease. But because of an earlier coverage decision by CMS, which provides insurance coverage for many elderly patients with Alzheimer’s through Medicare, the drug hasn’t been widely used. People with more advanced forms of the disease may not benefit from the drug, he said, and may face increased safety risks. Broad Medicare coverage of Leqembi and similar types of medications to slow the progression of Alzheimer’s disease would probably have a big impact on the program’s spending.
Persons: drugmakers, hasn’t, , ’ ”, Joe Montminy, Lawrence Honig, “ It’s, , Honig, it’s, Leqembi, ” Honig, Georges Naasan, Sue Rottura, ” Drugmaker Eisai, “ You’re, Ivan Cheung, Eisai, ” Montminy, Dr, Sanjay Gupta Organizations: CNN, Food and Drug Administration, Medicare, Services, CMS, Columbia University Irving Medical Center, Alzheimer’s, Behavioral, CNN Health, Kaiser Family Foundation Locations: Mount, Florida
CNN —Critics on Tuesday seized on the latest Trump tape as a perfect example of why the twice-impeached, twice-indicted former president is unfit to return to the Oval Office. On the audio – exclusively obtained by CNN – Trump discusses holding a secret document. In the tape, Trump seems to indicate he was holding up information that may be among the government’s most closely guarded secrets. As he often did in office, Trump appears to have been using US national security as a tool for his own personal or political gain. In response to the tape, Trump – as he often does – sought to redefine an apparent example of aberrant behavior as perfectly acceptable.
Persons: CNN – Trump, Trump, “ We’ve, Liz Cheney, NBC’s Lester Holt, Elie Honig, Donald Trump, ” Honig, , Adam Kinzinger, Cheney, , ” Trump, he’s, Kevin McCarthy –, CNN’s Kristen Holmes, Breitbart, , Fox, Volodymyr Zelensky, Joe Biden, Trump’s, I’m, Rudy Giuliani, Nikki Haley, Jack Smith, Haley didn’t, “ We’re Organizations: CNN, Trump, GOP, Wyoming, Aspen Ideas, CNBC, California Republican, Breitbart News, , Fox News Digital, weaponized Justice Department, New Hampshire Federation, Republican, NBC News, Republicans, New Hampshire Republican, Justice Department, Biden’s, Former South Carolina Gov Locations: Washington, Bedminster , New Jersey, United States, Illinois, California, Florida, Georgia, New Hampshire, Manhattan
Noah Gray, CNN’s senior coordinating producer for special events, had grown up in the Miami area and attended Palmetto Senior High School. The remarkable effort to report on the court proceeding was only necessary because of the archaic system in which U.S. federal courts operate. The public continues to have remarkably little access to proceedings in federal courts — no matter how consequential or extraordinary the case may be. Generally speaking, federal courts refuse to budge. “I think the benefits for public access cut for both Trump and the prosecution,” Katyal told Nicolle Wallace.
Persons: Donald Trump, Trump, Noah Gray, CNN’s, Tierney Sneed, Hannah Rabinowitz, Sneed, Rabinowitz jotted, Brad Parks, ” Gray, ” Elie Honig, Jake Tapper, ” Honig, , Neal Katyal, Katyal, ” Katyal, Nicolle Wallace, newsrooms Organizations: CNN, Palmetto Senior High School, MSNBC, Trump Locations: Miami, Washington, D.C
Donald Trump’s criminal cases, explained
  + stars: | 2023-06-09 | by ( Zachary B. Wolf | ) edition.cnn.com   time to read: +14 min
Trump was indicted back in March by the Manhattan district attorney on state charges related to hush-money payments to a former adult-film star in 2016. Smith is also overseeing other investigations related to Trump, including those regarding the January 6, 2021, insurrection and the 2020 election. That federal law deals with the illegal retention of “national defense information,” a broad term that encompasses classified documents and other sensitive government materials. Federal charges related to classified documents likely do not either. But people do routinely serve prison time for retention of classified documents, conspiracy and obstruction.
Persons: Donald Trump’s, He’s, Jack Smith, Trump’s, Trump, Aaron Burr, Wasn’t, isn’t Trump, Smith, Joe Biden’s, Jim Trusty, , Elie Honig, CNN’s Marshall Cohen, CNN’s Evan Perez, Joe Biden, Honig, , Robert Ray, Ray, it’s, David Axelrod, ‘ They’re, , Richard Hasen, don’t, Jean Carroll, We’re, hasn’t, Hasen, Richard Nixon, Gerald Ford, Nixon’s, Spiro Agnew, Agnew, Burr, We’ve, Let’s Organizations: CNN, US Department of Justice, Trump, White, National Archives, Prosecutors, Lago, USC, FBI, DOJ, That’s, Manhattan, Justice Department, Republican, Democratic, University of California, Senate, State, Quinnipiac University, Service Locations: Lago, Miami, Manhattan, Florida, Trump . Miami, Washington, New York, Dade County, Los Angeles, United States, New York City, Fulton County , Georgia, York
Most people recall the “Access Hollywood” tape of Trump using vulgar language to argue that “stars” can grab women. It also adds his Bedminster club to the potential locations where Trump had classified documents after leaving office. In response to the report, a Trump campaign spokesman said “leaks” are meant to “inflame tensions” around Trump. (The document Trump references was not produced by Milley, CNN was told.) Besides the ongoing investigations into the aftermath of the 2020 election, here’s what else is looming over Trump.
Persons: Donald Trump’s, Trump, Joe Biden’s, Jack Smith, who’s, , Elie Honig, Jake Tapper, ” Trump, undercuts, Smith, CNN’s Katelyn Polantz, Paula Reid, Kaitlan Collins, Mark Milley, Susan Glasser, Milley, CNN’s Haley Britzky, ” Beth Sanner, , CNN’s Kaitlan Collins Organizations: CNN, GOP, Trump, Department of Justice, ” CNN, Joint Chiefs, Staff, Milley, Chiefs, National Intelligence Locations: New York, Georgia, Peach State, Bedminster, Trump, Iran, Milley, New Hampshire
The recording indicates Trump understood he retained classified material after leaving the White House, according to multiple sources familiar with the investigation. Meadows didn’t attend the meeting, sources said. The revelation that the former president and commander-in-chief has been captured on tape discussing a classified document could raise his legal exposure as he continues his third bid for the White House. On the recording and in response to the story, Trump brings up the document, which he says came from Milley. However, there’s no indication Trump followed the legally mandated declassification process, and his attorneys have avoided saying so far in court whether Trump declassified records he kept.
Persons: Donald Trump, Trump, Jack Smith, Mark Milley, Trump’s, Mark Meadows, Margo Martin, Meadows, Trump “, , Dave Butler, Martin, Olivier Douliery, Susan Glasser, Milley, Glasser, ” Milley, Honig, They’ve Organizations: CNN, Federal, White, Justice Department, Trump, Prosecutors, Joint Chiefs, Staff, Milley, Capitol, Getty, Yorker, National Archives, Records Administration, The Justice, Lago, Office, Fox News Locations: Iran, Bedminster , New Jersey, Washington ,, AFP, New, Milley, Lago, Florida, Bedminster, Trump
The special counsel was looking into whether any crimes occurred in the handling of an uncorroborated piece of US intelligence indicating Russia knew of a Clinton campaign plan to vilify her opponent, Trump, by tying him to the country. During the Trump administration, Director of National Intelligence John Ratcliffe released some of Brennan’s notes about the intelligence used in his briefing of former President Barack Obama. Ratcliffe publicly said that the intelligence community never corroborated the Russian claims of a “Clinton Plan” to frame Trump, and didn’t know whether it was fabricated. In her interview with Durham’s investigators, Clinton expressed sympathy for Durham’s hunt. Durham concludes that it would be impossible to prosecute anyone for their handling of the intelligence.
The first scene of his reelection announcement video released last month showed smoke rising over the US Capitol and rioters with Trump flags. The legal complications facing Trump and GarlandGiven the fraught situation, the Justice Department’s next moves will be hugely significant. Thursday’s Proud Boys convictions are among the most significant of hundreds of successful Justice Department prosecutions of people linked to the US Capitol riot. So while a prosecution of Trump and his closest political associates over January 6 could be tough, it may not be impossible. So for now, at least with GOP primary voters, what doesn’t convict Trump, makes him stronger.
Smith takes over a staff that’s already nearly twice the size of Robert Mueller’s team of lawyers who worked on the Russia probe. Smith will also take on national security investigators already working the probe into the potential mishandling of federal records taken to Mar-a-Lago after Trump left the White House. Those lawyers maintain the former president is unlikely to be indicted, according to two sources familiar. Special Counsel Robert Mueller makes a statement about the Russia investigation on May 29, 2019 at the Justice Department in Washington, DC. Trump allies have consistently maintained that nothing Trump did related to the election and January 6 itself amounts to a crime.
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Trump on Saturday floated the "termination" of the Constitution over his 2020 election claims. Ex-federal prosecutor and CNN legal analyst Elie Honig called the comments "wrong" and "dangerous." A Massive Fraud of this type and magnitude allows for the termination of all rules, regulations, and articles, even those found in the Constitution," Trump wrote. I'll just summarize in response to Donald Trump's statement to say that virtually every word of that statement is wrong, crazy, and dangerous. The Department of Justice is currently investigating Trump's efforts to remain in office after his 2020 election loss to now-President Joe Biden.
CNN senior legal analyst and former federal prosecutor Elie Honig reacts to former President Donald Trump's statement on his social media platform Truth Social.
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The special master in the Mar-a-Lago case has asked Trump's lawyers to back up some of his claims. CNN's legal analyst saw this as a test of whether they were prepared to lie for him in court. Trump's lawyers have argued that defending his declassification claims at this stage could damage their defense in a potential trial, drawing an unimpressed response from Dearie. Trump's legal team spent weeks persuading federal court judge Aileen Cannon to appoint a special master to review the documents, a move that stalled the FBI's investigation and which the Department of Justice opposed. The special master has until November 30 to complete the review of the documents, and will hand back to Trump any that are shielded under executive privilege rules.
Mark Verlan s-a stins din viață la sfârșit de decembrie, pe crucea sa stă inscripăționată data de 26.12.2020. Opera de artă a lui Verlan reprezintă un amestec aproape paradoxal de conceptualism, performance, postmodernism, artă naivă și suprarealism. Mark Verlan este un artist care iubește să experimenteze. În 2003, Mark Verlan a participat în expoziția „Blut und Honig“, de la The Essl Collection (Viena), îngrijită de cunoscutul curator Herald Szeemann iar, în 2011, a reprezentat Republica Moldova la Bienala de la Veneția. În 2019 și 2020 a expus la București, Galeria Posibilă, și la Iași, Galeria Artep”, scrie Jurnalul.ro.
Persons: Mark Verlan, Mark, Victoria Nagy Vajda, Verlan, Szeemann Locations: România, Moldova, Chișinău, Republicii Moldova, Viena, Republica Moldova, Veneția, Austria, Germania, Italia, Olanda, Suedia, SUA, București, Iași
Умер молдавский художник Марк Верлан
  + stars: | 2021-01-03 | by ( ) ru.diez.md   time to read: +1 min
Умер молдавский художник-нонконформист Марк Верлан. Марк Верлан, известный как Мариока Сын Дождя, родился в 1963 году. «Марк Верлан был самым ярким и известным художником-нонконформистом из Кишинева. Марк Верлан был художником-экспериментатором. На странице Марка Верлана в Facebook опубликована информация для тех, кто хочет оказать помощь родственникам и близким художника.
Persons: Herald Szeemann, , Марк Верлан, Мариока Сын Дождь, Верлан Organizations: Facebook, Herald Locations: Вена, Республика Молдова, Австрия, Германия, Италия, Нидерландах, Румыния, Швеция, США, Кишинев, Армянское кладбище
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