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☆ This little-known genome editing stock is poised to surge more than 60%, JPMorgan says
▼ + stars: | 2024-01-29 | by ( Pia Singh | ) www.cnbc.com time to read: +3 min

JPMorgan thinks investors should flock to biotechnology company Beam Therapeutics , which the firm says stands to benefit from increased market share and a strong gene therapy pipeline. "We see BEAM outperforming our coverage over the mid-term, with current levels being an attractive entry point," the analyst said. The stock is down more than 4% so far this year, and has lost more than 42% over the past 12 months. BEAM 1Y mountain Beam stock. He added that BEAM-302 is "uniquely positioned" as a one-time genetic medicine for AATD, particularly given its success in preclinical trials.

Persons: Eric Joseph, Joseph Organizations: Beam Therapeutics, TAM Locations: U.S, 1H24

☆ Ancient human DNA suggests Columbus may not have brought syphilis to Europe after all
▼ + stars: | 2024-01-25 | by ( Marianne Guenot | ) www.businessinsider.com time to read: +7 min

Read previewThe idea that Christopher Colombus brought back syphilis from the New World might be completely wrong. Interim Archives/Getty ImagesThe timing of the arrival of syphilis in Europe is suspiciousLooking at historical literature, you would think syphilis definitely arrived with the conquistadors. There was a big outbreak of syphilis in Europe in the late 1400s, mostly in harbor towns, seemingly out of the blue. AdvertisementThis suggests that the bones lesions alone don't guarantee that syphilis was present in South America before Columbus, poking holes in the evidence used to support the hypothesis. AdvertisementWith this ancient genome, Schünemann and colleagues were able to discover that the whole Treponema family is much older than had ever been expected.

Persons: —, Christopher Colombus, didn't, Verena Schünemann, Christopher Columbus, Columbus, Brenda Baker, Schünemann Organizations: Service, Business, University of Basel, Arizona State University, Getty Locations: Europe, South America, Barcelona, Spain, Brazil, Asia, Japan, Columbus, India, Americas

☆ Did syphilis originate in the Americas? Ancient DNA offers some insight
▼ + stars: | 2024-01-24 | by ( Katie Hunt | ) edition.cnn.com time to read: +8 min

In France, it was named the “Neapolitan disease” after the French army got infected during its invasion of Naples, Italy, in the first documented syphilis epidemic. A complex disease caused by a complex bacteriumWithout treatment, syphilis can cause physical disfigurement, blindness and mental impairment. Others believe T. pallidum bacteria always had a global distribution but perhaps grew in virulence after initially manifesting as a mild disease. Some bones had marks characteristic of infection with T. pallidum — the bacteria effectively eat away at bones, leaving concave lesions. “The modern tools available for extracting DNA from ancient samples, for enriching the treponemal DNA, and obtaining deep sequencing from samples has rapidly increased our understanding of the Treponema.”

Persons: Christopher Columbus, Treponema pallidum, ”, Brenda J, Baker, Jose Filippini It’s, Molly Zuckerman, wasn’t, ” Zuckerman, “, it’s, Columbus, Europe ’, Sheila A, pallidum, Verena Schünemann, Schünemann, Mathew Beale, Beale, ” Lukehart Organizations: CNN, Research, Arizona State University, Bioarchaeology Laboratories, Mississippi State University, University of Washington, University of Zurich’s Institute of Evolutionary, Wellcome Sanger, Columbus Locations: France, Naples, Italy, Europe, Americas, Brazil, New, Laguna, Santa Catarina, Africa, Columbus, Finland, Estonia, Netherlands, Asia, Cambridge, England

☆ The Ancient Back Story of the Slimiest Animal in the Sea
▼ + stars: | 2024-01-16 | by ( Veronique Greenwood | ) www.nytimes.com time to read: +1 min

The hagfish, a deep-sea scavenger about the size and shape of a tube sock, has the curious ability to smother itself in its own snot. The mucus is a defense mechanism, released into the water (or in one unfortunate incident, all over an Oregon highway) when the fish feels threatened. A shark trying to take a bite of a hagfish will find itself suddenly unable to breathe, its gills clogged with the slime. “We have to be removing the mucus all the time on the ship, or they will die,” he said. The hagfish has no jaw, making it part of a group that diverged long ago from the ancestors of jawed vertebrates like ourselves.

Persons: Juan Pascual, Anaya, ” Organizations: University of Málaga Locations: smother, Oregon, Spain, Japan

☆ AI is helping the healthcare industry and could transform the way patients get drugs and treatments
▼ + stars: | 2023-12-22 | by ( Nicholas Fearn | ) www.businessinsider.com time to read: +10 min

In the pharmaceutical industry, AI may one day accelerate new-drug development. In the foreseeable future, McClain expects the healthcare industry to use AI technology to design personalized medicines. Risks to considerWhile AI offers promise for the healthcare industry, there are also a variety of risks professionals using AI must consider and mitigate. Showalter said that a lack of "comprehensive regulations" can also make using AI technology in healthcare settings risky. With this in mind, he said, the medical industry must understand the "fundamentals of AI and its applications in healthcare."

Persons: —, Sean McClain, McClain, Tim Showalter, Showalter, it's, Fred, haven't, Surya Josyula, Josyula Organizations: Experts, Service, Northwestern Medicine, Fred Hutchinson Cancer Center, UW Medicine, University of California, Fujitsu, Aichi Cancer, Fujitsu Laboratories of America Locations: University of California San Diego, Nagoya, Japan, China, United States

☆ Reproductive startup launches test to identify an embryo's genetic defects before an IVF pregnancy begins
▼ + stars: | 2023-12-05 | by ( Ashley Capoot | In | ) www.cnbc.com time to read: +2 min

Reproductive technology startup Orchid on Tuesday announced a comprehensive new genetic test that may help many prospective parents across the U.S. breathe a little easier. Orchid said its new test will help couples identify whether their embryos present genetic risks such as birth defects, neurodevelopmental disorders, chromosomal abnormalities, or pediatric and adult-onset cancers that were previously only detectable after birth. IVF is a taxing process that can cost an average of more than $12,000 in the U.S., according to the Institute for Reproductive Health. Success is not guaranteed, and some people go through multiple rounds of IVF before a pregnancy develops. Orchid's genetic test will cost couples an additional $2,500 per embryo sequenced, but it does not add any new steps or risks to the IVF process, Siddiqui said.

Persons: Noor Siddiqui, Siddiqui, Couples Organizations: CNBC, Institute for Reproductive Health, Austin Locations: Dublin, Ireland, U.S, Los Angeles, Chicago, Miami

☆ Orchid tests embryos for genetic diseases. It just raised $12 million with this 11-slide pitch deck.
▼ + stars: | 2023-12-05 | by ( Riddhi Kanetkar | ) www.businessinsider.com time to read: +4 min

Orchid, a startup that tests embryos for genetic diseases, has just raised $12 million. "The way that IVF and embryo screening works today is the amount of information available is really limited," Orchid CEO and cofounder Noor Siddiqui said. Genetic testing has been around for years, but it has been usually limited in the diseases it can identify, which include cystic fibrosis, Bloomberg reported. Orchid produces reports with two types of genetic testing: monogenic and polygenic. The cost of the test depends on the number of embryos that Orchid tests.

Persons: Noor Siddiqui, Siddiqui, Orchid, Dylan, Anne Wojcicki, Fidji Simo, Peter Kraft Organizations: Business, Bloomberg, Prometheus Fund, Starbloom Capital, One Ventures, Los Angeles Times Locations: San Francisco, Pebblebed

☆ Not so dead as a dodo: ‘De-extinction’ plan to reintroduce bird to Mauritius
▼ + stars: | 2023-12-01 | by ( Tom Page | ) edition.cnn.com time to read: +10 min

CNN —An audacious collaboration between geneticists and conservationists plans to bring back the extinct dodo and reintroduce it to its once-native habitat in Mauritius. But according to the partners, its return to Mauritius could benefit the dodo’s immediate environment and other species. The Nicobar pigeon, native to the coastal regions from the Andaman and Nicobar Islands, is the closest living relative to the dodo. Then it will edit the PGCs of a Nicobar so it expresses the physical traits of a dodo. “I have studied the dodo for many years, and there is still a lot to learn about this enigmatic bird,” he added.

Persons: dodo, Beth Shapiro, ”, Matt James, James, Holger Hollemann, Tatayah, ” Tatayah, “, dodos, Ben Birchall, Julian Hume, ” Hume, Ben Lamm, “ We’re Organizations: CNN, Colossal Biosciences, Mauritian Wildlife Foundation, Getty, Gorges, Colossal, “, White Rhino, Biosciences Locations: Mauritius, Rodrigues Island, Asia, Nicobar, Park, “ Mauritius, Aigrettes, Ile

☆ A leading supplement researcher says she doesn't take any — because she's getting what she needs from her vegan diet
▼ + stars: | 2023-11-28 | by ( Hilary Brueck | ) www.businessinsider.com time to read: +6 min

A leading supplement researcher says she doesn't take supplements. She prioritizes getting the key vitamins and nutrients she needs from vegan food. She keeps close tabs on her own health, and the regular tests and checks she performs on herself suggest she doesn't need supplements. Maier prefers getting her vitamins from whole foods"My supplement strategy? All of this goes into Maier's clinical decision-making about whether to try a certain supplement on a specific patient.

Persons: prioritizes, —, Andrea Maier, Maier isn't, She's, Maier, Galina Zhigalova, It's Organizations: Service, Centre, Healthy Longevity, National University of Singapore, Longevity Locations: Singapore

☆ A mysterious respiratory illness that infects dogs is spreading across the US. Here's how to protect your pooch, and what to do if you think they have it.
▼ + stars: | 2023-11-21 | by ( Maiya Focht | ) www.businessinsider.com time to read: +5 min

AdvertisementA mysterious respiratory illness is spreading between dogs across the US, and veterinarians aren't sure what's causing it. AdvertisementHere's what to look out for in your pooch, and how to do your best to protect your dog against infection. How to protect your pupIt's best to avoid areas with high dog traffic while this sickness is spreading. Advertisement"I think we've all learned more than we ever wanted to know about respiratory disease and how it passes over the last few years. What to do if you think your dog got infectedMcKnight recommends taking your dog to the vet to get a workup done if you think they may have symptoms.

Persons: —, aren't, Sorin McKnight, McKnight, hasn't, Dr, Silene St, Bernard, Andrea Cantu, MIGUEL MEDINA, St.Bernard, Supitnan Pimpisarn, St Organizations: Service, Veterinary Medical Center, University of New, Laboratory, Hubbard Center for Genome Studies, NBC, Oregon Department of Agriculture, American Veterinary Medical Association, Getty, Associated Press, St Locations: Texas, Silene, Oregon, Colorado , New Hampshire, Massachusetts, AFP

Veterinary laboratories in several states are investigating an unusual respiratory illness in dogs, and encouraging people to take basic precautions to keep their pets healthy as veterinarians try to pin down what's making the animals sick. Oregon, Colorado and New Hampshire are among the states that have seen cases of the illness, which has caused lasting respiratory disease and pneumonia and does not respond to antibiotics. Symptoms of respiratory illness in dogs include coughing, sneezing, nasal or eye discharge and lethargy. Some cases of the pneunomia progress quickly, making dogs very sick within 24 to 36 hours. Dogs have died, said Kurt Williams, director of the Oregon Veterinary Diagnostic Laboratory at Oregon State University.

Persons: Kurt Williams, Williams, David Needle, Robert Wood Johnson Organizations: Oregon Department of Agriculture, U.S . Department of, National Veterinary Services Laboratory, Oregon Veterinary Diagnostic, Oregon State University, University of New, Diagnostic, Hubbard, for Genome Research, Associated Press Health, Science Department, Robert Wood Johnson Foundation, AP Locations: Oregon , Colorado, New Hampshire, Oregon, University of New Hampshire's New Hampshire, Rhode Island , New Hampshire, Massachusetts

☆ Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval
▼ + stars: | 2023-11-16 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com time to read: +1 min

Regulators in Britain on Thursday approved the first treatment derived from CRISPR, the revolutionary gene-editing method. Called Casgevy, the treatment is intended to cure sickle-cell disease and a related condition, beta thalassemia. The companies anticipate that the Food and Drug Administration will approve Casgevy for sickle-cell patients in the United States in early December. The agency will decide on approval for beta thalassemia next year. That treatment does not rely on gene editing, insteading using a method that inserts new DNA into the genome.

Organizations: Vertex Pharmaceuticals, CRISPR Therapeutics, and Drug, Bluebird Bio Locations: Britain, Boston, Switzerland, United States, Somerville, Mass

☆ Ruzwana Bashir Is Quietly Connecting the Tech World
▼ + stars: | 2023-11-16 | by ( ) www.businessinsider.com time to read: +18 min

Story by Melia RussellPhotography by Lelanie FosterRuzwana Bashir is ransacking her kitchen cabinet for just the right tea. Bashir wears an Erdem floral-printed bra top, Erdem skirt, Giuseppe Zanotti shoes, Old Jewelry earrings along with her own bracelet and ring. "Part of building a business was going out and sharing what you were doing with the world," Bashir says. For years Bashir's startup had been building muscle around these capabilities; now it had an eager audience. Eating at acclaimed restaurants is fine, but Bashir prefers the more-intimate affairs at tech executives' homes because, she says, "you can stay longer."

Persons: Melia Russell, Lelanie Foster Ruzwana Bashir, Peek, She's, she's, Andy Warhol, Picasso, Bashir, I'm, Andreessen Horowitz, Jack Dorsey, Eric Schmidt, Goldman Sachs, Giuseppe Zanotti, Lelanie Foster, Bashir isn't, Elon Musk, Ronan Farrow, Roelof Botha, Mustafa Suleyman, we've, Bennett Miller, Capote, " Miller, —, doesn't, didn't, Madeleine Albright, Tom Ford, Jared Cohen, Oskar Bruening, Forbes, Mark Zuckerberg, I've, Bashir wasn't, Travis Kalanick, Adam Neumann, Ty, Emily Weiss, Bashir refashioned, Donald Trump, Bruening, Laurence Tosi's, Miller, Beyoncé, shrugs, Anna Wintour, Anna, we're, Taylor Swift, Katie Haun, Marc Benioff, Reid Hoffman, Marissa Mayer, Dick Costolo —, Cohen, Katherine Maher, Maher, Daniel Kahneman, It's, Radel, Becky Akinyode, Elaine Winter, Tiffany Bloomfield, Dela, Chad Hilliard, Enmi, Kenny Aquiles Ulloa, Cyrenae, Madison Perez, Aidan Lapp, Bashira Webb, Bryan Erickson, Jinyoung Chang, Rodriguez, Rebecca Zisser, Claire Landsbaum, Emma LeGault, Joi, Marie McKenzie, Conner Blake, Kyle Desiderio, Victoria Gracie, Nicole Forero, Virginia Alves Organizations: Google, Museum of, Business, Elon, Vogue, Roelof, Oxford University, Oxford Union, Blackstone Group, Harvard Business School, Studios, Web, Young, Organization, Dela Revoluciøn, Enmi Yang Digital Tech Locations: Manhattan, SoHo, Bahamas, United States, Balthazar, England, Israel, Petra, Istanbul, Elle, Utah, COVID, Salt Lake City, Costa Rica, Atlanta, WestCap

☆ How head lice reveal secrets about human origins
▼ + stars: | 2023-11-13 | by ( Manav Tanneeru | Katie Hunt | ) edition.cnn.com time to read: +5 min

CNN —Head lice have been constant, if unwanted, human companions for as long as our species has been around. Some 20 years ago, David Reed, a coauthor of the new study and a researcher and curator at the Florida Museum of Natural History, found that human head lice are composed of two ancient lineages, with origins predating Homo sapiens. Doing so allowed researchers to detect the hybrid lice and better capture the genetic diversity of head lice. Ascunce said she had hoped the information they gleaned might answer whether Neanderthal head lice are still around today, but the 15 genetic markers, known as “microsatellites,” that they studied in the lice nuclear DNA didn’t reveal that information. “New ongoing studies are being done using whole genome sequences from human lice, so stay tuned for more exciting research on that.”

Persons: ”, Marina Ascunce, Jeff Gage, Ascunce, It’s, David Reed, sapiens, “ Organizations: CNN, US Department of Agriculture, Plos, Florida Museum, University of Florida Locations: Brazil, Africa, Americas

☆ Parasitic worms highjack their hosts' free will, and scientists finally think they know how
▼ + stars: | 2023-11-11 | by ( Emily Hein | ) www.businessinsider.com time to read: +6 min

Horsehair worms can control a host's brain and steer it to water, where it drowns. These parasitic worms, which resemble dark and stringy horse hair, take control of their host's brain and drive it to suicide. Hairworms' magic copy-cat trickHairworms need water to reproduce, so when they're ready they force their host to water, where ultimately the host drowns. Horsehair worms make their hosts more active in the middle of the day , when it's easier to find light reflecting off water. So the Chordodes worms can only control mantises and can't puppeteer other insects or mammals, according to the study.

Persons: what's, —, they're, it's, hairworms, Tappei Mishina, Hairworms, Rather, Mishina Organizations: Service, University of California's, Pest Management

☆ CDC to expand disease surveillance at four major US airports to include flu, RSV
▼ + stars: | 2023-11-06 | by ( Manav Tanneeru | Amanda Musa | ) edition.cnn.com time to read: +5 min

CNN —The US Centers for Disease Control and Prevention is expanding its infectious disease surveillance program at four major US airports to more than 30 pathogens, including flu, RSV and other respiratory viruses. The program currently operates Covid-19 surveillance at seven major international airports in the United States. The traveler surveillance program was introduced in 2021 when the CDC began collecting nasal swab samples from anonymous international travelers arriving at participating airports who volunteer to get swabbed. The program has collected samples from travelers from more than 135 countries and has sequenced more than 14,000 samples for further analysis. The wastewater program, which was introduced in August 2022, collects wastewater from a single plane using a custom-made collection device.

Persons: Dr, Cindy Friedman, John F, “, ” Friedman, Friedman, Ginkgo Bioworks, Matthew McKnight, ” McKnight, Sanjay Gupta, Deidre McPhillips Organizations: CNN, Centers for Disease Control, CDC’s, Health, Boston Logan International Airport, San Francisco International Airport, Dulles International, Washington , D.C, Kennedy International, CDC, Get CNN, CNN Health Locations: United States, Washington ,, New York, Ginkgo

☆ AI holds promise for fast-tracking treatment and personalizing medicine — but it may not come to your clinic anytime soon
▼ + stars: | 2023-10-20 | by ( Heather Lindsey | ) www.businessinsider.com time to read: +6 min

Tsai predicts that AI will one day help doctors analyze complicated genetic data — a hallmark of precision medicine. Together, AI imaging and genetic analysis may help doctors rapidly pinpoint a diagnosis and create a highly personalized treatment plan, thus improving a patient's care. AI and the potential for genetic analysisIn addition to medical imaging, AI could one day comb through large amounts of genetic information, a challenging task for researchers. A possible convergence in the clinicWang does not see combining AI imaging and AI genetic analysis at the doctor's office happening within the next couple of years. Chang and his colleagues are investigating how AI analysis of brain scans can predict genetic mutations in brain tumors.

Persons: James C, Tsai, Peter D, Chang, Zhenghe J, Wang Organizations: Healthcare, Morning, Center, Ophthalmic Artificial Intelligence, Human, Icahn School of Medicine, US Food and Drug Administration, Applied, Research, University of California, Case Western Reserve University Locations: Mount, Irvine

Scientists are setting out to collect genetic material from 500,000 people of African ancestry to create what they believe will be the world’s largest database of genomic information from the population. The initiative was launched Wednesday by Meharry Medical College in Nashville, Tennessee, as well as Regeneron Genetics Center, AstraZeneca, Novo Nordisk and Roche. Organizers said there’s a clear need for the project, pointing to research showing that less than 2% of genetic information being studied today comes from people of African ancestry. Each of the pharmaceutical companies involved intends to contribute $20 million toward the genetic and educational parts of the effort. ___The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group.

Persons: Meharry, ”, Anil Shanker, Lyndon Mitnaul Organizations: Meharry Medical College, Genetics Center, AstraZeneca, Novo Nordisk, Roche, Genomics Institute, Organizers, Regeneron Genetics, University of Zambia, Project, Genetics, Corporate, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: Nashville , Tennessee, Americas, Asia, Europe, Nashville, U.S, Africa, Meharry

☆ Scientists may have untangled a mystery of Neanderthal ancestry
▼ + stars: | 2023-10-18 | by ( Katie Hunt | ) edition.cnn.com time to read: +4 min

CNN —A new analysis of ancient genomes is deepening scientists’ understanding of the Neanderthal DNA carried by human populations in Europe and Asia — genetic traces that may have medical relevance today. The researchers found that, over time, the distribution of Neanderthal DNA didn’t always look as it does now. This resulted in a lower proportion of Neanderthal DNA observed in European genomes during this period. “The thing was that they had less Neanderthal ancestry so they diluted the (Neanderthal ancestry) in European populations,” Currat said. For example, Neanderthal DNA may play a small role in swaying the course of Covid-19 infection, according to a September 2020 study.

Persons: we’ve, ”, Mathias Currat, Currat, Dr, David Reich, ” Currat, Tony Capra, wasn’t Organizations: CNN, University of Geneva, Harvard Medical School, Bakar Computational Health Sciences Institute, University of California Locations: Europe, Asia, Altai, Central Asia, Eurasia, East Asia, Boston, Anatolia, what’s, Turkey, Western, Northern Europe, Bakar, San Francisco

☆ Medical imaging struggles to read dark skin. Researchers say they’ve found a way to make it easier
▼ + stars: | 2023-10-16 | by ( Kaitlyn Schwanemann | ) edition.cnn.com time to read: +5 min

CNN —Traditional medical imaging – used to diagnose, monitor or treat certain medical conditions – has long struggled to get clear pictures of patients with dark skin, according to experts. Researchers say they have found a way to improve medical imaging, a process through which physicians can observe the inside of the body, regardless of skin tone. They found that a distortion of the photoacoustic signal that makes the imaging more difficult to read, called clutter, increased with darkness of skin. The applications of photoacoustic technology vary, but with the researchers’ new developments, it may help diagnose health issues more accurately and equitably. We know there’s no basis in the human genome for racial sub-speciation.”This study isn’t the first to find skin color biases in medical technology.

Persons: –, Muyinatu Bell, it’s, ” Bell, Theo Pavan, “, ” Pavan, ”, Guilherme Fernandes, Camara Jones, ” Jones, Bell Organizations: CNN, Ultrasonics Systems, JHU, University of São Paulo, American Public Health Association Locations: Brazil

☆ Last victim of 'Happy Face Killer' is identified, investigators say
▼ + stars: | 2023-10-07 | by ( Faith Karimi | ) edition.cnn.com time to read: +4 min

Florida authorities this week identified her as Suzanne Kjellenberg, who was 34 when she was killed in Jesperson’s cross-country murder rampage. Landscapers found her remains along Interstate 10 in September 1994, said Sheriff Eric Aden of Okaloosa County in Florida. Jesperson, dubbed the “Happy Face Killer” for his letters, had confessed to killing a woman named “Susan” or “Suzette” after his arrest at the time, but her identity was unknown for decades, Aden said. Serial killer detailed victim’s last momentsJesperson got the nickname “Happy Face Killer” after he sent confessions to journalists and police departments around the country to gain notoriety. A break in the case came when the medical examiner’s office sent samples to Othram, a Texas-based company specializing in forensic genetic genealogy.

Persons: CNN —, Keith Hunter Jesperson, Suzanne Kjellenberg, Landscapers, Eric Aden, ”, Susan ”, Suzette ”, Aden, Jesperson, Kjellenberg, Troy Wayrynen, ” Aden, “ Suzanne Organizations: CNN, Sheriff’s, Oregon State, ”, FBI Locations: United States, Florida, Okaloosa County, Okaloosa, California , Nebraska , Wyoming , Oregon, Washington, Oregon, Aden, Tampa, Holt, Texas, Wisconsin

BRUSSELS, Oct 2 (Reuters) - The European Commission will assess the risks of four critical technologies, including semiconductors and artificial intelligence, being weaponised by countries not aligned with its values and will take measures next year to tackle the issue, an EU official said on Monday. The other two critical technologies on the EU list are quantum technologies and biotechnologies such as vaccines and genome sequencing. "The Commission will do risk assessments of these four technologies with member states. The next step is to mitigate the risks next year," the official told Reuters on condition of anonymity. Commission Vice President Vera Jourova and EU industry chief Thierry Breton will hold a press conference on the issue at 1330 GMT on Tuesday.

Persons: Vera Jourova, Thierry Breton, Foo Yun Chee, Richard Chang Organizations: European, EU, Reuters, Thomson Locations: BRUSSELS, United States, Australia, China, Ukraine

And I told her that many, many scientists work very, very hard," Kariko added. BioNTech said in June that about 1.5 billion people across the world had received its mRNA shot, co-developed with Pfizer (PFE.N). [1/11]Katalin Kariko and Drew Weissman win the 2023 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm, Sweden October 2, 2023. The medicine prize kicks off this year's Nobel awards with the remaining five to be unveiled in coming days. The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel.

Persons: Weissman, Katalin Kariko, Drew Weissman, Kariko, BioNTech, Rickard Sandberg, Susan Francia, immunologist, ”, Sir Andrew Pollard, Alfred Nobel, Swede Svante Paabo, Alexander Fleming, Karl Landsteiner, Niklas Pollard, Johan Ahlander, Ludwig Burger, Terje Solsvik, Andrew Cawthorne Organizations: Medicine, Nobel, Sweden's Karolinska Institute, University of Szeged, University of Pennsylvania, Pfizer, Karolinska Institute, TT News Agency, REUTERS Acquire, Boston University, Oxford University, AstraZeneca, Moderna, Thomson Locations: STOCKHOLM, COVID, Hungary, Pennsylvania, Szeged, U.S, Stockholm, Sweden, Frankfurt, Krisztina, Budapest, Oslo

☆ What the Nobel Prizes get wrong about science
▼ + stars: | 2023-09-29 | by ( Katie Hunt | ) edition.cnn.com time to read: +9 min

Peter Brzezinski, the secretary of the committee for the Nobel chemistry prize, said there were no plans to change the rule. He said the Nobel Prize committees, at least for science prizes, are “innately conservative.”DiversityOther criticism leveled at the Nobel Prizes includes the lack of diversity among winners. Of course, these flaws and gaps only matter because the Nobels are far better known than other science prizes, Rees added. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature and the Nobel Peace Prize will be announced on Thursday and Friday, respectively.

Persons: Alfred Nobel, Martin Rees, Rees, ”, Jonathan Nackstrand, Rainer Weiss, Barry Barish, Kip Thorne, David Pendlebury, “ Nobel, ” Pendlebury, Nobel’s, Peter Brzezinski, “, ” Brzezinski, John Jumper, AlphaFold, Lasker, Pendlebury, Emmanuelle Charpentier, Jennifer Doudna, it’s, Carolyn Bertozzi, Andrea Ghez, Naomi Oreskes, Henry Charles Lea, ” Rees Organizations: CNN, Royal Society, Getty, Clarivate’s Institute for Scientific, Nobel Foundation, Academy, Google, Harvard University Locations: Swedish, AFP, Stockholm

☆ Stocks making the biggest moves before the bell: Nike, Blue Apron, Bumble and more
▼ + stars: | 2023-09-29 | by ( Alex Harring | ) www.cnbc.com time to read: +2 min

Check out the companies making headlines in premarket trading. Nike — The sneaker behemoth added nearly 10% in premarket trading after a mixed earnings report. Brinker International — The Chili's parent climbed 4% after Stifel upgraded the stock to buy from hold. Editas Medicine — The genome editing company popped 9% in premarket trading following a Stifel upgrade to buy from hold. Ball — Shares added 1.7% in premarket trading after the aluminum-can maker was upgraded by Jeffries to buy from hold.

Persons: Brinker, Stifel, Jeffries, —, Northcoast, CNBC's Brian Evans, Pia Singh, Jesse Pound, Michelle Fox Organizations: Nike, Opry, LSEG, Uranium Energy, Wonder Group, Anheuser, Busch InBev —, Bank of America, Stifel, KFC, Research Locations: Nashville , Tennessee, Olive

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