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☆ Insiders say Oracle is crushing morale at $28 billion acquisition Cerner by cutting over 3,000 workers, banning raises, and sidelining its former CEO
▼ + stars: | 2023-05-16 | by ( Ashley Stewart | Blake Dodge | ) www.businessinsider.com time to read: +3 min

After the acquisition closed in June, Oracle has laid off more than 3,000 of the 28,000 original Cerner employees, one of the people said. According to his LinkedIn, Feinberg left the CEO role in September before becoming "chairman" of Oracle Health. After Johnson left, Oracle moved data and artificial-intelligence back under its cloud business. Internally, the face of the unit appears to be Oracle Health General Manager Travis Dalton, who has been in charge of all-hands meetings. Oracle Health is in charge of a contract worth several billion dollars to overhaul the US Department of Veterans Affairs' information systems.

☆ Sleep apnea, lack of deep sleep linked to damage in brain, study says
▼ + stars: | 2023-05-10 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

If the sleep apnea is severe and untreated, people have three times the risk of dying from any cause. People with severe sleep apnea who spent less time in deep, also known as slow-wave sleep, had more damage to the white matter of the brain than people who had more slow-wave sleep, according to the study. “The association with sleep apnea was only unveiled when we isolated severe cases, suggesting that mild to moderate sleep apnea may not be significantly associated with white matter changes,” he said. About 34% of the participants had mild sleep apnea, 32% had moderate and 34% had severe sleep apnea. People with sleep apnea, however, can have dozens of micro-awakenings during the night as they snore, snort or gasp for breath.

☆ Is your job ruining your sleep? If so, this may be why
▼ + stars: | 2023-05-09 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

Experiencing negative changes in workplace leadership and fairness was associated with the strongest long-term impact on a worker's sleep. LumiNola/E+/Getty ImagesSleep problems included initiating or maintaining sleep, poor-quality sleep and daytime tiredness two to four times a week that lasted one month to three months. Within a two-year period of time, over half of the participants (53%) reported changes in their workplace environment. However, if the changes at work were negative, sleep issues increased — in fact 1 in 4 people in the study with a worse job environment developed problems getting enough rest. Having negative changes in the leadership and fairness sector was associated with the greatest long-term impact on sleep, more than negative changes in coworker relationships or collaboration, the study found.

☆ Study finds 45 negative health effects of added sugar
▼ + stars: | 2023-04-05 | by ( Kristen Rogers | ) edition.cnn.com time to read: +7 min

CNN —There are at least 45 good reasons to cut back on added sugar, according to a new study. Copious research has shown the negative effects of excessive sugar intake on health, which has informed recommendations to limit consumption of “free” or added sugar to less than 10% of a person’s daily caloric intake. “This means that whole, intact grains don’t cause the same spikes in blood sugar that we experience when we eat simple sugars. A doughnut has around 15 to 30 grams of sugar, according to the Cleveland Clinic. Cooking and baking at home more often is one of the best ways to reduce sugar intake, Aggarwal said.

☆ This LA mansion is staring down an April 1 deadline before the seller loses millions
▼ + stars: | 2023-03-24 | by ( Ray Parisi | ) www.cnbc.com time to read: +8 min

EstateLuxShootTrying to unload an expensive mansion in the midst of a banking crisis with the LA real estate market softening and uncertainty looming large isn't exactly great timing. Feinberg, like all luxury mansion sellers in LA, is also contending with the new mansion tax approved by voters in November. Yann IppolitoFor homes priced between $5 million and $10 million, sellers will have to pay the city 4% of the total sale price. According to his calculations, all of those sellers combined would have racked up a mansion tax bill of almost $131 million. "When New York implemented the mansion tax in 2019, there was a surge in closings just short of the July 1 start date and a void of sales in the following months," he said.

☆ Clinics are trying to sell trendy weight-loss injections by flooding TikTok with videos about semaglutide
▼ + stars: | 2023-03-02 | by ( Sindhu Sundar | Alex Bitter | ) www.businessinsider.com time to read: +9 min

The video, which has nearly 60,000 likes, is among a proliferation of TikTok posts tagged with the names of semaglutide weight-loss drugs, including Wegovy and Ozempic. "What drives the video to go viral is if you can generate some kind of discussion," he told Insider. Unlike official ads, partnerships, or promotions, TikTok posts receive little oversight from government agencies or medical boards. All four said the TikTok posts are driving an influx of patients to their clinics. Oden told Insider that her videos are "drumming up quite a bit of new business" among patients of all ages.

☆ Biden, 80, to have closely watched physical exam
▼ + stars: | 2023-02-16 | by ( Steve Holland | ) www.reuters.com time to read: +2 min

[1/2] U.S. President Joe Biden delivers remarks on the economy at the IBEW Local 26 in Lanham, Maryland, U.S., February 15, 2023. REUTERS/Evelyn HocksteinWASHINGTON, Feb 16 (Reuters) - President Joe Biden, 80, will undergo a closely watched physical examination on Thursday, ahead of an expected announcement that he is seeking a second four-year term. His last physical and colonoscopy, in November 2021, showed the president to be a "healthy, vigorous, 78-year-old male," his doctors said. At his last exam, Biden's White House physician, Kevin O'Connor, declared him fit for duty and able to execute his responsibilities. Biden told Judy Woodruff in a PBS interview last week that any Americans concerned about his age should "watch me" perform the duties of the presidency.

☆ Radioligand therapy, a 'game-changer' for cancer treatment, forces manufacturers to race against a ticking clock
▼ + stars: | 2023-02-11 | by ( Ashley Capoot | ) www.cnbc.com time to read: +12 min

Ash from the eruption disrupted flights across Europe — including a time-sensitive shipment of experimental radioligand therapy that Sartor was expecting from Norway. Radioligand therapy, also called radionuclide or radiopharmaceutical therapy, is a targeted form of cancer treatment that delivers radiation directly to cancer cells. Once the radioactivity decays, it can no longer kill the cancer cells as effectively, which means radioligand therapy has a limited window of viability. Expensive to produce and ship fastNuclear medicine has been used to treat cancer for decades, and radioligand therapy itself is not new. In 2008, he traveled to a medical conference in Toronto where he heard about radioligand therapy for the first time.

☆ Twitch suspended a GPT-powered AI comedy show trained on 'Seinfeld' episodes after it made transphobic comments
▼ + stars: | 2023-02-06 | by ( Travis Clark | ) www.businessinsider.com time to read: +2 min

An AI-powered comedy shoe trained by "Seinfeld" episodes was suspended from Twitch. The stream, called "Nothing, Forever," had made transphobic comments shortly before the suspension. The notice doesn't specify the reason for the suspension, but it came soon after Sunday night's stream included transphobic and anti-LGBTQ+ comments, according to Vice. One of the "Nothing, Forever" creators, called Xander, said on Discord that the suspension is for 14 days, according to Vice. "We've appealed the ban, and we'll let you know as we know more on what Twitch decides," Xander said.

☆ Box office hits 'Everything Everywhere,' 'Elvis' and 'Avatar' land Oscar nominations
▼ + stars: | 2023-01-24 | by ( Lisa Richwine | ) www.reuters.com time to read: +5 min

"Everything Everywhere," a science-fiction flick about an exasperated Chinese immigrant struggling to finish her taxes, landed 11 nominations, including best picture and four acting nods. Other films in the hunt for the top trophy at the Academy Awards included sequel "Avatar: The Way of Water," James Cameron's visual spectacle that currently ranks as the sixth-highest grossing movie of all time. Last year's Academy Awards ceremony, when Will Smith slapped presenter Chris Rock before winning best actor, drew about 15.4 million TV viewers, the second-smallest audience ever. Apple TV+ (AAPL.O) nabbed best picture last year for heartwarming drama "CODA." This time, Disney received the most nominations, a total of 22, for movies including "Avatar," "Banshees" and animated "Turning Red."

☆ U.S. FDA approves Eisai, Biogen Alzheimer's drug
▼ + stars: | 2023-01-06 | by ( Deena Beasley | ) www.reuters.com time to read: +2 min

[1/2] The logo of Eisai Co Ltd is displayed at the company headquarters in Tokyo, Japan, March 8, 2018. REUTERS/Issei KatoJan 6 (Reuters) - The U.S. Food and Drug Administration on Friday approved the Alzheimer's drug lecanemab developed by Eisai Co Ltd (4523.T) and Biogen Inc (BIIB.O) for patients in the earliest stages of the mind-wasting disease. Eisai said the drug would launch at an annual price of $26,500. Eisai officials have said the company also plans to submit data from a recent successful clinical trial in 1,800 patients as the basis for a full standard review of Leqembi. That trial found that Leqembi, which is given by infusion, slowed the rate of cognitive decline in patients with early Alzheimer's by 27% compared to a placebo.

☆ Box-office hits like 'Top Gun' and 'Avatar' could make waves at the next Oscars as the show fights for viewership
▼ + stars: | 2022-12-21 | by ( Travis Clark | ) www.businessinsider.com time to read: +5 min

"Top Gun: Maverick," "Avatar: The Way of Water," and more box-office hits are in Oscar contention. Now, with the Oscars fighting for viewership, box-office hits like "Top Gun: Maverick" — this year's biggest movie so far — and "Avatar: The Way of Water" — which is chasing that title — may be in contention for the top prize at the 2023 ceremony. The declining viewership has, in recent years, prompted the organization behind the Oscars, the Academy of Motion Picture Arts and Sciences, to try to inject the show with changes. The aforementioned "Top Gun: Maverick" is a formidable player in this year's awards race, as is "Avatar: The Way of Water." The movie, which was made for $25 million, grossed $103 million worldwide, making it indie studio A24's biggest film ever.

☆ A new wave of companies is making testosterone easily available online. The authors of a recent study say there could be risks to patients.
▼ + stars: | 2022-12-09 | by ( Sarah Braner | ) www.businessinsider.com time to read: +6 min

A recent study reviewed seven companies that prescribe testosterone therapy online. These companies say that they make treatment more accessible for people who already suspect they have low testosterone. A new study shows that DTC companies do not all follow medical guidelinesThe new study encourages patients looking to get testosterone therapy online to educate themselves before taking the leap. The study found that six out of seven of the companies tested offered testosterone therapy to the shopper. The study was not meant to evaluate companies prescribing testosterone for gender affirming hormone therapy, which is a different process than testosterone replacement therapy.

☆ Netflix's 'Wednesday' is competing with the streamer's biggest hits, 'Stranger Things' and 'Squid Game,' for record-high viewership
▼ + stars: | 2022-12-07 | by ( Travis Clark | ) www.businessinsider.com time to read: +3 min

Netflix's "Wednesday" is already one of the streamer's biggest TV originals ever after two weeks. Its viewership is on pace to pass "Stranger Things" season four and is rivaling its top show, "Squid Game." "Wednesday" also had Netflix's biggest first week of viewership ever, beating "Stranger Things" season four. The show is chasing the Korean-language series "Squid Game" to be Netflix's biggest original show of all time, Netflix co-CEO Ted Sarandos said at an event in New York City on Tuesday. "This group is far more likely to be among highly engaged viewers because the series has strong overlap with other young-skewing Netflix shows," including "Stranger Things," Alexander wrote.

Economic worries have made this holiday season particularly stressful for some. The holiday season can bring out the absolute worst in some kids. Some parents welcome that break from structure, and that’s OK. “Parents get to decide what works and what doesn’t work with their family,” Dr. Naumburg said. “Gratitude and savoring are the opposite.”Dr. Kurtz recommended starting a simple gratitude practice early in the holiday season. As the holidays unfold, make an effort to savor the season, Dr. Kurtz said.

Participants who were offered cash incentives for either pounds lost or for completing certain activities were more likely to lose weight compared with those who were simply offered tools, such as diet books, fitness trackers and access to a weight loss program, the study found. On average, participants in the goal-directed group earned $440.44, as compared to $303.56 in the outcome-based group. “Even if less weight is lost, adopting lifelong physical activity or better eating habits may be more important,” she said. Kushner, who was not involved with the new study, agreed that low-income people face extra challenges when it comes to weight loss. What’s not clear, however, is how the strategy of offering cash for weight loss could be implemented in a real-world setting, outside of academia.

☆ Poor sleep can make you prickly. Here’s what to do
▼ + stars: | 2022-12-01 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

Develop a sleep debt from those worries, and you’ll pay a price in your ability to think, plan and manage your emotions. “Sleep debt, also called a sleep deficit, is the difference between the amount of sleep someone needs and the amount they actually get,” said sleep specialist Dr. Raj Dasgupta, an associate professor of clinical medicine at the University of Southern California’s Keck School of Medicine. Research has found many people have little idea how much poor sleep has affected their mood and coping skills, said Dr. Bhanu Prakash Kolla, a sleep medicine specialist in the Center for Sleep Medicine at the Mayo Clinic in Rochester, Minnesota. Loss of sleep can directly affect your ability to control emotions and manage expectations, said Dr. Bhanu Prakash Kolla of the Mayo Clinic. “Sleep medications are seldom the solution for chronically poor sleep and impaired daytime functioning,” he said.

☆ Drug and alcohol deaths increasing among US adults 65 and older, CDC data shows
▼ + stars: | 2022-11-30 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +8 min

In 2020, more than 5,000 adults 65 and older in the United States died of a drug overdose. Though drug overdose death rates for older adults tend to be lower than for other age groups – and made up just 0.2% of total deaths among adults 65 and older in 2020 – such deaths have been climbing. Between 2000 and 2020, the rates rose from 2.4 to 8.8 deaths per 100,000 people among adults 65 and older. Between 2000 and 2020, drug overdose deaths increased more among men than women, rising from 2.7 to 12.3 deaths per 100,000 men compared with 2.3 to 5.8 per 100,000 women. “Because of ageism, we typically do not think of older adults as having a substance use disorder nor do we think of older adults for being at-risk for a drug overdose.

☆ Early research suggests promising use of AI to predict risk of heart attack or stroke using a single chest X-ray
▼ + stars: | 2022-11-29 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +5 min

CNN —Early research suggests a promising use of artificial intelligence to predict the 10-year risk of death from a heart attack or stroke from a single chest X-ray. The AI model uses the same risk thresholds as the established risk calculator, and early findings suggest that it works just as well. Sometimes, the AI findings align with a traditional radiology reading, but other times, it picks up on things that may have been missed, he said. He was not involved in the new AI research but says it’s important to keep the field moving forward. “The risk calculator is one part of risk assessment, but it’s not the only part.

☆ Secrets of ‘SuperAgers’ with superior memories into their 80s
▼ + stars: | 2022-11-26 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +7 min

Siegler is a cognitive “SuperAger,” possessing a brain as sharp as people 20 to 30 years younger. She is part of an elite group enrolled in the Northwestern SuperAging Research Program, which has been studying the elderly with superior memories for 14 years. Once accepted, colorful 3D scans are taken of the brain and cognitive testing and brain scans are repeated every year or so. A SuperAger’s brain, usually donated to the research program by participants after death, also has bigger, healthier cells in the entorhinal cortex. SuperAger brains had three times fewer tau tangles, or abnormal formations of protein within nerve cells, than the brains of cognitively healthy controls, the study also found.

☆ Turkey isn’t the reason you’re sleepy – really
▼ + stars: | 2022-11-24 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +3 min

The US Department of Agriculture recommends planning for one pound of turkey meat per person when preparing a holiday meal. “Tryptophan from turkey is unlikely to enter the brain and make enough serotonin to make us sleepy,” Malin said. “Turkey doesn’t really make us sleepy,” Knutson said. “Remember all the delicious side dishes surrounding the center piece of turkey, such as sweet potato pie, casseroles and yummy desserts,” he said. “Alcohol slows down your brain and relaxes your muscles so after a few drinks you’ll likely feel sleepy.”

☆ Does turkey make you sleepy? Here's what causes your food coma
▼ + stars: | 2022-11-24 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +3 min

Why we feel sleepy after a big Thanksgiving mealSerotonin is one of the “feel-good” hormones, which can calm and relax the body. The US Department of Agriculture recommends planning for 1 pound of turkey meat per person when preparing a holiday meal. “Tryptophan from turkey is unlikely to enter the brain and make enough serotonin to make us sleepy,” Malin said. “These tasty dishes contain a high amount of carbohydrates, which also contribute to post-meal sleepiness.”Another reason you feel sleepy after a meal is a change in blood flow from the head to the digestive system. “Alcohol slows down your brain and relaxes your muscles, so after a few drinks you’ll likely feel sleepy.”

Persons: ”, Raj Dasgupta, Steven Malin, ” Malin, Kristen Knutson, ” Knutson, ” Overeating, Dasgupta, ” Dasgupta Organizations: CNN, University of Southern California’s Keck School of Medicine, National Library of Medicine, Rutgers University, Adobe Stock, US Department of Agriculture, Northwestern University’s Feinberg School of Medicine Locations: New Jersey, Turkey

☆ How to save your sleep from the holidays
▼ + stars: | 2022-11-23 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +7 min

“You will enjoy the holidays more if you can protect your sleep time — and you may actually get more done if you aren’t tired and inefficient from sleep deprivation, she said. Watch your alcohol intakeWhile many of us believe that alcohol helps us fall asleep, it actually impairs sleep quality, Dasgupta said. “Remember, alcohol can make you fall asleep faster and sleep heavier during the first portion of the night. “Exercising improves sleep by reducing sleep onset, meaning it takes less time to fall asleep and decreases the amount of time you are lying in bed awake during the night,” Dasgupta said. “Studies have shown that exercise enables individuals with insomnia to fall asleep faster, sleep longer, and enjoy better sleep quality,” he said.

The GVA includes any type of shooting in its analysis including domestic violence, shootings in private homes, gang violence among others. The GVA recorded 610 multiple victim shootings in 2020 and 690 last year, when the pandemic was already easing and the pace of deadly violence increased across the United States. It has been keeping a tally of mass shootings since 2014, when it recorded 273. The GVA counts injuries and deaths in each incident. “Scary to think that in 2016 we recorded 382 mass shootings and now we will probably end 2022 with an estimated 680 mass shootings,” said Herrmann, who based his estimate on the fact that there has been an average of 13 mass shootings a week this year.

☆ Children’s health leaders call for emergency response as respiratory viruses continue to spread across the US
▼ + stars: | 2022-11-18 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +7 min

And health care systems nationwide continue to feel the strain of a respiratory virus season that has hit earlier and harder than usual. There have been about 8 flu hospitalizations for every 100,000 people this season – rates typically seen in December or January. While the Covid-19 emergency declaration remains in place, the federal government has not made a formal emergency declaration around children’s health care. HHS and the CDC are in regular contact with health care leaders and providers, actively monitoring situational needs and ready to provide assistance on a case-by-case basis, an HHS spokesperson told CNN. They also urge all those eligible to get their flu and Covid-19 vaccines, along with other routine vaccinations.

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