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5 Dishes Everyone Should Know How to Grill
  + stars: | 2023-06-02 | by ( Steven Raichlen | ) www.nytimes.com   time to read: +1 min
Grilling may be the world’s oldest, most universal cooking method, but that doesn’t guarantee automatic success. Just ask the person who routinely burns the burgers or whose fish always sticks to the grate. There are five methods of live fire cooking: direct grilling, indirect, smoking, spit-roasting and on the embers, but direct grilling is the most universal. This means cooking tender, small or thin foods, like steaks or chops, directly over a hot fire. Don’t confuse it with barbecue, which uses low, slow heat away from the food to smoke things like Texas brisket and Carolina pork shoulder.
Locations: Texas, Carolina
CNN —A drug used in people in the early stage of the most common kind of breast cancer – HR+/HER2- breast cancer – significantly reduced the risk of the cancer returning after treatment, according to a new study. HR+/HER2- breast cancer has tested positive for progesterone and estrogen receptors and negative for HER2. Endocrine therapy generally works well, but for patients with HR+ or HER- breast cancer, there’s still a 10% to 40% chance that the cancer will come back, some studies show. The new trial found that when Kisqali is added to endocrine therapy, it reduces the risk of recurrence by 25% across a broad population of patients with early breast cancer. About 90% of patients who have breast cancer are diagnosed in the early stages.
Persons: there’s, Kisqali, , Dennis J, Slamon, Sara Tolaney, ” Tolaney, Anupama Goel, Goel, Dr, Sanjay Gupta, Alberto Montero, ” Montero, Montero Organizations: CNN, US Food and Drug Administration, American Society of Clinical Oncology, Novartis, UCLA, Comprehensive Cancer Center, Oncology, Dana, Farber Cancer Institute, Mount Sinai Tisch Cancer Center, CNN Health, UH Seidman Cancer Center, Case Western Reserve University School of Medicine Locations: Chicago, Ohio,
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailNovartis CEO Vas Narasimhan on the latest research on a breast cancer drugNovartis CEO Vas Narasimhan joins 'Squawk on the Street' to discuss the latest research that finds Kisqali - a breast cancer drug made by the company - lowers the risk of recurrence by 25%.
Persons: Vas, Vas Narasimhan Organizations: Novartis
She is one of hundreds of Ontario cancer patients who received diluted chemotherapy in the last year and who are still undergoing treatment to beat the disease. The FDA in the past has taken similar action to loosen restrictions on imports when faced with drug shortages. At least 14 cancer drugs are currently in short supply across the U.S. Up to 20% of cancer patients rely on platinum-based chemotherapy drugs such as cisplatin and carboplatin for treatment, according to the National Cancer Institute. Some cancer patients could die if the shortages are not quickly resolved, doctors said.
Persons: Dawn Deslippe, Diane Marley, Richard Lautens, Drug Administration –, Julie Gralow, We're, Gralow, , Abdul Rafeh Naqash, Naqash, Philip Schwieterman, Schwieterman Organizations: Windsor Regional Hospital, Toronto Star, Getty, Drug Administration, CNBC, FDA, U.S, The American Society of Clinical Oncology, World Health, Pharmaceuticals, National Cancer Institute, American Society of Clinical Oncology, Stephenson Cancer Center, University of Oklahoma, University of Kentucky, kiwis Locations: WINDSOR, Ontario, United States, U.S, carboplatin
Ron DeSantis' wife, Casey DeSantis, is a chief confidant key to his political rise. He finished boasting about his "Florida Blueprint," and then his wife, Florida first lady Casey DeSantis, glided onstage. In the geography was Casey DeSantis' autobiography: raised in Troy, Ohio, and college-educated at the University of Charleston. As Florida's first lady, Casey DeSantis' initiatives included childhood emotional resiliency, child welfare, and — as a breast-cancer survivor herself — cancer research. "They did not want woke ideology shoved down the throats of their five years olds while they were in school," Casey DeSantis said.
Florida Governor Ron DeSantis has called his wife Casey DeSantis "my better half and the star of the show." Governor Ron DeSantis, left, and his wife, Casey DeSantis, speak to a crowd at the North Charleston Coliseum in April 2023 in North Charleston, South Carolina. Sean Rayford/Getty ImagesCasey is poised to take a prominent role in her husband's 2024 presidential race, having already joined DeSantis for "fireside chats" in key states. On May 30, she's expected to rally alongside her husband as he holds his first presidential campaign event in Iowa. Together, the couple will be stopping at all 99 counties in Iowa, DeSantis said soon after he launched his 2024 campaign.
Persons: Ron DeSantis, Casey DeSantis, Sean Rayford, Casey, she's, DeSantis, Donald Trump Organizations: North Charleston Coliseum Locations: Florida, North Charleston , South Carolina, Iowa
Jeffrey Epstein was invited to editorial meetings with Scientific American's editor-in-chief. Jeffrey Epstein was invited to editorial meetings with Mariette DiChristina when she was the top editor of Scientific American magazine, according to scheduling emails obtained by Insider. Epstein had the opportunity to attend editorial meetings on September 22 and 29. "10:30-11:30am Mariette DiChristina to hold her Editorial Meeting to discuss story ideas (DO YOU WANT TO ATTEND? She will be at this meeting)," Groff wrote in one such email.
Persons: Jeffrey Epstein, Mariette DiChristina, Epstein, Lesley Groff, Groff, didn't, Stephen Kosslyn, Larry Summers, Denzel Washington, Little Saint James, Eva Andersson, Dubin, JP Morgan Chase, Ghislaine Maxwell, Maxwell, DiChristina Organizations: Morning, Scientific, College of Communication, Boston University, Harvard University, Islands, Dubin, Tisch Cancer Institute, Virgin Islands, New York Times, Massachusetts Institute of Technology Locations: New York, Paris, Little Saint, Midtown Manhattan, Virgin, Manhattan
Opinion | Getting Screened Early for Breast Cancer
  + stars: | 2023-05-29 | by ( ) www.nytimes.com   time to read: +1 min
Overtreatment, No,” by Mehra Golshan (Opinion guest essay, May 18):When I was 44, my routine annual screening mammogram detected a distortion that turned out to be a highly aggressive and dangerous form of breast cancer. Fortunately, because I was screened annually, it was caught at an early stage and was treated with a combination of surgery, chemotherapy and radiation. Now that I’m well into my 60s, I’m grateful every day for the mammogram that caught that deadly cancer early enough to save my life. Statistically, annual mammogram screening for breast cancer before age 50 may not “save enough lives,” but it surely saved mine. Deborah SchuenemanFarmington Hills, Mich.To the Editor:Like Dr. Mehra Golshan, I am a breast cancer surgeon, and I wholeheartedly agree with his view of the new screening guidelines.
Two people in the United States have died with probable cases of fungal meningitis and more than 200 others are at risk after an outbreak of the infection among patients who had surgery in Matamoros, Mexico, the Centers for Disease Control and Prevention said on Friday. The people at risk traveled from the United States to the Mexican clinics for surgical procedures that included liposuction, Brazilian butt lifts and breast augmentation. said that as of Friday two people had died who had been classified as having probable cases of fungal meningitis. There were 11 more probable cases of the infection, based on spinal tap results, and 14 suspected cases, based on symptoms consistent with meningitis, the C.D.C. Health authorities in the United States and Mexico have asked the World Health Organization to issue an emergency declaration in response to the outbreak.
Opinion | Who Should We Honor on Memorial Day?
  + stars: | 2023-05-28 | by ( Kayla M. Williams | ) www.nytimes.com   time to read: +2 min
While I worked in signals intelligence in Iraq, my friend Alyssa Peterson worked in human intelligence. In 2020, more than 6,100 veterans died by suicide. The Vietnam Veterans Memorial, better known as the Wall, is inscribed with over 58,000 names of Americans who died in or supporting combat, or within 120 days of injuries or illnesses incurred in the combat zone. Their names will not be inscribed on the Wall, though the Vietnam Veterans Memorial Fund is seeking to memorialize them in other ways. I will forever mourn and honor her, too, among our war dead this and every Memorial Day, whether or not her name is ever inscribed on a list of those killed in the global war on terrorism.
Developments in cancer research will be in the spotlight as the American Society of Clinical Oncology hosts the world's biggest cancer research conference in Chicago, starting Thursday. The pair has already has won regulatory approval for Enhertu for metastatic HER2-low breast cancer, but the companies are also studying its use in a variety other HER2 tumors in breast cancers. Lilly's drug, Verzenio, is used in high-risk patients with HR-positive HER2-negative breast cancer that is more likely to reoccur and has already breached the patient's lymph nodes. In a research note earlier this month, Guggenheim analyst Seamus Fernandez said Kisqali is already taking market share from Pfizer's Ibrance in metastatic breast cancer. Merck's Keytruda is also being watched for what benefits it could offer early-stage lung cancer patients .
Ron DeSantis' wife, Casey DeSantis, is a chief confidant key to his political rise. He finished boasting about his "Florida Blueprint," and then his wife, Florida first lady Casey DeSantis, glided onstage. In the geography was Casey DeSantis' autobiography: raised in Troy, Ohio, and college-educated at the University of Charleston. As Florida's first lady, Casey DeSantis' initiatives included childhood emotional resiliency, child welfare, and — as a breast-cancer survivor herself — cancer research. "They did not want woke ideology shoved down the throats of their five years olds while they were in school," Casey DeSantis said.
A Texas Whataburger didn't provide reasonable break time for an employee to express breast milk, the DOL said. When the nursing mother left the premises to express milk, the company fired her, the DOL said. Employers have to give staff reasonable break time to express milk for a year after the child's birth. The corporate-owned restaurant in Lubbock, northwest Texas, failed to provide reasonable break time for the employee to express breast milk, the DOL said. And when she did leave the premises to express milk, the company terminated her, the DOL said.
There's an opportunity for investors in pharmaceuticals that's been "underrepresented for a very long time," according to fund manager Philip Ripman of Storebrand Asset Management. The area is women's healthcare, according to Ripman, who manages the $1 billion Storebrand Global Solutions fund. In medical tech funding, only 2% was focused on non-cancer-related women's health conditions. The area of femtech — or software and tech products relating to women's health — is certainly growing. The Storebrand Global Solutions fund invests across four themes : smart cities, circular economy, equal opportunities and renewable energy.
Persons: Philip Ripman, Ripman, Pro, Stocks, Becton Dickinson, Gedeon Richter, annualized Organizations: Storebrand Asset Management, Global Solutions, Mckinsey Locations: femtech, U.S, Europe
People close to Ron DeSantis say he and his wife Casey are like a singular entity: "The DeSanti." They told Politico Casey DeSantis has the most sway over her husband and is "more paranoid than he is." "She is both his biggest asset and his biggest liability," a DeSantis donor told Politico. Ron DeSantis and his wife Casey are so inseparable they've morphed into one collective being that people close to them dub "The DeSanti." She's the scorekeeper, " a high-ranking DeSantis staffer told Politico.
CNN —When Erin Kennedy returns to the boat at the upcoming European Rowing Championships, the occasion will certainly be a joyful one. “It’s something I’ve been sort of dreaming of and kind of manifesting and trying to work towards for the last year. Erin Kennedy is hoping to defend the title she won in Munich alongside Francesca Allen, Giedre Rakauskaite, Edward Fuller and Oliver Stanhope. Kennedy will be back in the boat exactly a year to the day since her diagnosis. So that’s that’s my goal: if I can keep the tears in until after we finished, hopefully on the top of the podium.”
Biomilq, the company behind the breakthrough, had been working for nearly a decade to replicate the process of making human milk — but outside of the body. While the crisis has highlighted the importance of a resilient formula supply, human milk experts, milk bank advocates and Biomilq all stress the same message: Breast milk is best. The startup will likely take a "gradual approach" to introducing its science via "an early-life nutrition product in partnership with one of these bigger companies," Strickland explained. Breast milk is woefully understudied — to the point that it's difficult "to even say what human milk is from a nutritional standpoint," Perrin explained. The company is researching which aspects of human milk its system is best suited to produce.
What I eat instead: When I want something high in protein but low in salt and preservatives, I opt for tofu. What I eat instead: Tofu burgers are surprisingly tasty. What I eat instead: My favorite refreshing, low-calorie beverages are green teas, like an iced matcha or hojicha (which contains less caffeine). What I eat instead: My go-to healthy breakfast alternative is natto, a Japanese dish made from fermented soybeans, with some multigrain rice. What I eat instead: My favorite flavorful spread is kinako, which is made from soy flour and sesame paste.
Here's the latest:ELECTRIC VEHICLE FRICTIONBiden's domestic policy is embodied in working to electrify roadways across the United States. Getting more electric vehicles on the roads is central to his climate change agenda, ensuring the vehicles are "Made in America" is part of his commitment to restore manufacturing jobs. But the IRA's consumer tax credits are tightly linked to the cars' and batteries being made in the U.S., roiling allies in Europe and Asia whose companies sell into U.S. markets. Instead, Japanese and U.S. officials struck a trade deal on electric vehicle battery minerals that expands eligibility for the $7,500 per vehicle EV tax credits in the IRA. NEW RACE FOR SUBSIDIESThe promise of corporate tax credits has renewed interest in investing in the U.S., and Europe has responded with subsidies of their own.
Chick-fil-A’s first-ever restaurant is closing
  + stars: | 2023-05-18 | by ( Jordan Valinsky | ) edition.cnn.com   time to read: +2 min
New York CNN —Chick-fil-A’s first-ever restaurant is closing after more than a half-century in business. Opened in 1967, the Greenbriar Mall food court location in Atlanta is set to close on Saturday, according to local reports. It’s unclear why the restaurant is closing and Chick-fil-A didn’t immediately return CNN’s request for comment. In 1997, a plaque was installed at the mall restaurant to celebrate its 40th anniversary and celebrate how the company pioneered in-mall dining. Its success led him to evolve the restaurant into the Chick-fil-A chain, and some consider that to be the first Chick-fil-A location.
What 40-Somethings Should Know About Breast Cancer
  + stars: | 2023-05-18 | by ( Dani Blum | ) www.nytimes.com   time to read: +2 min
Some biopsies don’t indicate cancer, yet still create anxiety for patients — but many biopsies do find cancer, he said, which saves lives. Many of the factors that contribute to breast cancer risk, like genetics and a family history of cancer, aren’t modifiable; others are within a patient’s control, but not necessarily practical. For example, having a child before age 35 lowers the risk of breast cancer, as does breastfeeding, but a doctor would never recommend a woman have a child by a certain age to reduce cancer risk, said Avonne Connor, a cancer epidemiologist at Johns Hopkins Bloomberg School of Public Health. But a few behaviors have been linked to a lower risk of breast cancer, doctors said. A mounting body of evidence has tied drinking to a higher risk of cancer in general — and potentially to breast cancer in particular, partly because alcohol can boost levels of estrogen in the body.
Democrat Donna Deegan pulled off an upset in Jacksonville, defeating front-running candidate Republican Daniel Davis on Tuesday to become the city's first female mayor. In Philadelphia, former state representative and City Council member Cherelle Parker won the Democratic nomination for mayor. She now faces Republican David Oh in the general election in November, a race she will most likely win in the largely Democratic city. Parker pledged to hire more police officers if she becomes Mayor of Philadelphia, where violent crime remains a chief concern across the nation's sixth largest city. She, like Deegan, would become her city's first female mayor if she wins, taking over for incumbent Democratic mayor Jim Kenney, who was term limited.
DeSantis signed three anti-trans bills into law ahead of an anticipated 2024 run. Though he decried LGBTQ+ material and called for "normalcy" for minors, children stood next to him onstage during the bills' signings. Another bill DeSantis signed into law Wednesday prevents doctors from offering treatments such as hormone therapy, puberty blockers, and surgery — such as breast removal — to transgender minors, even in cases where parents consent. The legislation — officially known as the Parental Rights in Education Act — was panned by LGBTQ+ rights organizations as "Don't Say Gay." But a bill DeSantis signed into law Wednesday went even further to eradicate such teachings so they only happen in the limited curriculum parameters after eighth grade.
Five Germans handed jail sentence for Green Vault jewel heist
  + stars: | 2023-05-16 | by ( ) www.reuters.com   time to read: +2 min
The pieces stolen from the break-in at the Gruenes Gewoelbe (Green Vault) museum in Dresden contained more than 4,300 diamonds with an estimated value of more than 113 million euros. They included a breast star of the Polish Order of the White Eagle and an ornate diamond head-dress. Five members of the same family were handed sentences of between four years and four months and six years and two months. The treasures survived Allied bombing raids in World War Two, only to be carted off as war booty by the Soviet Union. They were returned to Dresden, the historic capital of the state of Saxony, in 1958.
We have also learned over time that not all breast cancer tumors grow or spread at the same rate. For example, a type of breast cancer that I’ve studied, called ductal carcinoma in situ — also known as stage 0 breast cancer — may never progress to invasive disease in a person’s lifetime, and so may require less therapy. Detecting cancer becomes more challenging when trying to distinguish cancer, which also appears white on a mammogram, from dense breast tissue. The task force acknowledged that dense breasts can increase a woman’s risk of breast cancer and that certain race or ethnicity groups are at higher risk for early-onset breast cancer. Black women under 50, for example, die of breast cancer at twice the rate of white women under 50 in the United States.
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