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CNN —This year’s Nobel Prize in physiology or medicine has been awarded to Katalin Karikó and Drew Weissman for their work on mRNA vaccines, a crucial tool in curtailing the spread of Covid-19. The Nobel Prize committee announced the prestigious honor, seen as the pinnacle of scientific achievement, in Sweden on Monday. Rickard Sandberg, a member of the Nobel Prize in medicine committee, said, “mRNA vaccines together with other Covid-19 vaccines have been administered over 13 billion times. They sold their car, Karikó told The Guardian, and stuffed the money – an equivalent of about $1,200 – in their daughter’s teddy bear for safekeeping. Weissman told CNN that their technology is much more efficient than traditional methods of producing vaccines.
Persons: Katalin Karikó, Drew Weissman, , Karikó, Weissman, Rickard Sandberg, ” Karikó, Steffen Trumpf, BioNTech, Penn Medicine J, Larry Jameson, . Weissman, ” Jameson, Drew, , Hope, I’m Organizations: CNN, University of Pennsylvania, Pfizer, Penn Medicine, UPenn’s School of Medicine, Kati, Temple University, Guardian, Moderna Locations: Covid, Sweden, Hungarian, American, Germany, Norway, Hungary, United States, Philadelphia, UPenn
mRNA vaccine: 5 things to know
  + stars: | 2023-10-02 | by ( Katie Hunt | ) edition.cnn.com   time to read: +5 min
Here are five things to know about Karikó and Weissman’s game-changing research and mRNA vaccines. What mRNA doesMessenger RNA, or mRNA, is a form of nucleic acid that tells cells what to do based on the information contained in DNA. Messenger RNA-based vaccine technology doesn’t rely on a modified version of a virus to produce an immune response. Potential beyond fighting Covid-19The advent of mRNA vaccine technology has led to safe and strong protection against Covid-19. And mRNA technology is also being checked out as a possible alternative to gene therapy for intractable conditions such as sickle cell disease.
Persons: Katalin Karikó, Drew Weissman, Peggy Peterson, Robin Shattock, ” Shattock, , Karikó, Weissman, , Roberts, Thomas Perlmann, it’s Organizations: CNN, University of Pennsylvania, Penn Medicine, Imperial College London, Covid, Penn’s Perelman, of Medicine, Vaccine, Perelman School of Medicine, Nobel Assembly Locations: Hungary
And I told her that many, many scientists work very, very hard," Kariko added. BioNTech said in June that about 1.5 billion people across the world had received its mRNA shot, co-developed with Pfizer (PFE.N). [1/11]Katalin Kariko and Drew Weissman win the 2023 Nobel Prize in Physiology or Medicine at the Karolinska Institute in Stockholm, Sweden October 2, 2023. The medicine prize kicks off this year's Nobel awards with the remaining five to be unveiled in coming days. The prizes, first handed out in 1901, were created by Swedish dynamite inventor and wealthy businessman Alfred Nobel.
Persons: Weissman, Katalin Kariko, Drew Weissman, Kariko, BioNTech, Rickard Sandberg, Susan Francia, immunologist, , Sir Andrew Pollard, Alfred Nobel, Swede Svante Paabo, Alexander Fleming, Karl Landsteiner, Niklas Pollard, Johan Ahlander, Ludwig Burger, Terje Solsvik, Andrew Cawthorne Organizations: Medicine, Nobel, Sweden's Karolinska Institute, University of Szeged, University of Pennsylvania, Pfizer, Karolinska Institute, TT News Agency, REUTERS Acquire, Boston University, Oxford University, AstraZeneca, Moderna, Thomson Locations: STOCKHOLM, COVID, Hungary, Pennsylvania, Szeged, U.S, Stockholm, Sweden, Frankfurt, Krisztina, Budapest, Oslo
Covid-induced Nobel Prize is on brand
  + stars: | 2023-10-02 | by ( Robert Cyran | ) www.reuters.com   time to read: +4 min
They realized that modifying lab-made mRNA, a molecule used for protein production, nearly stopped the body from mounting an inflammatory response. It takes, on average, about 25 years between publishing work and receiving the Noble Prize in medicine. There are exceptions: insulin was created in 1921, administered to children in 1922, and the inventors were given the prize in 1923. Contrast that to Ralph Steinman, awarded the prize in Medicine in 2011 for work done in 1973. Follow @rob_cyran on XCONTEXT NEWSKatalin Kariko and Drew Weissman were awarded the Nobel Prize in Medicine on Oct. 2 for their work in a paper published in 2005 in the journal Immunity on mRNA molecule modifications.
Persons: Kariko, Drew Weissman, Ralph Steinman, Germany’s, Weissman, Lauren Silva Laughlin, Aditya Sriwatsav Organizations: Reuters, University of Pennsylvania, Medicine, U.S . Defense Department, Pfizer, Moderna, Thomson Locations: Covid
The Nobel Prize in Medicine was awarded Monday to two scientists whose work led to the mRNA vaccines against COVID-19. As countries prepared to roll out those shots, The Associated Press took a look at how the vaccines were developed so quickly. ___How could scientists race out COVID-19 vaccines so fast without cutting corners? A head start helped -- over a decade of behind-the-scenes research that had new vaccine technology poised for a challenge just as the coronavirus erupted. Both shots — one made by Pfizer and BioNTech, the other by Moderna and the National Institutes of Health — are so-called messenger RNA, or mRNA, vaccines, a brand-new technology.
Persons: Dr, Anthony Fauci, Buddy Creech, ” Creech, Tal Zaks, , Drew Weissman, Weissman, Katalin, Philip Dormitzer, Barney Graham’s, ” Fauci, Graham, Jason McLellan, hadn't, , ” Graham, Germany’s, Pfizer’s Dormitzer, Ugur Sahin Organizations: Medicine, COVID, Associated Press, Vanderbilt University, Infectious Diseases Society of America, Pfizer, BioNTech, Moderna, National Institutes of Health, NIH, University of Pennsylvania, Penn, NIH’s Vaccine Research Center, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Department of Science Education, AP Locations: U.S, Massachusetts, BioNTech, New York, China
Katalin Karikó,(right) PhD, is a biochemist and researcher, best known for her contributions to mRNA technology and the COVID-19 vaccines. Two scientists won the Nobel Prize in medicine on Monday for discoveries that enabled the development of mRNA vaccines against COVID-19. Paabo's father, Sune Bergstrom, won the Nobel Prize in medicine in 1982. The prizes carry a cash award of 11 million Swedish kronor ($1 million). The money comes from a bequest left by the prize's creator, Swedish inventor Alfred Nobel, who died in 1896.
Persons: Drew Weissman, Karikó, Katalin, Thomas Perlmann, Gunilla Karlsson, Svante Paabo, Paabo's, Sune Bergstrom, Alfred Nobel Organizations: COVID, Sagan's University, University of Pennsylvania, Nobel Assembly Locations: Hungary, Swedish, Oslo, Stockholm
Opinion | To Prosecute or Not to Prosecute Trump
  + stars: | 2023-08-18 | by ( ) www.nytimes.com   time to read: +1 min
To the Editor:Re “The Prosecution of Trump May Have Terrible Consequences,” by Jack Goldsmith (Opinion guest essay, Aug. 10), about the charges brought by Jack Smith:Mr. Goldsmith argues that the prosecution of Mr. Trump will further erode the already diminished belief that Republicans have in our justice system and may “inspire tit-for-tat investigations of presidential actions by future Congresses and by administrations of the opposing party.”He may be correct. But the integrity of our democracy is at stake. As the New York University law professors Ryan Goodman and Andrew Weissman have written, “To not have brought this case against Mr. Trump would have been an act of selective nonprosecution” because so many foot soldiers have been prosecuted for their Jan. 6 attempt to disrupt our government. To the Editor:Jack Goldsmith studiously ignores a key factor of this disputed topic. While he details concerns about prosecuting Mr. Trump, he does not touch on the toxic consequences of not prosecuting.
Persons: Jack Goldsmith, Jack Smith, Goldsmith, Trump, Ryan Goodman, Andrew Weissman, , Bruce Kirby Rockville, Jack Goldsmith studiously Organizations: Trump, New York University Locations: Md
Opinion | The Trump Indictment: A Changed Landscape
  + stars: | 2023-06-09 | by ( ) www.nytimes.com   time to read: +1 min
To the Editor:Re “Trump Is Indicted Over Classified Files” (front page, June 9):The indictment of Donald Trump heralds a new chapter in American history. He will continue to tell his followers that he has done nothing wrong and that this is all part of a vendetta by the Washington elite. He could be elected and then have a guilty verdict upheld as he is about to be sworn into office. Mr. Trump and the special counsel Jack Smith serve as the protagonists in the first act of a Shakespearean tragedy. The full effects on America of Mr. Smith’s essential action will not be known until the final act.
Persons: Trump, Donald Trump, Jack Smith, Sidney Weissman Organizations: Republican, Washington, Mr Locations: America
Robert E. Weissman joined Dun & Bradstreet Corp. in 1979 and rose to chief executive there in 1994. Photo: Weissman FamilyFew would have seen Robert E. Weissman as CEO material in 1960. Within four years, Mr. Weissman was a graduate of Babson College. He was embarking on a fast-track career with stops at a maker of liquid detergent, a manufacturer of cable-TV equipment and a provider of computer timesharing services. When he described his experience as “kind of eclectic,” he wasn’t exaggerating.
Trump's former lawyer Michael Cohen has said he made the payment to silence Daniels about an affair she says she had with Trump in 2006. Bragg's charges come at a critical time, as Trump is running for the Republican presidential nomination in 2024. A prosecutor leading that probe, Mark Pomerantz, resigned in February 2022 after Bragg declined to charge Trump himself with financial crimes. Pomerantz has publicly criticized Bragg's decision not to bring charges and published a book about the investigation. In the biggest trial victory so far in his tenure, his office last December won the conviction of the Trump Organization on tax fraud charges.
[1/2] Workers remove scaffolding at the New York Courthouse at 80 Centre Street where Manhattan District Attorney Alvin Bragg continues his investigation into former U.S. President Donald Trump, in Manhattan, New York City, U.S., March 18, 2023. Trump said on his Truth Social platform that he expected to be arrested on Tuesday and called on his supporters to protest. A prosecutor leading that probe, Mark Pomerantz, resigned in February 2022 after Bragg declined to charge Trump himself for financial crimes. Cohen previously testified that Trump directed him to arrange the payment, and Cohen pleaded guilty in December 2018 to campaign finance violations and other charges. In the biggest trial victory so far in his tenure, his office last December won the conviction of the Trump Organization on tax fraud charges.
Manhattan District Attorney Alvin Bragg has come under political pressure for not bringing charges against Trump earlier, but has now invited Trump to testify before a grand jury, according to Susan Necheles, a lawyer for Trump. The probe comes at a critical time, as Trump is running for the Republican presidential nomination in 2024. A prosecutor leading that probe, Mark Pomerantz, resigned in February 2022 after Bragg declined to charge Trump himself for financial crimes. A spokeswoman for Bragg, who could still decline to charge Trump, referred to Bragg's earlier statement. In the biggest trial victory so far in his tenure, his office last December won the conviction of the Trump Organization on tax fraud charges.
President Joe Biden maintains he cooperated swiftly and completely in returning classified documents. December 20: Biden's personal counsel tells Lausch that an additional batch of documents was discovered in the garage of Biden's residence, in Delaware. Biden's personal counsel tells Lausch that an additional batch of documents was discovered in the garage of Biden's residence, in Delaware. January 12 (morning): Biden's personal counsel informs Lausch that an additional classified document was found at Biden's residence. Biden's personal counsel informs Lausch that an additional classified document was found at Biden's residence.
Loncar shared his 2023 forecast, including new drugs, Nobel Prize winners, and more globalization. Brad Loncar isn't expecting a miraculous rebound for the biotech industry in 2023. In an interview with Insider, Loncar shared 10 predictions for biotech in 2023, ranging from Nobel Prize winners and presidential runs to hot cancer targets and bankruptcy worries. 2022 was a rough year for the biotech industry, which once again underperformed the stock market. The industry runs to the next super-hot cancer target: Claudin 18.2In cancer research, drug companies are always on the hunt for the next promising target.
Forbes reported TikTok's parent company, ByteDance, planned to use the app to surveil Americans. The consumer rights group joins a growing chorus of bipartisan calls to investigate the Beijing-based company. In its Thursday letter, the nonprofit consumer rights group Public Citizen urged the FTC to investigate and "take immediate action against ByteDance and Tiktok" if the reports of surveillance are substantiated. The app's links to the Chinese government have long spurred concerns over propaganda, fake news, and data privacy — with the Trump administration in 2020 even proposing a total ban of TikTok. In 2021, the Biden administration promised a security review of foreign-owned apps, but has yet to publish its results.
Şapte cercetători care au dezvoltat câteva dintre vaccinurile împotriva COVID-19 au fost recompensaţi miercuri cu premiul Prinţesa de Asturias pentru Cercetare Ştiinţifică şi Tehnică pe anul 2021, la care optau 48 de aspiranţi de 17 naţionalităţi, relatează EFE.Cercetătorii recompensaţi sunt biologul ungar Katalin Karikó; imunologul american Drew Weissman; medicii germani Ugur Sahin şi Ozlem Tureci; biologul canadian Derrick Rossi; vaccinologul britanic Sarah Gilbert şi biochimistul american Philip Felgner, scrie agerpres.ro Potrivit deciziei juriului prezidat de fizicianul spaniol activitatea celor şapte cercetători constituie un excelente exemplu al importanţei ştiinţei de bază pentru a ajuta la protejarea sănătăţii la scară globală.Conform membrilor juriului, cercetătorii recompensaţi anul acesta au condus, prin activitatea lor îndelungată în cercetările de bază, la aplicaţii inovatoare precum obţinerea într-un timp extraordinar de scurt, de vaccinuri eficiente pentru a lupta împotriva pandemiei de COVID-19.Decizia juriului arată totodată că dezvoltarea tehnologiei inovatoare a ARN mesager, precum şi producţia de vaccinuri bazate pe adenovirus, deschid calea plină de speranţă spre utilizarea lor în alte boli infecţioase.Anul trecut, matematicienii francezi Yves Meyer şi Emmanuel Candes, belgianca Ingrid Daubechies şi australianul Terence Tao au fost recompensaţi împreună cu acest premiu pentru contribuţiile lor revoluţionare şi importante la teoriile şi tehnicile moderne de procesare matematică a datelor şi semnalelor.Este cel de-al şaselea premiu Prinţesa de Asturias decernat miercurea acestea după premiul pentru Arte acordat artistei sârbe Marina Abramovic, pentru cariera sa de peste 50 de ani în arta performativă, premiul pentru Comunicare şi Ştiinţe Umane acordat ziaristei şi scriitoarei americane Gloria Steinem, simbol al feminismul în SUA; premiului pentru pentru Literatură cu care a fost recompensat Emmanuel Carrere, jurnalist, scriitor, scenarist, critic şi regizor francez şi premiului pentru Cooperare Internaţională, acordat pe 16 iunie organizaţiei CAMFED (Campaign for Female Education o Campana para la Escolarización Femenina) mişcare panafricană ce investeşte în educaţia tinerelor şi a fetelor.Ceremonia de înmânare a premiilor Prinţesa de Asturias va avea lor în octombrie la Oviedo, într-o gală solemnă prezidată de regii Spaniei. Premiile Prinţesa de Asturias sunt atribuite anual unor personalităţi din domenii foarte diverse: arte, cooperare internaţională, ştiinţe sociale, comunicare, sporturi, cercetare ştiinţifică şi litere.Fiecare premiu Prinţesa de Asturias constă într-o reproducere a statuetei concepute de Joan Miro - simbol reprezentativ al premiului - un cec în valoare de 50.000 de euro, o diplomă şi o insignă.
Persons: Katalin Karikó, Drew Weissman, canadian Derrick Rossi, Sarah Gilbert, american Philip Felgner, Yves Meyer, Emmanuel Candes, Ingrid Daubechies, Tao, Gloria, Emmanuel Carrere, Joan Miro Organizations: Education Locations: Asturias, canadian, american, Prinţesa, SUA, francez, Oviedo, Spaniei
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