The Lightning, who beat the host Florida Panthers 3-2 in overtime Friday, improved to 8-2 in their past 10 games against the Islanders.
Devils 2, Sharks 1Yegor Sharangovich and Dawson Mercer scored second-period goals to lead New Jersey to a victory over visiting San Jose.
The Blues controlled the first eight minutes of the game and scored the game's first goal on a power play.
Avalanche 3, Golden Knights 2Nathan MacKinnon, Valeri Nichushkin and Evan Rodrigues scored goals, and visiting Colorado beat Vegas.
He also became the first defenseman in NHL history to begin a season with a five-game goal streak.