DIRS.INFO The most relevant business & tech news

☆ Weight-loss drug Wegovy produces ‘largest benefit ever seen’ for patients with most common form of heart failure, trial finds
▼ + stars: | 2023-08-25 | by ( Meg Tirrell | ) edition.cnn.com time to read: +5 min

There are 64 million people globally living with heart failure, Novo Nordisk said in a statement about the trial results. This type of heart failure accounts for more than half of all cases in the US and is increasing in prevalence, according to Kosiborod and his co-authors. He noted that 80% of patients with this kind of heart failure in the US have obesity or are characterized as overweight. Until recently, the main treatment options for people with this kind of heart failure were diuretics, sometimes called water pills, Kosiborod said. They’re also changing the way researchers think about obesity, and the results in heart failure contribute to that paradigm shift, Kosiborod said.

Persons: Mikhail Kosiborod, ” Kosiborod, Kosiborod, semaglutide, ”, “, Eli Lilly, Dr, Sanjay Gupta, They’re, “ It’s Organizations: CNN, drugmaker Novo Nordisk, New England, of Medicine, Saint, Kansas, European Society of Cardiology, Novo Nordisk, CNN Health Locations: Kansas, Kansas City, Amsterdam

☆ Sedentary time as a kid could mean heart problems as an adult, research shows
▼ + stars: | 2023-08-24 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +5 min

Childhood inactivity may be increasing risk for heart disease later in life, according to new research. The longitudinal study included 766 children and looked at data from ages 11 to 24, the research showed. More sedentary time was associated with increased left ventricle mass in the girls who were followed in the study, according to the new research. “Since it is rare for children to have heart attacks, left ventricular hypertrophy or enlarged heart has been employed as early signs of heart damage,” he said. “An example of such light physical activity is taking a long walk.”Children ages 6 to 17 need about an hour of physical activity a day, according to the US Centers for Disease Control and Prevention.

Persons: ”, Andrew Agbaje, ” Agbaje, Agbaje, Nieca Goldberg, University’s, Goldberg, Andrew Freeman, Freeman, “ Organizations: CNN, CNN’s, European Society of Cardiology’s ESC, University of Eastern Finland’s School of Medicine, University’s Grossman School of Medicine, Jewish Health, US Centers for Disease Control Locations: Amsterdam, York City, New, Denver

☆ Covid-19 linked with higher risk of high blood pressure, study finds
▼ + stars: | 2023-08-21 | by ( Giri Viswanathan | ) edition.cnn.com time to read: +5 min

CNN —When it comes to developing high blood pressure, Covid-19 might play an outsized role, a new study says. Of the hospitalized Covid-19 patients, more than 1 in 5 developed hypertension during their time in the hospital, while actively infected with Covid-19, despite having no history of high blood pressure. However, in comparison with patients who were infected with the flu, Covid-19 patients had worse blood pressure outcomes. Covid-19 patients who had been hospitalized were 2.23 times as likely to develop high blood pressure as hospitalized influenza patients. But scientists are unsure how the Covid-19 virus might trigger new-onset high blood pressure.

Persons: Covid, Dr, Tim Duong, Sanjay Gupta, ” Duong Organizations: CNN, US Centers for Disease Control, CDC, American Heart Association, American College of Cardiology, Albert Einstein College of Medicine, CNN Health Locations: United States, Bronx, New York City, Covid

☆ Pain after a heart attack linked with higher risk of death over next eight years, study finds
▼ + stars: | 2023-08-17 | by ( Jen Christensen | ) edition.cnn.com time to read: +5 min

Someone in the US has a heart attack about every 40 seconds, according to the US Centers for Disease Control and Prevention. Heart disease including heart attack is the leading cause of death in the US, but most people survive their first heart attack and go on to lead a normal life, according to the American Heart Association. Additionally, pain could be a deterrent to lifestyle changes that might lower someone’s risk of another heart attack, such as exercise. Dangas said the new study could remind doctors to pay particular attention to their heart attack patients who talk about pain. Cardiac rehabilitation cuts the risk of death in the five years after a heart attack by about 35%, according to a 2016 study.

Persons: CNN —, George Dangas, ”, Dangas, “, Dr, Sanjay Gupta, they’ll, They’ll, Linda Vixner Organizations: CNN, US Centers for Disease Control, American Heart Association, Sinai Hospital, CNN Health, School of Health, Welfare, Dalarna University, Falun Locations: Sweden, Mount Sinai Queens, New York City, Dalarna

☆ Wegovy could prevent up to 1.5 million heart attacks, strokes over 10 years, study says
▼ + stars: | 2023-08-16 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +3 min

A selection of injector pens for the Wegovy weight loss drug are shown in this photo illustration in Chicago, Illinois, March 31, 2023. Novo Nordisk's blockbuster weight loss injection Wegovy could prevent up to 1.5 million heart attacks, strokes and other cardiovascular events in the U.S. over 10 years, according to a study released this week. Researchers from the University of California, Irvine, also found that Wegovy could result in 43 million fewer Americans with obesity over a decade. An estimated 83 million Americans without established cardiovascular disease would also experience heart health benefits after taking Wegovy for a decade. Wegovy would reduce the risk of serious heart problems in that population by 17.8%, which translates to 1.5 million preventable heart attacks, strokes and other cardiovascular events.

Persons: Novo, Wegovy, Nathan Wong, Ozempic Organizations: University of California, Novo Nordisk, UC, Wall Street, Disease, Nordisk's, Nordisk Locations: Chicago , Illinois, U.S, Irvine, Danish, UC Irvine's

☆ As few as 4,000 steps a day can reduce your risk of death, but more is better
▼ + stars: | 2023-08-08 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +5 min

CNN —Walking a minimum of 4,000 steps a day significantly reduces your risk of an early death, while taking 2,337 steps a day will reduce your risk of death specifically from cardiovascular disease but “more is better,” according to a new meta-analysis of studies. Anything below 5,000 steps a day is considered a “sedentary lifestyle,” according to the study. While approximately 4,000 steps a day was associated with a “significant” reduction in the risk of an early death, the biggest impact on risk occurred when people walked more than 7,000 steps a day, with the most benefit occurring at about 20,000 steps, the study found. Start early and keep it upAdults 60 and older who walked between 6,000 and 10,000 steps a day saw a 42% reduction in risk of early death, while people under 60 who walked between 7,000 and 13,000 steps a day had a 49% reduction in risk, he said. The difference is likely explained by the formula, “the earlier, the better,” Banach said.

Persons: Maciej Banach, David Katz, ”, Katz, “, Banach, Dr Ibadete Bytyçi, ” Banach, Andrew Freeman, Freeman, ‘, ‘ Don’t, ’ Organizations: CNN, European Society of Cardiology, Johns Hopkins University School of Medicine, True Health Initiative, European, Preventive Cardiology, University Clinical, Jewish Health, CNN’s Locations: Baltimore , Maryland, Australia, Japan, Norway, Spain, United Kingdom, United States, Kosovo, Pristina, Denver , Colorado

☆ New in-ear device promises to predict fainting, help understand dizziness and brain fog
▼ + stars: | 2023-06-13 | by ( Ashley Capoot | ) www.cnbc.com time to read: +1 min

Digital health startup STAT Health has designed a device to help people better understand why they're experiencing symptoms like dizziness, fainting and brain fog. STAT Health on Tuesday announced its new in-ear wearable, the STAT, which measures blood flow to the head. Users can track their metrics in an app on their cellphone and glean insights into how their lifestyle choices affect their symptoms. "This population, a lot of doctors actually can't measure that anything is necessarily wrong with them," Lee told CNBC in an interview. Lee said the STAT will help give patients access to real-time insights to help them decide when they can push themselves, and when they should take it easy.

Persons: Daniel Lee, Lee, They're, it's, there's Organizations: Tuesday, American College of Cardiology, STAT, CNBC

☆ See the 18-slide presentation that startup Carta Healthcare used to convince investors to bet $25 million on its approach to saving hospitals money
▼ + stars: | 2023-06-09 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +3 min

Carta Healthcare raised a $25 million Series B from backers like health system Memorial Hermann. That puts startups in need of a Series B round in a tough position. Insider got an exclusive look at the pitch deck Carta Healthcare used to raise $25 million in Series B funding. This article was initially published in November 2022 and has been updated in June following the official close of Carta's Series B. Here's the 18-slide presentation Carta Healthcare used to raise $25 million in Series B funding.

Persons: Hermann, Matt Hollingsworth, Brigham, Hollingsworth, Anna Brody, Carta, hasn't Organizations: Healthcare, Investors, Rock Health, Carta, Memorial Hermann Health, UnityPoint, Paramark Ventures, Frist Cressey Ventures, American College of Cardiology, Asset Management Ventures, Innovation, Mass, Maverick Ventures Investment Fund, Storm Ventures Locations: —, San Francisco

☆ Strong leg muscles may be linked with better outcomes after heart attack, study suggests
▼ + stars: | 2023-05-29 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +5 min

CNN —Growing evidence shows that building muscle strength can have benefits for your heart, even leading to better outcomes after a heart attack. Kamiya said that after a heart attack, medically known as a myocardial infarction, the heart can go through a process called myocardial remodeling or cardiac remodeling, in which fibrous tissue accumulates, causing an enlargement of the heart. But emerging evidence suggests that exercise-based cardiac rehabilitation can alter the course of such remodeling in a way that improves heart function. “Cardiac remodeling is the main cause of the onset of heart failure after myocardial infarction,” Kamiya said. But more can be learned about why some people may be more affected after a heart attack than others, said Dr. Shaline Rao, director of heart failure services at NYU Langone Hospital-Long Island, who was not involved in the new study.

☆ Lower cholesterol with a plant-based diet, study says
▼ + stars: | 2023-05-24 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +5 min

In study particpants, LDL levels dropped 10% and total cholesterol declined 7% for people following a plant-based diet when compared with those who eat both meat and plants, the study found. A plant-based diet can help reduce LDL cholesterol, a new study said. Statin treatment is superior to plant-based diets in reducing fats and cholesterol levels, Frikke-Schmidt said in a statement. In addition, people who transition to a plant-based diet should still be mindful about the kinds of foods they’re consuming. “Not all plant-based diets are equal,” said Aedin Cassidy, professor and director for interdisciplinary research at the Institute for Global Food Security in Queen’s University Belfast, in a statement.

☆ As weight-loss drugs hit the U.S. market, doctors debate how to use them
▼ + stars: | 2023-03-30 | by ( Patrick Wingrove | ) www.reuters.com time to read: +6 min

[1/2] The American Medical Association logo is seen at their office in Washington, D.C., U.S., August 30, 2020. REUTERS/Andrew Kelly/March 30 (Reuters) - As powerful new obesity drugs enter the U.S. market, medical associations are keen to advise their members on how to best use them for patients. "These new compounds are game changers, there's no doubt about it," said Anthony Comuzzie, chief executive of The Obesity Society. The group last provided obesity treatment guidelines in 2013 alongside the American Heart Association and American College of Cardiology. OBESITY AS A DISEASEThe American Medical Association, the nation’s largest medical group, recognized obesity as a disease in 2013.

☆ Merck's drug boosts exercise capacity in pulmonary hypertension patients
▼ + stars: | 2023-03-06 | by ( Khushi Mandowara | ) www.reuters.com time to read: +2 min

Sotatercept, combined with a background therapy, helped patients with pulmonary arterial hypertension to walk about 40.8 meters more in six minutes. J.P. Morgan analyst Chris Schott said the data exceeded the brokerage's expectations and "should confirm the drug as go-to add-on therapy" for pulmonary arterial hypertension. Schott forecast peak sales of $3 billion to $4 billion for the drug. In October, Merck said sotatercept had met the main goal of a late-stage study, but did not release the full data. Reporting by Khushi Mandowara and Pratik Jain in Bengaluru; Editing by Arun Koyyur and Shinjini GanguliOur Standards: The Thomson Reuters Trust Principles.

☆ Top 10 things the Club is watching in the stock market Monday: Stocks look mixed, dueling Disney notes
▼ + stars: | 2023-02-13 | by ( Jeff Marks | ) www.cnbc.com time to read: +4 min

Club holding Caterpillar (CAT) downgraded to neutral (hold) at Baird; price target cut to $230 per share from $290. Disney (DIS), a Club stock, price target is lowered to $130 per share from $145 at Citi; keeps a buy rating following last week's solid earnings and restructuring announcement. Merck (MRK) price target is increased to $125 per share from $120 at Credit Suisse. As a subscriber to the CNBC Investing Club with Jim Cramer, you will receive a trade alert before Jim makes a trade. Jim waits 45 minutes after sending a trade alert before buying or selling a stock in his charitable trust's portfolio.

☆ Fact Check-No evidence for claims FAA updated its pilot ECG guidelines due to COVID-19 vaccine injury
▼ + stars: | 2023-02-03 | by ( Reuters Fact Check | ) www.reuters.com time to read: +5 min

Very concerned.”“After the vaccine rolled out, the FAA secretly widened the EKG parameter range for pilots so they wouldn’t be grounded. A PR interval between 120 and 200 milliseconds (ms) is considered normal, according to standard medical practice (here ). A PR interval greater than 200ms is considered to be a first degree atrioventricular block (AV block), which means that the signals are delayed (though not blocked), as explained (here). According to the American Heart Association (here), "A first-degree heart block occurs when the electrical impulse moves through the heart’s AV node slower than normal. First-degree heart block rarely causes symptoms and may not require treatment."

☆ How AI is detecting heart attack risk and aiming to outsmart America’s No. 1 killer
▼ + stars: | 2023-01-26 | by ( Kerima Greene | ) www.cnbc.com time to read: +7 min

Cleerly founder and CEO James Min, a cardiologist, started the company to find a better way to assess heart health, by applying AI to the problem. Heart disease is the nation's No. CNBC: What are indirect markers of heart disease? Min: Many emergency department visits for heart attacks are preventable if risk factors for heart disease are identified in advance. Using millions of annotated CCTA images, Cleerly algorithms quantify and characterize atherosclerosis and its features.

For decades doctors have been telling their patients that high levels of HDL, otherwise known as “good cholesterol,” could protect them from heart disease. But a new study suggests that having a lot of so-called good cholesterol doesn’t mean a lower risk of heart attacks. The new findings surprised the researchers, who originally designed their study to understand how cholesterol levels in Black and white middle-aged adults without heart disease affected their future risks. Previous research on "good" cholesterol and heart disease consisted of mostly white adults. Low HDL levels were associated with an increased risk of coronary heart disease in white participants, but not Black participants.

☆ Study suggests that HDL or ‘good’ cholesterol is less beneficial than previously thought, especially for Black adults
▼ + stars: | 2022-11-21 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +3 min

Also, higher levels of HDL cholesterol were not found to reduce the risk of cardiovascular disease for either group. “It’s been well accepted that low HDL cholesterol levels are detrimental, regardless of race. The researchers found that high levels of low-density lipoprotein (LDL) cholesterol and triglycerides “modestly” predicted heart disease risk among both Black and White adults. But they suggest that more work is needed to understand what’s driving the racial differences in the link between HDL and heart disease risk. And in the meantime, current clinical assessments for heart disease risk “may misclassify risk in Black adults, potentially hindering optimal cardiovascular disease prevention and management programs for this group,” they wrote.

☆ Predictive value of 'good' cholesterol level varies by race, U.S. study finds
▼ + stars: | 2022-11-21 | by ( Nancy Lapid | ) www.reuters.com time to read: +3 min

In contradiction to what has generally been assumed, low HDL levels did not confer any higher risk of heart disease in Black people, researchers said. Among white people, however, those with HDL levels below 40 milligrams per deciliter had a 22% higher risk for coronary heart disease compared with those whose HDL levels were higher. High HDL levels (above 60 mg/dL), which are thought to be protective, were not linked with lower coronary heart disease risks in either race, researchers found. Participants of both races were similar in age, cholesterol levels, and other heart disease risk factors, the researchers said. The early studies that shaped perceptions about healthy cholesterol levels overwhelmingly involved white American participants, Pamir said.

In October 2021, Da’Vion Miller was found unconscious in the bathroom of his home in Detroit a week after receiving his first dose of Pfizer's Covid vaccine. Courtesy Da’Vion MillerMiller is one of a very small group of people in the United States who have experienced myocarditis following vaccination with the Pfizer-BioNTech or the Moderna Covid vaccines based on mRNA technology. Video: CDC says waiting longer between Covid vaccine doses could reduce myocarditis risk. Cooper joined an expert advisory panel formed by Moderna to monitor its Covid vaccine safety. The Pfizer study will include people who were previously hospitalized with vaccine-associated myocarditis, and it will also follow those who were more recently diagnosed.

☆ Here's an exclusive look at the 18-slide presentation that a health-data startup used to land $20 million as it eyes profitability
▼ + stars: | 2022-11-09 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +2 min

Carta Healthcare just announced $20 million in Series B funding led by Paramark Ventures. That puts startups in need of a Series B round in a tough position. The health-data startup said on November 2 that it had raised a $20 million Series B round led by Paramark Ventures. Insider got an exclusive look at the pitch deck Carta Healthcare used to raise $20 million in Series B funding. Here's the 18-slide presentation Carta Healthcare used to raise $20 million in Series B funding.

An experimental drug could eventually offer hope to millions of people struggling with uncontrolled high blood pressure, new research has found. Overall, 20% to 30% of adults experience high blood pressure, Brown said in an email. Uncontrolled hypertension accounts for 5% to 10% of all people with hypertension. Hypertension is diagnosed when a person has a blood pressure of 130/80, while a systolic measurement of 120-129 mm Hg is considered to be “elevated.” A normal range is less than 120/80 mm Hg. Those who received the highest dose of the medication saw their systolic blood pressure — the top number in the measure — drop an extraordinary 20 points during the study.

☆ Don’t bother with dietary supplements for heart health, study says
▼ + stars: | 2022-11-06 | by ( Jen Christensen | ) edition.cnn.com time to read: +7 min

CNN —Six supplements that people commonly take for heart health don’t help lower “bad” cholesterol or improve cardiovascular health, according to a study published Sunday, but statins did. Some people believe that common dietary supplements – fish oil, garlic, cinnamon, turmeric, plant sterols and red yeast rice – will lower their “bad” cholesterol. The fatty deposits can block the flow of oxygen and blood that the heart needs to work and the blockage can lead to a heart attack or stroke. He calls these supplements “21st century snake oil.”In the United States, the Dietary Supplement and Health Education Act of 1994 sharply limited the US Food and Drug Administration’s ability to regulate supplements. “The good news, we know statins work,” Khera said.

☆ Paxlovid: Covid-19 treatment can interact with common heart medications, doctors warn
▼ + stars: | 2022-10-12 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +5 min

Paxlovid can have dangerous interactions with some of the most common medications for cardiovascular disease, including certain statins and heart failure therapies, a new paper warns. The review paper says that interactions between Paxlovid and certain blood thinners can cause an increased risk of bleeding. Interactions between Paxlovid and some cholesterol medications such as statins can be toxic to the liver, and interactions between Paxlovid and certain blood pressure medications could cause low blood pressure, flushing and swelling. For cardiovascular medications that patients could discontinue in order to take Paxlovid, Morgan noted that the Covid-19 treatment is a five-day regimen. “Awareness of the presence of drug-drug interactions of Paxlovid with common cardiovascular drugs is key.

Consumul zilnic al acestui aliment pe o perioadă de doi ani a redus riscul dezvoltării de boli cardiovasculare la un grup de persoane în vârstă, arată un studiu recent publicat în Journal of the American College of Cardiology. După cum au descoperit cercetătorii americani și spanioli, consumul regulat de nuci reduce riscul dezvoltării bolilor cardiovasculare, arată studiul lor publicat recent în Journal of the American College of Cardiology. Timp de doi ani, un grup de voluntari a mâncat între 30 și 60 de grame de nuci în fiecare zi. Rezultatele studiului au arătat că persoanele din primul grup au înregistrat o scădere considerabilă a biomarkerilor inflamaţiei, care au legătură cu un risc crescut de boli cardiovasculare. Deși beneficiile nucilor pentru inimă au fost deja descoperite, acest studiu a contribuit la înțelegerea acestui efect pozitiv.

Persons: Universitatea Loma Linda Organizations: Journal, BUCUREŞTI, Sputnik, Universitatea Loma Locations: Cardiology, Barcelona, California

Search resuls for: "of Cardiology"

24 mentions found