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Loneliness, social isolation linked with early death
  + stars: | 2023-06-19 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +7 min
The new paper, however, is a meta-analysis of 90 studies that had examined the links between loneliness, social isolation and early death among more than 2 million adults. People who experienced social isolation had a 32% higher risk of dying early from any cause compared with those who weren’t socially isolated. Holt-Lunstad was the lead scientist on the US Surgeon General’s recent advisory report on social isolation and loneliness. Broadening social connectionsPeople experiencing social isolation and loneliness should actively seek social support, Wang said. Public health strategies to address loneliness and social isolation, including raising awareness, are also needed, Wang said.
Persons: Turhan Canli, Canli wasn’t, Julianne Holt, wasn’t, Holt, Lunstad, Anthony Ong, Ong wasn’t, ” Holt, Canli, , ” Canli, Fan Wang, , Ong, Wang Organizations: CNN, Stony Brook University, Brigham Young University in, Center, Integrative Developmental, Human Health Labs, Cornell University, , Harbin Medical University Locations: Brigham Young University in Utah, New York, China
In some cases, patients like Ms. MacKenzie with cancer that has spread inside their bodies — called metastatic disease — are able to stay alive much longer than previously predicted. Until recently, the prevailing wisdom in oncology was that many early-stage cancer patients could be cured, but metastatic disease was almost always incurable. This thinking drove cancer research, treatment and care for decades. Since metastatic disease was usually considered incurable, research focused on early-stage disease. Right now, two relatively new classes of cancer drugs are displacing traditional chemotherapy for many types of cancer and giving metastatic patients, in particular, more time.
Persons: MacKenzie, Oncologists, John McCain —
Who Says a Walk Can’t Be a Workout?
  + stars: | 2023-06-16 | by ( Jancee Dunn | ) www.nytimes.com   time to read: +1 min
This week, we’re making our walk into a workout. A slow, steady pace has been shown to lower the risk of heart disease and diabetes. But research suggests that increasing the length of your walk can lower the risk of premature death and diseases such as cancer — and raising the intensity brings additional benefits. I also took a fitness-focused walk with Martinus Evans, a certified running coach and the founder of Slow AF Run Club. Evans and I explored Prospect Park in Brooklyn, where he reminded me that a workout walk, more than anything else, should be fun.
Persons: Janet Dufek, Martinus Evans, Evans, “ We’re, , Organizations: University of Nevada Locations: Las Vegas, Prospect, Brooklyn
We have also learned over time that not all breast cancer tumors grow or spread at the same rate. For example, a type of breast cancer that I’ve studied, called ductal carcinoma in situ — also known as stage 0 breast cancer — may never progress to invasive disease in a person’s lifetime, and so may require less therapy. Detecting cancer becomes more challenging when trying to distinguish cancer, which also appears white on a mammogram, from dense breast tissue. The task force acknowledged that dense breasts can increase a woman’s risk of breast cancer and that certain race or ethnicity groups are at higher risk for early-onset breast cancer. Black women under 50, for example, die of breast cancer at twice the rate of white women under 50 in the United States.
He’d occasionally noticed blood in his urine and wanted to have that checked out. His doctor ordered a prostate-specific antigen, or P.S.A., test to measure a protein in his blood that might indicate prostate cancer — or a number of more benign conditions. “It came back somewhat elevated,” said Mr. Loree, 68, an instructional designer who lives in Berkeley, Calif. A biopsy found a few cancer cells, “a minuscule amount,” he recalled. Mr. Loree was at very low risk, but nobody likes hearing the c-word. But because his brother and a friend had both been diagnosed with prostate cancer and had undergone aggressive treatment that he preferred to avoid, Mr. Loree felt comfortable with a more conservative approach called active surveillance.
Michel Gaubert first crossed paths with Karl Lagerfeld when he worked at a record store on the Champs-Élysée. “All his life Karl was obsessed with music,” he recalled. All his life Karl was obsessed with music. Then one day Eric came and asked if I wanted to work with the Karl Lagerfeld brand. Karl said Diane de Beauvau-Craon [a French princess and a pal of Mr. Lagerfeld’s] would call me.
Mysteries like cellular senescence, telomere length, and DNA methylation hold the keys to our longevity. But so far, no one has figured out how to completely prevent or eliminate harmful senescent cells. DNA methylation is linked to several age-related diseasesTreating or preventing age-related diseases is one of the keys to unlocking longer, healthier lives. Similar to telomeres, DNA methylation is another way scientists can measure your biological age to help predict your life expectancy. For example, telomere shortening can lead to DNA damage, which in turn disrupts your mitochondria.
A resolution to Johnson & Johnson's outstanding talc litigation claims may finally be here — and that's welcome news for the company and its shareholders. Johnson & Johnson (JNJ) said it will pay $8.9 billion over the next 25 years to resolve all current and future talc claims. But now that J & J has created a path toward resolving its talc litigation at a steep but very manageable cost of $8.9 billion, the overhang pressure should ease. With the J & J talc litigation overhang nearing an end, the stock deserves to trade back to this level at a minimum. In this photo illustration a bottle of Johnson & Johnson baby powder is displayed on a table on November 12, 2021 in San Anselmo, California.
Experts are debating the most effective uses of artificial intelligence as the technology grows. One of the most beneficial use cases so far has been the tech's ability to identify cancer, the NYT reported. The success of using AI to detect cancer in the Hungarian clinics has inspired doctors in England, Scotland, and Finland to also experiment with the technology, per the Times. Companies have been developing such programs for years, as existing artificial intelligence technologies grow increasingly capable of more complex tasks. "An AI-plus-doctor should replace doctor alone, but an AI should not replace the doctor," Peter Kecskemethy, a computer scientist and cofounder of a company that develops the AI programs assisting doctors, told the Times.
I've donated my hair to charity four times, but I don't plan to again because there's less need now. I've donated my hair to charity four times. Human hair wigs usually have to be cut, colored, styled, and fit specifically to the person's head, Hernandez-Salas said. There's just much less demand for human hair wigs than there was years ago. Before she lost her hair, Melore donated it and got a wig from the American Cancer Society all in the same day.
As COVID-19 raged, the House of Representatives voted in 2020 to allow members to vote by proxy. New House Speaker Kevin McCarthy has now ended it. With newfound control of the House, one of McCarthy's first moves was to eliminate proxy voting when finalizing the House rules package. Joined by 20 other GOP representatives, the lawsuit claimed the US Constitution only allowed for in-person voting and that proxy voting was unconstitutional. These trips are generally funded by the federal government, and proxy voting allowed members to vote while abroad on important business.
An experimental treatment for advanced melanoma is poised to be the next major advance in cancer treatment, experts say. Those who got TIL therapy had a 50% reduction in disease progression and death, compared to those who were treated with ipilimumab, the study found. Bruce Hawley and his wife, Laurie, celebrated their third wedding anniversary in 2021 in Vancouver, several years after his TIL therapy. "The chemotherapy knocks down the immune cells to make space for the TIL cells going in," Hwu said. The hope is that TIL therapy will also be used for other solid cancers, not just melanoma, Rosenberg said.
Lacey Adams this past summer was diagnosed with melanoma, marking her third time battling skin cancer. Dr. Adams told The Post that the former president is "a force that really does take the air out of the room." "It was a lot harder than he thought to find a landing spot because of the Trump Effect," Lacey Adams told the newspaper. However, the former surgeon general affirmed that he was "not complaining," but wanted to provide "context" to the situation, according to the newspaper. They saw 'Trump's Surgeon General' and that caused people to discount, dismiss, or just distrust anything that I said in that space," he added.
Prenuvo, a company offering preventive MRI scans, raised a $70 million Series A in October. Some say healthy people probably don't need whole-body scans, which can lead to risky procedures. On October 18, the company, based in Vancouver, British Columbia, said it had raised a $70 million Series A to provide whole-body MRI scans to consumers. The website says the scans are performed by MRI technologists and analyzed by radiologists trained to read Prenuvo scans. PrenuvoWhole-body MRI scans aren't accessible for everyoneSafavi said whole-body MRI scans have been available for more than two decades for people curious about what might be in their bodies undetected.
"We are the Underground Railroad of 'Gattaca' babies and people who want to do genetic stuff with their kids," Malcolm told me. Ellison, meanwhile, who has two children in their 30s, has reportedly resumed having kids — with his 31-year-old girlfriend. "The person of this subculture really sees the pathway to immortality as being through having children," Simone said. The person of this subculture really sees the pathway to immortality as being through having children. Before she met Malcolm, Simone was convinced she wanted to live her life single and child-free.
Before his streetwear brand BrownMill took off, Justis Pitt-Goodson designed, sewed and sold his own bow ties to his middle school peers. In high school, Pitt-Goodson and two friends built the idea for the streetwear brand. The company attracts NBA players as customers and brought in $327,000 in revenue last year, according to documents reviewed by CNBC Make It. Courtesy of Justis Pitt-GoodsonAfter befriending his two future business partners, Taha Shimou and Kwaku Agyemang, in high school, Pitt-Goodson studied business management at Rutgers University-Newark. The brand brought in $86,000 in 2020, enabling the founders to put down a $7,000 deposit on a Newark storefront that opened in June 2021.
worse-case, highest-carbon-emission scenario.” (The Intergovernmental Panel on Climate Change is the U.N. body that assesses climate change.) How do we weigh the risks of underreacting to climate change against the risks of overreacting to it? While he’s not an expert on climate change, he has spent decades thinking deeply about every manner of risk. That’s particularly true if climate change is akin to cancer — manageable or curable in its earlier stages, disastrous in its later ones. Maybe, I realized, in assessing my newfound concerns about climate change, my long-held beliefs might provide a solution — look to the market.
She was nearly two decades older than the median age — 68 — for all federal judges, according to an Insider analysis. More than a century later, in the 1920s, future Chief Justice Charles Evans Hughes argued for a mandatory retirement age. In 1954, the Senate passed a resolution proposing a constitutional amendment that'd require retirement at age 75 for federal judges. A recent poll by Insider and Morning Consult found that 71% of 2,210 respondents said the federal judiciary should have a mandatory retirement age. For Scheindlin, the former federal judge in Manhattan, Weinstein was an example of an older judge who was "terrific to his last day."
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