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For these two days, take 25% off select items as well as 15% off select beauty products by using the code CYBER at checkout. Everlane Best of SaleThe deal: Various discounts sitewideLooking to add some classic summer essentials to your wardrobe for the warmer weather? Lands’ End High-Summer SaleThe deal: 50% offHeading to the beach and need a new swimsuit? Our Place Summer SaleThe deal: 20% off select itemsFrom now through July 12, upgrade your cookware collection and take 20% off select items from Our Place for its Summer Sale. Sephora Top Skincare SaleThe deal: Up to 50% off top skincare itemsYou can save up to 50% off top skincare picks through July 15.
Persons: Bellamy Richardson, Alex Mill, , Cabeau, Peter Thomas Roth, Huckberry, Ripstop, Macy’s, Michael Kors, you’ve, Samsonite, Spinner —, , LUNA, Pearl Pink, Kate Somerville, grillers, Gray Organizations: Amazon, Amazon Prime, USA, GOLS, Stainless Steel, Macbook, Walmart, Target, Samsung, LG, Sony, LG Smart, Brooklinen, Cabeau, Soho, Rockies, Black, Nike, Nike Air Max, Saks, Saks Fifth, Sale, Sun, Dyson, Lenovo, Thermoworks, Savings, Urban, Big Deal, Urban Outfitters, Party Locations: California, Kalamata, Bone, Zion, Black, Caribbean, Tres, Wayfair, White
CNN —If TikTok and Reddit influencers are to be believed, the plant-based compound called berberine can be a replacement for such popular diabetes and weight loss drugs as Ozempic and Wegovy. Is berberine’s weight loss effect meaningful? Berberine may enhance the body’s natural production of GLP-1, or glucagon-like peptide 1, a gastrointestinal hormone that’s used in Ozempic and other new weight loss drugs. However, in terms of its weight loss benefits, they are modest at best,” he said. “Metformin lowers blood sugar, and berberine lowers blood sugar,” Levitt said.
Persons: Berberine, , , Caroline Apovian, Justin Ryder, Ryder, Joshua Levitt, Ashurbanipal, ” Levitt, Gaston Ernesto Gonzalez Avila, Levitt Organizations: CNN, US Food and Drug Administration, Harvard Medical School, Center, Weight Management, Wellness, Brigham, Women’s Hospital, Northwestern University’s Feinberg School of Medicine, BMI, National Library of Medicine, FDA, American Chemical Society Locations: Boston, Chicago, Ayurveda, Hamden , Connecticut
REUTERS/Johanna Geron/File PhotoJune 1 (Reuters) - Pfizer Inc (PFE.N) said on Thursday data from late-stage trials showed its experimental combination of antibiotics was effective in treating deadly infections caused by drug-resistant bacteria. Deaths from antibiotic-resistant bacteria, also known as superbugs, have been on the rise globally, and health regulators have called for the development of newer treatments as resistance to older antibiotics grows. The late-stage studies compared the experimental combination of the antibiotics aztreonam-avibactam (ATM-AVI) and existing generic drug metronidazole with a combination of two older antibiotics - meropenem and colistin - to treat complicated intra-abdominal infections and types of hospital-acquired pneumonia. Pfizer said the data from the studies shows the antibiotic combination of ATM-AVI is effective and well-tolerated in treating infections caused by gram-negative bacteria. For patients with types of hospital-acquired pneumonia and ventilator‐associated pneumonia, the cure rate was 45.9% for Pfizer's antibiotic combination with metronidazole, versus 41.7% for other, older treatments.
Persons: Johanna Geron, Leroy Leo, Sriparna Roy, Pooja Desai Organizations: Pfizer, REUTERS, Pfizer Inc, Disease Control, Thomson Locations: Puurs, Belgium, United States, Bengaluru
These Are the Best Pillows for Stomach Sleepers
  + stars: | 2023-05-03 | by ( ) www.wsj.com   time to read: +16 min
By Lisa LombardiIf you’re a stomach sleeper, you’ve likely shopped for squishy, soft pillows in the past. That’s why finding the ideal pillow for stomach sleepers can prove to be difficult. It cushioned my head without allowing it to collapse into the mattress, like some other soft pillows do. Best upgrade pillow for stomach sleepersCozy Earth Silk Pillow $224 at Cozy Earth $ 299 Save $ 75 Silk-filled with a breathable bamboo cover, this pillow is a luxe pick for stomach sleepers who tend to overheat while they sleep. This flexibility proves particularly helpful for stomach sleepers, since getting the right loft is important to avoiding neck discomfort.
12 Best Gifts for a First-Time Dad
  + stars: | 2023-04-11 | by ( ) www.wsj.com   time to read: +7 min
Here are 12 of the best first Father’s Day gift ideas. For the stylish dadFew things are more adorable than teeny baby shoes—especially when they’re paired up with a practically identical pair of kicks for Dad to wear as well. For the sentimental dadGo ahead, pull on the heartstrings—a sentimental gift makes perfect sense, especially for an occasion like Father’s Day. The cap comes in 14 color combinations and can even be personalized with a different word or phrase of your choice. “It’ll make a great prop or photo opp, and you can’t have too many cute new parent pictures!” she says.
Persons: Sarah Grossbart, Rachel Simon You, , Paul Zahn, they’re, Adidas Stan Smith, Lindsay Roberts Schey, “ it’s, Alison Deyette, Josh McBride, Nick Guy, Steve Greenberg, it’s, Kimberly Wolf, Roberts Schey, Beau, , Elisabeth Jones, Hennessy, GiftMeChic, Hannah Redmond, , Comfort, Deyette, ” Wolf Organizations: Polaroid, Adidas Locations: Los Angeles, New York City, Houston, Kiehl’s
[1/2] Former Italian Prime Minister and leader of the Forza Italia (Go Italy!) party Silvio Berlusconi attends a rally in Rome, Italy, April 9, 2022. REUTERS/Remo CasilliMILAN, April 10 (Reuters) - Former Italian Prime Minister Silvio Berlusconi's health condition is steadily improving as he is treated in hospital for a lung infection caused by chronic leukaemia, his doctors said on Monday. Doctors later revealed that Berlusconi had been suffering from Chronic Myelomonocytic Leukaemia (CML) "for some time" and that he had recently developed a pulmonary infection. "Cytoreductive, antimicrobial and anti-inflammatory therapies are producing the expected results, allowing us to express a cautious optimism," Zangrillo and Ciceri said.
More than 12 million courses of Paxlovid have been delivered to pharmacies across the U.S., according to federal data. The FDA staff reviewed Pfizer's mid-to-late stage clinical trials of Paxlovid. In one trial called EPIC-HR, Paxlovid showed an 86% reduction in the risk of hospitalization or death in high-risk adults who hadn't received a Covid vaccine. Paxlovid has been plagued by reports of "rebound" Covid infections, where patients see their Covid symptoms or a positive test return after finishing a five-day course of the oral drug. That was also regardless of patients' risk of severe disease, or whether Covid's omicron variant or an earlier strain was dominant, according to the staff.
Oura Inc. and Oura Health are in a legal battle over their names. Last March, Oura Health filed a petition with the Trademark Trial and Appeal Board to cancel Oura Inc.'s trademark, claiming that the trademark could dilute Oura Health's brand and confuse consumers. If Oura Health prevails, Oura Inc. could lose its federal trademark, which would make it difficult to continue running the business without changing its name. Oura Health told Insider that both companies operate in the health and wellness industry, thus creating confusion. A representative for Oura Health said in a statement: "We first used our Oura mark long before Oura Inc. or Ouragin, Inc. were formed.
The United Nations warns that disease-causing bacteria are evolving their drug resistance in ways that threaten people and animal health. Curbing the spread of drug-resistant pathogens will require big changes to how people grow food and treat diseases, the United Nations said. The U.N. said Tuesday that disease-causing bacteria, fungi and other microorganisms—commonly known as superbugs—are developing resistance to drugs in ways that threaten agricultural production and animal health, as well as people. Deaths from drug-resistant infections could rise from one million to 10 million annually by 2050 if antimicrobial resistance continues unchecked, the report said.
Scientists at Auburn University injected alligator DNA into farm-raised catfish. They hope the new and less disease-prone catfish will one day be sold for human consumption. A group of scientists at Auburn University published a paper in January detailing their efforts to genetically modify catfish with the cathelicidin gene of an alligator. The gene, which was added using CRISPR, heightened disease resistance among the catfish in comparison to wild catfish. However, researchers hope that the alligator and catfish gene-editing can be used in tandem with other catfish breeding techniques to help farmers with their catfish yields.
The beauty startup Alleyoop shared part of the application it used to earn $230,000 in tax credits. AlleyoopIn its application, Alleyoop said that Kashani, who leads product development, and other technical personnel met the program's criteria in designing "a state-of-the-art all-in-one portable razor." It described creating 3D models during product development and determining the best materials to "maximize protection from pathogens while maintaining the product's functionality." Concept FormationMany of these solutions required the Project Team to design products that met extremely narrow spatial specifications. R&D ObjectivesSphynx's objectives required the Project Team to design and research new ideas and transform them into viable prototypes suitable for testing out hypotheses regarding design parameters.
Luckily, I got into the one pharmacy school I applied to in the area and got my PharmD — a doctorate of pharmacy. I used student loans to pay for pharmacy school, and because my school was private, I had to take out as much loans as a dentist or a physician, but my pharmacist salary was only a fraction of what they make. Pharmacists can take many clinical roles in a hospitalThere are infectious-disease pharmacists, cardiology pharmacists, transplant pharmacists, and critical-care pharmacists. As a clinical pharmacist, I'd do rounds with the physicians in the morning, weighing in on the drug regimens the patients were on. Hospital pharmacists usually need to work every other weekend.
Pepto-Bismol, the familiar pink over-the-counter medicine, might be expected to ease diarrhea symptoms in people with or without COVID-19. The claim that “big pharma” is hiding the benefits of Pepto-Bismol as a treatment for COVID-19 is part of a narrative that COVID-19 was manufactured for the pharmaceutical industry as a source of profit, previously debunked by Reuters (here). Bruce Yacyshyn, an adjunct professor at the University of Cincinnati and co-principal investigator of the Pepto-Bismol clinical trial, told Reuters via email that there was a valid scientific reason to test the medication in the context of COVID-19. But it remained as yet an “unproven treatment” for the virus because “no placebo controlled, randomized clinical trial data is yet available for this drug in this indication.”WHY PEPTO-BISMOL? There is no scientific evidence that Pepto-Bismol provides any benefit as a treatment for COVID-19, and a clinical trial testing that question has not yet produced results.
LONDON, Dec 9 (Reuters) - Increased drug resistance in bacteria causing bloodstream infections, including against last-resort antibiotics, was seen in the first year of the coronavirus pandemic, a World Health Organization report based on data from 87 countries in 2020 showed. High levels (above 50%) of resistance have been reported in bacteria that typically cause life-threatening bloodstream infections in hospitals such as Klebsiella pneumoniae and Acinetobacter spp, report authors highlighted on Friday. These infections often require treatment with 'last-resort' antibiotics, drugs that are used when all other antibiotics fail. About 8% of bloodstream infections caused by Klebsiella pneumoniae grew resistant to a vital last-resort group of drugs called carbapenems, the report said. Rates of antimicrobial resistance (AMR) remain very high, but last-resort antibiotics are only just starting to lose potency, said Dr Carmem Pessoa-Silva, the lead for WHO Global Antimicrobial Resistance Surveillance System, in a media conference.
Period underwear FAQS — answered
  + stars: | 2022-12-08 | by ( Kristen Rogers | ) edition.cnn.com   time to read: +8 min
Period underwear has grown popular over the past few years for several reasons. Period underwear brands offer a variety of absorbencies since people have different flows. Does period underwear affect symptoms and period length? Some people on social media platforms and product reviews have reported a lighter flow or shorter period while wearing period underwear. “People should be able to access and use whatever type of period management tools that work best for them, including period underwear,” Brandi said.
Many of these sales — most of which run through Cyber Monday — offer plenty of discounted items under $100. SKIP AHEAD Best Cyber Monday deals under $100 | Best Cyber Monday sales under $100To help you make the most of the shopping holiday, we compiled some of the best early Cyber Monday deals and sales under $100 that we think you’ll want to know about. Best Cyber Monday 2022 deals under $100Below, we’re sharing the best Cyber Monday deals under $100 based on our previous coverage and reporting. 4.7-star average rating from 10,573 reviews on AmazonThis All-Clad two-piece cookware set comes with 8-inch and 10-inch non-stick frying pans. Best early Cyber Monday 2022 sales under $100Here are the best early Cyber Monday sales under$100 that we think you’ll want to know about.
On social media, families say they’ve hunted for hours for Tamiflu and the first-line antibiotics amoxicillin and Augmentin. They have one viral illness after another. According to the US Centers for Disease Control and Prevention, more than half of US states have “high” or “very high” respiratory virus activity. As for the antibiotics amoxicillin and Augmentin – a combination of amoxicillin and clavulanate, an agent that helps guard against antibiotic resistance – it’s not entirely clear why demand is so high. Some viral illness, like influenza, can leave the body more vulnerable to secondary bacterial infections that may need treatment with antibiotics.
Data showed that in Europe last year, reported cases of the Acinetobacter bacteria group more than doubled compared with pre-pandemic annual numbers. Some scientists link the rise in hospital-acquired superbug infections during the pandemic to wider antibiotic prescriptions to treat COVID-19 and other bacterial infections during long hospital stays. He also said the data showed decreases in cases of some other common superbugs in European hospitals. The European report is consistent with a trend noted last year in the United States, where government data showed that U.S. deaths from drug-resistant infections jumped 15% in 2020. Experts call superbug infections, including fungal pathogens, a silent pandemic that causes more than a million deaths annually but does not draw attendant focus or funding for research.
It would be the first new pill to treat uncomplicated UTIs in 20 years, GSK said. The drug, called gepotidacin, could become the first new oral antibiotic for uncomplicated UTIs in more than two decades, according to the company. GSK's drug was tested in uncomplicated UTIs, which are restricted to the the bladder and urethra and are generally less serious than complicated UTIs. On Thursday, GSK said two studies enrolled over 3,000 patients with uncomplicated UTIs. GSK, on the other hand, paid $66 million in September to license another antibiotic program being tested to treat complicated UTIs.
SKIP AHEAD Best scalp acne treatments | Common causes of scalp acne and how to treat itBest and worst ingredients for scalp acneClarifying shampoos help to remove buildup on your scalp, said board-certified dermatologist Dr. Jessie Cheung, MD, and look out for ingredients like salicylic acid. Regardless of which product you use, Cheung noted that you may notice a drying effect “immediately,” but scalp acne can take a few days to heal. Witch hazel and peppermint oil help soothe the scalp and remove excess oil, according to Zeichner, which can improve both flakes and scalp acne. Scalp acne: Common causes and how to treat itTucked under your hair, scalp acne might not be as glaring as a huge zit on your nose, but it’s still a nuisance. The bad news is that if your scalp acne is genetic or hormonal, it's a bit trickier to remedy.
LONDON, Oct 25 (Reuters) - The World Health Organization has drawn up the first ever list of fungal pathogens posing the greatest threat to human health, warning that some strains are increasingly drug-resistant and becoming more widespread. The U.N. body, which has similar lists for viruses and bacteria, said fungal infections and their increasing resistance to treatment were a growing risk. Fungal infections often strike people who are already severely ill, like cancer or tuberculosis patients, and rates jumped among hospitalized COVID-19 patients during the pandemic. The list divides the pathogens into three categories based on their potential impact and data on their resistance risk: critical, high and medium priority. The medium group lists a number of other fungi, including Coccidioides spp and Cryptococcus gattii.
Vibrio vulnificus causes an estimated 80,000 illnesses and 100 deaths in the United States every year, according to the US Centers for Disease Control and Prevention. Vibrio vulnificus is one of the bacteria that can cause what’s commonly known as a flesh-eating infection. Vibrio vulnificus infection is the leading cause of death related to eating seafood in the United States. With skin infections, a doctor will first take samples from the infected area to determine if Vibrio vulnificus is what’s causing the problem. Up to 50% of Vibrio vulnificus infections don’t respond to certain antibiotics anymore, studies show.
Zoono USA and Zoono Holdings were collectively fined $325,000. The EPA has reached settlements with the two companies: Zoono USA will pay a $205,000 civil penalty and Zoono Holdings will pay $120,000. Zoono USA and Zoono Holdings are owned by the New Zealand company Zoono Group. "Zoono Holdings takes regulatory responsibilities very seriously and as soon as Zoono Holdings received notification from the E.P.A. Zoono Group, Zoono USA, and United Airlines didn't immediately respond to Insider's requests for comment.
How to Shop for an Ergonomic Office Chair
  + stars: | 2022-06-05 | by ( ) www.wsj.com   time to read: +11 min
Not only does it come in three sizes, but it is also exceptionally adjustable (think seat height, seat tilt, lumbar support and armrests). It’s an especially chic white ergonomic office chair option, but if you’re not loving the leatherette, spring for Italian leather instead (about $200 more). So Via, a Las Vegas-based manufacturer of commercial office furniture, introduced a handful of their made-in-the-U.S. ergonomic chairs to the home market. “It has been the greatest decision,” the designer says of her Herman Miller ergonomic chair. In a perfect world, you’ll find an ergonomic chair with adjustable armrests, but your desk can provide that arm support too.
Probioticele stimulează în mod direct imunitatea prin creșterea producției de limfocite, lucru care întărește sistemul imunitar și permite un răspuns rapid la infecții. Doză zilnică recomandată este de 10-25 de mg.Vitamina DStresul și nivelul ridicat de cortizol sunt asociate cu un risc crescut de infecții virale. În alimentație, vitamina D se găsește în carnea de peste, în gălbenușul de ou, în lapte și uleiul de cod. Acesta acționează atât că un bun expectorant și agent antiviral și totodată că un antioxidant ce ajută la eliminarea toxinelor și stimularea imunității. – Evita contactul neprotejat cu animalele vii (sălbatice și domestice)Citește și: A murit bunicul Gretei Thunberg, faimoasa activistă de mediu
Persons: . Organizations: Sportul Locations: Coronavirusul, măceșele, cătină, antiparazitic, antimicrobial, Ghimbirul, tușești
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