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AdvertisementTrump's new DOGE commission, tasked with cutting spending, has floated laying off federal workers. Government employees told BI they're preparing by networking and freshening their resumes. President Bill Clinton also attempted to reduce federal spending and improve government efficiency with the National Performance Review, led by federal employees. Clinton's panel similarly succeeded in cutting 300,000 federal workers but only managed to get a quarter of proposals that required legislative action through Congress. One senior official at the Commerce Department told BI they anticipate a civil servant brain drain.

Persons: Donald Trump's, Jesus Soriano, who's, Elon Musk, Vivek Ramaswamy, Ramaswamy, Trump's, Brian Hughes, Vance, Soriano, he's, Ronald Reagan, Grace, Bill Clinton, Joyce Howell, —, it's, we're, lifer, Sheria Smith, I'd, Smith Organizations: of Government Efficiency, Business, of Health, Human Services, National Science Foundation, agency's American Federation of Government Employees, GOP, SpaceX, Roivant Sciences, DOGE, of Housing, Urban Development, Veterans Affairs, Homeland Security, Management, Street, Trump, America, Grace Commission, US Postal Service, Postal Service, Environmental Protection Agency, Food and Drug Administration, FDA, of Labor Statistics, Commerce Department, BI, Department of Education, Education Department, aaltcheck Locations: America

☆ Elon Musk publicized the names of government employees he wants to cut. It’s terrifying federal workers
▼ + stars: | 2024-11-27 | by ( Hadas Gold | Rene Marsh | ) edition.cnn.com time to read: +8 min

Several current federal employees told CNN they’re afraid their lives will be forever changed – including physically threatened – as Musk makes behind-the-scenes bureaucrats into personal targets. “These tactics are aimed at sowing terror and fear at federal employees,” said Everett Kelley, president of the American Federation of Government Employees, which represents more than 800,000 of the 2.3 million civilian federal employees. CNN reached out to all four federal employees who either declined comment or were unable to be reached. Cummings said she already knows of federal employees who “have dedicated their lives to civil service,” already quitting their jobs in anticipation of what’s to come. Ramaswamy did not directly respond to questions about singling out individual federal employees but told CNN: “Most federal employees, like most human beings, are fundamentally good people and deserve to be treated with respect, but the real problem is the bureaucracy.”“Our opponent is not any particular individual.

Persons: Donald Trump, Elon Musk, Vivek Ramaswamy, –, Musk, CNN they’re, ”, Everett Kelley, “ It’s, “, ‘, Mary “ Missy ” Cummings, Tesla, ’, Biden, ” Musk, emojis, ” Kelley, it’s, Missy Cummings, Cummings, Musk’s, Ramaswamy, ” Cummings, “ I’m Organizations: CNN, American Federation of Government Employees, George Mason University, Traffic Safety Administration, Civil, US International Development Finance Corporation, Musk’s Department, Government, of, Tesla Motors, Department of Health, Human Services, HHS, Health, Department of Housing, Urban, DOE, HUD, Twitter, US Navy

☆ Opinion | Kennedy, Bhattacharya and Trump’s Covid Contrarian Cabinet
▼ + stars: | 2024-11-27 | by ( David Wallace-Wells | ) www.nytimes.com time to read: +2 min

To look at the short list of names Donald Trump is hoping to appoint to the country’s leading public health roles, it’s easy to see that Covid-19 has remade the country and its ideological arrangements — but perhaps especially the Republican Party. Robert F. Kennedy Jr., Trump’s pick to lead the Department of Health and Human Services, is the most conspicuous example — a reflexive anti-establishment agitator who has trafficked in conspiracy theories about the origins of AIDS, 5G and especially the dangers of common vaccines. Kennedy has called the Covid vaccines, which have probably saved more than 20 million lives globally, “the deadliest vaccine ever made,” and as recently as during his own presidential campaign, he suggested that the coronavirus might be an “ethnically targeted” bioweapon that preferentially spared Ashkenazi Jews and Chinese people. But the others named for top public health posts, though not transparent cranks, are also Covid contrarians whose most important qualification for these positions are their crusades against the public health establishment during the pandemic period: Stanford’s Jay Bhattacharya to lead the National Institutes of Health, and Johns Hopkins’s Marty Makary to run the Food and Drug Administration. Dave Weldon, Trump’s pick to oversee the Centers for Disease Control and Prevention, was a vocal vaccine skeptic long before the pandemic.

Persons: Donald Trump, Robert F, Kennedy Jr, Kennedy, Barack Obama, Trump, Jay Bhattacharya, Johns Hopkins’s Marty Makary, Dave Weldon, Trump’s Organizations: Republican Party, Department of Health, Human Services, Environmental Protection Agency, National Institutes of Health, and Drug Administration, for Disease Control Locations: Trump

☆ A nutrition researcher shares 5 habits he follows to eat healthy and build muscle during the holidays
▼ + stars: | 2024-11-27 | by ( ) www.businessinsider.com time to read: +4 min

AdvertisementA nutrition and longevity researcher said he uses science to make his holidays fun and healthy. He focuses on building muscle to take advantage of big meals for better gains. He also leans into high-protein and veggie-rich holiday meals, followed by a rich dessert. From making seasonal foods more nutritious to using holidays treats to build muscle, here's his approach to the season. AdvertisementUse big meals to fuel muscle-buildingThe holidays often focus on eating, and treating yourself can be a great opportunity to build muscle, according to Rhodes.

Persons: Chris Rhodes, Rhodes, it's Locations: what's, Brussels

☆ Biden proposes requiring Medicare, Medicaid to cover weight loss drugs
▼ + stars: | 2024-11-26 | by ( Evan Bush | Evan Bush Is A Science Reporter For Nbc News. | ) www.nbcnews.com time to read: +3 min

The Biden administration plans to require Medicare and Medicaid to offer coverage of weight loss medications for patients seeking to treat obesity. Today, a month's supply of weight loss drugs can cost $1,000 or more, according to estimates from a White House official. About 72 million Americans were enrolled in Medicaid as of July, according to the Centers for Medicare & Medicaid Services. Research suggests there are significant disparities in who receives weight loss drugs. Weight loss drugs like Wegovy are injectable medications of semaglutide.

Persons: Dr, Laure DeMattia Organizations: Biden, White, Centers for Disease Control, White House, Centers, Medicare, Medicaid Services, Kaiser Family Foundation . Research, NBC News, Health Affairs Locations: Norman , Oklahoma, U.S

☆ Opinion | I Ran Operation Warp Speed. I’m Concerned About Bird Flu.
▼ + stars: | 2024-11-26 | by ( David A. Kessler | ) www.nytimes.com time to read: +1 min

I was co-leader of Operation Warp Speed, which began in Mr. Trump’s first term to accelerate the development of Covid-19 vaccines. I worked on the purchase and rollout of hundreds of millions of vaccines and on developing antiviral treatments. Now I am back at my job teaching at the medical school at the University of California, San Francisco. I have been monitoring the spread of bird flu, also known as H5N1, and discussing the situation with colleagues around the country. In addition, a child in Alameda County in California with minor respiratory symptoms tested positive for H5N1 recently; it is unclear how the child became infected.

Persons: Donald Trump, Biden, Trump’s Organizations: White, Biden administration’s, University of California Locations: San Francisco, United States, Alameda County, California

☆ Small caps historically outperform even the Santa Claus rally, starting before Thanksgiving
▼ + stars: | 2024-11-26 | by ( Sean Conlon | ) www.cnbc.com time to read: +4 min

The weeks heading into year-end often mark a bullish time for stocks, and smaller companies especially might be poised for outperformance. With that in mind, Jeffrey Hirsch, editor-in-chief of the Stock Trader's Almanac, believes investors should buy small caps from the Tuesday before Thanksgiving this year and hold them until Jan. 3rd, 2025. The tendency for small caps to outperform large caps from mid-December through January, combined with the so-called Santa Claus rally right around Christmas, can bolster small-cap growth stocks, Hirsch said. That rally "rhymes with the post-2016 election move," according to John Hancock Investment Management co-chief investment strategist Emily Roland. He's really focused more on the food companies, eating healthier, vaccine companies and just making sure they're held to the same standards."

Persons: Jeffrey Hirsch, Jan, Hirsch, Santa Claus, Donald Trump's, Russell, What's, Emily Roland, Julie Biel, Kayne Anderson, Biel, Gregg Fisher, Matt Unger, Robert F, Kennedy Jr, Unger, they're Organizations: Stock, CNBC, Regional Banking, John Hancock Investment Management, Quent, Osterweis Opportunity, Trump, Department of Health, Human Services, RFK Locations: Santa

☆ Scientists unravel how squirting cucumbers spew their seeds
▼ + stars: | 2024-11-26 | by ( Mindy Weisberger | ) edition.cnn.com time to read: +7 min

Squirting cucumbers blast their seeds over distances hundreds of times their length, and now scientists know how the plants do it. A squirting cucumber in action is a remarkable sight, but if you blink, you might miss it — the eruption lasts about 0.03 second (30 milliseconds). Squirting cucumbers, also known by the scientific name Ecballium elaterium, are found across the Mediterranean and Europe, and in parts of northern Africa, Australia, Asia and North America. The seeds of a squirting cucumber can reach distances of about 33 feet away from the mother plant. But there’s also much to be learned by studying outliers that receive less attention, such as the squirting cucumber, Hay said.

Persons: Pliny the Elder, Dominic Vella, ”, Angela Hay, Max Planck, Hay, Derek Moulton, Chris Thorogood, “ We’ve, ” Moulton, ” Thorogood, Moulton, Dominic Vella “, Elizabeth Evans, It’s, there’s, “, Mindy Weisberger Organizations: CNN, National Academy of Sciences, Max, Max Planck Institute, Plant Breeding Research, UK’s University of Oxford, Oxford Botanic Garden, Scientific Locations: Roman, Europe, Africa, Australia, Asia, North America, Cologne, Germany, Oxford

☆ Is it OK to pee in the shower? Urologists explain
▼ + stars: | 2024-11-26 | by ( Jocelyn Solis-Moreira | ) edition.cnn.com time to read: +6 min

CNN —Here’s a secret that’s not really a secret — many people pee in the shower. When it comes to going number one in the shower, urologists find it generally safe for both men and women. Still, there are certain scenarios in which using the shower as a makeshift toilet might not be a good idea. Still, she said people should not worry about catching an infection if someone with a UTI peed in a public shower since the shower water would wash the urine away. For people who get the urge to pee when hearing water but have trouble urinating, Shusterman advised seeing a doctor to get evaluated for urinary incontinence.

Persons: CNN —, “, ”, Karyn Eilber, “ It’s, it’s, David Shusterman, Shusterman, ” Eilber, Eilber, that’s, Jocelyn Solis, Moreira Organizations: CNN Locations: Cedars, Sinai, Los Angeles, New York City, New York

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Persons: Erno Laszlo, Erno Laszlo Black, Greta Garbo, Katherine Hepburn, Laszlo, Erno Lazlo, Laszlo Hydra, Erno Laszlo Shake Organizations: Business

☆ Hallucinogenic plants detected in residue from ancient Egyptian mug
▼ + stars: | 2024-11-26 | by ( Ashley Strickland | ) edition.cnn.com time to read: +9 min

CNN —Researchers have discovered the residues of psychedelic drugs, bodily fluids and alcohol inside a 2,000-year-old mug, suggesting that ancient Egyptians imbibed hallucinogenic beverages during rituals. “Religion is one of the most fascinating and puzzling aspects of ancient civilizations,” Tanasi said in a statement. Researchers analyzed a 2,000-year-old Bes mug for chemical and DNA traces. Tanasi scanned the Bes mug to conduct a three-dimensonal study of the vessel. “Inebriation played an important ritual role in some ancient Egyptian festivals, especially festivals associated with the flooding of the Nile,” Barrett said.

Persons: ”, Branko van Oppen, Davide Tanasi, Tanasi, we’ve, “, Bes, ” Tanasi, Cassidy Delamarter, ” van Oppen, Cassidy, Betsy Bryan, Alexander Badawy, Bryan, ” Bryan, Caitie Barrett, Barrett, “ Inebriation, ” Barrett, Hathor, “ Bes Organizations: CNN —, Tampa Museum of Art, Institute for Digital Exploration, University of South, Egyptian Art, Johns Hopkins University, Cornell Locations: Egypt, University of South Florida, Saqqara, Giza, Cornell University’s

☆ Dementia may arrive a decade earlier in men at high risk for heart disease, study finds
▼ + stars: | 2024-11-26 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

CNN —Men at risk for heart disease may develop dementia up to a decade earlier than similarly at-risk women, a new study found. “This is novel finding with significant health implications.”Cardiovascular diseases are the leading cause of death in the world, according to the World Health Organization, and heart disease has been the No. Heart disease risk factors include obesity, diabetes, high blood pressure and cholesterol, along with smoking, drinking too much alcohol and not getting proper exercise and adequate sleep, according to the US Centers for Disease Control and Prevention. “Some observational studies have shown that midlife vascular risk factors, such as hypertension, high cholesterol, and obesity are associated with a higher risk of dementia, but not in late life,” Wei said. “Men have more fat (buildup) lining the internal organs (visceral fat) while women have more fat around the hips (subcutaneous fat),” Edison said.

Persons: ”, Paul Edison, Edison, epidemiologist Jingkai Wei, Wei, ” Wei, Charday Penn, VBM, Gray, ” Edison, “ Organizations: CNN, Imperial College London, World Health Organization, US Centers for Disease Control, Memory Research, University of Texas Health Science Center, Neurology, Neurosurgery, Psychiatry, CNN’s Locations: United States, Houston, midlife

☆ One major challenge facing Trump’s chosen health leaders: Keeping politics separate from science
▼ + stars: | 2024-11-26 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +13 min

A key challenge for all of the Trump administration’s new public health leaders, the experts said, will be keeping politics out of science. CNN has reached out to Nesheiwat and Makary for comment and did not receive a response. Some said that could put them at odds with Kennedy, whom Trump has chosen for the nation’s top health post as HHS secretary. It doesn’t seem that he has much experience working in the field of public health,” said Castrucci, an epidemiologist who is president and CEO of the de Beaumont Foundation, a nonprofit focused on strengthening the US public health system. The US surgeon general typically serves as the voice of the administration’s public health policy while promoting their own agenda of issues that they feel are important to the health of American people.

Persons: Donald Trump’s, Johns Hopkins, CNN —, Janette Nesheiwat, David Weldon, Marty Makary, Makary, Robert F, Kennedy Jr, Weldon, Trump’s, Katie Miller, Trump, Mr, Kennedy, ’ Dr, Ashish Jha, Joe Biden, Jha, “, ” Jha, “ There’s, ” Weldon, ” Dr, Jerome Adams, Weldon’s, ” Adams, Peter Hotez, ” Hotez, “ That’s, ”, Jennifer Nuzzo, Amesh, ” Adalja, Brian Castrucci, he’s, there’s, That’s, ” Castrucci, Paul Offit, Weldon “, you’d, Offit, ” Offit, hasn’t, Hotez, Nesheiwat, Dr, Sanjay Gupta, CNN’s Kaitlan Collins, ” Nuzzo, CNN’s Jacqueline Howard, Brenda Goodman, Meg Tirrell Organizations: CNN, Fox News, US Centers for Disease Control, US Food and Drug Administration, Public, FDA, US Department of Health, Human Services, CDC, Trump, HHS, Brown University’s School of Public Health, White, US Public Health Service, Texas Children’s, Covid, Pandemic, Brown University School of Public Health, Johns Hopkins Center for Health Security, “, de, Foundation, Assurance, Agency for Vaccine, Disease Control, Vaccine Education, Children’s Hospital of Philadelphia, Weldon, Studies, CNN Health, Kennedy’s, RFK Jr, Health Locations: New York, Florida, Weldon, Texas, Tampa, CDC’s

☆ Opinion | Donate This Holiday Season: Long Covid Research Need Your Help
▼ + stars: | 2024-11-26 | by ( Zeynep Tufekci | ) www.nytimes.com time to read: +1 min

This column is part of Times Opinion’s 2024 Giving Guide. Read more about the guide in a note from Times Opinion’s editor, Kathleen Kingsbury. For people with debilitating long Covid, the new year heralds a cruel anniversary: Some are experiencing their fifth year with the agonizing illness. And despite the roughly $1.6 billion that the National Institutes of Health has received for long Covid research, not a single drug has yet been approved for that purpose. Some who had scientific backgrounds created a research subgroup but quickly realized that there was almost no useful information available.

Persons: Read, Kathleen Kingsbury Organizations: National Institutes of Health

☆ 'Pirates of the Caribbean' was one of the biggest franchises of the '00s. Kiera Knightley said the films were the 'making and breaking' of her.
▼ + stars: | 2024-11-26 | by ( Eammon Jacobs | ) www.businessinsider.com time to read: +3 min

AdvertisementKiera Knightley played Elizabeth Swann in the "Pirates of the Caribbean" franchise. Knightley said the films were the reason she "was taken down publicly." Kiera Knightley said that the "Pirates of the Caribbean" franchise made her career, but it was also the reason that she "was taken down publicly." Knightley said she wouldn't appear in another major franchise following her experience with "Pirates of the Caribbean." It's years of your life, you have no control over where you're filming, how long you're filming, what you're filming."

Persons: Kiera Knightley, Elizabeth Swann, Knightley, Orlando Bloom, Johnny Depp, TheNumbers.com, Oscar, " Knightley, Bloom, Will Turner, hadn't, Legolas, Ridley Scott Organizations: Pirates, Disney, Stranger Tides, The Times, Hollywood Locations: Caribbean, London, Kingdom, Antarctica

☆ Romania in shock after little-known, far-right populist enters presidential runoff with most votes
▼ + stars: | 2024-11-25 | by ( Https | Media-Cldnry.S-Nbcnews.Com Image Upload Newscms Ap-Live-Blog-Byline-Image.Png | The Associated Press | ) www.nbcnews.com time to read: +3 min

The political landscape in Romania is reeling after a little-known, far-right populist secured the first round in the presidential election, electoral data showed Monday, going from an obscure candidate to beating the incumbent prime minister. Calin Georgescu, who ran independently, will face off against reformist Elena Lasconi in a runoff in two weeks. Lasconi of the progressive Save Romania Union party, or USR, followed with 19.17%. Between 1999 and 2012, he was a representative for Romania on the national committee of the United Nations Environment Program. Romania will also hold parliamentary elections on Dec. 1 that will determine the country’s next government and prime minister.

Persons: Calin Georgescu, Elena Lasconi, Georgescu, Marcel Ciolacu, George Simion, —, Lasconi Organizations: Romania Union, Social Democratic Party, Alliance, Unity, PSD, Bureau, European Union, NATO, Facebook, Romania, United Nations Environment, Associated Press Locations: Romania, Romania’s, pedology, Ukraine

☆ What’s Going on With All of These Food Recalls?
▼ + stars: | 2024-11-25 | by ( Emily Schmall | ) www.nytimes.com time to read: +1 min

There has been a barrage of bad news about food lately. Ten people died after eating Boar’s Head deli meat in a listeria outbreak that hospitalized dozens of others. This month, there has been a food recall nearly every day. But a closer examination of data on foodborne illnesses and food recalls shows a more complicated picture. “I won’t say the food supply is getting less safe, but it’s not getting safer either,” said Donald Schaffner, a professor of food science at Rutgers University.

Persons: Robert F, Kennedy Jr, Donald J, it’s, ”, Donald Schaffner Organizations: Rutgers University

☆ Here's how Nvidia CEO Jensen Huang won over his wife
▼ + stars: | 2024-11-25 | by ( Lakshmi Varanasi | Lloyd Lee | ) www.businessinsider.com time to read: +3 min

AdvertisementNvidia CEO Jensen Huang met his wife Lori Huang at Oregon State University. Huang said he promised her he'd be CEO by 30 to ensure she'd marry him. When Jensen Huang met his wife in college, the odds weren't in his favor. Huang said in a 2010 New York Times interview that he also waited tables at Denny's while he was a student. The CEO also credits his wife and daughter with establishing his signature style: the black leather jacket.

Persons: Jensen Huang, Lori Huang, Huang, she'd, he'd, Lori Mills, Spencer, Ryan Patel, Patel Organizations: Oregon State University, Hong Kong University of Science, Technology, OSU College of Engineering's, Nvidia, OSU, Stanford University, New York Times Locations: Madison, Denny's

☆ Nvidia CEO Jensen Huang says we're still several years away from getting an AI we can 'largely trust'
▼ + stars: | 2024-11-25 | by ( Lloyd Lee | ) www.businessinsider.com time to read: +2 min

AdvertisementNvidia CEO Jensen Huang said in a recent interview that today's AI doesn't provide the best answers. "We have to get to a point where the answer that you get, you largely trust," he said. The CEO said we're still "several years away" and that companies will need more computational power. Nvidia CEO Jensen Huang said today's artificial intelligence doesn't provide the best answers and that the world is still "several years away" from an AI we can "largely trust." During the Saturday interview, Huang said that pre-training or training a model on a large, diverse dataset before it's developed to perform a certain task will not be enough.

Persons: Jensen Huang, we're, Huang, ChatGPT, OpenAI Organizations: Nvidia, Hong Kong University of Science & Technology

☆ The 7 most in-demand work-from-anywhere jobs companies are hiring for—some pay over $100,000
▼ + stars: | 2024-11-25 | by ( Morgan Smith | ) www.cnbc.com time to read: +2 min

FlexJobs has identified the most in-demand work-from-anywhere jobs companies are hiring for by analyzing its database to find the highest volume of postings between June and November 2024. Such jobs are competitive: They account for only about 5% of all remote roles, FlexJobs reports. Some of the top companies hiring for work-from-anywhere jobs in the past six months on the platform include Duolingo, Invisible Technologies and the Wikimedia Foundation. Marketing, writing, project management and tech continue to be the fields with the most work-from-anywhere jobs. "For work-from-anywhere roles, employers are increasingly interested in workers who demonstrate advanced abilities, such as higher-level communication skills like negotiation, resourcefulness and problem-solving," Frana says.

Persons: FlexJobs, Toni Frana, Frana Organizations: Employers, CNBC, Technologies, Wikimedia Foundation, Marketing, Communications

☆ Astronauts had to shut down a Russian space station module due to ‘unusual odor’
▼ + stars: | 2024-11-25 | by ( Jackie Wattles | ) edition.cnn.com time to read: +4 min

The odor — along with “droplets” the cosmonauts, or Russian astronauts, said they observed — likely resulted from “outgassing from materials inside the (Russian) Progress spacecraft,” NASA said in a statement to CNN Monday afternoon. “For any detailed information on what caused the unusual odor, please contact (Russian space agency) Roscosmos,” Humphries said. Continuing saga on the ISSNASA said in its Sunday statement that, after the Russian cosmonauts noticed the odor, they shut down the hatch that connects the 16-foot-long and 8.4-foot-wide Poisk module to the rest of the space station. The space station has hosted rotating crews of cosmonauts and astronauts — hailing from more than 20 countries — since the year 2000 in separate but connected Russian and US sections. In addition to Roscosmos, those partners include the Canadian Space Agency, European Space Agency and Japan Aerospace Exploration Agency.

Persons: “, Kelly O, Humphries, NASA’s, ” Humphries, Roscosmos Organizations: CNN, Space, NASA, Space Center, ISS, ISS NASA, Russian, Baikonur, Canadian Space Agency, European Space Agency, Japan Aerospace Exploration Agency, NASA’s Locations: Houston, Kazakhstan, Russian, Zvezda

☆ Romania: Far-right populist Calin Georgescu leads presidential election runoff with most votes
▼ + stars: | 2024-11-25 | by ( Kathy Rose Obrien | Story Associated Press | ) edition.cnn.com time to read: +3 min

Calin Georgescu, who ran independently, will face off against reformist Elena Lasconi in a runoff in two weeks. Georgescu, 62, was ahead after nearly all ballots were counted with around 22.95% of the vote. Lasconi of the progressive Save Romania Union party, or USR, followed with 19.17%. Georgescu, 62, won 43.3% of the vote in Romania’s large diaspora, compared to Lasconi who got 26.8%. Romania will also hold parliamentary elections on Dec. 1 that will determine the country’s next government and prime minister.

Persons: Calin Georgescu, Elena Lasconi, Georgescu, Marcel Ciolacu, George Simion, Lasconi Organizations: Romania Union, Social Democratic Party, Alliance, Unity, PSD, Bureau, European Union, NATO, Facebook, Romania, United Nations Environment, Associated Press Locations: Romania’s, pedology, Romania, Ukraine

☆ Trial of Controversial Alzheimer’s Drug Halted After Disappointing Results
▼ + stars: | 2024-11-25 | by ( Teddy Rosenbluth | More About Teddy Rosenbluth | ) www.nytimes.com time to read: 1 min

Cassava Sciences, a small biotechnology company based in Austin, Texas, announced it would stop the advanced clinical trial for an experimental Alzheimer’s drug, ending a long-contested bid for regulatory approval. The company announced on Monday that the drug, simufilam, did not significantly reduce cognitive decline in people with mild to moderate Alzheimer’s disease in the trial, which enrolled more than 1,900 patients. “The results are disappointing for patients and their families who are living with this disease and physicians who have been looking for novel treatment options,” the company’s chief executive, Richard J. Barry, said in a statement. These results were unsurprising to many dementia researchers, who had questioned why the trial had been allowed to proceed in the first place, since much of the drug’s underlying science had been called into question.

Persons: Richard J, Barry Locations: Austin , Texas

☆ The Philippines' vice president has publicly threatened to assassinate her boss and his wife
▼ + stars: | 2024-11-25 | by ( Matthew Loh | ) www.businessinsider.com time to read: +6 min

Vice President Sara Duterte said on Saturday that she'd spoken to a hitman to kill her boss and his wife. Philippine Vice President Sara Duterte openly threatened on Saturday to assassinate the country's president, marking the deepest fracture yet in an alliance they once formed for the 2022 election. AdvertisementEduardo Año, national security advisor to the president, added that authorities considered Duterte's threat a "matter of national security." But she also blasted the national security council, saying that its responsibilities related to the safety of the country, not a vice president's remarks about a president. AdvertisementA partnership doomed from the startIn the Philippines, the vice president and president are elected separately and don't necessarily hail from the same party or ideology, though Duterte and Marcos positioned themselves as running mates.

Persons: Sara Duterte, Duterte, I've, Ferdinand, Bong Bong, Marcos, you'll, BBM, Liza Araneta, Martin Romualdez, Eduardo Año, Duterte's, Rodrigo Duterte, Ferdinand Marcos Sr, Ronald Holmes, gunning, —, Jorge Tigno, that's, Holmes, Tigno Organizations: of Representatives, voters, De La Salle University, of Education, Lawmakers, University of, Duterte, Senate, Business Locations: Philippines, Manila, China, Southeast

☆ Nestle and Keurig are going all in on customers making iced coffee at home
▼ + stars: | 2024-11-25 | by ( Ramishah Maruf | ) edition.cnn.com time to read: +5 min

New York CNN —Iced coffee just isn’t the same when you make it at home. This year, Keurig Dr Pepper launched a machine that is dedicated to iced coffee, advertising a drink “as cold as the coffee shops” in three minutes or less for $199. But there’s science behind why iced coffee is so much better at coffee shops, and current single-serve espresso machine innovations don’t meet that quality despite their marketing. And iced coffee mania comes at a time when coffee production is at risk of surging prices as factors like climate change could slash the global supply. Almost a quarter of Americans enjoy their coffee cold, according to this fall’s National Coffee Data Trends report.

Persons: Keurig Dr Pepper, Nescafé, ” Christopher Hendon, ” David Rennie, Coffee, Jennifer Creevy, ” Creevy, ”, It’s, ” Rennie, Nestlé, “ It’s, Dr Pepper, they’re, CNN’s Erika Tulfo Organizations: New, New York CNN, Nestle, ”, University of Oregon, CNN, International Coffee Organization, United Nations, Nestlé Coffee, National Coffee Association Locations: New York, Australia, China, Americano

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