DIRS.INFO The most relevant business & tech news

IRVINE, Calif. (AP) — A pit bull puppy that California police believe got into its owners' fentanyl stash was administered an overdose-reversing drug and is recovering, officials said. The dog's owners, a man and a woman, were arrested and could face charges including drug possession and animal cruelty, according to the Irvine Police Department. “Then the female said, ‘Oh, I think my dog is overdosing,’ ” Oldoerp told the Los Angeles Times on Saturday. At the station, officers administered overdose-reversing naloxone to the dog, which made a “pretty quick” turnaround, Oldoerp said. Authorities will hold on to the puppy until there is a hearing to determine whether to give the dog back to its owners, the Times reported.

Persons: Kyle Oldoerp, “, ‘, ” Oldoerp, ”, wasn’t, Oldoerp Organizations: Irvine Police Department, Walmart, Los Angeles Times, Times, Authorities Locations: Calif, California

After being rushed in an ambulance to a hospital, the 15-month-old girl died from a fentanyl overdose. Political Cartoons View All 1148 ImagesIn California, where the Legislature has failed to pass such laws, prosecutors in at least three counties are turning to drunk driving laws to charge parents whose children die from fentanyl overdose. Last month, a Maine woman pleaded guilty to manslaughter after her 14-month-old son’s fentanyl overdose. Prosecutors say the parents, like drunk drivers, knew fentanyl can injure or kill people. The boyfriend and girlfriend were charged with murder after their toddler died of a fentanyl overdose in June 2020.

Persons: — Madison Bernard, Charlotte, didn’t, ”, Charlie Smith, Smith, ” Smith, Jeremy Whitney Frazier, Heather Marie Frazier, Ashley Malloy’s, Karson, Watson advisement, “ I’ve, Daima Calhoun, Alexandra Waite, Collin Pascal Kittrell, Investigators, Allison, Waite, Graham Donath, Allison's, Ryan Hughes, Bernard, Evan Frostick, Frostick, Bernard's, Carla Rodriguez Organizations: Authorities, National District Attorneys Association, Prosecutors, National District, Riverside, Associated Press, Santa Rosa Police Department, Santa Rosa Press Democrat, AP Locations: SANTA ROSA, Calif, California, U.S, Frederick County , Maryland, Maryland, Maine, Riverside , Sonoma, Stanislaus, Riverside County, Riverside, Sonoma County, Santa Rosa

☆ Addiction Treatment Eludes More Than Half of Americans in Need
▼ + stars: | 2023-08-15 | by ( Noah Weiland | More About Noah Weiland | ) www.nytimes.com time to read: +4 min

Why It Matters: Opioid addiction affects every part of American society. Rural and white Americans were the likeliest to report personal or family opioid addiction, but significant percentages of Black, Hispanic, urban and suburban families did, as well. Overdose fatality rates among Black Americans have climbed substantially in recent years, the Centers for Disease Control and Prevention found in a study last year. A third of Americans fear that someone in their family will die of an opioid overdose, researchers discovered. Methadone, another opioid addiction medication that alleviates cravings, is heavily regulated and often difficult for drug users to access and use continuously, prompting repeated calls from addiction physicians and public health experts for easing restrictions.

Persons: KFF, “, —, ”, naloxone, David Fiellin, Biden Organizations: Centers for Disease Control, Yale School of Medicine, AIDS Locations: ”, Georgia, South Carolina

“They were the type to drink beer, not get rowdy or do shots,” he said. When he ran over, he saw that one man’s face had turned yellow and his eyes had rolled back in his head. From behind the bar, Mr. Foehrkolb grabbed Narcan — a nasal-spray version of naloxone, a drug that reverses opioid overdose — then tilted the man’s head back and pushed the plunger to release the dose. Mr. Foehrkolb, still jarred from the experience, returned to his shift. “Not so much at a quiet place where people are just playing games in a corner, casually drinking.”

Persons: Kevin Foehrkolb, ”, Foehrkolb, Narcan, “ Organizations: Kent House Irish Locations: Towson, Md

☆ Nearly 1 in 10 adults in the US has lost a family member to drug overdose, new KFF poll finds
▼ + stars: | 2023-08-15 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +3 min

More than a quarter of adults surveyed say they or a member of their family has been addicted to prescription painkillers or other illegal opioids, and nearly 1 in 10 adults has had a family member die of a drug overdose, the poll found. Nearly 110,000 people died from a drug overdose in 2022, federal data shows – more than any other calendar year. A significant share of people in the US have had close personal experience with the negative effects of addiction, KFF found. The concerns around opioid addiction are particularly prevalent among rural Americans, who were also more likely to say they’ve already experienced the effects. Findings from the KFF survey are based on responses from representative sample of more than 1,300 adults who were interviewed in mid-July.

Persons: KFF, Dr, Sanjay Gupta Organizations: CNN, KFF, US Centers for Disease Control, CNN Health, National Institute on Drug, National Center for Injury Prevention Locations: United States

☆ U.S. FDA approves second over-the-counter opioid overdose reversal drug
▼ + stars: | 2023-07-28 | by ( ) www.cnbc.com time to read: +1 min

Naloxone, packaged with instructions, is one of the items given out by the Baltimore Harm Reduction Coalition outreach workers. The U.S. Food and Drug Administration has approved the prescription-free sale of the second opioid overdose reversal drug, its manufacturer Harm Reduction Therapeutics said on Friday. The approval of the drug, called RiVive, will provide patients with another over-the-counter option in the United States, where drug-related overdose deaths surpassed 100,000 in 2021. Harm Reduction said it anticipates that RiVive will be available early next year, primarily to harm-reduction organizations and state governments. Harm Reduction Therapeutics has partnered with contract drug manufacturer Catalent Inc to manufacture RiVive.

Persons: drugmaker, Michael Hufford, BioSolutions Organizations: Reduction Coalition, U.S . Food, Drug Administration, Therapeutics, Harm, Catalent Inc Locations: Baltimore, U.S, United States

☆ US FDA approves second over-the-counter opioid overdose reversal drug
▼ + stars: | 2023-07-28 | by ( ) www.reuters.com time to read: +1 min

July 28 (Reuters) - The U.S. Food and Drug Administration has approved the prescription-free sale of the second opioid overdose reversal drug, its manufacturer Harm Reduction Therapeutics said on Friday. The approval of the drug, called RiVive, will provide patients with another over-the-counter option in the United States, where drug-related overdose deaths surpassed 100,000 in 2021. Harm Reduction said it anticipates that RiVive will be available early next year, primarily to harm-reduction organizations and state governments. Harm Reduction Therapeutics has partnered with contract drug manufacturer Catalent Inc (CTLT.N) to manufacture RiVive. Reporting by Sriparna Roy and Bhanvi Satija in Bengaluru; Editing by Pooja DesaiOur Standards: The Thomson Reuters Trust Principles.

Persons: drugmaker, Michael Hufford, Sriparna Roy, Bhanvi, Pooja Desai Organizations: U.S . Food, Drug Administration, Therapeutics, Harm, Catalent Inc, Thomson Locations: U.S, United States, Bengaluru

☆ In Phoenix, Firefighters Battle an Invisible Inferno
▼ + stars: | 2023-07-16 | by ( Jack Healy | More About Jack Healy | ) www.nytimes.com time to read: +1 min

On the hottest days, an additional engine is often dispatched to fight fires as a safeguard against the draining heat’s effects on fire crews. After a relatively mild and wet winter and spring, heat calls to the Phoenix Fire Department are higher this summer compared with last year, a department spokeswoman said. The department said it did not yet have precise figures, but a digital readout of all the active fire calls around Phoenix offered a glimpse. At 3 p.m. on Saturday, about one of every 10 calls was from someone overwhelmed by the day’s heat. There was a dehydrated 69-year-old hiker who had to be wheeled off a trail near the cowboy-inflected town of Cave Creek.

Persons: Captain DiCosmo, Deirdre Organizations: Phoenix Fire Department, Phoenix, telltale Locations: Cave

☆ Opioids may not work for back pain, study finds
▼ + stars: | 2023-06-28 | by ( Kristen Rogers | ) edition.cnn.com time to read: +7 min

The authors found that in terms of effects on back and neck pain, opioids weren’t any more helpful than the placebo. More people in the opioid group had ongoing pain at weeks 26 and 52 than in the placebo group. The opioid group had worse mental health scores and more reports of nausea, dizziness and constipation than the placebo group. Opioids and painThe study authors and experts who weren’t involved in the new study have theories on why opioids weren’t found to be more helpful than the placebo. “The good news is most people with acute low back pain and neck pain recover within 6 weeks naturally.”The authors studied nonspecific back or neck pain, which is pain with an unknown cause.

Persons: haven’t, ”, Christine Lin, Lin, Naloxone, ” Lin, weren’t, Mark D, Sullivan, Jane C, Ballantyne, ” Sullivan, ” Dr, John Finkenberg, wasn’t, don’t, Finkenberg, ” Finkenberg Organizations: CNN, American Spine Society, University of Sydney, University of Washington Locations: Australia, Sydney, San Diego

State and local officials have touted the settlements as providing desperately needed relief to communities hit hard by the crisis. But when the money will be paid out, and who will get it, remains far from clear, Reuters has found. Among the states where money is already reaching organizations on the ground are Massachusetts, Kentucky and Arizona. Most states share a significant portion of their total settlement funds with their city and county governments, which make their own independent decisions about how to spend. But in May, the board overseeing the state’s opioid settlement denied a joint application by Challenges and a county health department to fund harm reduction efforts, without explaining its decision.

Persons: Johnson, ”, Brandon Marshall, Julie Burns, Chris Bryan, Glenn Hegar, Lisa Ruzicka, “, Ruzicka, “ I’ve, drugmakers Johnson, Lauren Kestner, Tricia Christensen, –, we’re, ” Marc Burrows, Brendan Pierson, Disha, Alexia Garamfalvi, Claudia Parsons Organizations: Johnson, U.S . Centers for Disease Control, Reuters, District of Columbia, Reuters Graphics Reuters Graphics Reuters, Brown University School of Public Health, Rhode, Texas, Hope Foundation, Walgreens, Alliance, state’s Department of Health, Human Services, Prevention Services, Community Education Group, Alabama Attorney, University of Mississippi Medical, Inc, Thomson, & $ Locations: Massachusetts, Texas, United States, Maryland, Illinois, . Arkansas, Kentucky, Arizona, Rhode, RIZE Massachusetts, RIZE, Kansas, North Carolina, Charlotte, Appalachia, Mississippi, Alabama, New York

[1/3] Paramedics display a dose of the opioid overdose reversal drug Narcan, or Naloxone Hydrochloride, in an ambulance in Peabody, Massachusetts, U.S., August 8, 2017. The figure is up 0.7% from 108,825 overdoses recorded in the 12-month period ending January 2022, according to U.S. data. The U.S. drug overdose death toll crossed the 100,000-mark for the first time in 2021, as the COVID pandemic disrupted medical care and increased mental health problems. U.S. drug overdose deaths rose 13.7% between January 2021 and January 2022 and by 31.4% in the prior 12 months at the height of the pandemic. But the surge in overdose deaths began before the pandemic took hold due to abuse of prescription opioid painkillers and illegal drugs like heroin.

Persons: Brian Snyder, Joe Biden's, Biden, Tom Britton, Stacey McKenna, McKenna, Nandhini Srinivasan, Khushi, Bill Berkrot Organizations: REUTERS, U.S . Centers for Disease Control, Prevention, American Addiction Centers, U.S, R Street Institute, D.C, CDC, Thomson Locations: Peabody , Massachusetts, U.S, China, Mexico, Washington, Bengaluru

☆ Opinion | The Drug That Saves Lives Even if It’s Never Used
▼ + stars: | 2023-05-07 | by ( Elizabeth Spiers | ) www.nytimes.com time to read: +2 min

Although the drug has no major adverse effects, until later this year, New York State requires people to get some training before they can administer it. Dr. Avery, the vice chair for addiction psychiatry at Weill Cornell Medicine, had conducted many such trainings, and in his office that day he got right to it. Still, the drug has yet to become a standard part of the public’s tool kit. Dr. Avery, whose research is in negative attitudes toward addiction, says it’s because legal and regulatory issues were only part of the problem. It shapes the language we use to talk about addiction and the responses we think are appropriate.

☆ A former fentanyl user describes the first time she took the illicit drug laced with xylazine as 'the scariest experience of my life'
▼ + stars: | 2023-04-21 | by ( Kelly Burch | ) www.businessinsider.com time to read: +9 min

Opioids contributed to 80,411 overdose deaths in 2021, up from 68,630 deaths in 2020, data from the National Institute on Drug Abuse shows. Xylazine is a sedative that can lead to respiratory and cardiac issuesOpioids, like fentanyl, contributed to more than 80,000 overdose deaths in 2021. Mixing xylazine with fentanyl is particularly problematicMixing xylazine and fentanyl can amplify xylazine's sedative effect and the associated health risks. ReutersThe opioid overdose reversal drug Narcan, also known as naloxone, will not reverse the impact of xylazine, since the drug is not an opioid, according to the DEA. That's because opioids account for nearly 75% of all drug overdose deaths in the US.

☆ FDA Approves Narcan for Non-Prescription Sale
▼ + stars: | 2023-03-29 | by ( Julie Wernau | ) www.wsj.com time to read: 1 min

Narcan is an over-the-counter version of a widely used opioid-reversal nasal spray. People will soon be able to walk into a pharmacy and purchase medication to reverse an opioid overdose alongside other non-prescription items like aspirin and vitamins. The Food and Drug Administration on Wednesday said the overdose reversal medication Narcan could be sold over-the-counter for the first time since the opioid crisis began. Narcan’s manufacturer, Emergent Biosolutions Inc., said the nasal-spray version of the medication naloxone would likely begin appearing on shelves by late summer. Emergent is the first company to gain approval to sell naloxone without a prescription.

☆ FDA Makes Overdose-Reversal Drug Narcan Available Over-the-Counter
▼ + stars: | 2023-03-29 | by ( Julie Wernau | ) www.wsj.com time to read: 1 min

The nasal-spray version of naloxone will likely be available on pharmacy shelves by late summer. People will soon be able to walk into a pharmacy and purchase medication to reverse an opioid overdose alongside other nonprescription items like aspirin and vitamins. The Food and Drug Administration on Wednesday said the overdose reversal medication Narcan could be sold over-the-counter for the first time since the opioid crisis began. Narcan’s manufacturer, Emergent BioSolutions Inc., said the nasal-spray version of the medication naloxone would likely begin appearing on shelves by late summer. Emergent is the first company to gain approval to sell naloxone without a prescription.

☆ US FDA approves first OTC opioid overdose reversal drug
▼ + stars: | 2023-03-29 | by ( ) www.reuters.com time to read: +2 min

[1/2] A box of NARCAN nasal spray is photographed at an outpatient treatment center in Indiana, Pennsylvania, U.S. on August 9, 2017. The approval for OTC use of the naloxone-based nasal spray will help align the federal government's stance with states that have provisions to offer the drug without prescription at pharmacies. Drug-related overdose deaths in the United States rose about 15% year-over-year to more than 100,000 in 2021, as per official data. While the approval puts Emergent ahead in the OTC product race, analysts have said it is not likely to derive significant sales from the approval. Benchmark analyst Robert Wasserman said ahead of the approval that Narcan sales peaked in 2020 and have declined since.

☆ FDA approves over-the-counter sales of lifesaving opioid overdose treatment Narcan nasal spray
▼ + stars: | 2023-03-29 | by ( Spencer Kimball | ) www.cnbc.com time to read: +2 min

The Food and Drug Administration on Wednesday approved sales without a prescription of the nasal spray Narcan to reverse opioid overdoses, a decision that promises to significantly expand access to the lifesaving treatment. The FDA's decision means people will be able to buy the 4 milligram nasal spray in supermarkets, convenience stores, gas stations, vending machines and online. FDA Commissioner Dr. Robert Califf, in a statement, said the agency is encouraging the company to make the nasal spray available as soon as possible at an affordable price. The nasal spray must be administered as soon as an overdose is suspected. Two nasal spray devices typically come in a single package.

☆ The government is cracking down on online prescriptions. Patients with addiction and the startups caring for them are caught up in the fight.
▼ + stars: | 2023-03-27 | by ( Blake Dodge | ) www.businessinsider.com time to read: +9 min

Proposed rules would limit online addiction treatmentIn February, the Drug Enforcement Administration, or DEA, published much-anticipated rules meant to set the record straight on online prescribing. The rules, if implemented, generally don't allow providers to prescribe controlled medications online if they don't see the patients in person. For buprenorphine and other drugs, there's an exception that would allow for initial 30-day prescriptions for online patients. Some patients are flights away from in-person careFor some patients, especially in rural areas, in-person appointments are hard to find. Last year, Alabama passed a new law prohibiting providers from prescribing controlled drugs to patients they hadn't seen in person within the past year.

Feb 15 (Reuters) - Emergent BioSolutions Inc's (EBS.N) over-the-counter version of opioid overdose reversing drug received unanimous support from U.S. Food and Drug Administration's panel of advisers, sending shares of the contract drugmaker up nearly 16% after market. The vote puts the naloxone-based treatment Narcan on track to potentially become the first opioid overdose drug to be sold OTC nationwide. Naloxone rapidly reverses or blocks the effects of an overdose, restoring normal respiration. However, most panelists emphasized that OTC use of the nasal spray was safe and proposed ways to improve its labeling, to avoid using the drug wrong. Signage is seen outside of the Food and Drug Administration (FDA) headquarters in White Oak, Maryland, U.S., August 29, 2020.

☆ FDA advisors recommend over-the-counter use of life-saving opioid overdose treatment Narcan
▼ + stars: | 2023-02-15 | by ( Spencer Kimball | ) www.cnbc.com time to read: +7 min

Narcan nasal spray quickly reverses an overdose from heroin and prescription painkillers. The Food and Drug Administration's independent advisors on Wednesday unanimously recommended over-the-counter use of the nasal spray Narcan to reverse opioid overdoses, which would significantly expand access to the life-saving treatment. Emergent BioSolutions ' Narcan is the most commonly sold treatment for opioid overdoses. Emergent BioSolutions said Narcan would be available for the over-the-counter market by late summer if the FDA approves it next month. Opioid overdose deaths spiked 17% during the pandemic from about 69,000 in 2020 to nearly 81,000 in 2021.

☆ 2 Colorado libraries close after meth contamination
▼ + stars: | 2023-01-16 | by ( The Associated Press | ) www.nbcnews.com time to read: +5 min

ENGLEWOOD, Colo. — For the second time in a month, a Colorado library has closed its doors to clean up methamphetamine contamination. The city of about 33,000 just south of Denver decided to test for the drug after officials in the nearby college town of Boulder closed its main library after finding meth contamination, Harguth said. The group declined to comment on whether drug use has been increasing in libraries, citing a lack of up-to-date data. They also pointed out that standards for how much meth contamination is acceptable were developed with an eye toward homes, where frequent exposure is more likely than in public buildings. The Englewood library has made some changes to help homeless people who go there.

☆ Teva says opioids settlement to move forward in U.S
▼ + stars: | 2023-01-09 | by ( Reuters Staff | ) www.reuters.com time to read: +1 min

The logo of Teva Pharmaceutical Industries is seen in Tel Aviv, Israel February 19, 2019. REUTERS/Amir Cohen(Reuters) -Israeli drugmaker Teva Pharmaceutical Industries Ltd said there was sufficient participation from U.S. states and local authorities to move forward with its nationwide settlement agreement to resolve opioid-related claims and litigation. Teva said on Monday it has either already settled with or confirmed participation from 48 of the 50 states and will continue to pursue participation by the states that are yet to join. The litigation over opioids, which began in 2017, has yielded more than $40 billion in settlements from drugmakers, distributors and pharmacy chains. More than 932,000 people have died since 1999 from a drug overdose, according to Federal data.

The problem was the Neris had switched to a new, high-deductible health insurance plan to save money. The 2010 Affordable Care Act expanded access to health insurance, so companies were faced with covering more people than ever before. But the epinephrine auto-injectors — which deliver a shot of epinephrine and are the only emergency medicine available for life-threatening allergic reactions — usually are not. But AHIP (formerly known as America’s Health Insurance Plans), a group that represents such companies, said drug manufacturers are to blame. Fight it with your health care provider, fight it with your insurance company.”“No almost never means no in health insurance,” he said.

☆ FDA Fast-Tracks Review of Overdose Drug Naloxone for Use Without Prescription
▼ + stars: | 2022-12-26 | by ( Julie Wernau | ) www.wsj.com time to read: 1 min

A worker with the Brooklyn Community Recovery Center demonstrates how to use an overdose-reversal drug. A pharmaceutical nonprofit was granted priority review from the Food and Drug Administration to make an inexpensive overdose-reversal drug for use without a prescription. Harm Reduction Therapeutics Inc. said its 3 milligram nasal spray naloxone formulation, called Rivive, had three times higher concentration in the blood of 36 participants than naloxone delivered as a shot. The company said Monday that the FDA gave it a target approval date of April 28. The FDA declined to comment.

☆ FDA Fast-Tracks Overdose Drug Naloxone for Use Without Prescription
▼ + stars: | 2022-12-26 | by ( Julie Wernau | ) www.wsj.com time to read: 1 min

Search resuls for: "Naloxone"

25 mentions found