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To cardiologist Dr. Steven Nissen of the Cleveland Clinic, who wasn’t involved in the trial but is leading a similar one of tirzepatide, those effects are all evidence of the benefits of weight loss. Tirzepatide has shown greater levels of weight loss than semaglutide in clinical trials, leading many, including Nissen, to hope it will show even stronger cardiovascular benefits. Importantly, participants didn’t have a history of diabetes; a previous trial had shown that treating people with diabetes with a GLP-1 drug, Ozempic, reduced their cardiovascular risk. The Wegovy trial showed that 569 of 8,803 people taking the drug had a heart attack or stroke or died from heart-related causes, or 6.5%. The amount of weight loss seen in the trial, 9.4%, was less than in other studies of Wegovy, which showed average weight loss closer to 15%.
Persons: Ania Jastreboff, Wegovy, Dr, Amit Khera, National Institutes of Health’s Dr, Tiffany M, Powell, Wiley, Eli Lilly, Steven Nissen, wasn’t, ” Nissen, , Tirzepatide, Nissen, Michael Lincoff, Lincoff, , Jastreboff, Sanjay Gupta, hadn’t, “ semaglutide Organizations: CNN, Nordisk’s Wegovy, American Heart Association, Yale Obesity Research Center, University of Texas Southwestern Medical Center Dallas, National Institutes of Health’s, New England, of Medicine, US Food and Drug, Cleveland Clinic, Novo Nordisk, Cleveland, CNN Health Locations: Philadelphia, Powell
Google contends that it dominates the market because its search engine is better than the competition's. The Justice Department sought to show that Google feared Apple might establish its own search engine and worried about losing talent to Apple. In a 2019 email shown in court, Pichai asked to be informed directly whenever a member of Google’s search engine team defected to Apple. The Mountain View, California-based company could be stopped from paying Apple and other companies to make Google the default search engine. “You get up in the morning, you brush your teeth and you search on Google,” Nadella said.
Persons: , Sundar Pichai, Pichai, “ That’s, Trump, Judge Amit Mehta, Satya Nadella, ” Nadella, Michael Liedke Organizations: WASHINGTON, Apple, Department, Justice, Google, McKinsey & Co, Justice Department, Microsoft, Washington D.C, U.S, Associated Press Technology Locations: India, U.S, Washington, View , California
Two experts explain how long it could take until fusion power plants are possible. Fusion plants could theoretically produce almost 4 million times as much energy as burning coal or oil — with none of the carbon emissions. It's what Andrew Christlieb, who is part of a US Department of Energy fusion project at Michigan State University, calls "step zero." The US Department of Energy's Fusion Energy Sciences program has a $763 million budget for 2023, which could grow to over $1 billion next year. Achieving commercial fusion power in two decades won't be quick enough to address many countries' goals of adapting clean energy and limiting global warming by 2035.
Persons: It's, Andrew Christlieb, Christlieb, Michael Livingston, PPPL, Jean, Paul Pelissier, it's, Jason Laurea, Lawrence, Jonathan Menard, Menard, Bill Gates, Sam Altman Organizations: Service, Ignition, NIF, US Department of Energy, Michigan State University, Royal Society, Reactor, REUTERS, European Union, Lawrence Livermore National Laboratory, Princeton Plasma Physics, US Department of Energy's Fusion Energy Sciences, Fusion Industry Association, Tech Locations: PPPL, Saint, Durance , Southern France, US, China, Russia, Lawrence Livermore, Princeton
Some left behind prestigious roles to pursue their passions, while others quit tech due to burnout. Some left behind their glamorous roles to pursue their passions, and some quit tech due to burnout. Read more: I quit my six-figure tech job because I couldn't work abroad. Mayuko Inoue left her tech job due to panic attacksMayuko Inoue is a former iOS software engineer at Patreon and Netflix. In 2022, he left Meta to start Taro, a community to help other engineers achieve similar career success.
Persons: Meta would've, , Eric Yu, pinky, Yu, Read, Sergio Najera, Najera, I've, Mayuko Inoue, overexerting, Inoue, that's, Michael Lin, Lin, he'd, — he's, Jerry Lee, Lee, Rahul Pandey, Meta, Taro, Pandey, Mitchie Nguyen, Nguyen, Dayana Sabatin, Sabatin, I'm, it's, Jonathan Javier, Javier, It's Organizations: Meta, Service, Netflix, Google, Facebook, LinkedIn, Cisco Locations: Redding , California, San Francisco, Minneapolis, Minnesota, Spain, Morocco, Netherlands, Argentina, Brazil, Chile, Silicon, Europe, Asia, Seattle, Los Angeles
SPREAD TOO THINA major drawback for potential green hydrogen users is that there has been too little of the stuff available to allow for much real world testing. Yet these train systems have occupied the time and attention of hydrogen system developers that may have been better spent elsewhere. And as heat pumps have been making rapid inroads into home heating markets across Europe and elsewhere in recent years - at a fraction of the cost of a potential hydrogen set up - it is clear that household hydrogen applications will remain scarce. LADDERING UPThe most promising areas for potential hydrogen use have been highlighted by industry analyst Michael Liebreich in his so-called Hydrogen Ladder. Rather than attempt to deploy hydrogen against lower-cost options in homes and transport systems, Liebreich suggests that the hydrogen industry pursue demand opportunities in helping heavy industry to decarbonise.
Persons: Michael Liebreich, Gavin Maguire, Stephen Coates Organizations: International Energy Agency, Reuters, Thomson Locations: LITTLETON , Colorado, Germany, Europe
If you're not shopping for a new office right now, you might be missing out. With vacancies rising, many office landlords are doing whatever it takes to get leases signed, including dropping rents. Risa Letowsky, the co-chair of Adler & Stachenfeld LLP leasing practice group, told Insider that flexibility is the difference between successful and struggling landlords right now. See below for a list of the 10 top perks that office landlords are offering. Flexible lease lengthsThe traditional office lease is eight to ten years.
Persons: Risa Letowsky, aren't, Letowsky, Mike Watts, Andrew Lustgarten, Michael T, Cohen, Franklin Wallach, Carlos Avila Gonzalez, they're, Lustgarten, Watts, Matt Petit, Michael Lirtzman, Lirtzman Organizations: Adler, Stachenfeld, it's, Colliers, San Francisco, Getty, Silverstein Locations: Los Angeles, New York City, San Francisco , California, LA, Chicago
Now may be the time to shop for an office lease. As office vacancies soar to record highs in some markets, office landlords often have no choice but to find new and creative ways to attract new clients. "When you have 55-year-old managing partners of a law firm looking for office space, and they see the golf simulator, they get pretty excited," he said. Long-term leases, which usually feature landlord-financed renovations to the office space, are now being offered with lease-termination options. Office landlords without access to this capital level are often left with only one lever: renting below market price.
Persons: Michael Cohen, Michael Lirtzman, Anthony Tahlier, Andrew Lustgarten, Lirtzman, Sterling, Lustgarten, it's, Matt Petit, Goldman Sachs, Risa Letowsky, Letowsky, Watts, Tishman Speyer, aren't, That's, Cohen, they've, he's, hasn't Organizations: Colliers, Kastle Systems, West Chicago, Sterling Bay's, Century, El, New, Palm, Chase, Wall, JPMorgan, Deutsche Bank, Adler, Stachenfeld, Silverstein, Lawyer Locations: Chicago, Bian, Sterling, Los Angeles, New York, Miami, Liberty, Chase Manhattan, Alamo, CBRE, Los Angeles and New York, LA, United States
Wells Fargo Bank branch is seen in New York City, U.S., March 17, 2020. REUTERS/Jeenah Moon Acquire Licensing RightsNEW YORK, Oct 12 (Reuters) - Wells Fargo (WFC.N) will expand access to a financial planning tool to its nearly 70 million customers after initially offering it to wealth clients earlier this year, the bank said on Thursday. The Life Sync tool allows mobile users to set and track financial goals, check their credit scores and connect with financial advisers. "We already have around 100,000 goals" set on the tool, which account for $24 billion in financial plans, said Michael Liersch, head of advice and planning at Wells Fargo. Wells Fargo, the fourth largest U.S. bank, will report its third-quarter earnings on Friday.
Persons: Wells, Michael Liersch, Michelle Moore, Nupur Anand, Lananh Nguyen, Cynthia Osterman Organizations: REUTERS, Rival Bank of America's, U.S, Thomson Locations: Wells Fargo Bank, New York City, U.S, Wells Fargo, New York
Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailWe are beginning to enter a so-called 'debt doom loop', says Cato Institute's Romina BocciaRomina Boccia, Cato Institute director of budget and entitlement policy, and Michael Linden, Washington Center For Equitable Growth senior policy fellow and former OMB executive associate director in the Biden administration, join 'Squawk Box' to discuss the latest negotiations on Congress, the impact of a potential shutdown on the markets and economy, and more.
Persons: Cato Institute's, Boccia, Michael Linden, Biden Organizations: Cato Institute, Washington Center, Equitable Growth
“It is no secret that Apple is making more money on Bing existing than Bing does,’’ Mikhail Parakhin, Microsoft’s chief of advertising and web services, said in U.S. District Court in Washington. Parakhin was describing Microsoft’s years of futility trying to supplant Google on Apple devices. The U.S. Department of Justice accuses Google of using similar agreements to lock out rival search engines such as Bing and Yahoo, stifling innovation. Asked by U.S. District Judge Amit Mehta whether a search engine could be built solely off machine learning, he replied: "We’ve seen companies try. One option would be to bar the Mountain View, California-based company from paying Apple and others to make Google the default search engine.
Persons: Apple, Microsoft’s Bing, Bing, , Mikhail Parakhin, Parakhin, Ken Smurzynski, Smurzynski, Satya Nadella, Nadella, Judge Amit Mehta, Mehta, Michael Liedtke Organizations: WASHINGTON, Google, Microsoft, Apple, U.S . Department of Justice, Bing, Yahoo, U.S, AP Locations: U.S, Washington, , California
There have been some encouraging signs that business travel is rebounding to pre-Covid spending levels sooner than anticipated, according to the Global Business Travel Association . Business travel was essentially shut down during the Covid pandemic, with many predicting a slow slog to revive sales and a landscape that would be permanently changed. Now the organization is predicting global business travel spending will surpass its 2019 spending level of $1.4 trillion in 2024, compared with its earlier forecast of 2026. Some 28% of those who make the business travel decisions and 32% of those in charge of company travel budgets said their workplace will increase business travel in the coming year, Morning Consult found. Of course, the recovery in business travel can also shift if there are changes in the economic environment.
Persons: Lindsey Roeschke, Roeschke, That's, Michael Linenberg, Linenberg, Patrick Scholes, Scholes, — CNBC's Michael Bloom Organizations: Global Business Travel Association . Business, Morning, Deutsche Bank, CNBC, American Airlines, Delta Air Lines, United Airlines, Ryman Hospitality Properties, Ole Opry, Hospitality, Hyatt Hotels Locations: Delta
WASHINGTON (AP) — The U.S. Justice Department pressed ahead with its antitrust case against Google Wednesday, questioning a former employee of the search engine giant about deals he helped negotiate with phone companies in the 2000s. Chris Barton, who worked for Google from 2004 to 2011, testified that he made it a priority to negotiate for Google to be the default search engine on mobile devices. Google counters that it dominates the internet search market because its product is better than the competition. And Barton testified that Google wasn't the only search engine seeking default status with phone companies. Google has emerged as the dominant player in internet searches, accounting for about 90% of the market.
Persons: Chris Barton, Barton, Microsoft's Bing, Trump, Judge Amit Mehta, Sundar Pichai, Larry Page, Eddy, Hal Varian, ____ Michael Liedtke Organizations: WASHINGTON, U.S . Justice Department, Google, Yahoo, Verizon, Justice Department, Inc, Apple Locations: U.S, , California
The new high-end "Pro" versions of the next iPhone are rumored to include a periscope-style telephoto lens. The "Dynamic Island" found on the iPhone 14 Pro models could be making its way all versions of the iPhone 15. If the rumor mill pans out, this year's iPhone 15 Pro and Pro Max may feature a periscope-style telephoto lens that will improve the quality of photos taken from far distances. The iPhone 14 Pro starts at $1,000 while the Pro Max starts at $1,100. One of the biggest anticipated changes that Apple is expected to announce is a new way to charge the iPhone 15 models and future generations.
Persons: Max, Pro Max Organizations: Service, Apple's, Apple, Pro, Analysts Locations: Wall, Silicon, Apple's Cupertino California
A recent sell-off in airline stocks has created an attractive entry point — but investors should be careful about which names they buy, according to Deutsche Bank. Airline stocks have pulled back about 15% since peaking in mid-July, analyst Michael Linenberg told clients in a note released Monday. That comes as investors attempt to gauge how rising fuel prices, increases in domestic capacity and macro economic uncertainty will impact these companies. AAL DAL,UAL YTD mountain The three airlines this year Airline stocks, he said, are discounting a hard economic landing unlike the broader market. High fuel prices have also been a key driver of downward pressure on these stocks, he said.
Persons: Michael Linenberg, Linenberg, AAL DAL, — CNBC's Michael Bloom Organizations: Deutsche Bank . Airline, NYSE Arca, nab, International, Sun Locations: Delta, United, China, Alaska, Allegiant, SkyWest
‘Like a movie’Here's Michael and Isis on the Puerto Rico vacation in 2018. I’m already having a good time with my friends,’” Michael tells CNN Travel today. Michael and Isis’ sister were part of the same extended friend group at college, so he was intrigued to meet Isis. But Isis’ sister was, at first, less convinced. The couple started talking about moving somewhere new together and settled on Dallas, Texas, where they moved in 2019.
Persons: Woods, Michael Bradford, , , who’d, Atlanta , Georgia –, Isis, Isis –, unquote, Isis ’, Michael, Isis Bradford, I’m, , ’ ”, ” Isis, , Michael didn’t, Michael’s, We’re, let’s, ” Michael, she’d, Here's Michael, She’d, he’d, they’d, Isis Bradford Isis, ” “ Organizations: CNN, Caribbean, Concha Renaissance San, Resort, CNN Travel, La Concha, Puerto Rico, Washington D.C, MGM, Vegas Locations: Puerto Rico, Atlanta , Georgia, Condado, La, San Juan, Puerto, Atlanta, Washington, loggerheads, Dallas , Texas, Michael’s, Sintra , Portugal, Las Vegas,
Affirm Holdings Inc. website home screen on a laptop computer in an arranged photograph taken in Little Falls, New Jersey. Here's how the company did:Loss per share: 69 cents vs. 85 cents as expected by analysts, according to Refinitiv. 69 cents vs. 85 cents as expected by analysts, according to Refinitiv. Revenue: $446 million vs. $406 million as expected by analysts, according to Refinitiv. Affirm also gave strong guidance for the fiscal first quarter, projecting $430 million to $455 million in revenue, versus analyst expectations of $430 million.
Persons: Michael Linford, LendingTree's Matt Schulz Organizations: Deutsche Bank Locations: Little Falls , New Jersey, Refinitiv
REUTERS/Matt Mills McKnight Acquire Licensing RightsLUSAKA, Aug 22 (Reuters) - After nearly four decades in oblivion, the Zambian psychedelic rock band WITCH that mesmerised audiences in the 1970s are back with a new album. Interest for Zamrock rose in the 2010s in the West, thanks to the internet and crate-digging producers as Los Angeles-based Now-Again Records re-released several albums of WITCH and other Zamrock artists. Following their comeback, WITCH - which stands for We Intend To Cause Havoc - are now introducing their new album "Zango" with concerts in the United States and Europe. "It's a fusion of traditional music, African music, funk, blues, jazz - it's a fusion of many genres," Chanda said. "Can this thing grow to a level where when someone comes to Zambia, says where can I listen to Zamrock?
Persons: Matt Mills McKnight, Emmanuel " Jagari, Chanda, Zamrock, Patrick Mwondela, Michael Linyama, Chris Mfula, Catherine Schenck, Matt McKnight, Bhargav Acharya, Angus MacSwan Organizations: REUTERS, Rights, Thomson Locations: Seattle , Washington , U.S, Rights LUSAKA, Zambian, Los Angeles, America, Europe, Lusaka, United States, Zimbabwe, Botswana, Zambia, Johannesburg, Seattle
But a series of legal challenges, including a major U.S. Supreme Court ruling, have cast many of those district lines into doubt. Legal experts said the ruling bolsters similar challenges in Georgia and Louisiana, where voting rights groups have argued that Republican-drawn maps marginalized Black voters. In Ohio, the state Supreme Court appears set to alter course after previously finding Republican maps violated the state constitution’s prohibition on gerrymandering. In Wisconsin, the most expensive state Supreme Court election in U.S. history resulted in a new liberal majority. OTHER BATTLESLast month, the Utah Supreme Court heard arguments over the state’s Republican-drawn congressional map, which carved Democratic Salt Lake County into four separate districts.
Persons: reconvenes, Leah Millis, , , Michael Li, University’s, , Kathy Hochul, Janet Protasiewicz Organizations: YORK, House, U.S . Capitol, Republican, REUTERS, Republicans, Census, Supreme, Center for Justice, U.S, Democrat, REPUBLICAN, STATE, Democratic, Ohio’s Republican, DEMOCRATIC, Utah Supreme Locations: New York, Utah, U.S, Washington , U.S, New, Black, Georgia, Louisiana, North Carolina, Ohio, In Wisconsin, Democratic Salt Lake County, New Mexico
The analyst lowered his price target to $38 from $52, still implying 15% upside from Thursday's close. Raymond James also downgraded Southwest shares to outperform from strong buy, calling it a "Texas-size heartache." The firm reduced its price target to $40 from $47, implying a 21.1% rally. Bank of America decreased its price target on shares to $35 from $45, which implies just 6% upside from where shares ended Thursday. Southwest shares shed 0.6% Friday before the bell, following an almost 9% tumble during the previous trading session.
Persons: Michael Linenberg, Linenberg, Raymond James, Savanthi Syth, Syth, Andrew Didora, Didora, — CNBC's Michael Bloom Organizations: Southwest Airlines, Deutsche Bank, Deutsche, Southwest, Bank of America Locations: Alaska, American, United, Southwest, Texas
July 20 (Reuters) - Alabama's Republican-controlled legislature on Friday passed a new congressional map that increased the number of Black voters in one of the state's districts, but Democrats said the plan defied a U.S. Supreme Court ruling intended to protect minority voters' rights. More than one-quarter of Alabama's residents are Black, but under a Republican-drawn map approved in 2021, only one of the state's seven congressional districts, the 7th, is majority Black. Senator Bobby Singleton, a Black Democrat, accused fellow lawmakers of playing a "game" with Black voters. But Republicans said they were confident the 2nd district's new lines provided a meaningful opportunity for Black voters. Last week, a New York state appeals court ordered lawmakers to redraw the state's congressional map.
Persons: Scott Douglas, Terri Sewell, Bobby Singleton, Singleton, Michael Li, New York University's, Josephine Walker, Joseph Ax, Scott Malone, Aurora Ellis Organizations: Republican, U.S, Supreme, Greater Birmingham Ministries, Democratic U.S, Republicans, U.S . House, Representatives, Black, New York, Center for Justice, Democratic, Thomson Locations: Alabama, Black, U.S, New, New York, Washington
The plaintiffs in the Supreme Court case have already vowed to challenge either map in court, saying both would still violate the law. In 2022, a three-judge panel in a federal district court invalidated the current map as unlawful. Black Democratic lawmakers have called the maps a slap in the face to Black voters - and to the courts. "It is an embarrassment," said Juandalynn Givan, a Jefferson County legislator, adding that the Republican plan amounted to dropping "an F-bomb on the United States Supreme Court." "There certainly are places in the country where a 42% Black district would elect a Black-preferred candidate," Li said.
Persons: Scott Douglas, Terri Sewell, Juandalynn Givan, Michael Li, New York University's, Li, Joseph Ax, Josephine Walker, Scott Malone, Aurora Ellis Organizations: Republican, U.S, Supreme, Republicans, U.S . House, Senate, Greater Birmingham Ministries, Democratic U.S ., Lawmakers, Black Democratic, United States Supreme, New York, Center for Justice, Black, Democratic, Thomson Locations: U.S, Alabama's, Alabama, Black, Jefferson County, New, New York
Baron Opportunity Fund has soared 45% this year, blowing its tech peers out of the water. The opportunity fund (BIOPX), with $1 billion assets under management, has notched a 10-year total return of about 15% on an annualized basis, according to Morningstar. Lippert said he owns about 40 names in the portfolio, including this year's big AI winner Nvidia . Another megacap name that Lippert owns to capitalize on the AI boom is Microsoft . "Everyone wants to talk about the big names, but we play this in a portfolio way," Lippert said.
Persons: Opportunity, Michael Lippert, we're, Lippert, Morningstar Organizations: Nvidia, Microsoft, AMD, Marvell Locations: ChatGPT
It'll be the company's first major new product since the first Apple Watch in 2014. Apple's goggles are expected be sleekly designed and capable of toggling between totally virtual or augmented options, a blend sometimes known as "mixed reality." Magic LeapDaniel Diez, Magic Leap's chief transformation officer, said there are four major questions Apple's goggles will have to answer: "What can people do with it? The anticipation that Apple's goggles are going to sell for several thousand dollars already has dampened expectations for the product. But those forecasts were obviously made before it's known whether Apple might be releasing a product that alters the landscape.
Persons: It'll, Apple, Steve Jobs, hasn't, Mark Zuckerberg, Tim Cook, Cook, it's, Sergey Brin, Daniel Diez, Magic, Dan Ives, Zuckerberg, Leap's Diez Organizations: Apple, Apple Watch, Meta, Google, Microsoft, Wedbush Securities, CCS Insight Locations: Cupertino , California, Italy, San Francisco
It was one the president deployed once again behind closed doors at the White House. With Memorial Day on the horizon, senior White House officials said protecting veterans’ benefits was a top priority. They also knew it was a sensitive issue for Republicans’ politically, especially as House Republicans parried White House allegations about cuts to veterans’ services. White House officials would engage in conversations where their Republican counterparts would outline a potential resolution on issues. For months, White House officials hoped – and to some degree based on past battles, expected – Senate Republican Leader Mitch McConnell would engage in finding a resolution.
Persons: Joe Biden, Biden, , ” Biden, Kevin McCarthy, simmered, Steve Ricchetti, Louisa Terrell, Shalanda Young, reticence, Biden didn’t, McCarthy, ’ carveouts, Republicans ’, Republicans parried, ” Terrell, , ” Young, Jeff Zients, , would’ve, that’s, ” Zients, ” Ricchetti, Patrick McHenry, Young, Michael Linden, Ricchetti, McCarthy’s, Mitch McConnell, Terrell, McHenry, Garret Graves, Graves, Dan Meyer, they’ve, “ There’s, you’re, cleaver Organizations: CNN, Resolute, Legislative, White, Republican, FBI, Republicans, Internal Revenue Service, SNAP, Congressional, Office, Progressive, Young, White House, GOP, Biden, Republican Rep, Congress, dropoff, Air Force Academy Locations: Washington, Garret Graves of Louisiana, McHenry, Louisiana, Ukraine, Colorado
Biden’s Debt Deal Strategy: Win in the Fine Print
  + stars: | 2023-06-03 | by ( Jim Tankersley | ) www.nytimes.com   time to read: +2 min
Mr. Biden had insisted for months that he would not negotiate over raising the borrowing limit. But privately, many aides had been planning on talks all along — though they refused to admit those talks were linked to the debt limit. The Biden team reasoned that it would have to negotiate fiscal issues this year anyway, both on appropriations bills and on programs like food stamps that are included in a regularly reauthorized farm bill. It featured work requirements and measures to speed fossil fuel projects, and it raised the debt limit for one year. Mr. Biden, under fire from business groups and others who feared the standoff could result in the United States running out of money before the debt limit was raised, soon agreed to designate a team of negotiators.
Persons: Biden, Lael Brainard, Janet L, McCarthy, Young, Michael Linden, Louisa Terrell, Ricchetti Organizations: Biden, National Economic Council, Social Security, White House Locations: United States
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