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☆ Exercise reduces stressful brain activity, which can lead to less heart disease risk, study shows
▼ + stars: | 2024-04-15 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +5 min

In addition to the physical benefits of exercise, it’s also associated with a reduction in stress signals in the brain, which leads to a decreased risk of cardiovascular disease, according to the study. For people without any history of depression, the benefit of exercise on cardiovascular disease reduction plateaued after about 300 minutes of moderate physical activity a week. How it worksExercise reduced stress signals and increased prefrontal cortical signals, Tawakol said. In part, exercise appeared to reduce heart disease risks by reducing the stress signals, Tawakol said. But figure out a way to get a physical activity in that you truly enjoy,” he said.

Persons: it’s, Brigham Biobank, ”, Ahmed Tawakol, “, Andrew Freeman, Freeman, Tawakol, ” Tawakol, wasn't, Oleg Breslavtsev, Karmel Choi, ” Freeman Organizations: CNN’s, CNN, Mass, American College of Cardiology, Mass General Hospital, Harvard Medical School, Jewish Health, Getty, Massachusetts General Hospital Locations: Boston, Denver, Massachusetts

☆ I've studied brain foods for 20+ years—here are 5 of my favorite breakfasts for focus, energy and mental health
▼ + stars: | 2024-04-10 | by ( Dr. Uma Naidoo | ) www.cnbc.com time to read: +1 min

Breakfast provides the brain with its first source of energy every morning. Fueling the brain is key for focus, clarity, and optimal functioning throughout the day. They also contribute to the neuroinflammation (inflammation around the brain) that's associated with brain fog and poor concentration. After that, here are five of my favorite breakfast brain foods. They're rich in key nutrients and functional compounds that promote better energy, clarity, and mental health.

Organizations: Psychiatry, Massachusetts General Hospital Locations: U.S, Massachusetts

CNN —Rick Slayman, the world’s first living recipient of a genetically edited pig kidney transplant, was discharged from the hospital Wednesday, two weeks after his operation, Massachusetts General Hospital said in a statement. “He is recovering well and will continue to recuperate at home with his family,” the hospital said on X, formerly Twitter. Rick Slayman in his hospital room at Massachusetts General Hospital before his discharge on Wednesday April 3, 2024. Michelle Rose/Massachusetts General HospitalHis surgery is the third such xenotransplant of a pig organ into a living human. The first two transplants were hearts transplanted into living patients that had run out of other transplant options.

Persons: Rick Slayman, Slayman, I’ve, ”, Michelle Rose, Dr, Sanjay Gupta, ” Slayman Organizations: CNN, Massachusetts General Hospital, Massachusetts Department of Transportation, CNN Health, Procurement, Transplantation Network Locations: Massachusetts, U.S

☆ Patient With Transplanted Pig Kidney Leaves Hospital for Home
▼ + stars: | 2024-04-03 | by ( Roni Caryn Rabin | ) www.nytimes.com time to read: 1 min

The first patient to receive a kidney transplanted from a genetically modified pig has fared so well that he was discharged from the hospital on Wednesday, just two weeks after the groundbreaking surgery. The transplant and its encouraging outcome represent a remarkable moment in medicine, scientists say, possibly heralding an era of cross-species organ transplantation. Two previous organ transplants from genetically modified pigs failed. In one patient, there were signs that the immune system had rejected the organ, a constant risk. But the kidney transplanted into Richard Slayman, 62, is producing urine, removing waste products from the blood, balancing the body’s fluids and carrying out other key functions, according to his doctors at Massachusetts General Hospital.

Persons: Richard Slayman Organizations: Massachusetts General Hospital Locations: Massachusetts

☆ Deep brain stimulation didn’t work for a young OCD patient until new brain maps changed everything
▼ + stars: | 2024-03-15 | by ( Brenda Goodman | ) edition.cnn.com time to read: +7 min

After treatment with targeted deep brain stimulation, she hopes to walk out soon and, for the first time in her adult life, live independently, in her own apartment. Doctors used a tube that led into her stomach through her nose to give her food and gave her fluids intravenously. Deep brain stimulation for severe obsessive-compulsive disorder helped Julia Hum earn her high-school equivalency certificate last year. Refining deep brain stimulationHum had a deep brain stimulator implanted in 2021. Deep brain stimulation can be life-changing, but it doesn’t work equally well for everyone, and researchers say they’re getting closer to understanding why.

Persons: Julia Hum, Hum, “, Doctors, it’s, ” Hum, Andreas Horn, “ I’ll, I’ll, Darin Dougherty, didn’t, they’re, ” Horn, Sameer Sheth, ”, Sheth, Dougherty, “ It’s, she’s, Dr, Sanjay Gupta, “ Hope Organizations: CNN, General Hospital, Doctors, Mass General Research Institute, Baylor College of Medicine, CNN Health Locations: Massachusetts, Houston

☆ Inside Startupland's 'Shroom Boom'
▼ + stars: | 2024-03-13 | by ( Samantha Stokes | ) www.businessinsider.com time to read: +11 min

This story is available exclusively to Business Insider subscribers. Frohman is part of a small but growing community within the startups industry that is experimenting with small doses of psilocybin to improve focus and productivity. Business Insider spoke with multiple founders and investors who microdosed, but wished to be anonymous. The person declined to share their name for publication, but their identity is known by Business Insider. Vancouver-based Filament Health is working to expand access to natural psychedelics through an extraction and drug-discovery process, while brick-and-mortar shops Shroomyz and Fun Guyz are further fueling the Canadian "'Shroom Boom".

Persons: Scott Frohman, Frohman, hasn't, Microdosing, James Fadiman —, Koel Robinson, Robinson, Richard Laver, Steve Jobs, Peter Grinspon, Grinspon, Peggy Van de Plassche, Van de Plassche, She's, Justin Zhu, I'm, microdosing, they're, It's Organizations: Business, Rocket Beverage Group, Erewhon, Foods, Massachusetts General Hospital, Harvard Medical School, BMO, PsyMed Ventures, Noetic Fund Locations: Florida, San Francisco, Denver, Minneapolis, In Oregon, California , Iowa, Washington State, Vermont, Massachusetts, Vancouver, Palo Santo

☆ Living drugs that reprogram patients’ immune cells show early promise against hard-to-treat brain tumors
▼ + stars: | 2024-03-13 | by ( Brenda Goodman | ) edition.cnn.com time to read: +10 min

Only 3% to 5% of people who are diagnosed with this type of brain tumor will be alive three years later. Now, an experimental therapy that reprograms a person’s own immune cells to attack these tumors is showing some exciting promise. Doctors first harvested immune fighters called T-cells from his blood and then genetically modified them in a lab so they’d recognize and bind to specific proteins on the surface of the brain tumor cells. After a single 10-milliliter infusion of about 10 million CAR-T cells, Fraser’s tumor began to shrink. Three-quarters of the participants had had their brain tumors come back at least twice.

Persons: ”, Otis Brawley, –, they’ll, ” Brawley, Tom Fraser, Brigham, Debbie Fraser, Fraser, He’s, Marcela Maus, ” Fraser, Maus, “, ” Maus, Christine Brown, ’ Brown, ” Brown, hasn’t, Brown, Dr, Donald O’Rourke, “ They’re, O’Rourke, ” O’Rourke, Sanjay Gupta, you’re, they’re, it’s Organizations: CNN, Johns Hopkins University, American Cancer Society, City of Hope Cancer Center, University of Pennsylvania, Massachusetts General, Mass, New England, of Medicine, Doctors, Mass General Cancer Center, Tv3, Cell Therapeutics Research, of, Nature, Penn, Excellence, University of Pennsylvania Perlman School of Medicine, CNN Health Locations: City, Duarte , California, Massachusetts, Rochester , New York, Boston, of Hope, Hope

☆ Any use of marijuana linked to higher risk of heart attack and stroke, study says
▼ + stars: | 2024-02-28 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +5 min

CNN —Smoking, vaping or eating marijuana is linked to a significantly higher risk of heart attack and stroke, even if a person had no existing heart conditions and did not smoke or vape tobacco, a new study found. While both daily and non-daily users had an increased risk of heart attack and stroke compared to nonusers, stroke risk rose 42% and the risk of heart attack rose 25% if cannabis was used daily, the study found. Younger adults — defined as men under 55 and women under 65 years old — who used marijuana had a 36% higher risk of coronary heart disease, heart attack and stroke regardless of whether they also used traditional tobacco products. Heart disease and marijuana use a known linkPrevious research has already found a link between heart disease and marijuana use. Also called atherosclerosis, CAD is the most common type of heart disease, according to the CDC.

Persons: ”, Abra Jeffers, ” Jeffers, Robert Page II, ” Page, Page, — Organizations: CNN, Massachusetts General Hospital, University of Colorado Skaggs School of Pharmacy, Pharmaceutical Sciences, American Lung Association, Getty, American Heart Association, US Centers for Disease Control, Prevention, CDC Locations: Boston, Aurora , Colorado

☆ Antidepressant prescriptions to youths spiked during pandemic, study finds
▼ + stars: | 2024-02-26 | by ( Kristen Rogers | ) edition.cnn.com time to read: +7 min

CNN —Many young people have reported having poor mental health during and after the Covid-19 pandemic. Their experiences are affirmed by a new study finding that the rate of prescribing antidepressants to this group also spiked during the same period. But since the Covid-19 outbreak in the United States in March 2020, the dispensing rate rose nearly 64% faster than normal, according to the study published Monday in the journal Pediatrics. In female adolescents ages 12 to 17, the dispensing rate increased 130% faster after March 2020, Chua said. “I can’t tell you how many pediatricians have told me that they feel like they’re just mental health clinicians at this point,” he said.

Persons: . Kao, Ping Chua, Chua, ” Chua, ”, “, Neha Chaudhary, wasn’t, ” Chaudhary, don’t, Chaudhary, “ Young Organizations: CNN, Pediatrics, University of Michigan’s School of Public Health, Massachusetts General Hospital, Modern Health, Food and Drug Administration Locations: United States, Massachusetts, “

☆ How to fight dementia, according to neurologists
▼ + stars: | 2024-02-12 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +17 min

What about diabetes, cancer, thyroid disease, high blood pressure or heart disease? Some of the questions might seem unexpected to those who don’t write about brain health. However, my risk of developing vascular dementia, the second most common type after Alzheimer’s disease, is elevated. "Such spikes cause brain inflammation, disrupt brain metabolism and increase shrinkage of the thinking part of the brain," Isaacson said. The National Institute on Aging currently supports nearly 500 active clinical trials on Alzheimer’s disease and related dementias.

Persons: Louise Dittner, Krysta, Ryan LaMotte, It’s, ”, Natalia Rost, “, Rost, ” Rost, Richard Isaacson, ” Isaacson, mockingbird …, birthed, it’s, I’ve, Isaacson, Sandee LaMotte Organizations: CNN, Comprehensive, Massachusetts General Hospital, Harvard Medical School, American Academy of Neurology, Boca Raton, Weill Cornell Medicine, Presbyterian, Mayo Clinic, Volunteers, Alzheimer’s, National Institute on Aging, National Institutes of Health Locations: Massachusetts, Boston, neonatologists, Florida, United, New York, New York City, Nature

☆ Mammography AI can cost patients extra. Is it worth it?
▼ + stars: | 2024-01-26 | by ( Michelle Andrews | Kff Health News | ) edition.cnn.com time to read: +8 min

In recent years, AI software that helps radiologists detect problems or diagnose cancer using mammography has been moving into clinical use. This extra review has enormous potential to improve the detection of suspicious breast masses and lead to earlier diagnoses of breast cancer. With RadNet’s AI tool, “it’s as if all patients get the benefit of our very top performer.”But is the tech analysis worth the extra cost to patients? The health system has developed AI models and is testing the technology with mammograms but doesn’t yet offer it to patients, she said. In the late 1980s and early 1990s, “computer-assisted detection” software promised to improve breast cancer detection.

Persons: “, ”, Etta Pisano, RadNet, Gregory Sorensen, Sorensen, generalists, ” Sorensen, Laura Heacock, NYU Langone Health’s, Heacock, it’s, Constance Lehman, ” Lehman, RadNet’s, Dr, Sanjay Gupta, Christoph Lee, mammography, Robert Smith, ” Smith, Smith, we’re Organizations: Health, American College of Radiology, NYU, Cancer, “, National Cancer Institute, FDA, Medicare, Services, CMS, Radiology, Massachusetts General Hospital, Harvard Medical School, Imaging Research, Mass, Get CNN, CNN Health, Screening, Research, University of Washington School of Medicine, American Cancer Society, Kaiser Health, KFF Locations: Manhattan, Baltimore, RadNet, New York, New Jersey, mammograms, Boston, Massachusetts, United States, Europe, Sweden, U.S

☆ 4 ways to move past seasonal sadness with physical activity
▼ + stars: | 2024-01-20 | by ( Dana Santas | ) edition.cnn.com time to read: +6 min

For some, the seasonal shift can lead to a clinically depressive state aptly called seasonal affective disorder, or SAD. Even better, it takes less effort than you might think to realize the mental benefits. Below, I’ve outlined four science-backed ways you can become more active to boost your mental health and ease the winter blues. Meeting the World Health Organization’s guidelines of 2.5 hours of moderate exercise weekly provides maximum overall physical and mental health benefits, but studies have shown that even relatively small doses of activity offer significant mental health benefits. Whatever form of exercise you choose, adding just a little more physical activity into your life will provide noticeable mood-boosting benefits to help you get past the seasonal slump.

Persons: Dana Santas, I’ve, Julia Amaral, What’s Organizations: Pain, CNN, American Psychological Association, Getty, Facebook, Massachusetts General Hospital, CNN’s Locations: playtime

☆ Daily Multivitamin Might Help Aging Brains
▼ + stars: | 2024-01-18 | by ( Jan. | At P.M. | ) www.usnews.com time to read: +5 min

By Dennis Thompson HealthDay Reporter(HealthDay)THURSDAY, Jan. 18, 2024 (HealthDay News) -- A daily multivitamin could help people keep their brains healthy as they age, a new trial finds. Results suggest taking multivitamins could help prevent memory loss and slow cognitive aging among older adults, researchers report in the Jan. 18 issue of the American Journal of Clinical Nutrition. The effect was measurable: A daily multivitamin slowed brain aging by the equivalent of two years compared to placebo. “Cognitive decline is among the top health concerns for most older adults, and a daily supplement of multivitamins has the potential as an appealing and accessible approach to slow cognitive aging,” he said. It looked at whether a special cocoa extract supplement, a daily multivitamin (in this case Centrum Silver) or both might help boost health.

Persons: Dennis Thompson, Dr, Richard Caselli, “, Chirag, ”, ” Yvas, Olivia Okereke, Preventive Medicine Howard Sesso, Zaldy Tan, ” Tan, Caselli, Sesso, Brigham Organizations: American, Clinical Nutrition, Mayo Clinic, NBC News, Chirag Vyas, Massachusetts General Hospital’s Department of Psychiatry, Cocoa, Massachusetts General Hospital, MGH, Brigham, Women’s Hospital, Columbia University, Wake Forest University, National Institutes of Health, Mars Inc, Pfizer, COSMOS, Women’s, Preventive Medicine, Council for Responsible Nutrition, Cleveland Clinic, NBC Locations: Arizona, Massachusetts, multivitamins, Jona, Los Angeles

☆ What weight tells us about our health
▼ + stars: | 2024-01-17 | by ( Dr. Sanjay Gupta | ) edition.cnn.com time to read: +12 min

(CNN) — If you’ve been paying attention to health news recently, you may have noticed a subtle but real shift in the way society discusses body weight. Beyond health care dollarsDespite changing attitudes about larger bodies, excess weight does carry a price. From a health care standpoint, it costs the country a lot of money. According to a study published in the journal The Lancet in 2020, 27% of total health care expenditures in 2016 — about $730.4 billion — could be attributed to “modifiable risk factors” for preventable health conditions like cardiovascular disease. That was eight years ago, when our total health care expenditure was $2.7 trillion, according to the study.

Persons: you’ve, We’re, Dr, Fatima Cody Stanford, “, They’re, Adolphe Quetelet, Ancel Keys, ”, ” Stanford, Morgan, That’s, we’ll, Daniel Lieberman, who’ll, Oprah Organizations: CNN, American Medical Association, Massachusetts General Hospital, Harvard Medical School, National, bloodwork, Harvard Locations: Belgian

☆ The CEO of an A16z-backed healthcare startup is pitching a better way to save money on obesity care
▼ + stars: | 2023-12-29 | by ( ) www.businessinsider.com time to read: +8 min

Boyarsky Pratt said about 35% of Knownwell's patients come for primary care, while the rest see the company's providers for their metabolic health. They can prescribe GLP-1 drugs, but they're just one tool the company uses to treat obesity, Boyarsky Pratt said. It's also planning to partner with more health systems to help them expand access to weight care. It partners with one large system in Massachusetts now, but Boyarsky Pratt declined to disclose which one. "The data shows that the earlier patients get into a comprehensive treatment, the better for the long-term course of the disease," Boyarsky Pratt said.

Persons: —, Brooke Boyarsky Pratt, Andreessen Horowitz, Boyarsky Pratt, Knownwell, Angela Fitch, Berkadia, Fitch, Needham, Boyarsky Platt, they'd, Michael Siluk, It's Organizations: Service, Business, GLP, BMI, Medicare, Obesity Medicine Association . Obesity Medicine, University of Pennsylvania, Harvard Business School, Berkshire Hathaway, Obesity Medicine Association, Weight, Flare Capital Partners, Staff, Getty, American Academy of Pediatrics Locations: Boston, GLP, Massachusetts, Knownwell, Needham , Massachusetts, telehealth

The poll found that 55% of Black respondents said they feel like they must be very careful about their appearance to be treated fairly at medical visits. That’s similar to the rate for Hispanic and Alaska Native patients – and nearly double the rate for white patients. Nearly 30% of Black respondents prepare to be insulted, also about double the rate for white patients. Asians and Hispanics were three times more likely to say they’ve been treated badly in a health care setting because of their race than white respondents and Black respondents were 6 times more likely. “The consequences in health care are really striking and very frightening, honestly, to understand what people need to do to be taken seriously, to be seen as a whole person,” she said.

Persons: KFF, Christine Wright, Wright, she’s, “, you’re, ”, Drew Altman, Allison Bryant, Bryant, ” Bryant, Luna Roldán, te, they’ve, Mary Conlon, Robert Wood Johnson Organizations: Associated Press, Massachusetts General Hospital, Latina, Indians, Alaska Natives, Associated Press Health, Science Department, Robert Wood Johnson Foundation, AP Locations: Alaska, U.S, Massachusetts, Lake Worth , Florida

☆ Address 12 health factors to prevent brain disease, research suggests
▼ + stars: | 2023-12-05 | by ( Kristen Rogers | ) edition.cnn.com time to read: +6 min

The 21-point Brain Care Score refers to how a person fares on 12 health-related factors concerning physical, lifestyle and social-emotional components of health, according to the study published December 1 in the journal Frontiers in Neurology. Those in their 50s had a 32% lower risk of dementia and a 52% lower chance of stroke. Participants older than 59 had the lowest estimates, with an 8% lower risk of dementia and a 33% lower risk of stroke. But in terms of explaining the overall findings, many past studies have affirmed the benefits of these health components for brain health. “But as scientists, we always want to see proof.”Participating in studies like this one can be a good way to manage your brain health, Isaacson said — especially if you have limited access to health care.

Persons: ”, Jonathan Rosand, Kistler, “, Richard Isaacson, Isaacson wasn’t, ” Isaacson, it’s, ‘, Isaacson, ” Rosand, — Organizations: CNN, BCS, McCance, Brain Health, Massachusetts General Hospital, Harvard Medical School, National Institutes of Health Locations: Massachusetts, United States, United Kingdom, Florida

☆ Maker of Wegovy, Ozempic showers money on U.S. obesity doctors
▼ + stars: | 2023-12-01 | by ( ) www.reuters.com time to read: +23 min

Novo spent at least $25.8 million over the past decade on U.S. medical professionals to promote its two obesity drugs, Wegovy and Saxenda, the analysis found. Jastreboff has also worked on clinical trials of obesity drugs for Eli Lilly, which markets a Wegovy competitor. Some doctors said Novo’s payments exemplify how the flood of industry money can dominate decision-making about care and coverage. Government pharmacy officer Solaru said her agency concluded that the new obesity drugs could be cost-effective by preventing other weight-related diseases and boosting workplace productivity. In January, the personnel office told its health plans they must cover at least one GLP-1 obesity drug for 8 million workers, retirees and family members.

Persons: Lee Kaplan, Kaplan, ”, gastroenterologist, He’s, Novo, Donna Ryan, Ryan, “, ” Kaplan, ” Novo, Robert Lustig, “ I’m, Lustig, They’re, Ania, ” Jastreboff, Jastreboff, Eli Lilly, Lilly’s Zepbound, Lilly, ” Lilly, Novo’s, Ayana, Sanders, Arthur Kellermann, ” Kellermann, mouthpieces, ’ ”, “ I'm, Jamy Ard, Ard, Dele, ” Solaru, ” Ryan, Scott Kahan, Kahan, Solaru, Christine Gallagher, Wegovy, Rebekah Carl, Carl, Jen Wexler, gaunt, Wexler Organizations: Novo Nordisk, Dartmouth, Nutrition Institute, Massachusetts General Hospital, Harvard Medical School, Reuters, Cambridge, Obesity Society, U.S ., Management, Reuters . Pharmaceutical, ”, U.S, United, National Health Service, University of California, U.S . Food, Drug Administration, Doctors, Wegovy’s, BMI, Yale University’s Center, Weight Management, Wall Street, American Medical Association, Rutgers University’s School of Public Health, Affordable, . Pharmaceutical, Companies, Uniformed Services University of Health Sciences, Wake Forest University, Wake Forest Baptist Health Weight Management, Obesity, Pennington Biomedical Research, U.S . National Institutes of Health, Personnel Management, Coalition, STOP, George Washington University, Novo Locations: CAMBRIDGE, Massachusetts, Boston, U.S, Novo, Danish, United States, Louisiana, San Francisco, Wegovy, Pennington, Baton Rouge , Louisiana, Government, New Columbia , Pennsylvania, Florida

☆ Innovative Cancer Treatment May Sometimes Cause Cancer, F.D.A. Says
▼ + stars: | 2023-11-28 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com time to read: +3 min

Cancer specialists said the treatments have saved the lives of thousands of patients with blood cancers. And, he said, “I haven’t seen a single one” develop a new T cell cancer. When patients’ T cells are engineered to make proteins that attack cancer cells, a virus helps slip new genes into T cell DNA. Even without chemotherapy or radiation, Dr. Maus added, patients with blood cell cancers are especially susceptible to developing other blood cell cancers. But Dr. DiPersio said, “it is more of a smoking gun.”The F.D.A.

Persons: Marcela V, Maus, John DiPersio, Louis, “, ”, DiPersio, —, . Maus Organizations: Massachusetts General Hospital, Washington University School of Medicine Locations: Massachusetts, St

☆ Shopping feels like an addiction around the holidays for a reason. Experts explain why
▼ + stars: | 2023-11-24 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +7 min

Between the decorations, feasts and gift-giving, the winter holidays give us plenty of reasons to spend money, which human brains find rewarding. Why our brains like shoppingIt’s no surprise that shopping feels good — it feeds our brains’ rewards systems. On top of that, many people are paid lots of money to make shopping feel even more rewarding, Duhaime said. Internet shoppingThe sacrifices needed to buy holiday gifts and goods drastically decrease when you go online, Duhaime said. Less shopping, more holiday cheerAs much as we want to give our families the best holidays ever every year, more shopping doesn’t always bring us closer to that goal, Duhaime said.

Persons: you’ll, ”, Ashish Bhatt, Bhatt, “, Ann, Christine Duhaime, Duhaime, Alexandra Cromer, Cromer Organizations: CNN, Addiction Center, Disorders, Harvard Medical School, Massachusetts General Hospital, Mental Health Services, “ Retailers Locations: Massachusetts, Boston, Richmond , Virginia

COVID-19 vaccine uptake this fall is perhaps not what many had hoped it would be. The rates appear to be on track with the rollout of the previous updated COVID-19 shot but fall significantly short of the flu vaccine coverage so far this season. A couple other factors have probably affected vaccine uptake to a smaller extent. Smith says that it is surprising how the COVID-19 vaccination rates compare to flu shot uptake. Combination flu and COVID-19 vaccines are in the works but aren’t expected to be available to the public until 2025.

Persons: “ It's, ”, Camille Kotton, ” Kotton, “, they've, haven’t, they're, Kotton, didn't, Emily Smith, Smith, it's, it’s Organizations: Massachusetts General Hospital, Centers for Disease Control, CDC, George Washington University Milken Institute School of Public Health, U.S . Locations: Massachusetts, COVID, U.S

☆ V.A. Recruits Millionth Veteran for Its Genetic Research Database
▼ + stars: | 2023-11-15 | by ( Gina Kolata | More About Gina Kolata | ) www.nytimes.com time to read: +3 min

says its database offers a more diverse population: 175,000 people with African ancestry and 80,000 Hispanics joined the Million Veteran Program. For example, said Dr. Sumitra Muralidhar, director of the Million Veteran Program, researchers found genes linked to having flashbacks of traumatic events, a feature of post-traumatic stress. Although researchers can examine genetic and other data and links to medical records, fewer than 10 people at the V.A. Those records, Dr. Muralidhar said, are held at a facility in Boston that is “heavily secured.”What It Looks Like: Veterans hope the database will help. hospital told Octavia Harris, 60, of San Antonio, about the Million Veteran Program.

Persons: ”, Shereef Elnahal, “, Amit V, Sumitra Muralidhar, Muralidhar, Octavia Harris, Harris Organizations: Employees, Department sVeterans Affairs, Million, Massachusetts General Hospital, Million Veteran, Navy Locations: Europe, Massachusetts, Boston, San Antonio

A new version of the popular diabetes treatment Mounjaro can be sold as a weight-loss drug, U.S. regulators announced Wednesday. The U.S. Food and Drug Administration approved Eli Lilly's drug, named Zepbound. Zepbound is the latest diabetes drug approved for chronic weight management, joining Novo Nordisk's Wegovy, a high-dose version of its diabetes treatment Ozempic. Those with diabetes, who have a harder time losing weight, cut about 12%, or nearly 27 pounds (12 kilograms), the FDA said. Approved for weight loss in 2021, Wegovy helped people lose about 15% of their weight or 34 pounds (15 kilograms), according to study results.

Persons: Eli Lilly's, dieters, Zepbound, Wegovy, Fatima Cody Stanford, tirzepatide, pare, ”, Katherine Saunders, Eli Lilly, Mounjaro, Kelly Burns, Burns Organizations: U.S . Food, Drug Administration, Novo Nordisk's Wegovy, FDA, Massachusetts General Hospital, New York's Weill Cornell Medicine, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: U.S, Zepbound, Wegovy, Massachusetts, Boston, St . Petersburg , Florida

☆ Why it can be so hard to stay sober
▼ + stars: | 2023-11-02 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +8 min

To understand why the problem is so widespread, people must recognize the complexities around not just getting sober — but staying sober, Kelly said. Those predispositions can combine with a history of trauma or developmental experiences to make someone much more likely to develop an addiction, Kelly added. For some people, mental illnesses such as depression or anxiety occur alongside but independent of their addiction, Kelly said. “It does not mean that this individual is never going to be able to achieve recovery,” Dick said. “The devious nature of drugs means that when an individual has been using heavily, it also changes their brain and that makes it harder to maintain recovery,” Dick said.

Persons: Matthew Perry, “, “ I’ve, ” Perry, ‘ Will, ’ ”, Danielle Dick, Dr, John F, Kelly, ”, ‘, ’, ” Dick, Dick, ” Kelly, —, they’ve, Dick said, you’ve, Don’t, Nancy Diazgranados, relapses, ” Diazgranados, Matt Organizations: CNN, Hollywood, Rutgers Addiction Research, Harvard Medical, Hospital Recovery Research, US Centers for Disease Control, Addiction, CDC, National Institute on Drug, National Institute, Alcohol Locations: Piscataway , New Jersey, Massachusetts, United States

☆ Loss of slow-wave sleep raises dementia risk, study finds
▼ + stars: | 2023-10-30 | by ( Kristen Rogers | ) edition.cnn.com time to read: +6 min

CNN —Loss of slow-wave sleep as you age may increase your risk of developing dementia, according to a new study. Slow-wave sleep is the third stage of sleep, which is important for brain health. Each percentage decrease in slow-wave sleep per year was linked with a 27% increased risk of developing dementia and a 32% higher risk of Alzheimer’s disease dementia. The rate of slow-wave sleep loss accelerated from age 60, peaked from ages 75 to 80 and slowed afterward. “This is an important study yet again showing the impact of quality of sleep on a person’s risk of cognitive decline and dementia,” Isaacson said.

Persons: ”, Matthew P, Pase, “, Richard Isaacson, Isaacson wasn’t, ” Pase, ” Isaacson, it’s, Rudolph Tanzi, Tanzi wasn’t, Pase’s Organizations: CNN, Monash University, Framingham Heart Study, US, Blood Institute, Study, Genetics, Aging Research, Massachusetts General Hospital, ” Locations: Australia, Florida, Framingham, Massachusetts

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