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☆ Tackle these 14 factors to lower dementia risk, report suggests
▼ + stars: | 2024-07-31 | by ( Kristen Rogers | ) edition.cnn.com time to read: +8 min

But addressing 14 risk factors over the course of one’s life — starting in childhood — could prevent or delay nearly half of cases, according to a large report by 27 dementia experts. “The progress in preventing and treating dementia is accelerating.”The initial 12 risk factors were linked with 40% of cases, but the new report suggests addressing the 14 risk factors could help eliminate or delay 45% of dementia cases, said Livingston, a professor of psychiatry of older people at University College London. This “critical” update calls attention to two risk factors that preventive neurologist Dr. Richard Issacson says his clinical practice has been evaluating for over a decade. Influencing brain functionThe report doesn’t establish with certainly that these risk factors directly cause dementia, experts said. But other research has provided theories on the link between these vulnerabilities and dementia risk.

Persons: CNN —, ”, Dr, Gill Livingston, Livingston, Richard Issacson, Isaacson, wasn’t, It’s, Klaus Ebmeier, Ebmeier wasn’t, ” Livingston, Glen R, Finney, Alzheimer’s, Susan Kohlhaas, Kohlhaas, …, ” Finney Organizations: CNN, Lancet, University College London, University of Oxford, American Academy of Neurology, Alzheimer’s Research Locations: midlife, Florida, Wilkes Barre , Pennsylvania, €

☆ Commonly used drug may extend women’s fertility, claim researchers – here’s what you need to know about rapamycin
▼ + stars: | 2024-07-31 | by ( Stephane Berneau | University Of Central Lancashire | ) edition.cnn.com time to read: +7 min

This early-established ovarian reserve can affect a person’s ability to become pregnant throughout their reproductive years. As a woman ages, her ovarian reserve diminishes until she has only a limited number of good-quality follicles remaining. The average age of menopause is 51 years – though this can vary broadly between women depending on their ovarian reserve. The ovarian reserve was monitored by transvaginal ultrasound and several blood tests to detect various ovarian hormones. But if the clinical trial shows rapamycin is beneficial, this could help women with low ovarian reserve and those hoping to prolong their fertility.

Persons: it’s, It’s, rapamycin, We’re, Stéphane Berneau Organizations: CNN, Research, University of Central, Society, Biochemical Society, Alzheimer’s Research, Anatomical Society Locations: University of Central Lancashire

☆ Ozempic predecessor suggests potential for GLP-1 drugs in Alzheimer’s in early trial
▼ + stars: | 2024-07-30 | by ( Meg Tirrell | ) edition.cnn.com time to read: +7 min

“This is the first study that actually looked at a relatively large number of patients for whether there is any neuroprotective effect in Alzheimer’s disease,” Edison said. The trial enrolled predominantly people with mild Alzheimer’s disease, measured by a test known as the Mini-Mental State Examination, a scale that goes up to 30. The GLP-1 drug class also includes Eli Lilly’s Mounjaro and Zepbound, which use the active ingredient tirzepatide, which mimics not just the hormone GLP-1 but another called GIP. But it hasn’t announced any trials of its GLP-1 drugs in Alzheimer’s. GLP-1 drugs can have side effects, though, primarily gastrointestinal problems like nausea and vomiting.

Persons: liraglutide, “, ”, Maria Carrillo, Carrillo, Paul Edison, ” Edison, Edison, Eli Lilly’s Mounjaro, Alzheimer’s Lilly, hasn’t, Lilly, Lars Fruergaard Jorgensen, there’s, Dr, Sanjay Gupta, semaglutide Organizations: CNN, Alzheimer’s Association International Conference, Alzheimer’s Association, Novo Nordisk, Imperial College London, ”, Nordisk, ” Novo Nordisk, CNN Health, University of Oxford, Alzheimer’s Society, Alzheimer’s Locations: United Kingdom, Philadelphia, Alzheimer’s, ” Novo, Danish

☆ Shingles vaccines may reduce dementia risk, two large new studies suggest
▼ + stars: | 2024-07-30 | by ( Brenda Goodman | ) edition.cnn.com time to read: +9 min

In 2017, a stronger vaccine, Shingrix, became available. “While research into whether vaccines affect dementia risk continues, people should be aware that there are other factors that have definitively been linked to an increased dementia risk. This study also found that the new shingles vaccine was associated with a larger degree of benefit than the older one. Although the findings are intriguing, the association needs more study before researchers can know for sure that the shingles vaccine is definitively behind the benefit. So for the time being, the best reason to get a shingles vaccine is still to avoid the misery of shingles.

Persons: stow, Shingrix, that’s, ”, Paul Harrison, ” Harrison, Dr, Andrew Doig, ” Doig, it’s, Sheona Scales, Scales, Sanjay Gupta, Phil Dormitzer Organizations: CNN, US Centers for Disease Control, Nature, GlaxoSmithKline, GSK, University of Oxford, University of Manchester, Alzheimer’s Research, Alzheimer’s Association International Conference, Oxford, CNN Health Locations: United States

☆ Anxiety may increase risk of dementia, study finds
▼ + stars: | 2024-07-29 | by ( Kristen Rogers | ) edition.cnn.com time to read: +8 min

ingwervanille/Moment RF/Getty ImagesMore than 55 million people worldwide have dementia, a number expected to increase to 139 million by 2050. Previous studies exploring the relationship between anxiety and dementia have largely measured participants’ anxiety at one point in time, providing mixed conclusions — but how long someone’s anxiety lasts is an important aspect worth considering, the authors argued. Researchers measured participants’ anxiety at the first and second assessments. Someone’s anxiety was considered resolved if they had anxiety only at the time of the first wave. “This study agrees with earlier studies that therapy aimed at alleviating anxiety can help reduce risk for (Alzheimer’s disease).

Persons: ”, Kay Khaing, Glen R, Finney, ” Finney, wasn’t, “, Rudolph Tanzi, Dr, Joel Salinas, Isaac Health, Salinas wasn’t, Tanzi, Khaing, ” Khaing, ” Tanzi Organizations: CNN, American Geriatrics Society, Hunter New, Hunter New England Health, Getty, Australian Department of Health, American Academy of Neurology, McCance, Brain Health, Massachusetts General Hospital, NYU Langone Health, ”, National Alliance, Mental Locations: Hunter New England, Newcastle, Australia, Pennsylvania, Massachusetts, Boston, ” Salinas

☆ Long-term exposure to wildfire smoke linked to increased risk of dementia diagnosis, new study finds
▼ + stars: | 2024-07-29 | by ( Maya Davis | ) edition.cnn.com time to read: +6 min

The researchers measured the impact of PM2.5 - air pollution particles that are 2.5 microns or smaller in diameter – from wildfire smoke as well as other sources, such as motor vehicles and factories. The research also indicates that associations between wildfire smoke and dementia diagnoses are most pronounced among people from racially and ethnically minoritized groups and in high-poverty areas. What you can doIndividuals can protect themselves from air pollution, including wildfire smoke, by staying indoors on poor air quality days. Home air filtration systems, including box fan air circulation, can also significantly improve indoor air quality, she said. “Our paper underscores that [wildfire smoke] is potentially an important one for individual patients and their providers who are who are curious what steps they can take.”

Persons: ”, Holly Elser, Maria Carrillo, they’ll, ” Elser, Dr, Sanjay Gupta, Carillo, there’s Organizations: CNN, International Conference, University of Pennsylvania, Alzheimer’s Association, Western, Get CNN, CNN Health Locations: Southern California, California, Canada, Greece, Western United States, Hawaii

☆ Alzheimer’s blood test catches 90% of early dementia cases, study finds
▼ + stars: | 2024-07-28 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +10 min

CNN —A combined blood test for cognitive decline has a 90% accuracy rate in determining whether memory loss is due to Alzheimer’s disease, a new study found. “The p-tau217 blood test is turning out to be the most specific for Alzheimer’s and the one with the most validity. “These are absolutely transformational times.”How does a p-tau217 blood test work? The results of the blood tests were then measured against patient diagnoses provided by Swedish primary care doctors and specialists. “There’s no one more bullish on these tests than I am, but Alzheimer’s blood tests aren’t fully definitive yet,” he said.

Persons: CNN —, Sebastian Palmqvist, ” Palmqvist, ”, Maria Carrillo, Carrillo, “ You’re, that’s, ” Carrillo, “, ” Tau tangles, Richard Isaacson, Oskar Hansson, ” Hansson, Hansson, Isaacson, ” Isaacson Organizations: CNN, Lund University, “, Alzheimer’s Association, International Conference Locations: Sweden, Alzheimer’s, Florida, United States, Philadelphia

☆ A doll, old letters and house keys: How displaced Palestinians are holding onto identity
▼ + stars: | 2024-07-27 | by ( Billy Stockwell | Sana Noor Haq | ) edition.cnn.com time to read: +14 min

“I cried for my area, my house, and everything around me,” Al-Hasanat told CNN in June. Several Palestinians told CNN they could take only their most significant personal items on long and hazardous journeys of displacement. Israeli strikes destroyed several of the university’s buildings in the early days of the war, Palestinian news agency WAFA reported. Students told CNN days spent on campus have been replaced by repeated displacement and bloodshed. Courtesy Raghad Ezzat HamoudaWith no end to the war in sight, other Palestinians told CNN they have held onto their house keys as a reminder of home.

Persons: Ahmed Al, Hasanat, Al, ” Al, “ Ayten, Dad, ’, ‘, ’ ”, Khan Younis, Ahmad Salem, “, ” Ahmed Al, Fadi Adwan, WAFA, ”, Haya Ismail, Refaat Alareer, Ismail, Dina, Dr, ” Ismail, Fadi, Rochelle Davis, –, Adwan, Ezzat Hamouda, Hamouda, Tamam –, Raghad Ezzat, Scott Webster, Israel, Davis, Samah, Ayten Organizations: CNN, United Nations, Bloomberg, Getty Images Israel, Hamas, Ministry of Health, Islamic, of Gaza, UN, Ministry of Education, Higher, Students, Georgetown University, “, Palestine, IDF, Government Media Office, Museum of, Palestinian, University of Sydney, Amnesty, Getty, Shifa, UNICEF, Government Media, Palestinian Ministry of Health, West Bank Locations: Gaza, Al, Mughraqa, Palestine, Israel, Palestinian, Rafah, Gaza City, Deir Al, Beit Lahia, Ramallah

☆ Biden’s Oval Office address now hands debate over democracy to Harris
▼ + stars: | 2024-07-25 | by ( Stephen Collinson | ) edition.cnn.com time to read: +9 min

In his primetime Oval Office address on Wednesday, Biden ceded the political stage to Kamala Harris, ushering in an unusual period heading into the election where the vice president, not the president, will lead their party. It’s been the honor of my life to serve as your president,” Biden said. “But … the defense of democracy, which is a stake, I think (is) more important than any title,” Biden said. One of the most significant implications of Biden’s decision is that he’s now putting his entire political legacy in someone else’s hands. But if Harris prevails over Trump, Biden’s actions and thinking spelled out in Wednesday’s address will be more likely to be remembered in his own terms — as a selfless political move motivated by deep patriotism.

Persons: Joe Biden, Donald Trump, Biden, Kamala Harris, Harris, —, It’s, ” Biden, ”, he’s, Trump, “ Thomas Jefferson, George Washington, Abraham Lincoln, Franklin Roosevelt, Benjamin Franklin’s, “ America’s, didn’t, Ronald Reagan, ” Reagan, “, Barack Obama’s, Shakespeare’s Macbeth Organizations: CNN, Democratic Party, Democratic, Republican, Trump Locations: Gaza, America, Atlanta, Kings, United States of America, Washington

☆ Brain Care Score may also predict depression, study finds
▼ + stars: | 2024-07-23 | by ( Kristen Rogers | ) edition.cnn.com time to read: +6 min

CNN —Scientists announced in December the successful creation of the Brain Care Score, a tool for assessing dementia or stroke risk without medical procedures. That score, which also helps patients and doctors identify beneficial lifestyle changes, may now also be able to predict the odds of developing depression later in life, according to a new study. The 21-point Brain Care Score, or BCS, refers to how a person fares on 12 health-related factors regarding physical, lifestyle and social-emotional components of health. “The Brain Care Score is a simple tool designed to help anyone in the world answer the question, ‘What can I do to take better care of my brain?’” said study author Dr. Jonathan Rosand, cofounder of the McCance Center for Brain Health at Massachusetts General Hospital and lead developer of the BCS, in a news release. The higher a participant’s score, the lower their risk of brain disease.

Persons: ”, ’ ”, Jonathan Rosand, Richard Isaacson, Isaacson, “, we’ve, ” Isaacson, Sanjula Singh, that’s Organizations: CNN —, Psychiatry, McCance, Brain Health, Massachusetts General Hospital, BCS, Harvard Medical School Locations: “, Massachusetts, Boston, United Kingdom, Florida

☆ Election Live Updates: Republicans Leave Convention Unified Around Trump
▼ + stars: | 2024-07-19 | by ( Jim Rutenberg | Adam Nagourney | ) www.nytimes.com time to read: +74 min

And there was great, great sorrow. They’re going to be OK. They’re going to be doing very well. Now he’s going to get on the plane in a little while and he’s going to go back home to his wife. Great, great student at Yale. So many — just so many heroes, so many great, great people.

Persons: Dana, Bob, ”, Lee, you’ll, it’s, didn’t, Nobody, “, I’m, Corey Comperatore, David Dutch, James Copenhaver, We’re, Corey, Helen ., David, James, Dan Newlin, Dan, Trump, —, Aileen Cannon, I’ve, Don, Kimberly, Ivanka, Jared, Eric, Lara, Tiffany, Michael, Barron, he’s, “ Dana won’t, That’s Lee Greenwood, … Eric, Crazy Nancy Pelosi, They’ve, Jason, Jason Aldean, Vance, Usha, He’s, He’ll, MAGA, ” MAGA, I’ll, you’re, nobody’s, We’ve, Somebody’s, they’re, It’s, can’t, We’ll, don’t, “ I’m, we’ll, Biden, They’re, that’s, you’ve, I’d, gee, You’d, That’s what’s, Donald Trump, That’s, There’s, Tom Homan, Brandon Judd, They’ll, Obama, They’d, “ You’ve, we’re, we’ve, Hannibal Lecter, Dwight D, Eisenhower, Jocelyn Nungaray, Rachel Morin, Rachel, Laken Riley, horrifically, Viktor Orban, what’s, Bush, it’ll, Kim Jung Un, Sam Brown, Sam, You’ve, Abdul, Don’t, You’re, Ronald Reagan, America’s, Franklin Graham, Franklin, Billy Graham, he’d, soldiered Organizations: of Pennsylvania, Secret Service, Service, Democrat, Republican Party, Republican, Democrats, America, Yale, ISIS, Space Force, Energy, Apple, Trump, Republican Senate, White, Republicans, United Auto Workers, Social Security, Border Patrol, ICE, ”, Lambs, University of Georgia, “, U.S, Senate, Washington, D.C, Yankee, Win Locations: America, United States, Butler Township, of, Pennsylvania, Florida, Ohio, Milwaukee, Wisconsin, Asia, Europe, Taiwan, Korea, Philippines, China, Russia, Ukraine, Israel, Iran, Germany, Mexico, Nevada, United States of America, There’s, South America, Africa, Middle East, Venezuela, Caracas, El Salvador, Houston, Los Angeles, Maryland, Hungary, “ Russia, Georgia, Crimea, Syria, Iraq, North Korea, Afghanistan, Bagram, Cuba, Miami, U.S.A, Wisconsin , Wisconsin, Washington, Japan, Delaware, Valley Forge, Yorktown, Gettysburg, Midway

☆ What a Trump presidency could mean for the dollar and the stock market
▼ + stars: | 2024-07-09 | by ( Nicole Goodkind | ) edition.cnn.com time to read: +6 min

There are other reasons the dollar has been propelled higher as some European and Asian currencies have seen lackluster growth. A strong dollar makes US exports more expensive and reduces the profits of American companies operating overseas when earnings are converted back to dollars. And while a strong dollar lowers the cost of imported raw materials, it can boost inflation and hurt foreign investments. The families of victims of two fatal crashes of the 737 Max oppose the deal, the department said. Beyond the fatal crashes of the 737 Max jets, the company has faced a series of questions about the safety and quality of its planes.

Persons: it’s, Donald Trump, Joe Biden, Trump, ”, Lisa Shalett, Morgan Stanley, Louis Navellier, Jeanne Sahadi, Read, Max, Chris Isidore Organizations: CNN Business, Bell, New York CNN, Federal Reserve, Fed, Republican, Morgan Stanley Wealth Management, Navellier, Associates, New York Federal Reserve, Boeing, Justice Department, Alaska Airlines Locations: New York, ”, China, Japan, United States

☆ Money problems can be an early sign of dementia
▼ + stars: | 2024-07-08 | by ( Jeanne Sahadi | ) edition.cnn.com time to read: +8 min

When a family member who has been fairly responsible with money all their lives becomes careless with their finances, it may be one sign of as-yet-undiagnosed dementia. “The harmful financial effects of undiagnosed memory disorders exacerbate the already substantial financial pressure households face upon diagnosis,” the researchers wrote. Two parents with dementia, one daughter’s efforts to reduce financial worryJayne Sibley, who lives in the United Kingdom, knows the pain and stress of dealing with the financial behaviors that can signal dementia. Her mother also would take money out of the cash machine two to three times a day and give it to anyone who asked. Of course, no amount of advanced financial planning can alleviate the heartbreak of watching a loved one with dementia decline.

Persons: Marcey Tidwell, ”, Tidwell, Karen Lemay, “, Lemay, hadn’t, ” Lemay, Jayne Sibley, ” Sibley, Sibley, doling, Ditto, ’ ”, ” Tidwell Organizations: New, New York CNN, New York Federal Reserve, Johns Hopkins Bloomberg School of Public Health, US National Institute, Aging Locations: New York, Bloomington , Indiana, Ottawa, Canada, United Kingdom, Sibley

☆ Biden says the debate was a bad night. Here’s how doctors would evaluate if it was something more
▼ + stars: | 2024-07-06 | by ( Jen Christensen | ) edition.cnn.com time to read: +12 min

CNN —President Joe Biden said Friday that his poor performance in last week’s debate was a bad night but not evidence of a serious condition. When asked on Friday whether he’s had cognitive tests and an exam by a neurologist, Biden said no. Biden gave no indication he would be willing to have such tests conducted in the aftermath of his debate performance. “So, again, pretty important for a job like president,” Ranganath added. “Part of those evaluations will look at the overall health of the individual, from neurologic health to also cognitive health,” she said.

Persons: Joe Biden, ” Biden, George Stephanopoulos, “, “ you’re, ”, Sanjay Gupta, ” Gupta, he’s, Biden, …, Charan Ranganath, — doesn’t, “ It’s, ” Ranganath, John Rowe, —, Rowe, ” Rowe, Donald Trump, aced, they’ll, Emily Rogalski, ” Rogalski, what’s, Brad Dickerson, Dickerson, ” Dickerson, Dr, Ranganath, Nadia Kounang, John Bonifield Organizations: CNN, ABC News, University of California, Columbia University, Mini, University of Chicago’s, Alzheimer’s Research Care, Harvard Medical School, Massachusetts General Hospital, Aetna, Mount, Mount Sinai NYU Health, Get CNN, CNN Health Locations: Davis, Montreal, Massachusetts, Mount Sinai

☆ Dr. Sanjay Gupta: It’s time for President Biden to undergo detailed cognitive and neurological testing and share his results
▼ + stars: | 2024-07-05 | by ( Dr. Sanjay Gupta | ) edition.cnn.com time to read: +10 min

Biden was examined by his physician after the debate to check on a cold, the White House said, but it was a “brief check” and not a physical. Biden and his aides have said it was a “bad night.” The White House press team said Biden had a cold but did not take any medications to treat symptoms. The White House has rejected requests from the press to release more medical records and question Biden’s physician, Dr. Kevin O’Connor. PoolWe often hear that observing a candidate on the campaign trail is the best assessment of the individual’s physical and cognitive health. Back in 2020, Biden said he was “constantly tested” by the work of running for president.

Persons: Joe Biden, Lewy, Biden, Karine Jean, Pierre, it’s “, Donald Trump, Trump’s, he’d, Trump, Bruce Aronwald, ” Trump, Jay Olshansky, Jean, Dr, Sanjay Gupta, “, Nancy Pelosi, Kevin O’Connor, Biden’s, O’Connor, Sen, John McCain —, —, John McCain, you’ve, ”, Amanda Sealy Organizations: CNN, United States, White, Trump, School of Public Health, University of Illinois, White House, Democratic, CNN Health Locations: Montreal, Chicago

☆ FDA approves Eli Lilly Alzheimer’s drug, expanding treatment options in the U.S.
▼ + stars: | 2024-07-02 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +1 min

A sign with the company logo sits outside of the headquarters campus of Eli Lilly and Company on March 17, 2024 in Indianapolis, Indiana. The Food and Drug Administration on Tuesday approved Eli Lilly 's Alzheimer's drug donanemab, expanding the limited treatment options for the mind-wasting disease in the U.S. The agency approved the treatment, which will be sold under the brand name Kisunla, for adults with early symptomatic Alzheimer's disease, according to the company. "Having multiple treatment options is the kind of advancement we've all been waiting for — all of us who have been touched, even blindsided, by this difficult and devastating disease." It's a long-awaited win for Eli Lilly after donanemab faced obstacles in its path to market.

Persons: Eli Lilly, Joanne Pike, donanemab Organizations: Company, The, Drug Administration, U.S, Alzheimer's Association, FDA Locations: Indianapolis , Indiana, U.S

☆ In new criteria for Alzheimer’s, some see much-needed progress while others fear profit may be driving ‘diagnostic creep’
▼ + stars: | 2024-07-01 | by ( Brenda Goodman | ) edition.cnn.com time to read: +12 min

CNN —With another pricey Alzheimer’s disease treatment expected to receive an approval decision soon, the nonprofit Alzheimer’s Association has published the final version of its new diagnostic criteria for the disease. Together with another protein, tau, which makes fibrous tangles that block the communication of nerve cells, they are considered a hallmark of Alzheimer’s disease. “There’s no evidence for it,” said Dr. George Perry, a neurobiologist and editor of the Journal of Alzheimer’s Disease. Two members of the panel were employees of the Alzheimer’s Association, which also takes funding from pharmaceutical companies. Widera says he hopes that in the next round of guidelines, the Alzheimer’s Association will consider the risks involved.

Persons: There’s, –, donanemab, “, ”, George Perry, Adriane Fugh, Berman, haven’t, Maria C, Carrillo, Alzheimer’s, It’s, Eric Widera, Widera, it’s, Aduhelm, Karl Herrup, Clifford Jack, ” Jack, “ It’s, Niles Franz, ” Franz, Dr, Sanjay Gupta, Franz, ” Widera Organizations: CNN, Alzheimer’s Association, Food and Drug Administration, FDA, Georgetown University, University of California San, American Geriatrics Society, Abbott Labs, University of Pittsburgh School of Medicine, Mayo Clinic, Nature Medicine, federal National Institute, Aging, Alzheimer’s Association International, National Institute, National Institutes of Health, NIA, Alzheimer’s, National Academy of Medicine, CNN Health, Association Locations: University of California San Francisco

☆ Embattled Alzheimer’s Researcher Is Charged With Fraud
▼ + stars: | 2024-06-28 | by ( Apoorva Mandavilli | More About Apoorva Mandavilli | ) www.nytimes.com time to read: 1 min

A scientist whose research has been at the center of controversy over an Alzheimer’s drug candidate has been charged with fraud. Dr. Wang’s studies underpinned research into a diagnostic test for Alzheimer’s disease and simufilam, a drug in advanced clinical trials. Simufilam’s manufacturer, Cassava Sciences, a pharmaceutical company based in Texas, has said the drug improves cognition in Alzheimer’s patients. Alzheimer’s disease affects roughly six million Americans — a number that is expected to double by 2050 — and promising treatments generate tremendous excitement. Cassava’s stock soared after each round of reported results from its trials.

Persons: Hoau, Yan Wang, — Organizations: City College of New, National Institutes of Health, Sciences Locations: City College of New York, Texas

☆ Gena Rowlands Has Alzheimer’s Decades After ‘The Notebook’
▼ + stars: | 2024-06-26 | by ( Reggie Ugwu | More About Reggie Ugwu | ) www.nytimes.com time to read: +1 min

Gena Rowlands has Alzheimer’s disease, a late-life challenge for the Oscar-nominated actor who captivated Hollywood in the 1970s with her performance in “A Woman Under the Influence” and later portrayed a character with dementia in “The Notebook.”Rowlands’s son, Nick Cassavetes, the director of “The Notebook,” revealed the diagnosis in a recent interview with Entertainment Weekly, telling the magazine that she had been living with the disease for five years. “She’s in full dementia,” he said. “And it’s so crazy — we lived it, she acted it, and now it’s on us.”A former theater and television actress, Rowlands, 94, made 10 films across four decades with John Cassavetes, the independent film pioneer who was also her husband. She was nominated for the Academy Award for best actress for two of them: “A Woman Under the Influence” (1974), in which she plays a wife and mother who cracks under the burden of domestic harmony, and “Gloria” (1980), about a woman who helps a young boy escape the mob.

Persons: Gena Rowlands, Oscar, ”, Nick Cassavetes, “, Rowlands, John Cassavetes, “ Gloria ” Organizations: Hollywood, Entertainment, Academy

☆ ‘The Notebook’: One of the saddest romantic movies of all time has now been making us cry for 20 years
▼ + stars: | 2024-06-25 | by ( Marianne Garvey | ) edition.cnn.com time to read: +3 min

CNN —If you’re in need of a good cry, release your tears and rewatch “The Notebook” as it turns 20 on Tuesday. The beloved romance movie, starring Ryan Gosling and Rachel McAdams as a young couple separated by class, released on June 25 2004. “It’s also a story of memory.”Here are five unforgettable exchanges from “The Notebook” movie:• “So it’s not gonna be easy. I’ll be seeing you.” Noah to Allie• “Now, say you’re a bird.”“If you’re a bird, I’m a bird.” Allie and Noah• “Why didn’t you write me? I wrote you everyday for a year.”“You wrote me?”“Yes… it wasn’t over, it still isn’t over.” Allie and Noah

Persons: Ryan Gosling, Rachel McAdams, Nick Cassavetes, Nicholas Sparks, James Garner, Gena Rowlands, Noah Calhoun, Allie Hamilton, Cassavetes, ” Cassavetes, Rowlands, “, Allie, she’s, ” Sparks, “ It’s, ” Noah, Allie • “, I’m, ” Allie, Noah • “, ” “, Noah Organizations: CNN, Entertainment, CBS Locations: South Carolina

☆ Has your loved one had money problems before being diagnosed with Alzheimer’s or dementia? Tell CNN your story
▼ + stars: | 2024-06-24 | by ( Jeanne Sahadi | ) edition.cnn.com time to read: 1 min

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☆ The Promise of Weight-Loss Drugs
▼ + stars: | 2024-06-24 | by ( Dani Blum | ) www.nytimes.com time to read: +2 min

In the past two years, Ozempic has become a synonym for weight loss. Ozempic was weight loss; weight loss was Ozempic. Scientists believe the drugs are about to revolutionize several fields of medicine, such as cardiology and endocrinology. If these trials prove successful, the drugs may extend many lives by years, save billions in medical costs and divide public health into before-and-after epochs. These drugs, called GLP-1s (glucagon-like peptide 1 receptor agonists), mystify even the scientists who study them.

Persons: Ozempic, slimmed, we’ve, mystify Organizations: Food and Drug Administration

☆ Can playing word games reduce Alzheimer’s risk? Dr. Gupta answers viewer’s question
▼ + stars: | 2024-06-20 | by ( Meneida Bailey | ) edition.cnn.com time to read: 1 min

☆ Opinion | Life With Alzheimer’s: Families’ Stories
▼ + stars: | 2024-06-19 | by ( ) www.nytimes.com time to read: +1 min

To the Editor:Re “My Mom Showed Me Life With Alzheimer’s Is Worth Living,” by Stephen Gettinger (Opinion guest essay, June 10):I watched my mom disintegrate over a decade, the dementia robbing her of any semblance of quality to her days. And I wonder, if and when it comes, will I deal with it with resignation or grace? Will I be able to accept my fate and cherish what remains, or rail against the gods for robbing me of my essential being? Watching my mom disappear from view was one of the hardest things both my sister and I could ever imagine. Robert S. NussbaumFort Lee, N.J.To the Editor:The beautifully written and supportive essay by Stephen Gettinger about his mother’s journey with Alzheimer’s and his own diagnosis should be read by all families and patients facing this debilitating disease.

Persons: Stephen Gettinger, Sinatra, Robert S, Nussbaum Fort Lee, Alzheimer’s Organizations: Worth Locations: N.J

☆ How much of Alzheimer’s disease is preventable? Dr. Gupta weighs in
▼ + stars: | 2024-06-18 | by ( Dr. Sanjay Gupta | ) edition.cnn.com time to read: 1 min

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