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☆ Healthy living may battle cognitive decline even with signs of dementia in the brain, study suggests
▼ + stars: | 2024-02-05 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

CNN —Living a healthy lifestyle with a focus on a nutritious diet, regular exercise, minimum alcohol consumption and other healthy habits can help keep your brain sharp into old age, doctors say. But what if your brain already has signs of beta amyloid or tau — two of the hallmark signs of Alzheimer’s and other brain pathologies? Will a healthy lifestyle still protect you from cognitive decline? Not everyone who has signs of Alzheimer’s or vascular dementia goes on to develop cognitive issues, but many do. In fact, “a higher healthy lifestyle score was associated with better cognition even after accounting for the combined burden of brain pathologies,” according to Yaffe and Leng.

Persons: ”, Dr, Klodian, Richard Isaacson, “, Isaacson, wasn’t, —, Kobus, Lewy, Yue Leng, Kristine Yaffe, Yaffe, San Francisco Weill Institute for Neurosciences . Leng, Leng, it’s Organizations: CNN, Rush Institute, Healthy Aging, Rush University, “, University of California, San Francisco Weill Institute for Neurosciences . Locations: Chicago, Florida, San

☆ Dementia and sport: These rugby players represented their country in their 20s, by their 40s, they had early onset dementia
▼ + stars: | 2024-02-05 | by ( Amy Woodyatt | ) edition.cnn.com time to read: +17 min

Popham’s wife, Mel, would have a conversation with her husband and an hour later he would have “no recollection,” he tells CNN Sport. Richard Boardman, the lawyer representing the claimants, told CNN Sport that this is causing an “existential threat” to the game. “As far as the brain is concerned, it doesn’t matter what sport is played,” Michael Grey, a neuroscientist at the University of East Anglia, told CNN Sport. Nowinski, a WWE wrestler turned neuroscientist, told CNN Sport that head injury protocols need to go beyond treating concussion. The paper, which looked at 412 Scottish former international male rugby players aged 30 and above and 1,236 members of the public who had been matched for age, sex and socioeconomic status, found that the rugby players’ risk of a dementia diagnosis over time was just over twice as high.

Persons: Alix Popham, Mel, ”, Popham, ” Popham, I’ve, Alix Popham of Wales, Pat Riordan of, Stu Forster, Lenny Woodard, Woodard, “, “ I’d, I’d, ” Woodard, Brook Joyner, Richard Boardman, ” Michael Grey, Chris Nowinski, Scott McIntyre, Nowinski, ” Ann McKee, ” Boardman, Roger Goodell, University of East Anglia Boardman, Grey, –, ” Steve Borthwick of, Alun Wyn Jones, Paul Harding, ” Grey, McKee, it’s, aren’t, we’re, shouldn’t, weren’t, ” Alix Popham Organizations: CNN, CNN Sport, rugby, Rugby, Alix Popham of Wales offloads, Pat Riordan of Canada, Wales, Getty, World Rugby, Rugby Football Union, RFU, Welsh Rugby Union, WRU, Springer, University of East, National Football League Players, Wrestling Entertainment, WWE, Washington Post, Boston University CTE Center, British Medical, Exercise, NFL, NFL.com, University of East Anglia, RBS, Nations, University of Glasgow, Boston University, University of Sydney, Scottish, ’, “ Rugby, England Rugby, Boston University’s CTE, CTE Locations: France, Wales, England, Canada, Nantes, Europe, University of East Anglia, American, Woodward, Boston

☆ Factories in developing Asia may have seen the worst of manufacturing slump
▼ + stars: | 2024-02-01 | by ( Clement Tan | ) www.cnbc.com time to read: +3 min

Photographer: Linh Pham/Bloomberg via Getty Images Bloomberg | Bloomberg | Getty ImagesMost developing economies in Asia might have left the worst of the broad manufacturing slowdown behind in 2023, according to a series of private surveys released Thursday. South Korea's S&P manufacturing purchasing managers' index recorded its first expansionary reading since June 2022 at 51.2 in January, up from 49.9 in December. "The health of the South Korean manufacturing sector registered a renewed improvement at the start of 2024. Growth was reportedly reflective of increased domestic and international orders, particularly for new products," Bhatti added. These private PMI surveys are typically seen as one of several leading indicators of economic activity in the respective economies.

Persons: Linh Pham, Usamah Bhatti, Bhatti, Annabel Fiddes Organizations: Wind Corp, Vung, Renewables, International Energy Agency, Bloomberg, Getty Images Bloomberg, Getty, P Global Market Intelligence, Vietnam, ASEAN, PMI, International Monetary Fund, IMF, " Companies Locations: Tan Thanh, Ba, Vung Tau Province, Vietnam, Asia, China, Taiwan, Malaysia, Thailand

☆ Biogen drops controversial Alzheimer's drug Aduhelm to focus on Leqembi, experimental treatments
▼ + stars: | 2024-01-31 | by ( Annika Kim Constantino | ) www.cnbc.com time to read: +2 min

Biogen on Wednesday said it will discontinue the sale and development of its older and highly controversial Alzheimer's drug Aduhelm to refocus the company's efforts to treat the memory-robbing disease. The biotech company will focus on rolling out Leqembi, a newly approved Alzheimer's drug it developed with Japanese drugmaker Eisai . The U.S. Food and Drug Administration greenlit Aduhelm in 2021 under a program that fast-tracks promising treatments. The company said it will redistribute a large portion of the resources associated with Aduhelm to the rest of its Alzheimer's drug portfolio. Among the other Alzheimer's drugs Biogen has in development is BIIB080, which targets a toxic protein called tau in the brain.

Persons: Biogen, Aduhelm Organizations: U.S . Food, Drug Administration, CNBC PRO Locations: U.S, Swiss

☆ Rare cases of possible Alzheimer’s transmission uncovered in recipients of discontinued medical treatment
▼ + stars: | 2024-01-29 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +9 min

All five adults had growth hormone deficiency as children and received pituitary growth hormones prepared in a specific way from cadavers. The treatment approach was discontinued after cases of a rare brain disorder called Creutzfeldt-Jakob disease were found to be associated with the administration of contaminated human growth hormone from cadavers. Although Alzheimer’s is not a prion disease, some separate research suggests that the two proteins that are hallmarks in Alzheimer’s disease — amyloid beta and tau — behave like prions. “This study suggests that in very rare circumstances Alzheimer’s disease may be transmitted between humans via human growth hormone from deceased donors. “I’m also intrigued by how these results may inform potential therapeutic targets and strategies in the future,” Isaacson said, regarding Alzheimer’s disease.

Persons: John Collinge, Jakob, Creutzfeldt – Jakob, Alzheimer’s, ” Collinge, ’, –, ” Dr, Susan Kohlhaas, ” Kohlhaas, “ It’s, Dr, Richard Isaacson, ”, Isaacson, “ I’m, ” Isaacson, “, Gargi Banerjee, ” Banerjee, James Galvin, Sanjay Gupta, ” Galvin, Lewy Organizations: CNN, Nature, University College London Institute, University College London, National Hospital for Neurology, Neurosurgery, Alzheimer’s Research, Science Media, Comprehensive, Brain Health, University of Miami Health, CNN Health Locations: United Kingdom, United States, United, Florida, UHealth, Creutzfeldt

☆ TikTok's Lunden and Olivia Stallings are straight people's favorite lesbian couple. What do they owe queer fans?
▼ + stars: | 2024-01-25 | by ( Kate Taylor | ) www.businessinsider.com time to read: +29 min

Lunden and Olivia told me their mission as influencers was to "represent and inspire others to be their authentic self." Advertisement"I did feel represented by them," Asia said, but the tweets "showed me that they are still white women." "We are especially confident in our sexuality and the way that we feel and who we are," Olivia told me. Lunden and Olivia told me they want to advocate for all LGBTQ+ people, including those who don't look like them. It's a chance, the couple told me, to combat the hate and negativity LGBTQ+ parents face.

Persons: Lunden Stallings, Olivia Bennett, Monique Lhuillier, Lunden, Taylor Swift, Stallings, David Yurman, preppy, Olivia, TikTok, Kendrick Brinson, who's, you've, Madison Mathews, sunnies, peck, they'd, Brooklynites, Remington, Zeta Tau, Olivia DMed Lunden —, Justin Bieber, snapbacks, haven't, Lunden's, Ellie Goulding's, Olivia couldn't, Caroline Bayne, Lunden's TikTok, Zara, Mercedes, Sophie, It's, Jackie J, Jackie, There's, Bud Light, Dylan Mulvaney, influencers, They've, KenzKustomz, Krysten Stein, Black influencers, Stein, Hill, millennials Organizations: Naylor, People, Business, Alabama, Chevrolet, New York Post, Daily Mail, Madison, University of Central, Jacksonville State University, Zeta Tau Alpha, University of Alabama's, University, Minnesota, BI, Braves, Rover, Pride, Nielsen, Saks, University of Illinois Locations: Roswell , Georgia, Asia, Olivia, Charleston, LoveShackFancy, Powder Springs , Georgia, Atlanta, Blytheville , Arkansas, University of Central Arkansas, Alabama, Roswell, Austin, RushTok, Alpharetta, Charleston , South Carolina, Southern, Publix, Fayetteville , Arkansas, University of Illinois Chicago

☆ New blood test that screens for Alzheimer’s may be a step closer to reality, study suggests
▼ + stars: | 2024-01-22 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

Alzheimer’s disease, a brain disorder that affects memory and thinking skills, is the most common type of dementia, according to the National Institutes of Health. “A blood test being negative speeds up the investigation for other causes of the symptoms and this is just as important,” Ashton said. Isaacson, who has researched blood biomarkers in people with no or minimal cognitive complaints, likened testing blood samples for signs of Alzheimer’s disease to how people undergo routine blood tests for high cholesterol. It is possible that currently available treatments for Alzheimer’s disease would work better in those diagnosed early in this way,” he said. The combination of a simple screening test with an effective treatment for Alzheimer’s disease would have a dramatic impact for individuals and for society.”

Persons: ” Nicholas Ashton, Ashton, ”, Kaj Blennow, Henrik Zetterberg, antiamyloid, immunoassay, ” Ashton, Richard Isaacson, ” Isaacson, Isaacson, ‘, “, Dr, Sanjay Gupta, David Curtis, ” Curtis Organizations: CNN, University of Gothenburg, National Institutes of Health, Quest Diagnostics, Alzheimer’s, Alzheimer’s Association, Get CNN, CNN Health, University College London, Science Media Locations: Sweden, United States, Wisconsin, Pau, Florida

☆ I kicked my son out during the peak of his drug addiction. He recovered, and I'm grateful for the years I didn't think I'd get with him.
▼ + stars: | 2023-12-27 | by ( Jennifer Cannon | ) www.businessinsider.com time to read: +5 min

My son started smoking marijuana in high school and things quickly escalated to heroin. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . The 10-year detour his life took after high school spanned all things concerning whether he would make it out of this alive. Standing at the kitchen sink one summer morning in 2010, the warm prickle of hives took shape down my legs. AdvertisementWhen I first learned Bryant was smoking marijuana, I thought, "he's in high school."

Persons: I'm, what's, —, Bryant, I'd, Cesar Deleon, I've, Weeks Organizations: Service, University of North, Engineers, Anonymous, FAU, Tau Beta Pi Locations: Florida, California, University of North Florida, Lake Worth

Grimes alleged Elon Musk spent less than half his time in 2023 in Texas, in recent legal filings. Musk still spends two to three days a week in California, Grimes alleged. AdvertisementElon Musk — who moved Tesla's headquarters from California to Texas in 2021— has been spending less than half his time in the Lone Star State, Grimes alleged in recent legal documents. Musk quietly sued Grimes in Texas court in September to establish a "parent-child" relationship with the kids. While Grimes has said the child was with Musk in Texas over her objection, the details around the arrangement, and how she responded, are unclear.

Persons: Grimes, Elon Musk, Musk, —, Elon, Claire Boucher, X, Christopher Melcher, Walzer Melcher, Tesla, Peter Walzer Organizations: Service, Lone Star State, Tau, Business, Musk, Street Journal, Montessori, Twitter, SpaceX Locations: Texas, California, Austin , Texas, Austin, Hawthorne , California, Brownsville , Texas, Bay Area . Texas, Starbase, SpaceX's, Boca Chica , Texas, Snailbrook, Boring, Bastrop , Texas, State, San Francisco, Palo Alto

☆ Elon Musk says his kids' safety is at risk unless a Texas judge restricts access to his custody battle with Grimes
▼ + stars: | 2023-12-02 | by ( Erin Snodgrass | Grace Kay | ) www.businessinsider.com time to read: +7 min

Elon Musk filed new documents in Texas court asking a judge to restrict access to his custody battle. Attorneys for Musk want a judge to issue a protective order before he agrees to sit for a deposition. Musk also asked a judge to suspend public access to documents in the case, arguing the potential risk to his children outweighs any public interest in the high-profile custody battle. AdvertisementMusk was first to strike, however, quietly suing Grimes in Texas court in September to establish a "parent-child" relationship with the kids. AdvertisementA protective order would guarantee the information Musk reveals during a deposition remains private and inaccessible to the public, Melcher added.

Persons: Elon Musk, —, Grimes, Musk, Claire Boucher, X, Grimes didn't, Christopher Melcher, Walzer Melcher, Melcher, Elon, Chesnot, Frazer Harrison, countersued, CHANDAN KHANNA, Jack Sweeney, Sweeney, he'd, Bob Iger Organizations: Musk, Service, Business, Tau, BI, Elon, Getty, Circuit, SpaceX, Twitter, Sweeney, Summit, Disney Locations: Texas, California, Americas, Austin , Texas, Ukraine

☆ Researchers return to Alzheimer's vaccines, buoyed by recent drug success
▼ + stars: | 2023-11-20 | by ( Julie Steenhuysen | ) www.reuters.com time to read: +6 min

The renewed interest in Alzheimer's vaccines follows a promising first attempt more than 20 years ago that was abandoned after 6% of study volunteers developed life-threatening brain inflammation known as meningoencephalitis. Dr. Reisa Sperling, an Alzheimer's researcher at Mass General Brigham in Boston, said she believes vaccines will play an important role as researchers look to prevent Alzheimer's. She is considering vaccines for her next study in asymptomatic people with Alzheimer's proteins in their blood, but not enough to register on brain scans. Alzheimer's vaccines are still in the early stages and will require large, years-long trials to show they work. Generating a strong immune response is critical for such vaccines, which would typically be given to older individuals with weaker immune systems, he said.

Persons: Brian Snyder, Eli Lilly's, Reisa Sperling, Brigham, “, ” Sperling, Walter Koroshetz, Mei Mei Hu, Vaxxinity, Hu, Michael Rafii, Rafii, Andrea Pfiefer, Johnson, Prothena, Gene Kinney, Julie Steenhuysen, Caroline Humer, Bill Berkrot Organizations: Alzheimer Research, Brigham, Women's, REUTERS, Rights, U.S . Food, Drug Administration, Mass, National Institutes of Health, UB, University of Southern, Johnson, Bristol Myers Squibb, Thomson Locations: Boston , Massachusetts, U.S, Boston, Taiwan, University of Southern California

☆ Bigger belly in 40s and 50s linked to early signs of Alzheimer’s disease
▼ + stars: | 2023-11-20 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

CNN —Inflammation from belly fat may be linked to the early stages of Alzheimer’s disease decades before symptoms begin, new research has found. “That’s important because brain atrophy is another biomarker of Alzheimer’s disease,” Raji said. “These are people who, if they do develop Alzheimer’s disease, it won’t happen for another 20 or 25 more years. “Regardless of weight, people should find out if they have hidden visceral fat,” Raji said. Visceral fat ‘easier to lose’There’s good news: Visceral fat responds well to diet and exercise, Raji said.

Persons: “, ”, Richard Isaacson, Isaacson, Cyrus Raji, St . Louis, ” Raji, Dr, Mahsa, Raji, ” Isaacson, It’s Organizations: CNN, Washington University School of Medicine, Radiology Society, Cleveland Clinic, Mayo Clinic Locations: Florida, St .

☆ Sweet spot for HRT may reduce dementia risk by nearly a third, study says
▼ + stars: | 2023-11-02 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +8 min

Just how harmful or helpful hormone replacement therapy may be also depends on the type of hormones that are prescribed, especially at older ages. Estrogen-only hormone therapy can be prescribed if the uterus has been removed via hysterectomy. Scientists are developing a new generation of hormone replacement called selective estrogen receptor modulator, or SERM. Scientists are working on new forms of hormone replacement therapy that go directly to the brain, thus making them safer for menopausal women. In addition, some women are not candidates for hormone replacement therapy, perhaps due to family history, heart conditions or clotting disorders.

Persons: hasn’t, “, ”, Lisa Mosconi, Mosconi, Richard Isaacson, ” Isaacson, gynecologists, midlife, ” Mosconi Organizations: CNN, Weill Cornell Medicine, “ Locations: New York City, midlife, Florida

☆ Elon Musk paraded his son X at a Formula One event in Texas in the middle of a custody battle with Grimes over where the boy primarily lives
▼ + stars: | 2023-10-25 | by ( Lauren Steussy | Kelsey Vlamis | Erin Snodgrass | ) www.businessinsider.com time to read: +4 min

Elon Musk's current custody battle with Grimes hinges on where his children with the musician live. At a Formula 1 event in Texas, Musk was pictured waving to the crowd with his son X on his shoulders. AdvertisementAdvertisementTesla CEO Elon Musk made an appearance at Sunday's F1 race in Austin, Texas, with his son X perched on his shoulders. The 3-year-old is at the center of a parental rights battle between Musk and his sometimes-partner, musician Grimes. X, meanwhile, is "only absent from California over [Boucher's] objection," according to Grimes' October 6 request for Musk's case to be thrown out, previously obtained by Insider.

Persons: Elon Musk's, Grimes, Musk, X, —, Elon Musk, Claire Boucher, Musk's Cybertruck, nannies, Peter M, Walzer Melcher, Grimes didn't Organizations: Service, Tau, SpaceX, Mercedes, Musk Locations: Texas, Austin , Texas, California, Musk's

The Alzheimer's drug LEQEMBI is seen in this undated handout image obtained by Reuters on January 20, 2023. Eisai/Handout via REUTERS/File Photo Acquire Licensing RightsBOSTON, Oct 25 (Reuters) - An injected version of Eisai (4523.T) and Biogen's (BIIB.O) Alzheimer's drug Leqembi works as well as the current intravenous version at removing toxic brain plaques, according to an analysis presented by Eisai on Wednesday. The Japanese drugmaker's review compared data for 72 patients with early Alzheimer's given Leqembi by subcutaneous injection to prior pivotal trial results from 898 patients who received the drug by infusion. Blood concentration levels of the drug were 11% higher with subcutaneous Leqembi than the IV version. Roll-out of IV Leqembi, which has an annual list price of $26,500, has been slow.

Persons: Eisai, Leqembi, ”, Eric Reiman, Priya Singhal, Biogen, Michael Irizarry, Alzheimer's, Julie Steenhuysen, Deena Beasley, Bill Berkrot, Leslie Adler Organizations: Reuters, REUTERS, Rights, Banner Alzheimer's Institute, ARIA, Thomson Locations: Handout, Boston, Los Angeles

☆ Doubts abound about a new Alzheimer’s blood test
▼ + stars: | 2023-10-18 | by ( Judith Graham | ) edition.cnn.com time to read: +10 min

The Quest Diagnostics blood test, AD-Detect, measures elevated levels of amyloid-beta proteins, a signature characteristic of Alzheimer’s. But Alzheimer’s researchers and clinicians aren’t convinced the Quest test is backed by sound scientific research. Though blood tests for Alzheimer’s are likely to become common in the years ahead, the Alzheimer’s Association said it’s premature to offer a test of this kind directly to consumers. Because the science behind blood tests for Alzheimer’s is still developing and because “patients may not really understand the uncertainty of test results,” Edelmayer said, the Alzheimer’s Association “does not endorse the use of the AD-Detect test by consumers.”Quest’s blood test is one of several developments altering the landscape of Alzheimer’s care in the United States. The bottom line: Before taking a test, “older adults need to ask themselves, ‘Why do I want to know this?

Persons: aren’t, Alzheimer’s, Michael Racke, ”, there’s, Suzanne Schindler, St . Louis, That’s, ” Schindler, Racke, Meera Sheffrin, —, Rebecca Edelmayer, ” Edelmayer, Eric Widera, Dr, Sanjay Gupta, Emily Largent, ’ ”, Munro Cullum Organizations: Health, Diagnostics, Alzheimer’s Association, Quest, University of Michigan, International Conference, Washington University School of Medicine, Senior, Stanford Healthcare, The University of Michigan, FDA, National Institute, Aging, University of California, Get CNN, CNN Health, University, Pennsylvania’s Perelman, of Medicine, HIPAA, University of Texas Southwestern Medical Center, Kaiser Health, KFF Locations: U.S, San Diego, St ., United States, San Francisco

Most of the school burned down, but its leaders quickly got classes up and running at Sacred Hearts Mission Church 10 miles (16 kilometers) away. Sacred Hearts and other private schools across the state took in displaced public school students, such as Cuaresma, while offering a year of free tuition. Other students bused more than 45 minutes away to public schools on the other side of Maui or opted for remote classes. Debbie Tau’s two children won’t return to their Lahaina schools because she also is worried the air isn’t safe. Patrick Williams said the first time he saw his son Kupaʻa praying at Sacred Hearts reminded him of his own childhood in Mississippi.

Persons: ”, Cailee Cuaresma, “ I’m, Cuaresma, Tonata Lolesio, “, Lahaina , King Kamehameha III, Nāhiʻenaʻena, Tiffany Teruya, Puʻuwai, Debbie Tau’s, Patrick Williams, ’ ” Williams, Williams, Gabby Suzik, Suzik, ” Suzik, Charlene Ako, Ako, Maile Organizations: Lahainaluna High, Sacred Hearts School, Hearts Mission, Hearts, Workers, Assistance Dogs, Lahaina, Maui Preparatory Academy, Lahaina’s, Maui Prep Locations: LAHAINA, Hawaii, Maui, Lahaina, Lahaina , King, Kihei, COVID, Mississippi, Asuncion, Waiola

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Persons: Dow Jones

☆ Elon Musk and his kids with Grimes have strong ties to California, singer argues to get his Texas child custody case tossed
▼ + stars: | 2023-10-12 | by ( Jack Newsham | Grace Kay | ) www.businessinsider.com time to read: +5 min

Claire Boucher, better known as Grimes, asked a Texas judge to throw out Elon Musk's custody case. The musical artist Grimes has asked a Texas judge to throw out Elon Musk 's child-custody lawsuit filed last month, saying the case belongs in California, not Austin. In Musk's lawsuit , he claimed they lived together in Texas as recently as July 2023. He splits his time between six companies — with his private jets sometimes making multiple trips between Texas and California within a week. The lawsuit isn't the first sign of conflict between Musk and Grimes.

Persons: Claire Boucher, Grimes, Elon, —, Elon Musk, Tesla, Musk didn't, didn't, Chrisopher Melcher, Walzer Melcher, Melcher, Musk, Musk's, Walter Isaacson, Tesla's Austin gigafactory, Shivon Zilis Organizations: Service, SpaceX, Montessori, Twitter Locations: Texas, California, Austin, Los Angeles, Tesla's, San Francisco, Hawthorne , California, Boca Chica , Texas

☆ Elon Musk has custody of son X despite mother Grimes' objections, court doc says
▼ + stars: | 2023-10-12 | by ( Jack Newsham | Grace Kay | ) www.businessinsider.com time to read: +4 min

She told a Texas court that son X "is only absent from California over [her] objection." Grimes, the musician who has three children with Elon Musk , told a Texas court last week that their eldest son X Æ A-XII Musk isn't with her in California "over [her] objection." The artist, whose real name is Claire Boucher, asked a Texas court on October 6 to throw out Musk's child-custody case. Their oldest child, three-year-old son X, is "only absent from California over [Boucher's] objection," according to the document, obtained by Insider. In his biography on Musk, Walter Isaacson wrote that with X Musk had a "free-range" parenting style that was far from "doting."

Persons: Grimes, Elon Musk's, X, —, Elon Musk, Claire Boucher, Musk, Tesla, Tesla's, Walter Isaacson, X Musk, Walter Isaacson’s, Isaacson, Recep Tayyip Erdoğan, We're, Grimes —, Shivon Zilis Organizations: Tesla, Service, Variety, SpaceX Locations: California, Texas, Hungary, Tesla's gigafactory, Turkey, New York

☆ Blood tests needed for widespread Alzheimer's diagnosis on the way
▼ + stars: | 2023-10-11 | by ( Deena Beasley | ) www.reuters.com time to read: +6 min

Several Alzheimer's blood tests are in the works – and one is already being sold to consumers – but none have been established as accurate, formally approved by regulators or reimbursed by insurers. Researchers have been working for years on blood tests for Alzheimer's that can replicate these diagnostic tools. The need for blood tests has become more pressing since the FDA approved Leqembi in July. Accurate blood tests are expected to help identify which dementia patients actually have Alzheimer’s, the most common but not the only cause of dementia. "When there are widely available, scalable, sensitive and specific blood tests it will be an absolute game changer for Alzheimer's patients."

Persons: Denis Balibouse, Eli Lilly, Dr, Sarah Kremen, Eliezer Masliah, Eisai, Michael Irizarry, Roche, Bruce Jordan, Russ Paulsen, Deena Beasley, Caroline Humer, Bill Berkrot Organizations: Memory Centre, of Readaptation, University Hospital, REUTERS, FDA, Sinai Medical Center, Wednesday, Quest Diagnostics, National Institute, Aging, U.S . National Institutes of Health, C2N Diagnostics, Roche Diagnostics, Alzheimer's Association, RAND, Thomson Locations: Geneva, Switzerland, Leqembi, Eisai, Los Angeles, U.S

Grimes sued Elon Musk last month for physical custody of the former couple's three children. AdvertisementAdvertisementGrimes and Elon Musk's three children are not allowed to leave California after Grimes sued Musk last month for physical custody of the kids, according to court records obtained by Insider. Lawyers for Musk and Grimes declined to comment, and Musk didn't respond to a request for comment. AdvertisementAdvertisementIn his petition, Musk accused Grimes of moving to California "in an apparent attempt to circumvent jurisdiction" of Texas courts. It's not clear where Musk and Grimes' kids are currently living.

Persons: Grimes, Elon Musk, —, Elon Musk's, Musk, Claire Boucher, Neama, Holly Davis, Davis, Clive Mason, X, he'd, Musk's Organizations: Service, San, San Francisco Superior Court, Tau, West, Trial, Musk, Getty, Forbes, Twitter Locations: California, San Francisco, Texas, Grimes, Musk's Texas, Los Angeles, Austin , Texas, Austin, Turkey, New York

Grimes is seeking physical custody of her and Elon Musk's three kids, according to court documents. AdvertisementAdvertisementGrimes is suing Elon Musk and asking for physical custody of the three children they share, according to court records obtained by Insider. Grimes, whose legal name is Claire Boucher, is seeking physical custody of her and Musk's kids — 3-year-old X and 1-year-olds Exa and Tau — as well as joint legal custody. Grimes' lawsuit also requests that Musk's suit be thrown out. Differentiating legal custody and physical custody allows parents to share decision-making and rights of access to the kids without an equal custody split, Davis said.

Persons: Grimes, Elon Musk's, Musk, —, Elon Musk, Claire Boucher, Tau —, Neama, Holly Davis, Kirker Davis, Davis, Recep Tayyip Erdoğan, We're, Shivon Zilis, Walter Isaacson, Zilis Organizations: Service, San Francisco Superior Court, San Francisco, West, SpaceX Locations: California, Los Angeles, Texas, Turkey, New York

☆ EXCLUSIVE: Elon Musk filed custody suit against Grimes first, asking for 'relationship' with his children
▼ + stars: | 2023-10-06 | by ( Jack Newsham | Grace Kay | ) www.businessinsider.com time to read: +5 min

Grimes filed a custody suit against Elon Musk in San Francisco late last month. But Insider learned Musk sued Grimes first, to "establish the parent-child relationship" with his kids. AdvertisementAdvertisementHeadlines around the world announced this week that Grimes had sued Elon Musk for custody of their three children, but it was Musk himself who first quietly sued Grimes last month, Insider has learned. In filings obtained by Insider, Musk said he wanted to "establish the parent-child relationship" with his and Grimes' children X, who is 3, and one-year-olds Exa (or Y) and Tau. Musk and Grimes have had a contentious relationshipIt's just the latest dust-up over the Musk children between Musk and Grimes, the musician with whom he's been in an on-again, off-again relationship since 2018.

Persons: Grimes, Elon Musk, Musk, —, X, Claire Boucher, weren't, It's, he's, Elon, Shivon Zilis, Walter Isaacson, Zilis, surrogates, she'd Organizations: Elon, Service, Lawyers, Musk, SpaceX Locations: San Francisco, California, Texas, Austin, Grimes

☆ Hot flashes are more dangerous than previously thought
▼ + stars: | 2023-09-27 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

Welcome to the hot flashes and other symptoms of approaching menopause — an experience experts say about 75% of women will share if they live long enough. Intense hot flashes could indicate an increased risk of Alzheimer's and heart disease in the future, new research found. The women were also fitted with sweat monitors to record their hot flashes on one of those nights. Frequent moderate to severe hot flashes can often last seven to 10 years, on average, and less frequent or severe hot flashes can last even longer, according to experts. “A lot of people actually underreport their hot flashes, saying they’re not having many when they really are,” Faubion said.

Persons: Peter Dazeley, ”, Stephanie Faubion, Faubion, Rebecca Thurston, “, Thurston, ” Faubion, they’ve, Thurston’s, they’re, Mary Carson Organizations: CNN, Bank, Getty, Mayo, Specialty Clinic, “, University of Pittsburgh’s Pitt Public Health, University of Pittsburgh Locations: Philadelphia, Jacksonville , Florida

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