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London — Novo Nordisk trimmed its full-year profit outlook Wednesday after reporting weaker-than-expected quarterly sales of its popular weight loss drug Wegovy. Chief Financial Officer Karsten Munk Knudsen in an interview called the market reaction unsurprising, given the market’s sensitivity to Novo’s mega-blockbuster drug Wegovy. Sales of Wegovy, Novo’s first-to-market weight loss drug, rose 53% to 11.66 billion crowns, well below the 13.54 billion crowns expected by analysts, while sales of Ozempic, a diabetes drug with the same active ingredient, also just missed expectations. Operating profit in the quarter rose 8% at constant exchange rates to 25.9 billion Danish crowns ($3.8 billion) compared with the 27.3 billion crowns forecast by analysts in an LSEG poll. All eyes on supplyNevertheless, Novo raised its sales growth outlook for this year to between 22% and 28% in local currencies from 19% to 27% previously.
Persons: Karsten Munk Knudsen, Wegovy, , Markus Manns, Lars Fruergaard Jorgensen, Eli Lilly, Jorgensen, Novo’s, Novo, Lilly Organizations: London, Nordisk, Novo, Union Investment, Barclays, Citi Locations: Germany, Danish, United States, Britain
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“This is the first study that actually looked at a relatively large number of patients for whether there is any neuroprotective effect in Alzheimer’s disease,” Edison said. The trial enrolled predominantly people with mild Alzheimer’s disease, measured by a test known as the Mini-Mental State Examination, a scale that goes up to 30. The GLP-1 drug class also includes Eli Lilly’s Mounjaro and Zepbound, which use the active ingredient tirzepatide, which mimics not just the hormone GLP-1 but another called GIP. But it hasn’t announced any trials of its GLP-1 drugs in Alzheimer’s. GLP-1 drugs can have side effects, though, primarily gastrointestinal problems like nausea and vomiting.
Persons: liraglutide, , , Maria Carrillo, Carrillo, Paul Edison, ” Edison, Edison, Eli Lilly’s Mounjaro, Alzheimer’s Lilly, hasn’t, Lilly, Lars Fruergaard Jorgensen, there’s, Dr, Sanjay Gupta, semaglutide Organizations: CNN, Alzheimer’s Association International Conference, Alzheimer’s Association, Novo Nordisk, Imperial College London, , Nordisk, ” Novo Nordisk, CNN Health, University of Oxford, Alzheimer’s Society, Alzheimer’s Locations: United Kingdom, Philadelphia, Alzheimer’s, ” Novo, Danish
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Read previewFans and critics alike hated "X-Men Origins: Wolverine" starring Hugh Jackman when it hit theaters back in 2009. Now, the first reviews for "Deadpool & Wolverine" suggest that the highly anticipated sequel could save the Marvel Cinematic Universe after several middling releases. AdvertisementIt's a far cry from the reaction to "X-Men Origins: Wolverine," which has a 38% rating on Rotten Tomatoes. But the hugely positive reception to "Deadpool & Wolverine" shows just how far both characters have come since "Origins." Fans will be pleased to know that critics are impressed with the story in the 2024 film, its violence, and crowd-pleasing cameos.
Persons: , Hugh Jackman, Ryan Reynolds, Reynolds, Dexerto's Cameron Frew, Nick Schager, Tom Jorgensen, Wade Wilson's, Magazine's Olly Richards, Kate Walsh, Robbie Collin Organizations: Service, Marvel, Business, Rotten, Los Angeles Times
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