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One of the most helpful things to do might be to get some exercise, according to a new study. “It gives us an idea of something that maybe we don’t always think about for treatment of insomnia,” Paruthi said. Regular exercise was associated with significantly better sleep, the study showed. There are plenty of reasons why physical activity may help in getting a good night’s rest. Physical activity helps regulate the body’s internal clock and promotes deeper, more restorative sleep,” Björnsdóttir said.
Persons: , Erla, sleepiness, David Neubauer, ” Björnsdóttir, Shalini Paruthi, ” Paruthi, Neubauer, Paruthi Organizations: CNN’s, CNN, Reykjavik University, Johns Hopkins University School of Medicine, Saint Louis University School of Medicine, American Academy of Sleep
Viking Therapeutics shares jumped more than 25% on Tuesday after the company said its experimental weight loss pill showed positive results in a small study and will enter the next stage of development later this year. The study results add to the excitement around the drugmaker's prospects in the budding weight loss drug market. Based on Tuesday's results, Viking plans to start a phase two trial of its weight loss pill later this year. Weight loss for those patients ranged up to 3.6% higher than those who received a placebo. Viking CEO Brian Lian said during a conference call on Tuesday that it's unclear "how durable" the weight loss is.
Persons: Eli Lilly, Viking, Brian Lian Organizations: Viking Therapeutics, Novo Nordisk, Viking
When I was diagnosed with breast cancer, I decided not to tell my kids. And with breast cancer, early detection is everything." Anna Sullivan took her two kids trick-or-treating just a few hours after her breast cancer diagnosis. My breast cancer diagnosis was early-onset and ER+, meaning that instead of chemotherapy, I was prescribed a five-year adjuvant endocrine therapy. Being able to talk openly about my cancer diagnosis has brought us closer as a family.
Persons: , Freddie, White, Snow, Alex, Max, It's, Anna Sullivan, hadn't, intently, I've, waaay, I'd Organizations: Service, OB
Rite Aid reaches bankruptcy settlement with lenders, DOJ, McKesson
  + stars: | 2024-03-26 | by ( ) www.cnbc.com   time to read: +2 min
The Rite Aid logo is displayed above a Ride Aid store on December 21, 2022 in Los Angeles, California. Pharmacy chain Rite Aid has reached a settlement with its lenders, the U.S. Department of Justice, and drug supplier McKesson Corp , clearing a path for Rite Aid to complete its bankruptcy case by late April, a company lawyer said Tuesday. "We have reached an agreement on all key points with all key economic stakeholders," Rite Aid attorney Aparna Yenamandra said at a bankruptcy court hearing in Trenton, New Jersey. Before it filed for bankruptcy, Rite Aid faced over 1,600 lawsuits alleging that pharmacy chain ignored red flags and illegally filled prescriptions for addictive opioid medication. Rite Aid received bankruptcy court approval to sell its pharmacy benefit company, Elixir, in January.
Persons: Aparna Yenamandra, Yenamandra, Andrew Rosenberg, Joshua Sussberg, Michael Kaplan, Kaplan Organizations: Pharmacy, U.S . Department of Justice, McKesson Corp, Aid, Rite Aid, Aid's, Brigade Capital Management, HG Vora Capital Management, Morgan Investment Management, U.S Locations: Los Angeles , California, Trenton , New Jersey
The market may see a new wave of stock splits, creating another growth catalyst for a market that wants to keep rallying, according to Strategas. The median gain of a stock 65 days post-split is 4.1%, compared to the S & P 500's median 2.7% gain during the same period. Stock splits do not change anything fundamentally about the company, but they generally make shares more attractive to the retail trader because of lower prices. Here are the highest-priced stocks in the S & P 500 that Strategas thinks investors could benefit from if they split. Another name on the list, pharmaceutical giant Eli Lilly , last announced a 2-for-1 stock split in September 1997.
Persons: Jason Trennert, Trennert, Strategas, Jensen Huang, CNBC's Jim Cramer, Eli Lilly Organizations: Micro Computer, Nvidia, Broadcom, Costco Wholesale
In his majority opinion in the case overturning Roe v. Wade, Justice Samuel Alito insisted that the high court was finally settling the vexed abortion debate by returning the “authority to regulate abortion” to the “people and their elected representatives.”Despite these assurances, less than two years after Dobbs v. Jackson Women’s Health Organization, abortion is back at the Supreme Court. In the next month, the justices will hear arguments in two high-stakes cases that may shape the future of access to medication abortion and to lifesaving care for pregnancy emergencies. These cases make clear that Dobbs did not settle the question of abortion in America — instead, it generated a new slate of questions. The first case, scheduled for argument on Tuesday, F.D.A. At issue is the law’s interaction with state laws that severely restrict abortion, like an Idaho law that bans abortion except in cases of rape or incest and circumstances where abortion is “necessary to prevent the death of the pregnant woman.”
Persons: Roe, Wade, Samuel Alito, Dobbs, America —, Organizations: Jackson, Health Organization, Supreme, Alliance, Hippocratic, Food, Labor Locations: America, Idaho
4 Takeaways From the Abortion Pill Arguments
  + stars: | 2024-03-26 | by ( Pam Belluck | ) www.nytimes.com   time to read: +1 min
A majority of the Supreme Court seemed inclined on Tuesday to reject a bid to sharply limit access to abortion pills. During about 90 minutes of argument, most of the justices seemed doubtful that the plaintiffs, who do not prescribe abortion pills or regularly treat abortion patients, even had standing to bring the challenge. The justices, including several in the conservative majority, questioned whether the plaintiffs could show that they faced the moral harm they claimed to suffer from the availability of the pill, mifepristone. The case centers on whether changes the Food and Drug Administration made in 2016 and 2021, which broadened access to the drug, would have to be rolled back. Those changes made it possible for patients to obtain prescriptions for mifepristone by telemedicine and receive abortion pills in the mail, which has greatly increased the availability of medication abortion.
Organizations: and Drug Administration, telemedicine
Meanwhile, Amazon 's pharmacy efforts added another wrinkle and Disney 's newest board member weighed in on the proxy fight underway at the entertainment giant. F YTD mountain F stock performance year-to-date. The divergence in stock performance was not great to see. AMZN YTD mountain AMZN stock performance year-to-date. To help offer the swift delivery, Amazon said it is leveraging artificial intelligence "to help pharmacists fill prescriptions quickly and accurately."
Persons: John Lawler, Ford, Jim Cramer, , Doug Herrington, we're, Jim, Morgan Stanley, James Gorman, Gorman, Trian Partner's Nelson Peltz, Jay Rasulo, We've, Peltz, Wendy's, Heinz, Jim Cramer's, Jim Farley, Bill Pugliano Organizations: Ford Motor, Ford, Bank of America Securities Auto Summit, Motors, Amazon Pharmacy, Worldwide Amazon Stores, Nvidia, CNBC, Disney, FactSet, Procter, Gamble, Unilever, Ford Motor Company, Technology, Getty Locations: , Monday's Homestretch, New York City, Los Angeles, Seattle , Miami, Indianapolis, Phoenix, Austin , Texas, China, Marshall , Michigan, Romulus , Michigan
CNN —Medicare shelled out $5.7 billion on Ozempic and other similar diabetes drugs in 2022, up from $57 million in 2018, according to a new KFF analysis. Medicare began covering Ozempic for people with diabetes in 2018, with Rybelsus and Mounjaro joining in 2019 and 2022, respectively. The KFF study examined gross spending, which does not take into account any rebates paid by drug manufacturers that would lower Medicare spending. The drugs’ popularity and prices could end up raising costs for both the federal government and Medicare enrollees broadly. Medicare could choose Ozempic and Rybelsus for its drug negotiation program as early as 2025, KFF wrote, which could lower spending on the medications.
Persons: Mounjaro, ” KFF, KFF Organizations: CNN, Medicare, US Food and Drug Administration, Congressional
If the Supreme Court sides with the plaintiffs and decides to roll back or invalidate Food and Drug Administration regulations on mifepristone, it would be the first time the court undercut the federal agency’s authority. The abortion pill case before the Supreme Court could have implications far beyond abortion, potentially undermining the regulatory system for all medicines in the United States. If the Supreme Court sides with the plaintiffs and decides to roll back or invalidate F.D.A. They would have to pick up mifepristone in person from a doctor and would have to visit the doctor three times during the medication abortion process. and not to abortion providers, some medication abortion services have been stockpiling mifepristone and may continue prescribing and mailing their supply.
Persons: , Matthew J, mifepristone Organizations: Drug, Food and Drug Administration, Northern, Northern District of, Trump, U.S ., Appeals, Fifth Circuit Locations: United States, Northern District, Northern District of Texas
The Food and Drug Administration on Tuesday approved a drug from Merck designed to treat a progressive and life-threatening lung condition in a win for both the drugmaker and for patients suffering from the rare disease. The condition refers to when the small blood vessels in the lungs narrow. He noted that the drug will be a "paradigm shift" for patients living with PAH. That includes reducing the risk of death or worsening of the condition by 84% compared to an existing drug alone. Those trials include late-stage studies on patients with more advanced PAH disease, and those who are within the first year after diagnosis.
Persons: Chris Schott, Eliav Barr, PAH, Barr, Merck Organizations: Merck, Drug Administration, JPMorgan, CNBC, Acceleron Pharma Locations: Rahway , New Jersey, U.S, Winrevair
CNN —A majority of Supreme Court justices appeared skeptical Tuesday of the idea of a nationwide ban or new limits on mifepristone, the primary drug used for medication abortions. At issue in the case are lower-court rulings that would have rolled back recent Food and Drug Administration decisions to ease access to the mifepristone. “What the court did … is enter sweeping nationwide relief that restricts access to mifepristone for every single woman in this country. Some anti-abortion activists see the law as an avenue to end medication abortion, and perhaps all kinds of abortions. Danco’s attorney said that this case was not an appropriate venue for the court to weigh the reach of the Comstock Act.
Persons: Roe, Wade, John Roberts, Neil Gorsuch, ” Roberts, Erin Hawley, interjected, Franklin Delano Roosevelt’s, , ” Gorsuch, Biden, , Elizabeth Prelogar, Brett Kavanaugh, ” Kavanaugh, Prelogar, Ketanji Brown Jackson, , Jackson, ” Jackson, Amy Coney Barrett, Barrett, Alito, Thomas, Samuel Alito, Clarence Thomas, ” Alito, Mifepristone, Comstock, mifepristone, Matthew Kacsmaryk –, Trump, , Kacsmaryk Organizations: CNN, Drug Administration, Conservative, FDA, Justice Department, Amarillo Division, Court, Northern, Northern District of, US, US Judicial Locations: mifepristone, FDA’s, Amarillo, Northern District, Northern District of Texas
The Amazon Pharmacy home screen is displayed on a laptop in Brooklyn, New York, on Nov. 17, 2020. The e-commerce giant said on Tuesday that it's rolling out same-day delivery of prescription medications in New York City and the greater Los Angeles area. To speed up deliveries, Amazon said it's using new, smaller facilities, stocked with the most common prescription medications for acute conditions. San Bernardino, Riverside and Anaheim, which are all in the LA area, are eligible for same-day prescription deliveries starting Tuesday. In October, Amazon began offering same-day prescription medication delivery in Seattle, Miami, Indianapolis, Phoenix and Austin, Texas.
Persons: Doug Herrington Organizations: Amazon Pharmacy, Amazon, Worldwide Amazon Stores, Station , Locations: Brooklyn , New York, New York City, Los Angeles, Bernardino, Riverside, Anaheim, LA, Seattle , Miami, Indianapolis, Phoenix, Austin , Texas, Station, Station , Texas, New York
If the Supreme Court agrees with the appeals court, the approval of mifepristone could be reset to where it stood before 2016, limiting telehealth access to medication abortion and reimplementing other restrictions. “Nevertheless, drug developers invest in new medicines because, if their investments succeed, FDA’s rigorous drug approvals and subsequent regulatory actions are sturdy enough to facilitate reliable returns. “And without necessary investment, drug development would freeze, stifling innovation and limiting treatment options for patients.”Of course, if the Supreme Court upholds the appeals court decision, the most immediate impact would be to mifepristone itself. “It is both my hope and my ‘bet’ that the court doesn’t uphold the 5th Circuit on the standing argument,” Cohen wrote. “But I have learned the Supreme Court is hard to predict much of the time.”
Persons: thalidomide, mifepristone that’s, , Daniel Grossman, ” Grossman, ” PhRMA, Glenn Cohen, Dr, Sanjay Gupta, Cohen, ” Cohen Organizations: CNN, Food and Drug, Federal Food, FDA, US, University of California San, Reproductive, Guttmacher Institute, Circuit, Appeals, Pharmaceutical Research, Manufacturers of America, Harvard Law School, CNN Health Locations: Massengill, University of California San Francisco, Texas
CNN —The fate of the abortion pill lies with the Supreme Court. The drug is still fully available while the Supreme Court deliberates. Medication abortion accounts for nearly two-thirds of all US abortions, according to 2023 data from the Guttmacher Institute. At least 5.9 million women have used mifepristone since its FDA approval in 2000. Telehealth for medication abortion is also effective and safe, according to a recent study.
Persons: Roe, Wade, mifepristone Organizations: CNN, Food, Guttmacher Institute Locations: Texas
Challenging Abortion, Again
  + stars: | 2024-03-25 | by ( Emily Bazelon | ) www.nytimes.com   time to read: +1 min
How safe is it to take abortion pills? The case could curtail Americans’ access to mifepristone, the first pill taken in a two-drug regimen for a medication abortion. A decision in the plaintiff’s favor would change the landscape of abortion not state by state, like the effects of the 2022 ruling that overturned Roe v. Wade, but across the country. Post-Roe AmericaThe abortion opponents who sued the government in tomorrow’s case, F.D.A. v. Alliance for Hippocratic Medicine, are frustrated by how common abortion has remained.
Persons: Roe, Wade, Margot Sanger, Katz, Claire Cain Miller Organizations: Alliance, Hippocratic Locations: United States
CNN —The Supreme Court on Tuesday will hear its first abortion case since the 2022 reversal of Roe v. Wade and upheaval of reproductive rights in America. All the while, public regard for the Supreme Court has degenerated. Supreme Court Justice Stephen Breyer is photographed at his home in Cambridge, Massachusetts, in September 2015. Dirck Halstead/The LIFE Images Collection/Getty Images Breyer and his daughter Chloe jog with Clinton in May 1994. Mai/The LIFE Images Collection/Getty Images Breyer works in his office with his staff of clerks in June 2002.
Persons: Roe, Wade, Joe Biden, Donald Trump, Dobbs, Biden, Elizabeth Prelogar, mifepristone, Prelogar, what’s, , Susan B, Anthony Pro, , Evelyn Hockstein, Breyer, Stephen Breyer, Justice Ketanji Brown Jackson, Samuel Alito, Hodges, Trump, , ” Breyer, Damon Winter, Stephen, Irving, Anne, Charles ., Chloe, Nell, Michael —, Joanna Breyer, Ira Wyman, Sygma, Byron White, Ruth Bader Ginsburg, John Harrington, Joanna, John Tlumacki, Bill Clinton, Clinton, Harry Blackmun, Dirck Halstead, Doug Mills, US Sen, Ted Kennedy, Laura Patterson, John Blanding, Colin Powell, George W, Bush, Mai, David Hume Kennerly, Seuss, Evan Vucci, Charles, Marcio Jose Sanchez, William Rehnquist, Clarence Thomas, David Souter, William Kennedy, Antonin Scalia, Sandra Day O'Connor, John Paul Stevens, Chip Somodevilla, John Roberts, Pablo Martinez Monsivais, Samuel Alito's, Gerald Herbert, Cole Mitguard, Mourning, Penni Gladstone, Clara Scholl, Elise Amendola, Nicholas Kamm, Michelle Obama, Barack Obama, Alex Wong, ABC's George Stephanopoulos, Heidi Gutman, Andrew Harrer, Hu Jintao, Eli, Shutterstock Breyer, Britain's Prince Charles, Mandel Ngan, Tom Williams, Carolyn Kaster, Ben Bradlee, Bill O'Leary, Pete Marovich, Stephen Colbert, Jeffrey R, Win McNamee, Elena Kagan, Neil Gorsuch, Anthony Kennedy, Sonia Sotomayor, Maureen Scalia, Andrew Harnik, Brett Kavanaugh, Amy Coney Barrett, Erin Schaff, Abraham Lincoln, George Washington, Saul Loeb, Ketanji Brown Jackson, Patrick, Fred Schilling, Matthew Kacsmaryk, Erin Hawley, GYN, Organizations: CNN, Alabama Supreme, Republican, Food, Drug Administration, FDA, Jackson, Health Organization, District of Columbia, America, United States Conference of Catholic Bishops, Alamo Women's, Reuters, Supreme Court, Democratic, Supreme, New York Times, Harvard Law School, Appeals, First Circuit, Circuit, Getty, White House, Airport, Boston Globe, US, Suffolk University Law School, Francisco's Lowell High School, San Francisco Chronicle, Belgium's Catholic University of Louvain, Georgetown University Law Center, Administrative, Administrative Conference of, Jewish American Heritage Month, Walt Disney Television, Bloomberg, White, Office, Committee, Washington Nationals, Washington Post, Financial Services, General Government, CBS, State, The New York Times, Library of Congress, Alliance, Hippocratic, Alliance for Hippocratic, OB, Department, Justice Locations: America, New York, Carbondale , Illinois, Cambridge , Massachusetts, Maine , Massachusetts, New Hampshire, Puerto Rico, Rhode Island, AFP, San Francisco, Lowell, Washington , DC, United States
Another report, published last week by the Guttmacher Institute, a research organization that supports abortion rights, found that medication abortions now account for nearly two-thirds of all abortions provided by the country’s formal health system, which includes clinics and telemedicine abortion services. The JAMA study evaluated data from overseas telemedicine organizations, online vendors and networks of community volunteers that generally obtain pills from outside the United States. Before Roe was overturned, these avenues provided abortion pills to about 1,400 women per month, but in the six months afterward, the average jumped to 5,900 per month, the study reported. The co-authors were a statistics professor at the university; the founder of Aid Access, a Europe-based organization that helped pioneer telemedicine abortion in the United States; and a leader of Plan C, an organization that provides consumers with information about medication abortion. Vendors in the study were vetted by Plan C and found to be providing genuine abortion pills, Dr. Aiken said.
Persons: Roe, , Abigail Aiken, Aiken Organizations: JAMA, Guttmacher Institute, University of Texas Locations: United States, U.S, Austin, Europe, India
Sam Bankman-Fried bilked FTX customers out of over $8 billion, according to prosecutors. AdvertisementAccording to federal prosecutors, Sam Bankman-Fried orchestrated one of the biggest criminal frauds in the history of the world. According to his lawyers, FTX's customers might get all their money back. According to prosecutors, Bankman-Fried was responsible for more than $11 billion in fraud overall between FTX customers and investors in FTX and Alameda Research. The recovered calculations, too, distort how much money customers are actually getting back.
Persons: Sam Bankman, , Fried, FTX, John J, Ray III, Ray, Lewis Kaplan, Kaplan, Sarah Krissoff, Cozen O'Connor, Krissoff, it's, Sarah Silbiger, Bankman, bitcoin, Rachel Maimin, Lowenstein Sandler, Barbara Fried, Mark Cohen, Jane Rosenberg Bankman, Maiman, Maimin, Caroline Ellison Organizations: Service, FTX, Bankman, Alameda Research, US, United States, Second Circuit, U.S . House Financial, Capitol, Reuters, K5 Global, Prosecutors, Wall, REUTERS, Business, of Prisons, Alemda Research Locations: FTX, Manhattan, New Jersey, New York, Washington , U.S
Mario Tama | Getty ImagesAmgen is taking a new approach as it tries to stand out in a crowded field of drugmakers racing to develop the next blockbuster weight loss drug. It's too early to say how competitive Amgen will be in the budding weight loss drug space, which Novo Nordisk and Eli Lilly have so far dominated. Goldman Sachs also projects that between 10 million and 70 million Americans will be taking weight loss drugs by 2028. The sustained weight loss in Amgen's study appears to contrast with results seen in clinical trials on Zepbound and Wegovy. An injection pen of Zepbound, Eli Lilly’s weight loss drug, is displayed in New York City, U.S., December 11, 2023.
Persons: Mario Tama, Eli Lilly, Goldman Sachs, Zepbound, Eli Lilly's, Amgen's MartiTide, Caroline Apovian, Apovian, Joe Buglewicz, MariTide, Holly Lofton, Eli Lilly’s, Brendan McDermid, Reuters Amgen's, William Blair, Matt Phipps, Phipps Organizations: Getty, Novo Nordisk, Pfizer, Viking Therapeutics, Therapeutics, Zealand Pharma, Boehringer, Center, Weight Management, Wellness, Brigham, Women's, Washington Post, NYU Langone Health, Reuters, William Blair & Company, CNBC Locations: Thousand Oaks , California, Oaks , California, Novo, New York City, U.S
While I had long believed in stashing cash in a pet emergency fund instead of paying for pet insurance, I was now sold. Pet insurance can pay for itselfAfter talking to a few fellow pet parents, I decided to get Embrace pet insurance. Now that I have pet insurance, I don't have to choose the cheapest pet insurance option because it's most affordable. I also have a pet emergency fundAs I said, before the constipation incident with my cat, I wasn't really keen on getting pet insurance. That's because pet insurance works a little differently than health insurance for humans.
Persons: , It's Organizations: Service, Business, American Pet Health Insurance Association
I had horrible weather and rough seas that left me feeling sick after the cruise. We had unusually rough seas throughout the entire cruiseI had some pretty bad weather throughout my cruise. AdvertisementMy brain knew I was on solid ground, but I felt like I was still on the cruise ship battling rough waves. I'm avoiding cruises from now onRelaxFoto.de/Getty ImagesI had some great laughs with friends on board despite the rough seas and lack of sunshine. One bad experience culminating with motion sickness on dry land is enough to make me want to avoid any cruises in the future.
Persons: , Thomas, St, Maarten, Brittany VanDerBill, I'd, didn't, I'm, it's Organizations: Service, Royal, Minnesota Locations: Caribbean, Royal Caribbean, St, Bahamas, Brittany
CNN —It’s been nearly 13 years since “The Oprah Winfrey Show” came to an end, but for viewers of her weight loss special on Monday night, it likely felt like Winfrey’s talk show was back. “An Oprah Special: Shame, Blame and the Weight Loss Revolution” featured Winfrey doing what she proved for 25 seasons on “The Oprah Winfrey Show” she can do better than just about anyone else: bring people together and get them talking – and listening – to each other. Winfrey, too, shared the pain she has felt at times in her weight journey. “It’s not a matter of willpower.”The medical experts addressed potential side effects of weight loss medications and factors and risks that should be considered before taking it as part of a multiifaceted care plan. Winfrey spoke about her use of weight loss medication as one “tool” to manage her weight, combined with hiking, running, weight resistance training and eating a healthy diet.
Persons: CNN — It’s, Oprah Winfrey, , , Winfrey, ” Winfrey, Scott Butsch, Amanda Velazquez, It’s, ” Butsch, “ It’s, Let’s Organizations: CNN, Obesity, Metabolic, Cleveland Clinic Locations: United States, Sinai, Los Angeles
The latest trends also suggest that medication abortion is a more common option than ever. Medication abortion has become more common than ever post-Roe, according to another new Guttmacher report. Nearly two-thirds of all abortions in the US in 2023 – an estimated 642,700 – were medication abortions, the report says. Medication abortion, also known as medical abortion, is a method by which someone ends their pregnancy by taking two pills – mifepristone and misoprostol – rather than having a surgical procedure. Misoprostol can be used on its own for a medication abortion and is a safe alternative, but research suggests that using both pills together is the gold standard.
Persons: Court’s Dobbs, , misoprostol, Dr, Sanjay Gupta, CNN’s Jen Christensen, Tierney Sneed Organizations: CNN, Guttmacher Institute, Guttmacher, US Food and Drug Administration, CNN Health Locations: United States
New York CNN —Elon Musk said he is “almost always” sober during his late-night — or, in some cases, very early morning — posting sessions on his social media platform, X. The billionaire Tesla CEO’s comment was made in an interview with journalist Don Lemon, during which Musk discussed his use of the medication ketamine. Musk denied that he overuses the medication, saying, “if you use too much ketamine, you can’t really get work done. Musk previously said advertisers who left X over concerns about antisemitic content could “go f**k yourself” and accused them of killing the company. “If you insist on censorship of the entire platform, even where your advertising doesn’t appear, then obviously we will not want them as an advertiser.”
Persons: New York CNN — Elon Musk, Tesla, Don Lemon, Musk, ” Musk, Lemon, , doesn’t, X Musk, Organizations: New, New York CNN, Tesla’s, X Locations: New York
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