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☆ Scientists Who Pioneered mRNA Vaccine Technology Win Nobel Prize in Medicine
▼ + stars: | 2023-10-02 | by ( Dominique Mosbergen | Peter Loftus | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones

☆ Katalin Karikó, Drew Weissman Win Nobel Prize for mRNA Vaccine Development
▼ + stars: | 2023-10-02 | by ( Dominique Mosbergen | ) www.wsj.com time to read: 1 min

Persons: Dow Jones

☆ Curtain comes up on new term for conservative US Supreme Court
▼ + stars: | 2023-10-02 | by ( John Kruzel | ) www.reuters.com time to read: +4 min

The U.S. Supreme Court building is seen in Washington, U.S., August 31, 2023. The conservative justices have shown assertiveness in major rulings in the past two years. The court has ended its recognition of a constitutional right to abortion, expanded gun rights, restricted federal agency powers, rejected affirmative action in college admissions and broadened religious rights. The justices are opening their annual term on the first Monday of October, in keeping with tradition. The term debuts with some justices under ethics scrutiny after revelations this year of their ties to wealthy conservative benefactors.

Persons: Kevin Wurm, Joe Biden's, Mark Pulsifer, Donald Trump, Pulsifer, Ruth Bader Ginsburg, Trump, Amy Coney Barrett, Ginsburg, John Kruzel, Will Dunham Organizations: U.S, Supreme, REUTERS, Rights, Purdue, Republican, resentencing, Consumer Financial Protection Bureau, Securities and Exchange Commission, U.S . Postal, Thomson Locations: Washington , U.S, Iowa, Texas, Florida

☆ Big Food vs. Big Pharma: Companies bet on snacking just as weight loss drugs boom
▼ + stars: | 2023-10-01 | by ( Amelia Lucas | ) www.cnbc.com time to read: +3 min

But food companies' major bets on snacking come as investors fear the looming danger of Big Pharma's blockbuster obesity and diabetes drugs Wegovy and Ozempic. Younger generations snack more often than older consumers, said Kelsey Olsen, food and drink analyst for market research firm Mintel. Millennials and Gen-Z consumers tend to eat smaller meals that are closer together, creating more occasions to grab a snack. At the same time, Novo Nordisk's Ozempic and Wegovy have taken off, fueled by prescriptions to help patients lose weight. Some patients even report developing aversions to foods with higher sugar and fat content — a category that includes many big snack brands.

Persons: Smucker, Big, Wegovy, snacking, Kelsey Olsen, Millennials, Morgan Stanley, Morgan Stanley's, General Mills Organizations: Hostess Brands, HSBC, Accenture, Novo Nordisk's Ozempic, Hershey, Mondelez, PepsiCo, General Locations: Seattle , Washington , U.S, U.S

On the heels of that decision, a federal appeals court invalidated a federal law that bars an individual who is subject to a domestic violence restraining order from possessing a firearm. A three-judge district court panel struck down the plan in January, saying that race had been the predominant motivating factor. Three years ago, the Supreme Court limited the independence of the CFPB by invalidating its leadership structure. The court’s decision could impact whether the SEC and other agencies can conduct enforcement proceedings in-house, using administrative courts staffed with agency employees, or whether such actions must be brought in federal court. “It’s difficult to think of any other recent First Amendment cases in which the stakes were so high,” Jaffer added.

Persons: Clarence Thomas, ”, Biden, Zackey Rahimi, John Roberts, Taiwan Scott, Thomas, Elizabeth Prelogar, Magnuson, Paul Clement, ” Clement, “, pare, George Jarkesy, Sackler, ” Prelogar, Jameel Jaffer, Jaffer Organizations: CNN, Gun Safety, South Carolina’s Republican, South Carolina State Conference of, NAACP, Democrat, Republican, National Marine Fisheries Service, Chevron, Natural Resources Defense, Stevens Fishery Conservation, Management, Independent, Consumer Financial, Federal Reserve, US, Federal Deposit Insurance Corporation, Securities, Exchange, US Securities and Exchange Commission, SEC, Social Security Administration, Circuit, Historic Purdue Pharma, Purdue Pharma, Sackler, Purdue, Facebook, YouTube, Columbia University’s Locations: United States, South Carolina, Alabama, Taiwan, Charleston County, Chevron, Florida, Texas

"We're definitely seeing a bit of a soft open in the IPO market", said Lizzie Reed, global head of the ECM syndicate desk at Goldman Sachs. Arm and Instacart shares briefly fell below their issue price, suggesting there is still some way before the IPO market fully recovers. Medical glass producer Schott Pharma (1SXP.F) debuted on the Frankfurt Stock Exchange on Thursday, with shares closing 16% above the IPO price. Klaviyo's shares are now trading at a 21% premium to their IPO price. "For the IPO market to open more broadly in the first quarter in 2024 ... we need the 2023 IPO cohort to continue to perform well," said Josh Weismer, head of U.S. ECM, Mizuho Americas.

Persons: Lizzie Reed, Goldman Sachs, IPOs, Robert Stowe ,, Suneel Hargunani, Schott, ThyssenKrupp, Hidrolectrica, Ross Devor, ”, Samir A, Gandhi, Stephane Gruffat, SoftBank, Josh Weismer, Echo Wang, Pablo Mayo, Anousha Sakoui, David Holmes Organizations: Bankers, ECM, Arm Holdings, Barclays, Citigroup, Schott Pharma, Frankfurt Stock Exchange, Thoma Bravo, Deutsche Bank, Nvidia, Apple, Qatar Investment Authority, U.S, Mizuho, Pablo Mayo Cerqueiro, Thomson Locations: United States, Europe, British, New York, U.S, IPOs, East, Africa, Romanian, Qatar, Mizuho Americas, London

During the third quarter, U.S. dealmaking contributed to a larger-than-usual share of global activity and offset a decline in volumes in Europe and Asia Pacific, accounting for about half of global volumes. Deal volumes in Europe and Asia Pacific fell 31% and 9%, respectively. To date, private equity deal volumes have slumped 48% to $313.73 billion, compared to the same period last year. Deal activity driven by activist shareholders was muted as several big-name activists reached settlements with corporate boardrooms. Dealmaking in technology, which typically accounts for the largest share of deal volumes, has fallen 51% so far this year.

Persons: Brendan McDermid, dealmaking, We're, Melissa Sawyer, Sullivan, Cromwell, dealmakers, headwinds, Tony Kim, Roark Capital's, ”, Andre Kelleners, Goldman Sachs, Naveen Nataraj, Kappa, WestRock, it’s, Rob Kindler, Weiss, Garrison, it'll, Anton Sahazizian, Anirban Sen, Timothy Gardner Organizations: REUTERS, Cromwell LLP, Asia Pacific, Investment, U.S . Steel, Centerview Partners, U.S . Investment, Evercore Inc, Cisco, Splunk Inc, Fidelity National Information Services, Reuters, Paul, Moelis, Thomson Locations: New York City, U.S, United States, Europe, Asia, Cleveland, Rifkind, Wharton, New York, London

U.S. President Joe Biden delivers remarks on Social Security and Medicare at the University of Tampa in Tampa, Florida, U.S. February 9, 2023. The ruling is the first to come from multiple lawsuits by drug companies and industry groups challenging the program. The drug price negotiation program is part of the Inflation Reduction Act, which Biden, a Democrat, signed last year. The Biden administration has repeatedly said there is nothing in the Constitution that prohibits drug price negotiations. Many other countries already negotiate drug prices.

Persons: Joe Biden, Jonathan Ernst, vindicating, Joe Biden's, Michael Newman, Biden, drugmakers, Newman, Karine Jean, Pierre, Donald Trump, Johnson, Januvia, Bristol Myers, Boehringer, Brendan Pierson, Nate Raymond, Costas Pitas, Alexia Garamfalvi, Bill Berkrot, Chris Reese, Leslie Adler Organizations: Social Security, University of Tampa, REUTERS, U.S, District, U.S . Chamber of Commerce, Medicare, Commerce, U.S . Justice, Republicans, Big Pharma, Republican, U.S . Centers, Medicaid Service, CMS, Bristol Myers Squibb, Pfizer, Johnson, Merck, Co's, Pharmaceutical Research, Manufacturers of America, Companies, Thomson Locations: Tampa , Florida, U.S, Dayton , Ohio, New York, Boston

☆ Schott Pharma shares climb in Frankfurt debut
▼ + stars: | 2023-09-28 | by ( Hannah Ward-Glenton | ) www.cnbc.com time to read: +1 min

Schott Pharma debuted on the Frankfurt stock exchange on Thursday at 30 euros per share, trading well above analyst expectations. Shares of the company were up 10% in the first minutes. Schott Pharma said sales were up 8.4% year-on-year for the first nine months of the 2023 fiscal year, hitting 670 million euros ($704 million) over the period. Schott Pharma has production and sales units across 33 countries. The Schott Pharma IPO is only the third new listing on the Frankfurt stock exchange this year and is expected to be the largest.

Persons: Andreas Reisse Organizations: Schott Pharma, Moderna Locations: Frankfurt

☆ Schott Pharma CEO discusses IPO
▼ + stars: | 2023-09-28 | by ( ) www.cnbc.com time to read: 1 min

Share Share Article via Facebook Share Article via Twitter Share Article via LinkedIn Share Article via EmailSchott Pharma CEO discusses IPOSchott Pharma CEO Andreas Reisse speaks to CNBC's Annette Weisbach on the company's IPO.

Persons: Andreas Reisse, CNBC's Annette Weisbach Organizations: Schott Pharma

Bottles of prescription painkiller OxyContin made by Purdue Pharma LP sit on a shelf at a local pharmacy in Provo, Utah, U.S., April 25, 2017. The settlements, which require a judge's approval, were disclosed in papers filed on Tuesday in federal court in San Francisco. The money is on top of $641.5 million that McKinsey already paid to resolve claims by state attorneys-general. McKinsey will pay $207 million to resolve claims by counties and municipalities, and another $23 million to resolve claims by public school districts. Aelish Baig, a lawyer for the local governments, in a statement called the deal "a strong outcome for the communities harmed by this crisis".

Persons: painkiller OxyContin, George Frey, Aelish Baig, McKinsey, Joe Biden's, Purdue Pharma's, Nate Raymond, Miral Organizations: Purdue Pharma, REUTERS, Companies Mckinsey, Company, Consulting, McKinsey, Co, U.S . Centers for Disease Control, U.S, Supreme, Purdue, Thomson Locations: Provo , Utah, U.S, San Francisco, United States, Boston

☆ The Big Pharma Stock Trade: Weight Loss Is In, Covid-19 Is Out
▼ + stars: | 2023-09-26 | by ( Charley Grant | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones

☆ Nvidia is targeting the ad industry as its next major chip-buying market
▼ + stars: | 2023-09-26 | by ( Lara O'Reilly | ) www.businessinsider.com time to read: +5 min

Jamie Allan, Nvidia director of business development for global agencies and advertising. For Nvidia, the advertising industry unlocks access to a client base that includes virtually every single major corporation across every industry. Taboola is using Nvidia GPUs to speed up its natural language processing, which analyzes articles and serves relevant content to users. More recently, it's been using Nvidia and OpenAI technologies to allow advertisers to create images within its platform. Allan said Nvidia intends to be more involved in the advertising industry discourse and help advise companies about the adoption of AI.

Persons: Nvidia's Jamie Allan —, —, Allan, Jamie Allan, Microsoft's Bing, Stephan Pretorius, There's, Adam Singolda, it's, Media.Monks, Jay Pattisall, Forrester, Nvidia, Jensen Huang Organizations: Nvidia, Big Tech, Google, Meta, EMEA, WPP, DENZA, AWS, Adobe, Media.Monks, Oracle, Cannes Lions, pharma, they're

☆ Cough syrup deaths overseas prompt US crackdown on toxic testing
▼ + stars: | 2023-09-26 | by ( Patrick Wingrove | ) www.reuters.com time to read: +6 min

Defendants and lawyers attend a court hearing in the case of child deaths linked to contaminated cough syrups, in Tashkent, Uzbekistan August 16, 2023. Cough syrups made in India and Indonesia have been linked to deaths of more than 300 children globally. The medicines were found to contain high levels of DEG and EG, leading to acute kidney injury and death. IMPORT ALERTSThe FDA warning letters give manufacturers an opportunity to fix quality control problems or face penalties. In addition, 13 U.S. makers of consumer products like earwax removers, nasal spray, hand soap and shampoo, including Lex, were threatened with possible seizures and injunctions by the FDA.

Persons: Stringer, Paul Hastings, Peter Lindsay, syrups, Lex, Charlene Paz, Greg Landry, Patrick Wingrove, Rishika, Joyce Lee, Michele Gershberg, Bill Berkrot Organizations: REUTERS, U.S, FDA, Drug Administration, EG, Reuters, South, South Korea's LCC, LCC, Daxal Therapeutics, Herbals, South Korea’s KM Pharmaceutical, Sangleaf Pharma, Massachusetts College of Pharmacy & Health Sciences, Thomson Locations: Tashkent, Uzbekistan, U.S, India, South Korea, Switzerland, Canada, Egypt, Washington ,, Indonesia, United States, Florida, South Korea's, South, New York, Rishika Sadam, Hyderabad, Seoul

☆ Indian shares seen opening lower amid sustained foreign selling
▼ + stars: | 2023-09-26 | by ( ) www.reuters.com time to read: +2 min

The new logo of the Bombay Stock Exchange (BSE) building is seen in Mumbai, India, July 12, 2023. REUTERS/Francis Mascarenhas/file photo Acquire Licensing RightsBENGALURU, Sept 26 (Reuters) - Indian shares are set to open lower on Tuesday, with higher-for-longer global interest rate expectations driving continuous foreign outflows from the domestic market amid subdued global sentiment. On Monday, the Nifty 50 (.NSEI) and the S&P BSE Sensex (.BSESN) closed mostly unchanged at 19,674.55 points, and 65,958 points, respectively. Foreign investors have been net sellers so far this month, offloading shares worth $1.36 billion, as of Sept. 22 after pouring in over $15 billion into Indian equities this year. On Monday, foreign institutional investors sold 23.33 billion rupees worth of shares, while domestic investors bought 15.79 billion rupees worth of shares, as per provisional exchange data.

Persons: Francis Mascarenhas, Ajith, Eileen Soreng Organizations: Bombay Stock Exchange, REUTERS, Rights, NSE, BSE, U.S, Federal, Of India, Realty, Hotel, & Realty, Sethuraman, Thomson Locations: Mumbai, India, Delhi, Bengaluru

☆ Uncle Sam Wants You—to Fight High Drug Prices
▼ + stars: | 2023-09-25 | by ( Joseph Walker | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones

☆ Jefferies upgrades this pharma stock, citing overlooked 'blockbuster' drug opportunities
▼ + stars: | 2023-09-25 | by ( Pia Singh | ) www.cnbc.com time to read: +2 min

AstraZeneca's tozorakimab drug for chronic obstructive pulmonary disease also seems underappreciated, with a potential to reach $4.5 billion in peak sales, according to Jefferies. The firm also suggests up to $3.5 billion in sales for AstraZeneca's eplontersen , a drug aimed at treating hereditary transthyretin-mediated amyloid polyneuropathy. The pharmaceutical giant is also poised to be the frontrunner in breast cancer treatments. Another one of AstraZeneca's breast cancer therapies, also being developed with Daiichi Sankyo, came out with positive news Friday. Its experimental precision drug datopotamab deruxtecan demonstrated an improvement in slowing the progression of a common type of breast cancer in a late-stage trial.

Persons: Peter Welford, Welford, AstraZeneca's, Jefferies, AstraZeneca's eplontersen, transthyretin, deruxtecan, Pascal Soriot's, — CNBC's Michael Bloom Organizations: AstraZeneca, Jefferies, AstraZeneca's, Japan's, pharma Locations: Japan's Daiichi

A few compounds picked by AI are now in development, but those bets will take years to play out. Reuters interviews with more than a dozen pharmaceutical company executives, drug regulators, public health experts and AI firms show, however, that the technology is playing a sizeable and growing role in human drug trials. The U.S. Food and Drug Administration (FDA) said it had received about 300 applications that incorporate AI or machine learning in drug development from 2016 through 2022. Without AI, Bayer said it would have spent millions more, and taken up to nine months longer to recruit volunteers. Finding real-world patients by mining electronic patient data can be done manually, but using AI speeds up the process dramatically.

Persons: Dado Ruvic, Jeffrey Morgan, Amgen, Badhri Srinivasan, Sameer Pujari, drugmaker Bayer, Bayer, Blythe Adamson, Roche, Richard Pazdur, Gen Li, John Concato, Natalie Grover, Martin Coulter, Julie Steenhuysen, Josephine Mason, David Clarke Organizations: Pharmaceutical Research, REUTERS, Pharmaceutical, Bayer, Novartis, Deloitte, U.S . Food, Drug Administration, Reuters, World Health, Flatiron Health, FDA, European Medicines Agency, FDA's Oncology, Excellence, Medical, FDA's Center, Drug, Research, Thomson Locations: U.S, Johannesburg, Texas, Finland, United States, London, Chicago

☆ Indian shares set for subdued open as Fed angst weighs
▼ + stars: | 2023-09-22 | by ( Sethuraman N R | ) www.reuters.com time to read: +2 min

A man walks past the new logo of the Bombay Stock Exchange (BSE) building in Mumbai, India, July 12, 2023. Already, foreign investors have been net sellers so far this month, offloading shares worth $996.2 million as of Sept. 20. Foreign institutional investors (FII) sold shares worth 31.11 billion rupees ($375.2 million), on a net basis, on Wednesday and 30.07 billion rupees worth on Thursday, according to stock exchange data. Domestic investors, meanwhile sold shares worth 5.73 billion rupees on Wednesday but bought shares worth 11.58 billion rupees on Thursday, the data showed. Meanwhile, Indian government bonds will be included in JPMorgan's widely tracked emerging market debt index from June 2024, the Wall Street bank said on Friday.

Persons: Francis Mascarenhas, Dalal, Aparna Iyer, Raja, Tesla, Archishma Iyer, Anisha Ajith, Savio D'Souza Organizations: Bombay Stock Exchange, REUTERS, Rights, NSE, Exchange, BSE, Federal Reserve, Wipro, LG Energy, Exide Industries, Power Systems, Glenmark Pharmaceuticals, Sciences, Glenmark Pharma, Teck Resources, Sethuraman NR, Thomson Locations: Mumbai, India, U.S, Asia, Pacific, Japan, Teck

☆ Blockbuster Cancer Treatment Stymied by Supply Chain—for Now
▼ + stars: | 2023-09-21 | by ( David Wainer | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones Organizations: pharma

☆ Contamination Is Found at Novo Nordisk Plant in U.S.
▼ + stars: | 2023-09-21 | by ( Peter Loftus | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones

☆ Japan says it continues to seek release of Astellas worker detained in China
▼ + stars: | 2023-09-21 | by ( ) www.reuters.com time to read: 1 min

TOKYO, Sept 21 (Reuters) - Japan is continuing its efforts to seek the prompt release of an employee ofAstellas Pharma (4503.T) who has been detained in China since March, Japan's top government spokesman said on Thursday. Chief Cabinet Secretary Hirokazu Matsuno was speaking at a press conference after Kyodo news agency reported on Wednesday that Beijing was expected to decide soon on whether to formally arrest the Japanese businessman, whom it detained on suspicion of espionage. Reporting by Kaori Kaneko Editing by Chang-Ran KimOur Standards: The Thomson Reuters Trust Principles.

Persons: Hirokazu Matsuno, Kaori Kaneko, Chang, Ran Kim Organizations: Astellas Pharma, Kyodo, Thomson Locations: TOKYO, Japan, China, Japan's, Beijing

☆ Barclays says this women's health pharma company could rally 48%
▼ + stars: | 2023-09-21 | by ( Hakyung Kim | ) www.cnbc.com time to read: +2 min

Organon is an undervalued global play and leader in women's specialty health, according to Barclays. The company, with a portfolio of about 60 treatments and products focused on women's health, was spun off from Merck in 2021 . Barclays analyst Balaji Prasad initiated coverage on Organon with an overweight rating. The company could also generate more than $1 billion in annual free cash flow during that span, he added. Organon's prescription birth control Nexplanon is the key driver to its women's health portfolio as the Nexplanon "pipeline continues to progress toward commercialization," he added.

Persons: Balaji Prasad, Prasad, Nexplanon, — CNBC's Michael Bloom Organizations: Barclays, Merck, Health Locations: Wednesday's

☆ Condom-shy India arouses interest of global contraceptive makers
▼ + stars: | 2023-09-21 | by ( Kashish Tandon | ) www.reuters.com time to read: +5 min

Such is the trend that the market is set to more than double to $1.7 billion by 2030, showed data from GrandView Research. By contrast, 19% of U.S. men use condoms every time they have sex, showed data from the National Center for Health Statistics. World Bank data showed that, in 2021, per capita gross domestic product crossed $2,000 - a threshold at which, in China in 2006, consumption jumped. Britain's Reckitt Benckiser Group (RKT.L) has launched new products under its Durex brand and expanded its "Birds and the Bees" rural marketing campaign. SOCIAL MEDIAIndia's market leader is domestic manufacturer Mankind Pharma (MNKI.NS) with a 33% share, ahead of Reckitt Benckiser at 14%, TechSci data showed.

Persons: Kazuhiro Kamio, Okamoto, Arvind Singhal, Miah Kiat Goh, Dwight, Mankind, Ashita Aggarwal, Kashish Tandon, Sumit Khanna, Rocky Swift, Dhanya Skariachan, Christopher Cushing Organizations: GrandView Research, Reuters Graphics Reuters, Okamoto Industries, National Center for Health Statistics, Technopak Advisors, Reuters, United Nations, Benckiser, ., Mankind Pharma, Social, Jain Institute of Management & Research, HDFC Securities Institutional, View Research, Thomson Locations: BENGALURU, India, Europe, Japan, China, U.S, S.P, Bengaluru, Ahmedabad, Rocky, Tokyo

☆ FDA Declines to Approve Epinephrine Nasal Spray, Asks for Additional Data
▼ + stars: | 2023-09-20 | by ( Alyssa Lukpat | ) www.wsj.com time to read: 1 min

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Persons: Dow Jones, 6f88483e Organizations: pharma, fda

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