Investors have been paying close attention to labor market data for any signs of weakening in the job market, as decreasing wage pressures and easing demand would help reduce inflation, giving the Fed the ammunition to begin decelerating with a 50-basis-point rate hike in December.
"From an employment standpoint things look really robust though, and that is putting some pressure on stocks."
According to preliminary data, the S&P 500 (.SPX) lost 16.26 points, or 0.42%, to end at 3,855.79 points, while the Nasdaq Composite (.IXIC) lost 97.62 points, or 0.90%, to 10,889.23.
Megacap growth names such as Amazon (AMZN.O) and Apple (AAPL.O), which have struggled since the Fed began raising interest rates, were once again under pressure.
Pfizer (PFE.N) rose after the drugmaker raised full-year sales estimates for its COVID-19 vaccine, while Eli Lilly (LLY.N) fell after trimming its profit forecast.