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☆ Arcturus: WHO watching XBB.1.16 as a coronavirus variant of interest
▼ + stars: | 2023-04-24 | by ( Brenda Goodman | ) edition.cnn.com time to read: +2 min

CNN —The World Health Organization has elevated the fast-growing Omicron sublineage XBB.1.16 as a new variant of interest, and says it is outcompeting the previously dominant XBB.1.5 in many regions. XBB.1.16 is a descendant of the recombinant XBB, which is a mashup of two BA.2 sublineages. On social media, the variant has been nicknamed Arcturus, like the brightest star in the northern celestial hemisphere. Currently, it is the dominant variant in India, where it is causing a wave of mostly mild illnesses. The XBB.1.5 variant continues to be the dominant cause of new infections in the United States, according to data from the US Centers for Disease Control and Prevention.

The cause of death was not immediately known and authorities will perform a post-mortem to find out more, the outlet reported. Uday – who was named by Indian citizens in a contest – was among 20 cheetahs airlifted to India over the past few months from Africa. The news of the deceased 6-year-old cheetah came just three weeks after his fellow feline, Sasha, died from a kidney infection. Laurie Marker, founder of the Namibia-based Cheetah Conservation Fund (CCF), which also helped with transferring the animals, said re-establishing a population is very difficult. In late March, the country welcomed four newborn cheetahs for the first time since the species disappeared from India more than 70 years ago.

☆ 'It totally backfired': The pitfalls of Alzheimer's genetic testing
▼ + stars: | 2023-04-21 | by ( Julie Steenhuysen | ) www.reuters.com time to read: +8 min

CHICAGO, April 21 (Reuters) - Wendy Nelson watched her mother slowly die of Alzheimer's disease, unable to move or swallow at the end. When her father's memory began to fail a year later, one of her two sisters doubted it could be Alzheimer's, Nelson said. THE TESTING REVOLUTIONUntil recently, most doctors tended not to order genetic tests to determine Alzheimer's risk, because there were no effective treatments to slow or prevent the disease. US regulators recommend genetic testing before starting treatment with Leqembi. Some members of families with increased genetic risk of Alzheimer's say it might be better not to know at all.

☆ Republican-led US House to vote on ban on transgender student athletes
▼ + stars: | 2023-04-20 | by ( Katharine Jackson | ) www.reuters.com time to read: +3 min

REUTERS/Elizabeth Frantz/File PhotoWASHINGTON, April 20 (Reuters) - The Republican-controlled U.S. House of Representatives is expected to vote Thursday on a bill that would ban transgender women and girls from competing in women's and girls' school sports, weighing in on an issue that has riled social conservatives. The measure would change the civil rights law known as Title IX to require that a student's sex be "based on an individual's reproductive biology and genetics at birth." Enacted in 1972, Title IX prohibits discrimination on the basis of sex in educational programs or activities that receive federal funding. The White House on Monday said in a statement that the bill would effectively deny access to sports for transgender students, even at the elementary school level. On Wednesday, Florida education officials voted to ban classroom instruction on gender identity and social orientation in public schools through high school.

☆ Republican-led ban on transgender student athletes passes US House, moves to Senate
▼ + stars: | 2023-04-20 | by ( Katharine Jackson | ) www.reuters.com time to read: +3 min

The House passed the measure by 219-203 but it has little chance of passing the Democratic-controlled Senate. "There's a reason why there's men and women's sports," McCarthy told reporters on the grounds of the Capitol, where he held a news conference with three female athletes who had competed with transgender athletes and lost. The White House on Monday said the bill would effectively deny access to sports for transgender students, even at the elementary school level. Twenty-one U.S. states already have transgender school sports bans in place, according to the Human Rights Campaign LGBTQ advocacy group. The Biden administration has proposed prohibiting schools from banning transgender athletes from playing on teams consistent with their gender identities, with exceptions possible for the highest levels of competition.

☆ Uganda: Leading scientists urge President Museveni to veto anti-LGBT bill
▼ + stars: | 2023-04-19 | by ( Catherine Nicholls | ) edition.cnn.com time to read: +3 min

CNN —A group of leading global scientists and academics have signed an open letter urging Ugandan President Yoweri Museveni to veto a hardline bill criminalizing homosexuality in the country. The Anti Homosexuality Bill 2023, which was passed by Ugandan lawmakers in March, is set to be either signed into law or vetoed by the president on Thursday. Before the bill was passed almost unanimously last month, President Museveni called on scientists to establish whether homosexuality was natural or learned. The letter has been signed by 15 leading scientists around the world, from countries including South Africa, the United States, Canada, the UK, Kenya, and Australia. Under the Anti Homosexuality Bill 2023, it would be a crime to even identify as lesbian, gay, bisexual, transgender, or queer.

☆ Ancient DNA reveals secrets of empire that pushed China to build its Great Wall
▼ + stars: | 2023-04-17 | by ( Katie Hunt | ) edition.cnn.com time to read: +5 min

Known as the Xiongnu, the empire saw conflict with great rival imperial China that resulted in the construction of the Great Wall, parts of which still stand today. Now, ancient DNA evidence, combined with the fruits of recent archaeological digs, is spilling the secrets of one of the era’s most powerful political forces. Excavation of the Xiongnu Elite Tomb 64 contains a high-status aristocratic woman at the site of a cemetery at Takhiltyn Khotgor in Mongolia's Altai Mountains. Golden icons of the sun and moon, symbols of the Xiongnu, decorate a coffin found in Elite Tomb 64 at the Takhiltyn Khotgor site. “And it was this potent legacy…that the Mongols took up when they created their own empire many more centuries later.”

☆ What is autism? An expert explains
▼ + stars: | 2023-04-12 | by ( Matt Villano | ) edition.cnn.com time to read: +10 min

To mark Autism Awareness Month, CNN talked with him about what autism is and what causes it. Geschwind: About a decade ago, the term “autism spectrum disorder” was adopted to encompass everything that we called autism into one rubric. When I started researching autism 25 years ago, the autism rate was 1 in 1,000 or 1 in 2,000. You can calculate a risk score for having autism based on genetics, (but) right now, the risk score for autism is not that predictive because we haven’t done enough research. The problem is that for many autistic individuals, current therapies are not that effective.

☆ Small ears, frizzy hair and dry ear wax - the genetics of mammoths
▼ + stars: | 2023-04-07 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

Researchers on Friday said they had analyzed the genomes of 23 woolly mammoths - including 16 newly sequenced ones - based on remains preserved in Siberian permafrost. "We find that woolly mammoths had molecular adaptations in genes related to coping with cold Arctic environments, such as thick fur, fat storage and metabolism, and thermal sensation, among others," Díez-del-Molino added. Woolly mammoths were about the size of modern African elephants, around 13 feet (4 meters) tall, but had much smaller ears to guard against losing body heat from a larger ear surface. One of them in humans is associated with Uncombable Hair Syndrome, a condition characterized by dry and frizzy hair that cannot be combed flat. The study helped clarify variable shades of mammoth hair color - brownish with a touch of red.

April 6 (Reuters) - The U.S. Supreme Court on Thursday refused to let West Virginia enforce a state law banning transgender athletes from female sports teams at public schools, one of many Republican-backed measures across the country targeting LGBTQ rights. The justices denied West Virginia's request to lift an injunction against the law that a lower court had imposed while litigation continues over its legality in a challenge brought by a 12-year-old transgender girl, Becky Pepper-Jackson. West Virginia said in a court filing that it can lawfully assign athletic teams by sex rather than gender identity "where biological differences between males and females are the very reason those separate teams exist." Pepper-Jackson, who attends a middle school in the West Virginia city of Bridgeport, sued after being prohibited from trying out for the girls' cross-country and track teams. Reporting by Andrew Chung in New York; editing by Jonathan Oatis and Sandra MalerOur Standards: The Thomson Reuters Trust Principles.

☆ This biotech can gain 50% thanks to interest in long-read sequencing technology, TD Cowen says
▼ + stars: | 2023-03-31 | by ( Sarah Min | ) www.cnbc.com time to read: +2 min

It's time to take another look at Pacific Biosciences of California as its growth story turns positive, according to TD Cowen. "Our bullish customer survey reflects upside to placements and pull through, along with a material budget shift to long reads. Pacific Biosciences shares are up more than 19% this year through Thursday, gaining after a rough couple of calendar years. However, Brennan's $15 price target, up from a prior $13, means shares can rise another 53% from Thursday's closing price. Central to the upgrade is the Revio system, a product from Pacific Biosciences that was launched last year and is designed to sequence whole human genomes.

☆ Locks of hair compose a symphony of genetic information on Beethoven
▼ + stars: | 2023-03-22 | by ( Will Dunham | ) www.reuters.com time to read: +4 min

Researchers said on Wednesday his genome showed the German composer was both genetically predisposed to liver disease and had hepatitis B virus infection. The new findings suggest there were multiple factors behind his liver disease including genetics, viral infection and alcohol consumption. "Prior to this study, alcohol was the only definitely known risk factor for Beethoven's liver disease." Beethoven experienced progressive hearing loss starting at age 29 and by 44 his hearing loss was complete, though he continued to compose masterpieces. There was no evidence found for conditions hypothesized by some experts such as otosclerosis or Paget's disease, Begg said.

☆ China's pig farms battle new surge in African swine fever
▼ + stars: | 2023-03-15 | by ( Dominique Patton | ) www.reuters.com time to read: +4 min

"Data from swine fever virus testing companies show that the number of positive detections exploded after the new year holiday. "We guess that the current swine fever infection area in northern production areas may be reaching 50%," it added. We feel it hasn't ended yet, that's the problem," he said, declining to be identified due to the sensitivity of disease outbreaks in China. HARD TO ASSESSChinese farms typically do not report disease outbreaks to the government, making it challenging to get an accurate picture of the extent of the infections. Though not as serious as in 2019, the disease could reduce production by more than 10%, Huachuang analyst Xiao Lin told Reuters.

☆ How GSK plans to replenish its depleted medicine cabinet
▼ + stars: | 2023-03-15 | by ( Maggie Fick | ) www.reuters.com time to read: +6 min

GSK has since suffered a series of clinical trial setbacks in its cancer drugs portfolio, most recently last year involving ovarian cancer drug Zejula and blood cancer drug Blenrep. BLOCKBUSTER POTENTIALAnalysts say that despite a string of strong quarterly earnings, lingering concerns over the company's drug pipeline reflect in GSK's share price. The investor said he does not see enough GSK drugs, either on the market or in development, with potential to be a so-called "blockbusters" with annual sales exceeding $1 billion. But Wood said the overhauled R&D department has put GSK in a strong position to meet growth targets. U.S. regulatory approval on GSK's vaccine, and a rival vaccine developed by Pfizer, is expected in May.

☆ Argentina makes headway in establishing a cannabis export industry
▼ + stars: | 2023-03-08 | by ( ) www.reuters.com time to read: +3 min

"The industry has incredible potential," said Gabriel Gimenez, director of the ARICCAME cannabis agency created in January this year, last week. Argentina is looking to build its domestic medical cannabis market and generate foreign currency through exports. In Santa Fe province, the medical cannabis research and development center (CIDCam), which has over 200 cannabis plants of various varieties, is expecting a second harvest this month. Pablo Fazio, president of the Argentine Chamber of Cannabis (ARGENCANN) and Pampa Hemp's co-founder, said demand could ignite a new domestic industry for products made from the raw material. The chamber comprises some 200 private firms either directly or indirectly linked to the industrial hemp and medical cannabis business.

☆ China opposes U.S. adding Chinese firms to trade blacklist
▼ + stars: | 2023-03-03 | by ( ) www.reuters.com time to read: 1 min

HONG KONG, March 3 (Reuters) - China opposes the United States adding several Chinese firms to its trade blacklist, China's commerce ministry said on Friday. China urges the United States to stop using any excuse to suppress Chinese firms, the ministry said in a statement posted on its website. The U.S. Commerce Department, which oversees export controls, recently added two units of genetics company BGI (300676.SZ) to the export control list. Reporting by Meg Shen and Twinnie SiuOur Standards: The Thomson Reuters Trust Principles.

☆ US blacklisting is no match for TikTok virality
▼ + stars: | 2023-03-03 | by ( ) www.reuters.com time to read: +2 min

NEW YORK, March 3 (Reuters Breakingviews) - The United States’ web of trade restrictions has a TikTok-sized hole in it. The Commerce Department added another 28 Chinese firms to its trade blacklist on Thursday, requiring licenses to acquire U.S. wares. Yet social media app TikTok, which government officials have repeatedly voiced national security concerns over, hasn’t been hit with trade curbs. TikTok parent ByteDance is based in China and has eluded that list, largely because the Commerce Department’s tools affect hard goods, not software. Meanwhile, negotiations between U.S. regulators and TikTok over a security deal have dragged on for years.

GMO wheat has never been grown for commercial purposes due to consumer fears about allergens or toxicities in the staple crop used worldwide for bread, pasta and pastries. The association was against adopting GMO wheat previously, but changed its stance after a survey it commissioned showed more than 70% of Brazilians would not mind consuming products containing it. Bioceres has said its GMO wheat "showed higher yields than conventional varieties across all environments, with an average 43% yield improvement in targeted environments." In November 2021, Brazil became the first country in the world to allow imports of flour made with GM wheat. "The approval for planting, imports and commercialization of GMO wheat resolves this issue, bringing peace of mind to different market actors," Abitrigo said in a statement.

Atlanta/Hong Kong CNN —The United States on Thursday added two subsidiaries of Chinese genetics company BGI to a trade blacklist over allegations it conducted genetic analysis and surveillance activities for Beijing, which Washington says was used to repress ethnic minorities in China. CNN has reached out to BGI Group, which is one of the world’s largest genomics companies and a listed firm based in Shenzhen, for comment on its subsidiaries. China has regularly pushed back against these reports with firm denials. The latest list compiled by the US Department of Commerce includes a total of 28 Chinese entities, four from Pakistan, three from Myanmar and one each from Belarus, Russia and Taiwan. Being placed on the list means the entities are restricted from buying American technology and other goods.

REUTERS/Eric ThayerMarch 2 (Reuters) - The Biden administration on Thursday added 37 companies to a trade blacklist, including units of Chinese genetics company BGI (300676.SZ) and Chinese cloud computing firm Inspur, in a move that promises to further ratchet up tensions with Beijing. The Commerce Department, which oversees export controls, added BGI Research and BGI Tech Solutions (Hongkong), over allegations that the units pose a "significant risk" to contributing to Chinese government surveillance. The Commerce Department accused Inspur of acquiring and attempting to acquire U.S. goods to support China's military modernization efforts. Commerce added 26 other Chinese entities to the list - which makes it hard for targeted companies to receive shipments of U.S. goods from suppliers. In 2020, the Commerce Department added two units of BGI Group, the world’s largest genomics company, to its economic blacklist over allegations it conducted genetic analyses used to further the repression of China’s minority Uyghurs.

☆ Qiagen partners with Sophia Genetics on next-generation sequencing kits
▼ + stars: | 2023-03-01 | by ( ) www.reuters.com time to read: 1 min

March 1 (Reuters) - Qiagen (QIA.DE) is to collaborate with Sophia Genetics (SOPH.O) on its next-generation sequencing (NGS) kits, the US-German pharmaceutical company said on Wednesday. The alliance, part of Qiagen's Qiqseq platform partnership program, aims to increase the compatibility of its NGS kits with third-party digital data-sharing and analytics companies. "The partnership with Sophia Genetics is planned to be expanded to other areas of analysis," it added. Reporting by Tristan Chabba in Gdansk Editing by Miranda MurrayOur Standards: The Thomson Reuters Trust Principles.

Takeda CFO Costa Saroukos in a 2018 picture. Mr. Saroukos joined Takeda in 2015 as CFO of Takeda’s European and Canadian operations before he was elevated to global CFO in 2018. WSJ: What did you learn from your deal-integration experiences that helped with the Takeda and Shire integration? ” — Costa Saroukos, CFO of TakedaAnother reason speed is important is to avoid losing talent. We broadened CFOinUrpocket to be used globally across 80 countries for the combined Takeda and Shire offices.

☆ Genetics study lays bare Ice Age drama for humans in Europe
▼ + stars: | 2023-03-01 | by ( Will Dunham | ) www.reuters.com time to read: +5 min

Tom Bjoerklund/Handout via REUTERSMarch 1 (Reuters) - Europe was no balmy paradise during the Ice Age, with the vast glaciers that blanketed large parts of the continent rendering wide swathes inhospitable for humans. While some populations hunkered down and survived in relatively warmer parts of Europe, including France, Spain and Portugal, others died out on the Italian peninsula, the study showed. "It refreshes our knowledge of how human beings survived the Ice Age," added paleogeneticist and study co-author He Yu of Peking University in China. Homo sapiens arose roughly 300,000 years ago in Africa, then spread worldwide, reaching Europe at least 45,000 years ago. The only people who survived this harshest period in Europe were hunter-gatherers who had found refuge in portions of France and the Iberian peninsula, the study found.

☆ How an AI breakthrough from Alphabet's DeepMind 'changed scientific history' and could lead to new cures
▼ + stars: | 2023-02-28 | by ( Andrew Dunn | ) www.businessinsider.com time to read: +11 min

"AlphaFold has sparked a wave of innovation by showing people what's possible," said Chris Bahl, the chief scientist at AI Proteins, a Boston startup using AlphaFold to help develop drugs. "AlphaFold, amazing as it, is just the beginning," Demis Hassabis, the CEO of DeepMind, said on a podcast last year. AlphaFold2 was built with far more biological and physics knowledge of proteins, Jumper said. Next uses will be 'progressively harder' as DeepMind stays secretive on its future workJohn Jumper, a senior staff research scientist at DeepMind who helped develop AlphaFold. "But AI will also continue to progress rapidly, and the folks at DeepMind are very good, so I'm optimistic."

☆ These 5 health conditions affect the Black community at higher rates—here are early signs to look out for and preventative measures
▼ + stars: | 2023-02-17 | by ( Renée Onque | ) www.cnbc.com time to read: +2 min

Health conditions like colon cancer and cardiovascular diseases impact people within the Black community at much higher rates than most other racial backgrounds, according to the Centers for Disease Control and Prevention. And even after the onset of life-threatening conditions, systemic issues lead to health disparities that prevent many Black people from accessing the resources they need. Human immunodeficiency virus (HIV): "In 2019, Blacks/African Americans represented 13% of the U.S. population, but 40% of people with HIV," says HIV.gov. Metabolic syndrome: Between 1988 and 2012, "Non-Hispanic black women were more likely than non-Hispanic white women to have metabolic syndrome," CDC data shows. Colon cancer: In 2016, Black men had the highest incidence and mortality rates of colorectal cancer, when compared to other racial groups, per CDC data.

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