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London CNN —Weight loss drugs such as Wegovy and Ozempic have been hailed worldwide as revolutionary for medicine. Additional measures to prevent obesity in the first place are desperately needed, health experts say. Part of that new thinking is exploring weight loss drugs. The OHA has crunched the numbers on existing weight loss drugs like Wegovy, the brand name for the appetite suppressant semaglutide. “There is no such thing as a silver bullet for obesity,” the Obesity Health Alliance emphasized.
Persons: Wes Streeting, Streeting, Eli Lilly, It’s, Keir Starmer, , Alfred Slade, suppressant, ” Slade, , it’s, Tom Little, prioritization, Jack Doughty, Martin White, ” White, White Organizations: London CNN, National Health Service, The Telegraph, Survey, British, Obesity Health Alliance, OHA, CNN, Reuters, Diabetes UK, NHS, of Health, Social Care, University of Cambridge Locations: United Kingdom, England, Novo Nordisk's, Denmark, sodas
The 22-year-old content creator approached her doctor about weight loss medication in March, before she had breast reduction surgery. Method: Zepbound, diet changes, exerciseZepbound, diet changes, exercise Duration: Took Zepbound from May to October. “The breast reduction was a big step, but the weight loss put a little cherry on top,” she said. Method: Compounded semaglutide, diet changes, exerciseCompounded semaglutide, diet changes, exercise Duration: Took compounded semaglutide from February to May. Method: Ozempic, diet changes, exerciseOzempic, diet changes, exercise Duration: Took Ozempic from May 2020 to October 2023“I was very close to being 300 pounds.
Persons: Sanjay Gupta, , Eduardo Grunvald, Alexus Murphy, CNN Alexus Murphy, Alexus, Murphy, It’s, it’s, , ” Murphy, Alexus Murphy She’s, “ It’s, “ I’m, you’re, Steven Ray, Ray, he’s, ” Ray, Becky Bell, CNN Becky Bell, she’s, Bell, ” “, ” Ozempic, Max Nazaire, ” Bell, Nazaire, She’s, Ozempic, Dustin Gee, CNN Dustin Gee, didn’t, I’ve, , ” Gee, Gee, , Cristian, Emanuel, Jackson, Alex, Gee's, Dr, CNN’s Tal Yellin Organizations: CNN, CNN — Research, University of California, BMI, Houston, Inland, Health, Medi, Cal, US Food and Drug Administration, FDA, , Bell, Ozempic, Mayo Clinic Diet, Get CNN, CNN Health Locations: San Diego, California, Houston, Woodstock , Georgia, Safe Haven, Peru, Bellingham , Massachusetts, Lima
"Forthcoming medications take the blockbuster GLP-1 medications and up the ante." Like semaglutide (the active ingredient in Ozempic and Wegovy), it works on GLP-1, a hormone that regulates blood sugar and appetite. CagriSema adds it to the already-popular drug semaglutide, which itself helps manage hunger and blood sugar levels. "Longer-acting versions of GLP-1 medications offer the potential for greater convenience and potentially improved adherence and sustained use over time," McGowan said. Timeline: Data from Phase II trials is expected later this year, and planning is underway for Phase III trials.
Persons: Eli Lilly, Dr, Christopher McGowan, Eli Lilly's, Ozempic, retatrutide, VK2735, we've, they're, McGowan Organizations: Pharma, Novo Nordisk, Viking Therapeutics, Triple, Therapeutics, FDA, orforglipron, Nordisk, Reuters Locations: GLP, Mounjaro, California
The blockbuster drugs Ozempic and Wegovy may help people cut back on drinking, new research published Wednesday in JAMA Psychiatry suggests. Just over 28 million adults in the U.S. have alcohol addiction, according to the National Institute on Alcohol Abuse and Alcoholism. Several other studies have examined drinking habits among people taking GLP-1 drugs who do not have alcohol use disorder. Around 75,000 people in the study used some type of medication to treat alcohol use disorder. So far, the clearest results have come from studies on alcohol addiction — but there is still a lot to understand.
Persons: Ozempic, , Alex DiFeliceantonio, Markku, , ” DiFeliceantonio, Christian Hendershot, Hendershot, Lähteenvuo, DiFeliceantonio, ” Hendershot Organizations: Psychiatry, National Institute, Alcohol, Biomedical Research Institute, Niuvanniemi Hospital, University of Southern California Institute for Addiction Science Locations: Sweden, U.S, Virginia, Finland, Swedish
Al Roker, 70, says he won't judge people who use Ozempic and other medications for weight loss. I think everybody's journey is their journey," Roker told The Daily Mail. AdvertisementAl Roker, 70, says he doesn't want to judge anyone who uses Ozempic for weight loss. I think everybody's journey is their journey," Roker said. Roker has been open about his struggles with binge eating and his dramatic weight loss journey through the years.
Persons: Al Roker, Roker, , you've, Ozempic, he's, everybody's, they've, Kelly Clarkson, Whoopi Goldberg, Clarkson, Elon Musk, Whoopi Goldberg —, Brianna Paruolo, Paruolo Organizations: Daily Mail, Service, Elon, FDA, Business Locations: New York
She's relieved to have gone from a 6X to a 1X — but worried about excess skin and her body image. download the app Email address Sign up By clicking “Sign Up”, you accept our Terms of Service and Privacy Policy . A sign on the wall at the weight management clinic inspires me every time I go for my body composite exam. The main reason I lost that initial weight was dental work. I often feel like I haven't lost much weight at all.
Persons: Betsy Smith, She's, , It's, I've, I'd, Smith, Toby, Steph, I'm Organizations: Service, Business Locations: Billings , Montana
Editor’s Note: CNN’s 5 Things newsletter is your one-stop shop for the latest headlines and fascinating stories to start and end your busy day. The day after a high-stakes presidential election usually brings elation on one side and dejection for the other. Now’s the time to take a breather and practice a little self-care. Today, the suburban New York dad has dedicated his life — and developed a video game — to help save other young people from overdoses. 3️⃣ Poignant postcard: In 1912, a first-class passenger on the Titanic scrawled a message in pencil to someone back home in England.
Persons: ake, ike, rance, riends, tim, Tod, Coll, egon, Georg, Richard Locations: ife, nsw, Ohio
People who lost a significant amount of weight with semaglutide saw major improvements in osteoarthritis knee pain, research published Wednesday in the New England Journal of Medicine finds. “Any sort of dramatic weight loss will relieve pain,” Bliddal said. In another study led by Bliddal, people with knee osteoarthritis were given an older weight loss drug, liraglutide. The average BMI in that study was about 32, lower than the average in the new study. Most of the people in the study had a BMI over 35, and nearly half had a BMI of over 40.
Persons: semaglutide, Wegovy —, , Daniel Wiznia, Henning Bliddal, David Felson, That’s, ” Wiznia, ” Bliddal, Bliddal, liraglutide, Felson, Wiznia, , ” Felson Organizations: New England, of Medicine, Novo Nordisk, Yale Medicine, University of Copenhagen, Boston University Chobanian, Avedisian School of Medicine, BMI, Food and Drug Administration Locations: Denmark
Packages containing syringes of the medications Wegovy, Ozempic and Mounjaro at a shop in Mitte, Germany, July 11, 2024. Several doses of semaglutide, the active ingredient in Wegovy and Ozempic, have been on the FDA's shortage list since early 2022. In a statement, Novo Nordisk said all doses of Wegovy and Ozempic are being shipped regularly to wholesalers. Still, Novo Nordisk said patients may not always be able to immediately fill their prescriptions at a particular pharmacy, even when a medication is listed as available. "Our intentional approach to gradually increase supply into the U.S. market is working," Novo Nordisk said.
Persons: Danish drugmaker, Eli Lilly, compounders Organizations: Novo Nordisk, U.S . Food, Nordisk, FDA Locations: Mitte, Germany, U.S, Danish, Novo
The report was messy, but it doesn't dim Eli Lilly's bright multiyear outlook, rendering the dip in the stock as a chance to buy. LLY .SPX 5Y mountain Eli Lilly's five-year stock performance compared with the S & P 500. Bottom line We're upgrading Eli Lilly to our buy-equivalent 1 rating and leaving our price target of $1,000 a share unchanged. Eli Lilly Why we own it: Eli Lilly's best-in-class drugs should enable growth above the industry average for many years to come. Eli Lilly's new Alzheimer's drug Kisunla, which was approved by the FDA in July, was not a major focus on the call.
Persons: Eli Lilly, Eli, Eli Lilly's, Jim Cramer, Jim, , that's, David Ricks, Ricks, Semaglutide, Wegovy, Lilly, There's, Mounjaro, Trulicity, Verzenio, Jim Cramer's, Cristina Arias Organizations: Revenue, The Club, CNBC, JPMorgan, Novo Nordisk, Food, Novo Nordisk's, FDA, Zepbound, Biogen, Merck, Pfizer, Morphic, Company, Pharmaceutical Locations: Tuesday's, U.S, Novo, Eisai, FactSet, Zepbound, Alcobendas, Madrid, Spain
➡️ In a CNN town hall, Harris called Trump a “fascist” and said he suggested he is unfit for office. Earlier in the day, she blasted Trump’s reported praise of Hitler. ➡️ The Harris campaign says it’s preparing for a deluge of litigation before and after Election Day. ➡️ Seven maps show how Trump, Harris and their running mates are dividing their time in critical swing states. ➡️ Trump’s reported racist insult about a slain Mexican American soldier has drawn backlash and staunch denials.
Persons: Donald Trump isn’t, McDonald’s, Trump, Harris, Donald Trump, Kamala Harris, they’ve, , Tim Walz, ➡️ Harris, Trump’s, Hitler, ➡️, Hillary Clinton, Elon Musk’s, ➡️ Trump’s, ➡️ Trump, Boeing machinists, machinists, Helene, Peter O’Leary, O’Leary, Robert Card, George Frey, Gaza Mahmoud Issa, Chantal Da Silva, Elizabeth Robinson Organizations: Boeing, NBC, Israel, CNN, Steelers, Trump, State, DOJ, GOP, CDC, NBC News, FEMA, Semaglutide, PBS, Anadolu, Getty, United Nations, NBC News ’, Atlas Coffee Locations: Traverse City , Michigan, Detroit, New York, Pittsburgh, Mexican, Colorado, Here’s, U.S, North Carolina, Chimney Rock , North Carolina, Pennsylvania, Lewiston , Maine, Wyoming, Jackson , Wyoming, Georgia, Gaza
Semaglutide, the active ingredient in Ozempic and Wegovy, appeared to reduce the risk of Alzheimer’s disease in people with Type 2 diabetes, according to a study published Thursday in the journal Alzheimer’s & Dementia. Another study, published in August, found that semaglutide appeared to cut the risk of dementia in people with Type 2 diabetes. Type 2 diabetes is a risk factor for dementia and Alzheimer’s. The study found that patients prescribed semaglutide had a significantly lower risk for Alzheimer’s disease than those who had taken one of the seven other diabetes drugs. The biggest difference was seen when comparing patients who took semaglutide to those who took insulin: Semaglutide patients had a 70% lower risk of Alzheimer’s, the study found.
Persons: , semaglutide, , Stephen Salloway, ” Salloway, Rong Xu, liraglutide, Xu, ” Xu, they’re, Salloway, they’ve, Donna Wilcock, there’s, ” Wilcock, Dr, Alberto Espay, Espay, What’s, , ” Espay Organizations: Alzheimer’s Association, Conference, Novo Nordisk, Warren Alpert Medical, Brown University, Center, Artificial Intelligence, Case Western Reserve University School of Medicine, Drug Administration, , Alzheimer’s, Indiana University School of Medicine, University of Cincinnati College of Medicine Locations: Novo, Rhode Island, Ohio
Novo Nordisk 's blockbuster diabetes drug Ozempic may reduce the risk of developing Alzheimer's disease, suggesting its potential to delay or prevent the memory-robbing condition, according to a study released Thursday. Alzheimer's disease is often diagnosed in the mild dementia stage, when a person has significant trouble with memory and thinking. But the number of Alzheimer's patients is projected to rise to almost 13 million in the U.S. by 2050. Novo Nordisk, which did not fund the new Case Western study, is also examining semaglutide in a late-stage study on Alzheimer's patients. In the liraglutide research, data from a midstage trial found that the drug may slow the progression of Alzheimer's disease by protecting patients' brains.
Persons: Semaglutide, Dr, Rong Xu, it's, Xu, Eli Lilly, Wegovy, Eli Lilly's Organizations: Novo Nordisk, Alzheimer's Association, Case Western Reserve University, CNBC, Nordisk, Case, National Institutes of Health, GLP Locations: U.S, Novo
Boxes of Ozempic and Wegovy made by Novo Nordisk are seen at a pharmacy. The FDA still has to make a final decision on whether to bar compounded versions of semaglutide, the active ingredient in Ozempic and Wegovy. In a statement, the agency said it is reviewing the petition and will respond directly to Novo Nordisk. The active ingredient in Wegovy and Ozempic, semaglutide, has been in intermittent shortages over the past two years. Like Novo Nordisk, Eli Lilly has sued several weight loss clinics, medical spas and compounding pharmacies across the U.S. over the past year.
Persons: Wegovy, Danish drugmaker, semaglutide, Eli Lilly, Eli Lilly's, compounders Organizations: Novo Nordisk, Tuesday, Food and Drug Administration, FDA, Nordisk Locations: Novo, Danish, U.S
The FDA’s announcement on Oct. 2 declaring the shortage over meant that compounding pharmacists had to stop filling tirzepatide prescriptions. Simone Williams, 50, of Spartanburg, S.C was prescribed compounded tirzepatide in June 2023 after her Mounjaro savings card expired. Williams began taking compounded tirzepatide for weight loss last year after her Mounjaro savings card expired. Tirzepatide was on the FDA’s drug shortage list for nearly two years. ‘Peace of mind’Meanwhile, patients and compounding pharmacists are celebrating the FDA decision to allow tirzepatide compounding to continue.
Persons: Lilly’s, Mounjaro, Zepbound, semaglutide, Wegovy, drugmakers, tirzepatide, , Simone Williams, S.C, Simone Williams Simone Williams, Williams, ” Williams, she’s, I’m, , Lilly, Michael Ganio, Ganio, Dr, Christopher McGowan, ” McGowan, ” Lilly, Jared Shapiro, ’ ” Shapiro, Elizabeth Kenly, ” Kenly, Kenly Organizations: Drug Administration, FDA, Association, American Society of Health, System, Outsourcing, Alliance, Pharmacy, APC Locations: Spartanburg, Spartanburg , South Carolina, U.S, Cary , North Carolina, Graham , North Carolina
New York CNN —Price distortions and dysfunction are nothing new in the $73 billion wedding industry. For better or worse, many brides are using the drugs ahead of their big day, lured in by the promise of rapid weight loss. The right fitThe ideal time to buy a wedding dress is eight to 10 months before the event, according to wedding planning site the Knot, and some planners recommend buying a full year in advance in case of shipping delays. “Usually, the dress was ordered somewhere in the middle of those 50 pounds.”It’s hard to overstate how such drastic weight loss can complicate a wedding dress’ fit. “Weight loss has always been a top of priority.
Persons: CNN Business ’, Tami Luhby, Susan Ruddie, Dresser, Spring, That’s, they’re, , Myrna Lundberg, , Lundberg, ” Lundberg, “ It’s, — it’s, you’re Organizations: CNN Business, New York CNN, FDA, Drug Administration, Bureau of Labor Statistics, CNN Locations: New York, China, Suez, United States
Jaap Arriens | NurPhotoDanish biotech Zealand Pharma is targeting the "next generation" of weight loss drugs as competitors pile into a market dominated by heavyweights Novo Nordisk and Eli Lilly . Last month, Zealand Pharma announced positive top-line results from a phase 1b trial of its weight-loss drug, a GLP-1/GLP-2 receptor dual agonist called Dapiglutide. Stock Chart Icon Stock chart icon Zealand Pharma. Novo Nordisk is also experimenting with its own version of the treatment, combining the GLP-1 component Semaglutide with amylin analog Cagrilintide in a candidate called CagriSema. Syringes from weight loss drugs "Wegovy," "Ozempic" and "Mounjaro."
Persons: Jaap Arriens, Eli Lilly, Adam Steensberg, Steensberg Organizations: Zealand Pharma, Novo Nordisk, CNBC, pharma, Nordisk, Union, Getty Locations: U.S
5 Nobel-worthy discoveries that haven’t won the prize
  + stars: | 2024-10-05 | by ( Katie Hunt | ) edition.cnn.com   time to read: +8 min
The first human genomeThe mapping of the human genome has had a huge impact on biology and other fields. The output from a DNA sequencer is shown in this undated image from the National Human Genome Research Institute. But one reason the project may not have earned a Nobel Prize is the sheer number of people involved in the feat. The Nobel Prize in physiology or medicine will be announced on Monday, followed by the physics prize on Tuesday and the Nobel Prize in chemistry on Wednesday. The Nobel Prize for literature will be announced on Thursday and the Nobel Peace Prize on Friday.
Persons: Alfred Nobel, Nobel, Carsten Snejbjerg, Svetlana Mojsov, Joel Habener, Lotte Bjerre Knudsen —, Lasker, Knudsen, Hassabis, John Jumper, Lester Cohen, David Pendlebury, Pendlebury, “ Nobel, David Baker, , Boris Roessler, We’re, Jeffrey Gordon, Robert J, Glaser, Louis, Gordon, Claire King, Barack Obama, Drew Angerer, Mary, King Organizations: CNN, Stockholm —, Human Genome Research, Nordisk, Bloomberg, Getty, Rockefeller University, Harvard Medical School, Novo Nordisk, Clarivate’s Institute for Scientific Information, Google, Institute for Protein, University of Washington School of Medicine, Washington University, of Locations: Swedish, United States, United Kingdom, France, Germany, Japan, China, Hillerød, Denmark, Los Angeles, St
In this article LLYNOVO.B-DK Follow your favorite stocks CREATE FREE ACCOUNTAn Eli Lilly & Co. Zepbound injection pen, March 28, 2024. Bills of lading, the digital receipts of freight containers, show that the delivery mechanisms for insulin and weight-loss drugs rely on East Coast ports for incoming trade. "Novo Nordisk and Eli Lilly are both heavily reliant on the Port of Norfolk," said William George, director of Research at ImportGenius, which tracks the customs data. Vials on the Wegovy line at the Novo Nordisk A/S production facilities in Hillerod, Denmark, on Friday, March 8, 2024. Bloomberg | Bloomberg | Getty ImagesAn Eli Lilly spokesperson said it does not discuss the details of its external supplier relationships.
Persons: Eli Lilly, Eli Lilly — Ozempic, William George, George, Dennis Monts Organizations: Bloomberg, Getty, Novo Nordisk, ILA, Nordisk, Research, U.S . Senate, CNBC, Nuco Logistics Locations: New England, Texas, U.S, lading, East Coast, Port of Norfolk, ImportGenius, Norfolk, airfreight, Hillerod, Denmark, Monts
James Corden said Ozempic didn't help him lose weight because he doesn't eat only when he's hungry. But Ozempic doesn't address the root cause of eating behaviors nor change them, experts say. "I tried Ozempic, and it won't be surprising to you when you look at me now, that it didn't really work," he said, per People. AdvertisementOzempic doesn't address the root cause of eating behaviors nor change themFor those who have a more complex relationship with food and maybe struggle with emotional eating, Ozempic might not be the answer. "Emotional eating is a complex behavior that often has little to do with physical hunger cues.
Persons: James Corden, Ozempic didn't, , who's, Brianna Paruolo, Paruolo, semaglutide, Sarah Boss, Boss, Stephen Powis, I'm Organizations: Service, National Health Service Locations: British, New York, England
The high price of weight-loss drugs is frustrating for patients who can't access them, a doctor said. Patients struggle to afford these drugs, leading to cycling, rationing, or using risky alternatives. AdvertisementPharmaceutical companies are facing a new wave of criticism for the high price of groundbreaking weight-loss drugs. The latest generation of these class of drugs, medications like Ozempic, Wegovy, Mounjaro, and Zepbound, are once-weekly injections. The competitive pressure will also help drive prices lower as companies aim to attract consumers back to their brand with cheaper options for weight-loss drugs.
Persons: , Dr, Christopher McGowan, McGowan, that's, they've, Ted Kyle, Kyle Organizations: Service, Pharmaceutical, FDA
A woman who had life-changing results on a popular weight loss drug struggled to afford it for years. AdvertisementTara Rothenhoefer, a 49-year-old Florida resident, says her life changed when she joined a clinical trial for a promising new weight-loss medication. While regulated, these compounded drugs aren't FDA-approved, raising concerns from doctors about variations in quality. The grey market of weight-loss drugs is vast and complicated. In August, Eli Lilly halved the price of its weight-loss drug Zepbound through single-dose vials — a bid to lure customers back to brand-name drugs, analysts said.
Persons: , Tara Rothenhoefer, Rothenhoefer, Eli Lilly, She's Organizations: Service, Novo Nordisk's, Research, FDA, Pharmaceutical Locations: Florida
A box of Ozempic made by Novo Nordisk is seen at a pharmacy in London, Britain March 8, 2024. Novo Nordisk 's blockbuster diabetes drug Ozempic may decrease the risk of opioid overdoses in certain patients, demonstrating its potential as an alternative treatment for opioid use disorder, according to a new study released Wednesday. The active ingredient in Ozempic, semaglutide, was associated with a "significantly lower" opioid overdose risk than other diabetes medications in people diagnosed with both Type 2 diabetes and opioid use disorder, said the paper published in JAMA Network Open. Around 3,000 people were prescribed semaglutide injections, while the remaining patients received treatments that ranged from insulins to older GLP-1s for diabetes. That reflects a 58% lower risk of opioid overdose in patients who took semaglutide, Xu said.
Persons: Dr, Rong Xu, Eli Lilly, Lilly's, Xu Organizations: Novo Nordisk, JAMA, Case Western Reserve University, Centers for Disease Control, National Center for Drug, U.S, National Institutes of Health, Novo Nordisk's Victoza Locations: London, Britain, Novo
The head of the committee, Sen. Bernie Sanders, I-Vt., has been vocal about his frustrations over how much Novo Nordisk charges Americans for both Ozempic (used to treat type 2 diabetes) and Wegovy (approved for weight loss). Mariam Zuhaib / AP“It is clear that Novo Nordisk is ripping off the American people,” Sanders told NBC News in June. In a statement Monday, Novo Nordisk defended its pricing structure. Novo Nordisk holds the patent on semaglutide, so other companies aren't able to make a generic version. That leaves Novo Nordisk — and ultimately Jørgensen — to answer questions about the price of its blockbuster drugs.
Persons: Lars Fruergaard Jørgensen, Jørgensen, Sen, Bernie Sanders, Sanders, Mariam Zuhaib, ” Sanders, , United States don’t, Organizations: Nordisk, Capitol, Health, Education, Labor, Pensions, NBC News, Novo Nordisk, Department of Health, Human Services, NBC, Novo Nordisk — Locations: Canada, Europe, United States, Germany, United Kingdom, U.S, Novo
Wegovy, the blockbuster weight loss treatment from Novo Nordisk , tops the list of drugs that could soon become part of the second round of price negotiations between manufacturers and Medicare. The Biden administration last month announced new negotiated prices for the first 10 Medicare Part D drugs selected for the talks. He also pushed back on Medicare price negotiations when asked about the potential selection of Wegovy and Ozempic, calling the talks "price-setting" that will have negative consequences for drug innovation. Medicare Part D doesn't cover weight loss treatments unless they are approved and prescribed for another health condition. We'll be following the next round of Medicare drug price negotiations closely, so stay tuned for our coverage.
Persons: Wegovy, Hollie Adams, Biden, it's, Novo, Lars Fruergaard Jørgensen, Lars Jorgensen, Ozempic, Piroschka Van De Wouw, Jørgensen, Semaglutide, We'll, Annika, annikakim.constantino Organizations: Novo Nordisk, Reuters, Specialty Pharmacy, Centers, Medicare, Medicaid Services, Health, Education, Labor, Capitol, CMS, Wall Street, GSK, Astellas Pharma, Epic Systems Locations: London, Britain, Novo, Washington , U.S
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