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☆ Period pain and depression: Study finds genetic connections
▼ + stars: | 2024-11-29 | by ( Kristen Rogers | ) edition.cnn.com time to read: +8 min

It uses genetic data … to see if having certain genes linked to depression also makes people more likely to have menstrual pain. The findings help expand the important, and often overlooked, discussion around mental health and period pain. Below, experts elaborate on newfound and known associations between period pain and depression, why a genetic cause can’t be inferred from a genetic connection, and ways you can manage depressive symptoms and painful periods. On the other hand, experts noted that the opposite relationship — period pain or reproductive shifts preceding depression — has occurred in both human and animal research and in clinical practice. Additionally, methods experts know to be effective in treating period pain can also improve depression, Amies Oelschlager said — such as exercise, yoga, stress-reduction techniques, dietary changes and good sleep quality and quantity.

Persons: —, ”, John Moraros, Moraros, ” Moraros, Anne, Marie Amies Oelschlager, wasn’t, Amies Oelschlager, Claudio Soares, Soares, dysmenorrhea, “, Hugh Taylor, Anita O’Keeffe Young, Taylor wasn’t, Taylor Organizations: CNN, School of Science, Jiaotong, Liverpool University, Psychiatric Genomics Consortium, University of Washington School of Medicine, Queen’s University School of Medicine, American College of Obstetricians, Yale School of Medicine Locations: China, Kingston , Ontario

☆ Who gets weight loss drugs covered by insurance? In North Carolina, being on Medicaid helps
▼ + stars: | 2024-11-28 | by ( Melba Newsome | Kff Health News | ) www.nbcnews.com time to read: +7 min

“This exceeds the amount the State Health Plan spends on cancer, rheumatoid arthritis, and chemotherapy medications,” the State Health Plan said in a March statement. The health plan’s board of trustees eliminated coverage of this class of medications for weight loss starting in April. “They know diets don’t work long-term for weight loss, yet they are denying coverage for a medication that has been effective,” Blanchard said. But patients typically need to stay on the medications to maintain their weight loss, meaning they face long-term costs. Besides making the medication more affordable, he said, it should encourage the use of weight loss drugs and treatment of obesity as a chronic disease instead of stigmatizing it as a moral failing.

Persons: Anita Blanchard, Charlotte, —, Blanchard, ”, “, Biden, ” Blanchard, Donald Trump, Ozempic, Nishant Shah, Kody Kinsley, doesn’t, ” Kinsley, Kinsley, “ We’re, Duke’s Shah, ” Shah, Melissa Jones, ‘, ’ ” Jones, Blanchard can’t Organizations: University of North, North Carolina, Health, State Health, West Virginia, Medicare, Services, Duke University, North Carolina Department of Health, Human Services, University of Chicago Locations: University of North Carolina, North Carolina, North, West, Connecticut, Carolina, U.S

Paduch, 57, was sentenced Wednesday to life in prison for sexually abusing the seven former patients between 2007 and 2022. via NBC New YorkSpokespeople for Weill Cornell and Northwell Health declined to answer specific questions related to Paduch, citing the ongoing litigation. But behind closed doors, Paduch preyed on the men and boys who sought him out. One of the men who filed a lawsuit against Paduch had medical training himself but said he still didn’t realize until many years later that it was abuse. ‘Shocking and embarrassing’By then, Weill Cornell had already received at least two complaints about Paduch from its own employees, going back more than a decade.

Persons: Weill Cornell, Paduch, ”, Mallory Allen, “, ” Allen, Darius Paduch, York Spokespeople, Azza, it’s, ‘, ’ Paduch, Thomas Giuffra, Weill Cornell —, Giuffra, urologists, Weill, Weill Cornell urologist, Harvey Weinstein, Paduch “, Maansi Srivastava, —, Paduch —, ” —, — “ Organizations: Weill, BR, NBC, York, Weill Cornell, Northwell, Health, Weill Cornell Medicine, Public Citizen, Medical Academy of Lodz, New, New York Health Department’s, Professional, NBC News, Health Department Locations: Seattle, Poland, Manhattan, New York

☆ Those typing monkeys will never produce Shakespeare’s works, mathematicians say
▼ + stars: | 2024-11-01 | by ( Amarachi Orie | ) edition.cnn.com time to read: +4 min

CNN —Talented though they may be, monkeys will never type out the complete works of William Shakespeare, or even a short book, a new study suggests. The Infinite Monkey Theorem is a famous thought experiment that states that a monkey pressing random keys on a typewriter would eventually reproduce the works of the Bard if given an infinite amount of time and/or if there were an infinite number of monkeys. However, in the study published in the peer-reviewed journal Franklin Open, two mathematicians from Australia’s University of Technology Sydney have rejected this theorem as “misleading” within the confines of our finite universe. They challenged it by looking at the Finite Monkeys Theorem, in which there is a finite amount of time and a finite number of monkeys. “By the time you’re at the scale of a full book, you’re billions of billions of times less likely,” he continued.

Persons: William Shakespeare, Bard, Stephen Woodcock, ”, Woodcock, Jay Falletta, George, ” Woodcock, Chris Banerji, Alan Turing, Banerji, ’ ”, Bard ‘ Organizations: CNN, Franklin, Australia’s University of Technology Sydney, University of Technology, Alan, “ Locations: University of Technology Sydney, London

☆ Nestlé and L'Oréal are betting on a longevity supplement made from pomegranate juice
▼ + stars: | 2024-10-25 | by ( Hilary Brueck | ) www.businessinsider.com time to read: +9 min

Urolithin A supplement company Timeline has investments from both Nestlé and L'Oréal. This year, the conversation quickly turned to the supplement du jour, the compound that has drawn investment from both Nestlé and L'Oréal: Urolithin A. Starting in 2008, Rinch's supplement company, Amazentis, funded over a dozen studies on urolithin A, including some relatively large, placebo-controlled trials in people — a rarity in supplement research. Urolithin A has also captured the attention of longevity researchers, who are typically more skeptical about products promising to make you young again. Timeline was on the agenda at this year's ARDD, an annual longevity research conference held in Copenhagen in August.

Persons: —, There's, Urolithin, Hilary Brueck, Chris Rinsch, Rinsch, Johan Auwerx, Amazentis, Auwerx, He's, Mark Hyman, Dave Asprey, Gwyneth Paltrow's, Will Cole, Dominic Denk, Denk, wouldn't, Timeline's, Andrea Maier, it's, Maier Organizations: Service, VC, Business, Frankfurt University Hospital, National University of Singapore Locations: Gstaad, Swiss, skincare, urolithin, Davos, Copenhagen, Germany, Switzerland, Nestlé

☆ Psilocybin: Searching for the antidepressant of the future
▼ + stars: | 2024-10-22 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +13 min

The stakes are high for psilocybin clinical trials — there’s a pressing need for a more effective medical solution in the fight against depression, especially treatment-resistant depression. “People begin to feel, understand and appreciate that their brain can change and they can escape from their depression,” Nutt said. “For that reason alone, this research matters.”At six weeks, the study found no significant difference in depression scores between the antidepressant and psilocybin groups. In fact, Madras said, adverse effects are such a concern that researchers in psychedelic clinical trials often actively recruit people who have successfully taken psychedelics in the past. In a study using psilocybin for alcohol substance abuse, for example, some 95% of those involved correctly guessed whether they were taking psilocybin or the placebo.

Persons: ”, Dr, Bertha Madras, “, Charles Raison, ’ “, don’t, David Nutt, ” Nutt, it’s, I’m, Timothy Leary, hasn’t, It’s, Harvard’s, Casey Wolfington, Katie Harmon, escitalopram, Nutt, Tommaso Barba, wasn’t Organizations: CNN, Harvard Medical, McLean Hospital, University of Wisconsin School of Medicine, Public Health, Vail Health Behavioral Health Innovation Center, Imperial College London’s, Food, FDA, Imperial College London Locations: United States, Belmont , Massachusetts, ” Madras, Madison, Vail, Colorado, Harvard’s Madras, Madras

☆ Eli Lilly to build $4.5 billion research and manufacturing center to propel drug pipeline
▼ + stars: | 2024-10-02 | by ( Angelica Peebles | In Angelicapeebles | ) www.cnbc.com time to read: +2 min

Eli Lilly will spend $4.5 billion to build a center aimed at finding better ways to manufacture its medicines. The facility, called the Lilly Medicine Foundry, will house development of new manufacturing methods with an eye toward efficiency. It's a strategy that's already paying off with Lilly's obesity and weight loss drugs Mounjaro and Zepbound, and Lilly wants it to propel the rest of its pipeline. Lilly says the facility will be the first of its kind to combine research and production in a single location. It will be near a $9 billion manufacturing complex Lilly is building in Lebanon, Indiana, to produce pharmaceutical ingredients like tirzepatide, the active ingredient in Mounjaro and Zepbound.

Persons: Eli Lilly, Mounjaro, Lilly, David Ricks, –, Dan Skovronsky Organizations: Lilly, Foundry, Indianapolis, Novo Nordisk's Ozempic Locations: Indianapolis, Lebanon , Indiana, tirzepatide

☆ Some baby boomers are burning through their retirement savings to pay for cancer treatments. Then they have to go back to work.
▼ + stars: | 2024-09-15 | by ( Juliana Kaplan | Noah Sheidlower | ) www.businessinsider.com time to read: +13 min

AdvertisementIt's a story all too familiar for some older Americans: An unexpected health crisis derails their retirement planning. With insufficient help from health insurance or Social Security, medical bills eat up any savings or income they have. Jones, who gets $2,200 a month in Social Security, has had to take on part-time work, which made her ineligible for some federal assistance. She paid for chemo out of pocket, spending her way through her retirement savings and maxing out her credit cards. Amend said it's crucial for older Americans to believe everything will be OK, noting "your mindset perpetuates what your outcome will be."

Persons: —, Kimberly Mullen, Mullen, She's, she'll, Nancy Altman, Saul Martinez, Karen Knudsen, they've, Uber, Wendy Jones, it's, she's, Jones, Teresa Ghilarducci, , Ghilarducci, Rebecca Buffum, Buffum, I'm, Andrew Whitaker, Marion, Robert Papalia, Papalia, Leonard Bianconi, Bianconi, Gallup, Monique Morrissey, haven't, Harris, Morrissey, Frank, Weeks, he's Organizations: Service, Business, Social Security, American Cancer Society, Social, Walmart, Medicare, New School for Social Research, Schwartz, for Economic, Kaiser Family Foundation, BI, Institute, Biden, American Heart Association Locations: Kentucky, North Carolina

Taking a high dose of ADHD drugs is linked to more than five times greater risk of developing psychosis or mania, according to a new study published Thursday in the American Journal of Psychiatry. The research is among the first to find a relationship between escalating doses of the drugs — amphetamines, in particular — and a greater likelihood of psychotic symptoms. The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The medium dosage — 20 mg to 40 mg of Adderall, 50 mg to 100 mg of Vyvanse or 15 mg to 30 mg of dextroamphetamine — was linked to a 3.5 times higher risk. There was no increased risk of psychosis with another ADHD drug, Ritalin, which isn’t an amphetamine.

Persons: it’s, ”, Jacob Ballon, hadn’t, Will Cronenwett, ” Cronenwett, Vyvanse, Takeda, Lauren Moran, Brigham, “, ” Moran, Moran, Cronenwett, ” Ballon, they’re Organizations: American, of Psychiatry, Stanford Medicine, Northwestern Medicine, Psychiatry, NBC News, Takeda Pharmaceuticals, . Food, Drug Administration, FDA, Pharmaceuticals, McLean Hospital, Mass Locations: United States, U.S, Boston

The findings bring the phenomenon — and the controversy — of the latest new and powerful weight loss drugs to the youngest age group yet. The new trial looked at liraglutide, the active ingredient used in two of Novo Nordisk’s older GLP-1 drugs: Saxenda, a weight loss drug, and Victoza, a diabetes drug. So instead of looking at overall weight loss like in adult studies, they decided to focus more on BMI, which takes into account both weight and height. A spokesperson for Novo Nordisk said that it has submitted an application to the Food and Drug Administration to expand the approval of liraglutide for weight loss in children ages 6 to 11. Is 6 too young for a weight loss drug?

Persons: Roy Kim, “, ” Kim, Claudia Fox, Fox, Eli Lilly, ”, liraglutide, ” Fox, Sarah Armstrong, ” Armstrong, comorbidities, it’s, ” Wegovy, Zepbound, Shauna Levy, ” Levy Organizations: New England, of Medicine, Novo Nordisk, Cleveland Clinic, Centers for Disease Control, University of Minnesota, BMI, Food and Drug Administration, American Academy of Pediatrics, Duke University, Tulane Bariatric Center Locations: liraglutide, Ozempic, Ohio, U.S, New Orleans

If approved, it would have been the first new treatment for PTSD in more than two decades. Lykos Therapeutics had asked the FDA to approve the drug as part of a treatment regimen, given alongside talk therapy. Lykos Therapeutics had asked the FDA to approve the drug as part of a treatment regimen, given alongside talk therapy. Lykos added that the agency expressed concerns similar to those raised during the advisory committee meeting in June. Davis Institute for Psychedelics and Neurotherapeutics, said he doesn’t think the FDA decision will hinder the development of psychedelics for mental health disorders, including PTSD.

Persons: “, ”, Holly Fernandez Lynch, Lykos, Amy Emerson, Sarah Silbiger, David Olson, Olson, ” Olson, Brian Barnett, ” Barnett, Joe Biden, Biden, Robert Califf, ” Lynch, psychedelics, David Rind Organizations: Drug Administration, Therapeutics, FDA, Lykos Therapeutics, University of Pennsylvania, Davis Institute for Psychedelics, Cleveland Clinic, Clinical Locations: U.S, White Oak, Md, Ohio

☆ Black people with Parkinson's are underdiagnosed, miss treatment
▼ + stars: | 2024-08-04 | by ( Elizabeth Cohen | Elizabeth Cohen Is A Contributor For Kff Health News. | ) www.nbcnews.com time to read: +6 min

A few years ago, the organizers of one of the largest U.S. exercise programs for people with Parkinson’s disease realized they had a problem: Most of the students were white. But people who run Parkinson’s exercise programs in a handful of U.S. cities describe great difficulty in recruiting Black people. Johnson said his Chicago-area initiative offered a free six-month exercise program for Parkinson’s patients and increased marketing in the Black community but got little traction. When a white person shows up at the doctor’s office with such symptoms, a doctor would likely recognize them as signs of Parkinson’s, said Bernard Coley, an advocate for people with Parkinson’s disease, especially those in underengaged communities. After his less-than-successful efforts to recruit Black Parkinson’s patients into his exercise program in Chicago, Johnson concluded that the fact that he’s not Black is an “important factor.”Leventhal, who runs the Parkinson’s exercise program in New York, has come to the same conclusion.

Persons: “ We’re, who’s, ”, David Leventhal, Mark Morris, New York City . Leventhal, Leventhal, it’s, ” Leventhal, Eddie Marritz, Parkinson’s —, Eric Johnson, Johnson, “, Bernard Coley, Coley, Amber Star Merkens, ” Coley, Wendy Lewis, Tammyjo, Black, he’s, puller Organizations: Mark Morris Dance Group, New York City ., Mark Morris Dance, Yale, Movement, Parkinson’s, Nature, Parkinson’s Foundation, Parkinson Council, Emory University, KFF Locations: U.S, New York City, Chicago, California, Philadelphia, Atlanta, New York

☆ The 'double bind' is a big mistake employers make that's turning off Gen Z staff
▼ + stars: | 2024-07-23 | by ( Lindsay Dodgson | ) www.businessinsider.com time to read: +5 min

They want diverse employers that offer a good work-life balance, remote positions, and solid mental health policies. AdvertisementThis, she said, is what's known as a "double bind," and it drives Zoomers mad. A double bind, Chang explained, is "when you are giving two or more contradicting messages at the same time." In the survey, Gen Zers were the most likely cohort to have been in a double bind (84%). Advertisement"People my age and up didn't talk about mental health," Chang said, which is why older generations can be a bit "put off" when a young employee asks for a mental health day.

Persons: —, Jeanie Y, Chang, We're, Dale Wilsher, Gregory Bateson, Wilsher, Gen Zers, Oliver Wyman, Zoomers, Zers Organizations: Service, Business, Forbes

☆ Why AI deals in healthcare have grown faster than other areas of tech — and what VCs are paying close attention to
▼ + stars: | 2024-06-11 | by ( Rebecca Torrence | ) www.businessinsider.com time to read: +8 min

Healthcare AI companies raised $2.8 billion in the first quarter of this year, according to the SVB report titled "The AI-powered Healthcare Experience." SVB projects funding to AI healthcare companies to total $11.1 billion in 2024. While healthcare AI startups might have it better, they're not out of the woods. Healthcare startups using AI for administrative tasks have grabbed $6.6 billion since 2021 and made up 42% of healthcare AI deals in the first quarter of this year, according to SVB. AdvertisementIn some cases, Big Tech companies are pushing healthcare startups forward.

Persons: —, Raysa Bousleiman, they're, Siva Namasivayam, Galym, Bousleiman, Shiv Rao Abridge, Lynne Chou O'Keefe, Lightspeed's Imanbayev Organizations: Service, Silicon Valley Bank, Business, Big Tech, Abridge, Health, Lightspeed Venture Partners, Google, Fathom, Nvidia, Ventures, Technologies Locations: Cohere, Abridge, SVB .

☆ Internet addiction may harm the teen brain, MRI study finds
▼ + stars: | 2024-06-04 | by ( Kristen Rogers | ) edition.cnn.com time to read: +8 min

A new study has possibly captured that objectively, finding that for teens diagnosed with internet addiction, signaling between brain regions important for controlling attention, working memory and more was disrupted. Specifically, internet ‘addiction,’ which was initially conjured up by (psychiatrist) Ivan K. Goldberg in 1995 as a joke. Das wasn’t involved in the study. “Overall, the mechanisms underlying internet addiction are more like an emerging pattern than a finished picture,” Chang said. “Similar to substance and gambling disorders, internet addiction rewires the brain, making it harder to resist internet related stimuli,” he added.

Persons: ”, Max Chang, ” Dr, David Ellis, Ellis, wasn’t, Ivan K, Goldberg, ’, ” Ellis, isn’t, Eva Telzer, ” Telzer, Smita Das, Das wasn’t, Caglar, Yildirim wasn’t, ” Chang, Chang, Yildirim, Das, ” Das, “ Organizations: CNN — Teens, Mental Health, Brigade, Family Service, University of Bath’s Institute for Digital Security, Disorders, University of North, Chapel Hill, Stanford Medicine, Khoury College of Computer Sciences, Northeastern University, American Psychiatric Association, APA Locations: San Francisco, United States, Asia, China, University of North Carolina, Chapel, California, Boston, APA’s

CNN —A 62-year-old man has died months after becoming the world’s first living recipient of a genetically edited pig kidney transplant, hailed as a medical milestone. Rick Slayman received the kidney at Massachusetts General in March after he had been diagnosed with end-stage kidney disease last year. “Our family is deeply saddened about the sudden passing of our beloved Rick but take great comfort knowing he inspired so many,” a family statement said. Before Slayman’s transplant, just two transplants using pig organs had been completed – both heart transplants performed under compassionate use. EGenesis, the biotech company providing the genetically edited pig kidney, called Slayman “a true pioneer” in a statement late Saturday night.

Persons: Rick Slayman, Mr, Slayman, Slayman’s, ”, “, Rick, –, ” Slayman, Tatsuo Kawai Organizations: CNN, Massachusetts General, Massachusetts Department of Transportation, Legorreta, Procurement, Transplantation Network, Massachusetts Locations: Massachusetts, ” Massachusetts

☆ Genes known to increase the risk of Alzheimer’s may actually be an inherited form of the disorder, researchers say
▼ + stars: | 2024-05-06 | by ( Brenda Goodman | ) edition.cnn.com time to read: +10 min

Among people diagnosed with Alzheimer’s, researchers recognize familial forms of the disease and sporadic cases. This shifting appreciation of inherited risk, researchers say, is due to a better understanding of the role of a fourth gene that carries the blueprints to make a lipid-carrying protein called apolipoprotein E, known as APOE. One known as APOE2 is thought to be protective against the development of Alzheimer’s disease. They also compared people with two copies of APOE4 to people with other inherited forms of the disease — early-onset autosomal dominant Alzheimer’s disease (ADAD) and Down syndrome-associated Alzheimer’s disease (DSAD). Gene testing isn’t currently recommendedIt is also likely to change how people who carry the APOE4 gene are diagnosed and treated.

Persons: APOE4, ”, Dr, Juan Fortea, Sant, Fortea, Charles Bernick, Bernick, Alzheimer’s wasn’t, isn’t, they’re, ” Fortea, Sanjay Gupta, Reisa Sperling, “, ” Sperling, ” Dr, Sterling Johnson, Johnson Organizations: CNN, Nature, National Alzheimer’s Coordinating, Neurology, Hospital de, Cleveland Clinic Lou, Brain Health, CNN Health, Alzheimer’s Research, Brigham, Women’s, Alzheimer’s, University of Wisconsin Locations: Alzheimer’s, Spain, United States, Santa, Barcelona, Wisconsin

☆ This biotech stock specializing in targeted cancer treatments can surge 50%, Jefferies says
▼ + stars: | 2024-04-17 | by ( Pia Singh | ) www.cnbc.com time to read: +2 min

Nuvalent could be a winning biotech in the world of cancer treatments, according to Jefferies. Analyst Roger Song initiated the clinical-stage biopharmaceutical company with a buy rating and $97 price target, which implies 49.8% potential upside for shares over the next 12 months. "NUVL leverages strong expertise in structure-based chemistry and deep understanding of unmet [patient] needs to develop potentially 'best-in-class' small molecule targeted cancer therapy," Song wrote in a Wednesday note. "We think both candidates poise well in later line and have strong potential to move into frontline treatments." The company posted a fourth-quarter loss that was slightly wider than expected, at 62 cents per share.

Persons: Roger Song, Jefferies Organizations: Jefferies, U.S . Food, Drug Administration, FactSet Locations: U.S

☆ Qureight uses AI to help speed up drug development. Check out the 11-slide pitch deck it used to raise $8.5 million.
▼ + stars: | 2024-04-16 | by ( Riddhi Kanetkar | ) www.businessinsider.com time to read: +2 min

British techbio startup Qureight has secured $8.5 million in an oversubscribed Series A round. Launched in 2018, Qureight wants to simplify how pharma companies deal with the complex datasets often used during clinical trials. "For example, we can start to structure images of lungs using AI," said cofounder and CEO Muhunthan Thillai. The startup primarily works with pharmaceutical companies, including heavyweights such as AstraZeneca, as well as hospitals and clinical research organizations. Check out the 11-slide pitch deck used to secure the fresh funding.

Persons: Qureight, Muhunthan Thillai, Thillai, Hargreave Hale Organizations: pharma, Business, AstraZeneca, Hargreave Hale AIM VCT, XTX Ventures, Guinness Ventures, Playfair, Fund, Cambridge Angels Locations: Cambridge, Meltwind

☆ Pregnancy complications linked to increased risk of early death even decades later, study finds
▼ + stars: | 2024-04-15 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +8 min

CNN —Pregnancy complications, such as gestational diabetes or preeclampsia, may be linked to an elevated risk of death even decades after giving birth, according to a new study. The study, published Monday in the journal JAMA Internal Medicine, found that women who experienced major complications during pregnancy had an increased risk of early death and that risk remained elevated for more than 40 years. The data showed that more than 88,000 women had died and all five pregnancy complications were independently associated with a higher mortality risk later in life. Gestational diabetes was associated with a 52% increased risk of mortality, preterm delivery was associated with a 41% increased risk, delivering a baby with low birth weight was associated with a 30% increased risk, preeclampsia with a 13% increased risk and other hypertensive disorders with a 27% increased risk, the data showed. “We found that the increased mortality was attributable to multiple different causes of death, including heart disease, diabetes, respiratory disorders, and cancer,” he said.

Persons: Dr, Casey Crump, ” Crump, “, ”, Ashley Roman, ” Roman, Crump, Joanne Stone, Raquel, Jaime Gilinski, ” Stone, Sanjay Gupta Organizations: CNN, The University of Texas Health Science Center, Lund University, NYU Langone Health, ’, of Obstetrics, Icahn School of Medicine, CNN Health Locations: UTHealth, Houston, Malmö, Sweden, United States, Mount

☆ There’s still no standard test to detect pancreatic cancer early. Scientists are working to change that
▼ + stars: | 2024-04-08 | by ( Jacqueline Howard | ) edition.cnn.com time to read: +11 min

But there is no standard test to detect early cases of pancreatic cancer, before cancer cells have spread and when surgery is more likely to be helpful. But many studies investigating the potential of liquid biopsy tests for the early detection of pancreatic cancer are still in the early phases. The researchers found that their liquid biopsy approach detected 93% of pancreatic cancers among the US volunteers in their study, 91% of pancreatic cancers in the South Korean cohort and 88% of pancreatic cancers in the Chinese cohort. But there is no blood test that can detect early pancreatic cancer. “Smoking is the most important avoidable risk factor for pancreatic cancer,” according to the American Cancer Society.

Persons: ”, Brian Wolpin, ” Wolpin, “ There’s, Ajay Goel, ” Goel, “, Goel, Al Neugut, Columbia University’s Herbert, Dr, Sanjay Gupta, ” Neugut, “ It’s, It’s, Wolpin Organizations: CNN, Dana, Farber Cancer Institute, US Preventive Services Task Force, American Association for Cancer Research, Hope Comprehensive Cancer Center, Molecular Diagnostics, Therapeutics, Surgeons, University of Pennsylvania, UC San Diego, Columbia, Columbia University’s Herbert Irving Comprehensive Cancer Center, Columbia University Mailman School of Public Health, CNN Health, American Cancer Society Locations: United States, City, Japan, South Korea, China, City of Hope, Hope

☆ First-degree relatives are 9 times more likely to develop a serious form of depression, study says
▼ + stars: | 2024-04-05 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +4 min

CNN —Close relatives of people with treatment-resistant depression are nine times more likely to develop depression that also does not respond to traditional treatment, a new study found. For people with treatment-resistant depression, also known as TRD, standard treatments such as psychiatric therapy and antidepressants may not work well, if at all. Being aware that treatment-resistant depression runs in families can help with early treatment options, experts say. First-degree relatives of people with TRD, which include parents, siblings and children, were nine times as likely to develop treatment-resistant depression and were at high risk of all-cause death and death by suicide compared with relatives of people without TRD, the study found. “So, this is a very welcome study indeed and goes someway to addressing the massive underrepresentation of Asian people in studies.”

Persons: CNN —, ., Ta Li, Yang Ming, ”, Andrew McIntosh, McIntosh, Justin Paget, ” Li, Li, “, ” McIntosh Organizations: Lifeline, CNN, Tung University, Centre, Clinical, Sciences, University of Edinburgh, Digital Locations: Taipei, Taiwan, Scotland, Europe, North America

☆ FDA approves new drug that may help stop and even reverse a rare, fatal condition that doctors call a ‘ticking time bomb’
▼ + stars: | 2024-03-26 | by ( Brenda Goodman | ) edition.cnn.com time to read: +15 min

These proteins cause the walls of a person’s blood vessels to keep growing and thicken over time. As the blood vessels narrow, the heart is forced to work harder to pump blood to the lungs. Treatment with a combination of drugs that dilate, or relax, blood vessels can improve this outlook, but they are not a cure. Both groups were also taking the standard medications for the condition, which help relax blood vessels to improve blood flow. But Galiatsatos said that as promising as the drug looks, there are still many unknowns, including whether the drug will benefit all PAH patients equally.

Persons: Katrina Barry, Barry, “, ”, Winrevair, Merck Winrevair, Vallerie McLaughlin, Panagis, Galiatsatos, isn’t, ” Barry, I’m, fanny, She’s, sotatercept, PAH, Sotatercept, “ There’s, Kristin Highland, Highland, ” Merck, Merck, Dr, Sanjay Gupta, Aaron Waxman, Barry’s, he’s, they’ve, Johnson –, Waxman, “ I’ve, “ It’s, who’ve Organizations: CNN, American Lung Association, US Food and Drug Administration, Merck, FDA, University of Michigan, PAH, Johns Hopkins Bayview Medical Center, New England, of Medicine, Cleveland Clinic, Institute, Clinical, CNN Health, Brigham, Women’s Hospital, Johnson Locations: PAH, American, Greece, Boston

☆ WeightWatchers CEO just sent an internal memo to employees as stock crashes, amid debt concerns, Oprah exit
▼ + stars: | 2024-03-14 | by ( Eric Rosenbaum | ) www.cnbc.com time to read: +6 min

But since then WW shares have suffered heavy selling, dropping to a new 52-week low on Thursday. The stock, due to its debt load and short interest, as well as the general anxiety about the impact of the new weight loss drugs, is subject to heightened volatility. In the memo, Sistani told employees she wanted "to take a moment to address some of the breathless media coverage." WW shares closed at $1.87 on Thursday. It noted that WW was among companies from the weight loss industry involved in the TV event.

Persons: Oprah Winfrey, Sistani, Eli Lilly, Sima Sistani, Guggenheim, Oprah, Winfrey Organizations: CNBC, Nordisk, Guggenheim Partners, Guggenheim, WeightWatchers Clinic, FDA, WeightWatchers, National Museum of, ABC

☆ Orthorexia: The clean eating disorder
▼ + stars: | 2024-03-01 | by ( Madeline Holcombe | ) edition.cnn.com time to read: +7 min

It was 20 years of an eating disorder and the anxiety and stress that comes with it culminating into one moment, he said. But clinicians are seeing a rise in orthorexia among patients, said therapist Jennifer Rollin, founder of The Eating Disorder Center in Rockville, Maryland. Orthorexia is a fixation on eating “clean,” as defined by a set of rules dependent on certain individuals and the context they live in, said Dr. Jennifer Gaudiani, an eating disorder physician and founder and medical director of the Gaudiani Clinic in Denver. When looking at therapy, check for not only an eating disorder specialist, but one with experience with orthorexia, Rollin said. People with orthorexia may find themselves with a team that includes therapists and dietitians, similar to patients in treatment for other eating disorders, Rollin said.

Persons: Jason Wood, pita, Wood, Jennifer Rollin, “, ” Rollin, Orthorexia, Jennifer Gaudiani, it’s, couldn’t, Rollin, Gaudiani, ” Gaudiani, orthorexia, ”, ” Wood, “ I’m, that’s Organizations: CNN, Disorders, Gaudiani Clinic, National Association, orthorexia Locations: Rockville , Maryland, Denver

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