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Taking a high dose of ADHD drugs is linked to more than five times greater risk of developing psychosis or mania, according to a new study published Thursday in the American Journal of Psychiatry. The research is among the first to find a relationship between escalating doses of the drugs — amphetamines, in particular — and a greater likelihood of psychotic symptoms. The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The medium dosage — 20 mg to 40 mg of Adderall, 50 mg to 100 mg of Vyvanse or 15 mg to 30 mg of dextroamphetamine — was linked to a 3.5 times higher risk. There was no increased risk of psychosis with another ADHD drug, Ritalin, which isn’t an amphetamine.

Persons: it’s, ”, Jacob Ballon, hadn’t, Will Cronenwett, ” Cronenwett, Vyvanse, Takeda, Lauren Moran, Brigham, “, ” Moran, Moran, Cronenwett, ” Ballon, they’re Organizations: American, of Psychiatry, Stanford Medicine, Northwestern Medicine, Psychiatry, NBC News, Takeda Pharmaceuticals, . Food, Drug Administration, FDA, Pharmaceuticals, McLean Hospital, Mass Locations: United States, U.S, Boston

☆ Machine Gun Kelly celebrates one year of sobriety
▼ + stars: | 2024-08-06 | by ( Lisa Respers France | ) edition.cnn.com time to read: +1 min

CNN —Machine Gun Kelly is opening up about his sobriety. The rapper and actor spoke with Bunnie Xo’s podcast “Dumb Blonde,” which streamed Monday, where he talked about getting “completely sober from everything.”“I don’t drink anymore. He also shared about the childhood trauma of his father being on trial for the death of his own father, the star’s grandfather. I’m also really hard on myself, very self-deprecating,” Kelly said. “I’m just happy that I’m able to start to be comfortable enough to show people who I am because I kind of depended on my art to do that.”

Persons: Kelly, Bunnie, “, ”, haven’t, ” Kelly, Megan Fox, ” “, I’m, “ I’m Organizations: CNN

☆ A.D.H.D. Startup Executives Accused of $100 Million Fraud in Adderall Scheme
▼ + stars: | 2024-06-13 | by ( Dani Blum | ) www.nytimes.com time to read: +1 min

Tens of thousands of patients with attention deficit hyperactivity disorder nationwide could face disruptions to their care after two executives of a major telehealth company that distributed A.D.H.D. The Department of Justice announced on Thursday that the chief executive and the clinical president of Done, the telehealth company, had been arrested and accused of participating in a scheme to distribute Adderall and other stimulants for A.D.H.D. to patients who did not need the medications, and to bill insurers for these drugs. The charges come amid ongoing shortages of Adderall and another stimulant, Vyvanse. said that as many as 50,000 patients across the nation who rely on Done or similar telehealth platforms to obtain stimulant medications may be affected.

Persons: General Merrick B, Garland Organizations: of Justice, Centers for Disease Control

☆ Japan's Takeda beats Q1 profit estimates on mainstay drugs, dengue vaccine
▼ + stars: | 2023-07-27 | by ( ) www.reuters.com time to read: +2 min

Companies Takeda Pharmaceutical Co Ltd FollowTOKYO, July 27 (Reuters) - Japan's Takeda Pharmaceutical (4502.T) posted first-quarter profit that beat analysts' estimates, citing solid sales of mainstay drugs and the launch of new products including its dengue fever vaccine. Operating profit rose 12% from a year earlier to 168.6 billion yen ($1.2 billion) in the three months through June 30, the drugmaker said. That compared with an average forecast of 150.7 billion yen from six analysts polled by Refinitiv. The company held its forecast for full-year operating profit at 349 billion yen. Analysts expect 481.1 billion yen on average for the year.

Persons: Takeda, Rocky Swift, Tom Hogue, Robert Birsel Organizations: Takeda Pharmaceutical, Refinitiv, Therapeutics, Shire Plc, Nikkei, Thomson Locations: Japan, United States, U.S

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