Southgate stepped up from the U21s to take charge of the senior side following Sam Allardyce's abrupt exit in September 2016 and guided England to the semi-finals of the 2018 World Cup.
The 53-year-old had been Three Lions boss for eight years and exits the role after a fourth major tournament in charge.
The former England defender then led his side to the final of Euro 2020 - which they lost on penalties to Italy at Wembley - before a quarter-final exit at the 2022 World Cup.
His final tournament in charge was this summer, as England were edged out 2-1 by Spain in the final.
England became the first team in the history of the European Championships to lose consecutive finals.
Persons:
Southgate, Sam Allardyce's
Organizations:
U21s, Lions, Italy, Wembley, England
Locations:
England, Spain