The sudden collapse of tech-focussed SVB earlier this month destabilised the sector and drew some of Europe's biggest banking names into investors' focus.
In March, the Stoxx index of European bank shares .SX7P is down more than 18% and the U.S. KBW regional bank index .KRX has lost 21%, with investors on edge about what's next.
In Europe, bank bonds are under pressure and credit default swaps, or the cost of insurance against defaults, uneasily high.
First Citizens said it would take on assets of $110 billion, deposits of $56 billion and loans of $72 billion, and expand in California.
It will share further potential losses with the FDIC and the FDIC retains some $90 billion in securities held for disposal.