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Search resuls for: "The Jackson Laboratory"


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CNN —The origin of modern humans’ long-standing love affair with carbs may predate our existence as a species, according to a new study. The study revealed these genes duplicated long before the advent of agriculture. Without amylase, humans would not be able to digest foods such as potatoes, pasta, rice or bread. The research also revealed duplication of the AMY1 gene existed in the genomes of Neanderthals and Denisovans, an extinct hominin first discovered in 2010 about whom relatively little is known. “This study’s genomic sleuthing is helping to finally time stamp some of those major milestones, and it is revealing tantalizing clues about humanity’s long love affair with starch.”
Persons: , Feyza Yilmaz, , sapiens, AMY1, Taylor Hermes, wasn’t, ” Hermes, , Christina Warinner, John L, Loeb, Warinner Organizations: CNN, The Jackson Laboratory, University of Buffalo, Jackson Laboratory, University of Arkansas, Social Sciences, Harvard University Locations: Farmington , Connecticut, New York
However, over half of the sequences within the Y chromosome, the smallest and most complicated of the 46 human chromosomes, remained unknown. Now, the same group of researchers has filled in the missing information, publishing a complete Y chromosome sequence Wednesday in the journal Nature. “This new analysis will allow us to better understand the regions of the Y chromosome that have regulatory functions and may encode mRNA and proteins.”Many people begin to lose their Y chromosome in some of their cells as they age, particularly those cells that undergo rapid turnover, such as blood cells. Having a complete Y chromosome genetic reference may help scientists and doctors further explore this potential link. “However, it has been questioned whether loss of the Y chromosome is a biomarker of biological aging or whether loss of the Y chromosome has a direct effect on the health of men,” he said.
Persons: , Monika Cechova, Cechova, Kenneth Walsh, ” Walsh, Walsh, it’s, ” Cechova, Charles Lee Organizations: CNN —, University of California, University of Virginia School of Medicine, Human Genome Research, T2T Consortium, Jackson Laboratory, Genomic Medicine Locations: Santa Cruz
Researchers published two new papers on the human Y chromosome. That's because the Y chromosome is "the most complex, most repetitive chromosome," said Monika Cechova, a postdoctoral researcher at the University of California, Santa Cruz. AdvertisementAdvertisementKaren Miga was one of the researchers involved in fully sequencing the human Y chromosome. The worldwide Y chromosomeFor the single-sequence paper, researchers sequenced the Y chromosome of a single individual of European descent, known as the HG002 genome. Because of all the gaps in the Y chromosome genome reference, researchers haven't fully understood how the chromosome contributes to overall health.
Persons: Karen Miga, Monika Cechova, Carolyn Lagattuta, Pascal Gagneux, wasn't, Gagneaux, Evan Eichler, Cechova, Miga, Gagneux, haven't Organizations: Service, Telomere, University of California, UC Santa Cruz, UC San Diego, Center for Academic Research, Human Genome Research Institute, Jackson Laboratory, Genomic Medicine Locations: Wall, Silicon, Nature, Santa Cruz, Anthropogeny
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