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☆ 10 business leaders who spearheaded industry-transforming change in 2024
▼ + stars: | 2024-12-16 | by ( Business Insider | ) www.businessinsider.com time to read: +33 min

Business Insider's annual list of people transforming business highlights these leaders who work in media, finance, technology, transportation, and labor. AdvertisementAmazon's entertainment offerings help keep people subscribing to Prime, the free-delivery service that includes Prime Video and other benefits. Prime Video captured just 3.7% of TV viewing in November, well behind Netflix (7.7%) and YouTube (10.8%), per Nielsen. Still, since most people don't pay for Prime Video as a stand-alone service, it doesn't have the churn problem that dogs other streamers. AdvertisementAmazon cut hundreds of jobs across Prime Video and MGM Studios teams early in 2024.

Persons: that's, Cathy Engelbert, Leon Sinclair, Mike Hopkins, Lisa Miller, Miller, Pete Stavros, KKR's, Stavros, Arthur Sadoun, Groupe Publicis Groupe Sadoun, Sadoun, Leo Burnett, Tony, Tiger, Publicis, Don Draper, quoi, Omnicom, telco Orange, Les Bleues, Caitlin Clark, Angel Reese, Engelbert, Rome wasn't, didn't, there's, Fei, Fei Li, World Labs Greg Sandoval, Li, Justin Johnson, Christoph Lassner, Ben Mildenhall, Andreessen Horowitz, Nvidia's, —, Jensen Huang, Nvidia Tom Williams, ChatGPT, Huang, OpenAI's, Chris Malachowsky, Curtis Priem, Morris Chang, Jensen, Lebaredian, it's Huang, Preqin Preqin Sinclair, Sinclair, Preqin, Marin Gjaja, Ford, Gjaja, Hopkins, it's, Morgan Stanley, Brian Williams, Jennifer Salke's, Nielsen, Varkey, Mayo, Ranjit Kapila, Sallie Mae, Kapila, Eaton Vance, Aperio, Envestnet, we've, Lazard Organizations: Amazon's, MGM Studios, KKR, Apollo, Groupe Publicis Groupe, Groupe, Saatchi & Saatchi, Publicis Conseil, Labour, Epsilon, Interpublic, French men's national, team, Cancer, WNBA, ESPN, Deloitte, NBA, Canadian, World Labs, Princeton, Labs, AMD Ventures, Stanford University's Institute for, Sequoia Capital, Stanford, Google, Nvidia, University of Oregon, AMD, Taiwan Semiconductor Manufacturing Company, Loughborough University, England's Department of Health, Intercontinental Exchange, New York Stock Exchange, IHS, P, BlackRock, Ford Model, Ford, Boston Consulting Group, MGM Studios Prime, Amazon MGM Studios, Hopkins, NFL, Amazon, Ampere, Netflix, NBC, Sony Pictures Television, Hulu, MGM, Starz, Apple, Bloomberg, Prime, YouTube, Video, Mayo Clinic Health, Mayo Clinic, Mayo, Health, University of Minnesota, Yale New, Yale New Haven Health Northeast Medical, Department of Medicine, Preventive, Nasdaq, Citadel, Northwestern University, Franklin, Industry, Fidelity Locations: Preqin, Hawaii, Publicis, Rome, Taiwan, Rugby, England, Amazon, Minnesota, Wisconsin, Mayo, Rochester , Minnesota, Mayo's Rochester, Yale New Haven, Rochester

☆ Alzheimer’s blood test catches 90% of early dementia cases, study finds
▼ + stars: | 2024-07-28 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +10 min

CNN —A combined blood test for cognitive decline has a 90% accuracy rate in determining whether memory loss is due to Alzheimer’s disease, a new study found. “The p-tau217 blood test is turning out to be the most specific for Alzheimer’s and the one with the most validity. “These are absolutely transformational times.”How does a p-tau217 blood test work? The results of the blood tests were then measured against patient diagnoses provided by Swedish primary care doctors and specialists. “There’s no one more bullish on these tests than I am, but Alzheimer’s blood tests aren’t fully definitive yet,” he said.

Persons: CNN —, Sebastian Palmqvist, ” Palmqvist, ”, Maria Carrillo, Carrillo, “ You’re, that’s, ” Carrillo, “, ” Tau tangles, Richard Isaacson, Oskar Hansson, ” Hansson, Hansson, Isaacson, ” Isaacson Organizations: CNN, Lund University, “, Alzheimer’s Association, International Conference Locations: Sweden, Alzheimer’s, Florida, United States, Philadelphia

☆ Does America’s Largest Health Care Company Control Your Doctor’s Office? Help The Times Report
▼ + stars: | 2024-07-10 | by ( Chris Hamby | More About Chris Hamby | ) www.nytimes.com time to read: +1 min

Health care in America is changing. The days of small, independent medical practices have mostly passed. UnitedHealth Group, which owns the nation’s largest insurer, also employs or is affiliated with roughly 90,000 doctors — more than any other company. Through its lesser-known subsidiary Optum, it operates primary care practices, specialty clinics, home health agencies, urgent care centers and other facilities across the country. Step 1: Unsure whether Optum owns or contracts with your clinic?

Persons: Optum Organizations: UnitedHealth, Times Locations: America

☆ Down syndrome families' fight for access to Alzheimer’s trials, treatments
▼ + stars: | 2023-10-10 | by ( Julie Steenhuysen | ) www.reuters.com time to read: +9 min

In an extended portion of Eisai’s main Leqembi trial, CAA was associated with one death. 'THE DIGNITY OF RISK'Hillerstrom said the groups are "very strongly" lobbying Eisai and Lilly to conduct the safety trials in Down syndrome, and said he has been meeting with the companies to push them to design such trials. Lilly declined to comment on whether it is considering either a safety trial or taking part in that study. An Eisai spokeswoman said the company "has no immediate plans" to conduct clinical trials of Leqembi in people with Down syndrome. The company is collaborating with LuMind in a study gathering data on how Alzheimer's manifests in people with Down syndrome.

Persons: Oskar Hillerstrom, Lianor, Hampus, Brian Snyder, Lianor da Cunha, Oskar, de Oeiras, Teresa, Oskar’s, Hampus Hillerstrom, Eli Lilly's, LuMind, Hillerstrom, Lilly, Emily Largent, Beau Ances, Louis, I've, Ances, I'm, Michael Rafii, William Mobley, Mobley, Dawn Brooks, donanemab, Margot Rhondeau, Hannah, Julie Steenhuysen, Caroline Humer, Bill Berkrot Organizations: REUTERS, Rights, Reuters, CAA, University of Pennsylvania Perelman School of Medicine, Medicare, U.S . Food, Drug Administration, Washington University, National Institute, Aging, University of Southern, UC San Diego School of Medicine, LuMind, Syndrome, Thomson Locations: Lexington , Massachusetts, U.S, Santo, Portugal, United States, St, University of Southern California

☆ Hot flashes are more dangerous than previously thought
▼ + stars: | 2023-09-27 | by ( Sandee Lamotte | ) edition.cnn.com time to read: +6 min

Welcome to the hot flashes and other symptoms of approaching menopause — an experience experts say about 75% of women will share if they live long enough. Intense hot flashes could indicate an increased risk of Alzheimer's and heart disease in the future, new research found. The women were also fitted with sweat monitors to record their hot flashes on one of those nights. Frequent moderate to severe hot flashes can often last seven to 10 years, on average, and less frequent or severe hot flashes can last even longer, according to experts. “A lot of people actually underreport their hot flashes, saying they’re not having many when they really are,” Faubion said.

Persons: Peter Dazeley, ”, Stephanie Faubion, Faubion, Rebecca Thurston, “, Thurston, ” Faubion, they’ve, Thurston’s, they’re, Mary Carson Organizations: CNN, Bank, Getty, Mayo, Specialty Clinic, “, University of Pittsburgh’s Pitt Public Health, University of Pittsburgh Locations: Philadelphia, Jacksonville , Florida

But Mintz also acknowledges that having more places to access PrEP likely will not be enough to substantially increase its use in more vulnerable communities. “There needs to be a couple of levers that need to be pulled for everybody to access PrEP who are eligible to access PrEP,” Mintz says. (Joe Raedle/Getty Images)Meanwhile, a pending ruling in a federal appellate court looms as a threat that could more broadly undermine PrEP coverage. “We don’t know what the 5th Circuit could do.”In the wake of the March court ruling, insurers expressed support for preventive services. “Right now, PrEP uptake is quite good among gay white men, but among people of color and among women PrEP access is quite limited,” Dawson says.

Persons: Apretude, ”, Omar Martinez Gonzalez, Sean Bland, we’re, ” Bland, Truvada, ” Martinez Gonzalez, Laura Mintz, Mintz, ” Mintz, Truvada –, AIDSVu, Joe Raedle, Laurie Sobel, “, ” Sobel, Lindsey Dawson, ” Dawson, Torrian Baskerville, Baskerville, ” Baskerville, who’d, Biden, Bland Organizations: U.S . Preventive Services Task Force, U.S . Food, Drug Administration, Affordable, AIDS Foundation Chicago, “, Centers for Disease Control, Santa Clara University School of Law, Georgetown University’s O’Neill Institute for National, Global Health, Blacks, PrEP, Emory University, Gilead Sciences, Black PrEP, Case Western Reserve University School of Medicine, Pride Network of, ViiV Healthcare, GlaxoSmithKline, U.S, Circuit, Appeals, Supreme, Human Rights, Navigators, Department of Health, Human Services Locations: U.S, Black, Cleveland, Gilead, –, Miami, Texas, Ohio

☆ Eye-tracking tool may help diagnose autism more quickly and accurately, new studies suggest
▼ + stars: | 2023-09-05 | by ( Jacqueline Howard | Deidre Mcphillips | ) edition.cnn.com time to read: +10 min

But now, two studies released Tuesday suggest that a recently developed eye-tracking tool could help clinicians diagnose children as young as 16 months with autism – and with more certainty. She was not involved in the new studies, but her research focuses on early diagnosis of autism. The children were enrolled in the study between April 2018 and May 2019, and the eye-tracking tool was included in the assessments. Among the children, 335 had an autism diagnosis that their clinicians were “certain” of without using the eye-tracking tool. “There remains work to be done before an eye-tracking test is used in clinical practice.

Persons: ”, Warren Jones, Rather, ’, Whitney Guthrie, Guthrie, “ They’re, ” Jones, –, Ami Klin, Marcus, ” Klin, Kristin Sohl, ” Sohl, Sohl, Dr, Sanjay Gupta, Geraldine Dawson, “, ” Dawson Organizations: CNN, Marcus Autism, Children’s Healthcare, Autism, Emory University School of Medicine, US Food and Drug Administration, Children’s, Philadelphia’s Center, Autism Research, JAMA, Marcus Autism Center, University of Missouri School of Medicine, American Academy of Pediatrics, US Centers for Disease Control, Devices, Get CNN, CNN Health, Duke Center for Autism, Brain Locations: Atlanta, United States, –, North Carolina

Overall, an FDA spokesperson says that “trial participants should reflect the population that is likely to use the product if FDA-approved. Across a group of 10 novel cancer therapies approved by the FDA in 2022, data shows the share of Black participants in key clinical trials ranged from zero to 8%. “Access to clinical trials at the sites where patients are living is an important factor to changing the landscape,” Perez says. “There’s been some novel ways to recruit patients, like using the church and using barbershops to recruit Black patients,” Cho says. Haddad says a number of Mayo patients were receiving experimental therapies through clinical trials when the pandemic began.

Persons: ”, Leslie Cho, Robert, Suzanne Tomsich, it’s, Edith Perez, Bolt Biotherapeutics, ” Perez, Eli Lilly, “, Lilly “, they’ll, Craig Lipset, ” Lipset, ” Cho, “ There’s, Dr, Tufia Haddad, Haddad, Mayo, Jennifer Dahne, Larry Hawk, Hawk Organizations: Women’s Cardiovascular, Cleveland Clinic, of Cardiovascular Medicine, U.S . Food, Drug Administration, FDA, “, Health, Committee, Cancer, Janssen Pharmaceuticals, Centers for Disease Control, Research Alliance, Mayo Clinic Comprehensive Cancer Center, Care, Mayo’s Center for Digital Health, College of Medicine, Medical University of South, of Psychology, University, Buffalo, SUNY, JAMA Locations: U.S, Chicago, Dallas, Los Angeles, Philadelphia, Los Angeles County, Alaska, “, Medical University of South Carolina

CARE Hospitals Group, according to another investor source, is in talks to sell a 70% stake to U.S. investment giant Blackstone (BX.N) in a deal valued at $800 million. MORE ATTRACTIVE THAN EVERAs government hospitals became increasingly overburdened and incomes rose in India's vast middle class, demand for private healthcare rose over the years. "The India healthcare opportunity has always been attractive, but never more than now. In 2022, PE investors spent $3.2 billion buying stakes in hospitals in India. "Big private hospitals are more reliable," said 35-year-old G. Chavan said as he accompanied his wife to see a doctor.

Persons: Rana Mehta, PwC's, Atlantic, Indira, Blackstone, Gaurav Sharma, Investcorp, Nishant Sharma, Sharma, Chavan, Sriram, Aditya Kalra, Simon Cameron, Moore Organizations: PwC, General Atlantic, CARE Hospitals, Blackstone, CARE, Kedaara Capital, ASIA'S PACE, Temasek, Reuters Graphics, Apollo Hospitals, Thomson Locations: India, PUNE, Pune, Indira, Bahrain, Mumbai, Manipal, Asia

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