It is likely to affect most of the bank's major divisions, with its investment banking arm facing the deepest cuts, a source told Reuters this month.
"We know this is a difficult time for people leaving the firm," a Goldman Sachs statement on Wednesday said.
Last year was challenging across groups including credit, equities, and investment banking broadly, said Paul Sorbera, president of Wall Street recruitment firm Alliance Consulting.
[1/3] A trader works at the Goldman Sachs stall on the floor of the New York Stock Exchange, April 16, 2012.
Shares of Goldman Sachs have partially recovered from a 10% fall last year.