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Arizona Attorney General Kris Mayes said Sunday that she has “no intention” of dropping the criminal case against a group of President-elect Donald Trump’s allies who sought to overturn the results of the 2020 election in Arizona. “I have no intention of breaking that case up. I have no intention of dropping that case,” Mayes, a Democrat, told MSNBC’s Ali Velshi. Those charged include big names like former Trump attorney Rudy Giuliani and former Trump White House chief of staff Mark Meadows. The case is set to go to trial in 2026, but the defendants have sought to have the case dismissed.

Persons: Kris Mayes, Donald Trump’s, “, ” Mayes, MSNBC’s Ali Velshi, ”, Trump, Joe Biden, Rudy Giuliani, Mark Meadows, Giuliani, Kelli Ward, Michael Ward, Sen, Anthony Kern, Robert Montgomery, Samuel Moorhead, Nancy Cottle, Loraine Pellegrino, Greg Safsten, Christina Bobb, Tyler Bowyer, Arizona committeeman Organizations: Electoral College, Trump, Trump White House, Cochise County GOP, Republican Party, Arizona GOP, Republican National, Arizona Locations: Arizona, Cochise County

Jenna Ellis, right, and Sydney Powell, attorneys for President Donald Trump, conduct a news conference at the Republican National Committee on lawsuits regarding the outcome of the 2020 presidential election on Thursday, November 19, 2020. Former Trump campaign attorney Jenna Ellis has agreed to cooperate with prosecutors in Arizona in their criminal cases against so-called fake electors and others who tried to reverse the 2020 election loss of former President Donald Trump, state Attorney General Kris Mayes said Monday. "I am grateful to Ms. Ellis for her cooperation with our investigation and prosecution." "Her insights are invaluable and will greatly aid the State in proving its case in court," the attorney general said. The remaining defendants are Kelli Ward, Tyler Bowyer, Nancy Cottle, Jacob Hoffman, Anthony Kern, James Lamon, Robert Montgomery, Samuel Moorhead, Lorraine Pellegrino, Gregory Safsten, and Michael Ward.

Persons: Jenna Ellis, Sydney Powell, Donald Trump, Kris Mayes, Ellis, Mayes, Rudy Giuliani, Joe Biden, Mark Meadows, John Eastman, Boris Epshteyn, Christina Bobb, Mike Roman, Trump, Kelli Ward, Tyler Bowyer, Nancy Cottle, Jacob Hoffman, Anthony Kern, James Lamon, Robert Montgomery, Samuel Moorhead, Lorraine Pellegrino, Gregory Safsten, Michael Ward Organizations: Republican National Committee, Trump, Prosecutors, New, New York City, Trump White House Locations: Arizona, American, New York

☆ Woman who received pig kidney transplant and heart pump dies
▼ + stars: | 2024-07-09 | by ( Maya Davis | ) edition.cnn.com time to read: +3 min

CNN —Lisa Pisano, the first person to receive a mechanical heart pump as well as a gene-edited pig kidney, died Sunday, according to NYU Langone Health, where she had the surgery. Her case was the first reported organ transplant in a person with a mechanical heart pump, NYU Langone said, the second known transplant of a gene-edited pig kidney into a living recipient and the first transplanted along with the animal’s thymus gland. Pisano was brave and altruistic, Dr. Robert Montgomery, director of the NYU Langone Transplant Institute, said in a statement Tuesday. Due to Pisano’s heart failure and end-stage kidney disease that required routine dialysis, she couldn’t have a standard transplant, NYU Langone said in a news release. The pig kidney she received was genetically altered to evade human antibodies, which typically detect and attack foreign organs.

Persons: CNN — Lisa Pisano, Pisano, NYU Langone, Robert Montgomery, ”, Montgomery, … Lisa, Dr, Sanjay Gupta, ” Montgomery, Pisano’s Organizations: CNN, NYU Langone Health, NYU, NYU Langone Transplant, Procurement, Transplantation Network, US Food and Drug Administration, CNN Health

☆ Transplanted Pig Kidney Is Removed From Patient
▼ + stars: | 2024-06-04 | by ( Roni Caryn Rabin | More About Roni Caryn Rabin | ) www.nytimes.com time to read: 1 min

Surgeons removed the kidney of a genetically engineered pig from a critically ill patient last week after the organ was damaged by inadequate blood flow related to a heart pump that the woman had also received, according to officials at NYU Langone Transplant Institute. The patient, Lisa Pisano, 54, who is still hospitalized, went back on kidney dialysis after the pig’s organ was removed. She lived with the transplanted organ for 47 days, Dr. Robert Montgomery, director of the institute, said. The kidney showed no signs of organ rejection. “Lisa is in stable condition, and her left ventricular assist device is still functioning,” Dr. Montgomery said, referring to the heart pump.

Persons: Lisa Pisano, Robert Montgomery, “ Lisa, Dr, Montgomery, Lisa, ” Organizations: NYU Langone Transplant

☆ Transplant patient stable and on dialysis after pig organ removed due to ‘unique challenges’ with heart, kidney health
▼ + stars: | 2024-05-31 | by ( Amanda Sealy | ) edition.cnn.com time to read: +4 min

CNN —A genetically engineered pig kidney has been removed from a transplant patient after it started losing function, according to a statement on Friday from NYU Langone Health. Lisa Pisano looks at photos of her dog after her surgeries at NYU Langone Health in New York on Monday, April 22, 2024. Shelby Lum/AP/FILEThe kidney had to be removed due “unique challenges in managing both her cardiovascular health and kidney function” 47 days after the transplant, NYU Langone Health said. Pisano family/NYU Langone Health“Lisa is a pioneer and a hero in the effort to create a sustainable option for people waiting for an organ transplant. While the kidney ultimately had to be removed from Pisano, Montgomery said the kidney would be studied for further insights and stressed the importance of her contribution to the larger goal.

Persons: Lisa Pisano, Pisano, NYU Langone, Shelby Lum, ”, Robert Montgomery, Todd, Lisa, Dr, Sanjay Gupta, It’s, Montgomery, and, “ Lisa, ” Montgomery, CNN’s Katherine Dillinger Organizations: CNN, NYU Langone Health, NYU, NYU Langone Transplant Institute, Procurement, Transplantation Network, CNN Health, US Food and Drug Administration Locations: Lisa Pisano of New Jersey, New York, Montgomery, Pisano

☆ More people need transplants than there are organ donors. Pigs might offer a solution
▼ + stars: | 2024-01-30 | by ( Jen Christensen | ) edition.cnn.com time to read: +23 min

The need for more transplant organs is immense and growing. Researchers have transplanted genetically modified pig kidneys and hearts into people who were brain-dead to test whether they work in humans. Although Larry Faucette was too sick for a human heart transplant, University of Maryland doctors said he seemed physically strong enough for a genetically modified pig heart. It was more than a decade after the first heart transplant but long before such procedures became relatively routine. “We learned that the pig heart is an adequate substitute for a human heart.

Persons: Lawrence Faucette, Ann, he’d, ” Ann, Larry Faucette, Ann Faucette Ann, Larry, didn’t, ”, Robert Montgomery, “, Shelby Lum, ” Montgomery, Xenotransplantation, Art Caplan, Caplan, Babe ”, ” Caplan, They’re, eGenesis, people’s, Dr, Mike Curtis, Sanjay Gupta, ” Curtis, hasn’t, Julie O’Hara, Jim Parsons, Jayme Locke, couldn’t, Locke, Parsons, NYU —, Montgomery —, O’Hara, ” Locke, David Bennett Sr, Mary, David Jr, Bartley Griffith, Bennett, they’ve, Muhammad M, Mohiuddin, Larry Faucette’s, David Bennett’s, ” Griffith, xenotransplantation Ann Faucette, Wilbur, White’s, Ann Faucette, NYU ethicist Caplan, they’re, NYU’s Montgomery, UAB’s Locke, Steve Wood, ’ Curtis, “ I’m, it’s, ” O’Hara, Bennett’s, Larry Faucette —, ” Bennett’s, Faucette, who’d, Griffith, would’ve, Kate, Lucy, Nadia Kounang Organizations: CNN, Food and Drug Administration, University of Maryland, FDA, National Institute of Allergy, NYU Langone Transplant Institute, NYU Langone's Transplant, NYU Grossman School, Medicine’s Department of Population Health, “ Disney, University of Alabama, Transplant Institute, Parsons Family, Birmingham, NYU, University of Maryland School of Medicine, Doctors, University of Maryland Medical Center, Uno, UAB, CNN Health, NFL Locations: Frederick , Maryland, United States, Montgomery, “, Midwest, Yucatan, Maryland

It marked the longest a genetically modified pig kidney has ever functioned inside a human, albeit a deceased one. “Two months is a lot to have a pig kidney in this good a condition. Political Cartoons View All 1160 ImagesSo-called xenotransplantation attempts have failed for decades — the human immune system immediately destroyed foreign animal tissue. Montgomery gambled that maintaining Miller's body on a ventilator for two months to see how the pig kidney worked could answer some of those questions. She recently got a card from a stranger in California who's awaiting a kidney transplant, thanking her for helping to move forward desperately needed research.

Persons: gurney, Maurice “ Mo ” Miller, “, Dr, Robert Montgomery, Montgomery, ”, Mary Miller, Duffy, Miller, ” Miller, Sue Duffy, Montgomery’s, immunologist Massimo Mangiola, Jeffrey Stern, Karen Maschke, Mangiola Organizations: NYU Langone, Food and Drug Administration, Associated Press, University of Maryland, FDA, NYU, Hastings Center, Associated Press Health, Science Department, Howard Hughes Medical Institute’s Science, Educational Media Group, AP Locations: Newburgh , New York, California

☆ Two research teams detail advancements in transplanting pig kidneys to humans, marking key steps on path to clinical trials
▼ + stars: | 2023-08-16 | by ( Deidre Mcphillips | ) edition.cnn.com time to read: +5 min

CNN —New advancements in transplanting pig kidneys to humans, detailed by two separate research teams on Wednesday, mark key steps forward in the evolving field of xenotransplantation, the use of non-human tissues or organs to treat medical conditions in humans. Both research teams used genetically modified pig kidneys that were transplanted into recipients experiencing brain death in what is considered pre-clinical human research. Other studies have demonstrated that this can occur when pig kidneys are transplanted in non-human primates. The team has been monitoring pig kidney transplants in a brain-dead decedent – a man named Maurice Miller, known as Mo, who died of a brain tumor – for nearly two months. “Over the last 20 years, we’ve gained a lot of information about how pig kidneys work to replace the functions in primates.

Persons: ”, Jayme Locke, Locke, ” Locke, NYU Langone, Maurice Miller, Mo, Robert Montgomery, Dr, Sanjay Gupta, “ We’re, Adam Griesemer, we’ve, ’ –, we’re Organizations: CNN, University of Alabama, Birmingham Heersink School of Medicine, New York University, Health, Comprehensive Transplant Institute, ”, UAB, NYU, NYU Langone Transplant Institute, CNN Health, Liver Transplant, FDA, US Department of Health, Human, Transplantation Network

☆ About 17 Americans die waiting for transplants each day. Scientists are trying to make more organs in 5 creative ways.
▼ + stars: | 2022-10-18 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +11 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute. Hanna started a company called Renewal Bio to pursue the possibility of turning stem cells into organs for transplants.

☆ 5 cutting-edge medical experiments could expand our organ supply, from gene-edited pigs to artificial embryos
▼ + stars: | 2022-09-24 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +10 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." While much of the shortage is driven by imperfect logistics and bureaucracy rather than supply, cutting-edge research could make organs — human, pig, or synthetic — more accessible in Graham's lifetime. If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute.

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