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A pig has tested positive for H5N1 bird flu in a backyard farm in Oregon. The H5N1 bird flu was detected in a pig in Oregon, the first instance of a swine infection in the US, officials announced on Wednesday. Pigs get both bird flu viruses and human flu viruses, making them a genetic mixing bowl where H5N1 could gain genetic mutations that help it spread between humans. AdvertisementWhy pig infection could be a tipping pointPigs play host to both bird flu viruses and human flu viruses. Inside a pig, the H5N1 bird flu virus could pick up genetic mutations that help it adapt to better infect human bodies.
Persons: , Stacey Schultz, Cherry, Jude Children's, Jeremy Farrar, Diego Vara, Florian Krammer, Cynthia Goldsmith, Jackie Katz, Schultz, Richard Webby, Jude, Robert Giroux Organizations: Service, St, Jude Children's Research, World Health Organization, Reuters, US Department of Agriculture, USDA, Icahn, of Medicine, STAT, CDC, AP, WHO Locations: Oregon, South America, Sao Jose, Norte, Brazil, New York, St, New York City
The Summary Four new presumed cases of bird flu in farmworkers in Washington state bring the U.S. total to 31. Washington is the sixth state to report human cases of bird flu, which has spread rampantly in wild birds, poultry and cattle. Six health workers exposed to the patient reported respiratory symptoms. Webby said the virus’ spread in cows for the past 10 months has raised experts’ level of concern because cows are mammals and interact with humans frequently. Itle said cases in poultry were not unexpected in Washington state, because migrating birds passed through during summer and early fall.
Persons: , Amber Itle, It’s, Umair Shah, Shah, depopulating, Itle, Richard Webby, Missouri —, Webby, Jude Children’s, Milk, Peter Rabinowitz, Rabinowitz Organizations: for Disease Control, CDC, World Health Organization, Center, Studies, Jude Children’s Research, Research, University of Washington, One Health Locations: farmworkers, Washington, Franklin County, Missouri, Memphis , Tennessee, U.S
Read previewBird flu is flying wild, and it has many infectious disease experts more worried now than ever. The H5N1 avian influenza virus has killed tens of millions of birds across the planet and more than 40,000 sea lions and seals. Most people seem to have very little chance, if any, of catching H5N1 avian influenza right now. Jim Vondruska/ReutersBut infectious disease experts are increasingly concerned that the H5N1 virus could make a sustained jump into humans and start spreading among us. This virus is a leading candidate for the next pandemic, and four developments in the past month have experts worried.
Persons: , Jim Vondruska, That's, Dr, Monica Gandhi, Bird, WHO —, Christopher Dye, Dye, David L, Ryan, Gandhi, Tayfun, Rick Bright, Cynthia Goldsmith, Jackie Katz, Richard Webby, Jude, Talita, Lima Freitas, Amanda Perobelli, Marko Geber, Terry Chea, they've Organizations: Service, CDC, Business, Global Medicine, University of California, Health Organization, WHO, University of Oxford, Boston Globe, Getty, US Department of Agriculture, Anadolu Agency, The Telegraph, Biomedical, Research, Development Authority, AP, Centre, Studies, Reference Laboratory, World Organization for Animal Health, Vaccines, University of Pennsylvania Locations: Luz, Monee , Illinois, San Francisco, Australia, Kolkata, India, New Mexico, New York, St, Michigan, Campinas, Brazil
Then, three healthy ferrets were placed in the same enclosures with three of the sick animals. These animals could touch, nose and lick the sick animals, and all of them became ill.Next, the CDC tested airborne transmission by putting three healthy ferrets into an enclosure where they could breathe the same air as sick animals but couldn’t touch them. In her lab, ferrets with previous exposures to seasonal flu strains didn’t get as sick when exposed to new flu viruses compared to those with no prior exposure to seasonal strains. How much help we might get from past exposures to flu viruses is difficult to predict, however, which is why vaccination would still be important to tune up our immunity. They never spread the virus to any of the other animals in the facility — including themselves.
Persons: Mark Naniot, Naniot, , , It’s, Jeremy Farrar, Jesse Bloom, Fred Hutch, ” Naniot, Naniot hadn’t, Scott Weese, Weese, there’s, Covid, Rick Bright, Sanjay Gupta, Bright, Erin Sorrell, Zahl, Seema Lakdawala, hasn’t, ” Bright, Dr, Richard Webby, Jude Children’s, “ It’s, Ducks, Michael Osterholm, “ I’ve, he’s Organizations: CNN, Swiss Army, World Health Organization, Fred Hutch Cancer Center, University of Guelph, US Centers for Disease Control, CDC, Research, Development Authority, CNN Chief, Bright Global Health, Johns Hopkins Center for Health Security, Getty, Emory University, STAT, Administration, Strategic Preparedness, USDA, Jude Children’s Research, Infectious Disease, University of Minnesota, CNN Health Locations: Wisconsin’s, United States, Seattle, Canada, Texas, Vadso, Finnmark, Norway, AFP, Finland, St, Wisconsin
The H5N1 virus has become a pandemic among animals, raging through worldwide bird populations and now through US cattle herds. There, the H5N1 virus can continue operating as an avian virus, grabbing avian receptors with no need to adapt to human receptors. Two previous one-off human cases of H5N1 — one in Chile and one in Ecuador — featured respiratory symptoms. Even with its current monitoring, the CDC would probably detect sustained human spread, he said. Correction — June 4, 2024: An earlier version of this story misstated the nature of genomic sequencing of the H5N1 virus.
Persons: , Jude virologist Richard Webby, Diego Vara, Rick Bright, Amanda Perobelli, John Harper, Nirav Shah, farmworkers, Shah, Bright, Bill Powers, Nathan Howard, Department of Agriculture hadn't Organizations: Service, US Centers for Disease Control, Business, CDC, Reuters, World Health Organization, Studies, New York Times, Stock, Drug Administration, STAT, Webby, Department of Agriculture Locations: Texas, Michigan, Americas, Norte, Brazil, Chile, Ecuador, Campinas, Townsend , Delaware
Federal regulators have discovered fragments of bird flu virus in roughly 20 percent of retail milk samples tested in a nationally representative study, the Food and Drug Administration said in an online update on Thursday. Samples from parts of the country that are known to have dairy herds infected with the virus were more likely to test positive, the agency said. Regulators said that there is no evidence that this milk poses a danger to consumers or that live virus is present in the milk on store shelves, an assessment public health experts have agreed with. But finding traces of the virus in such a high share of samples from around the country is the strongest signal yet that the bird flu outbreak in dairy cows is more extensive than the official tally of 33 infected herds across eight states. “It suggests that there is a whole lot of this virus out there,” said Richard Webby, a virologist and influenza expert at St. Jude Children’s Research Hospital.
Persons: , Richard Webby, Jude Children’s Organizations: Food and Drug Administration, Regulators, St, Jude Children’s Research
CNN —The bird flu spreading through cattle in the United States is an “enormous concern” the chief scientist of the World Health Organization said Thursday as he called for more tracking and preparation for the virus. So far, there is no evidence that the highly pathogenic H5N1 flu virus can spread from person to person. Though H5N1 doesn’t spread from person to person, humans can catch it when they’re exposed to infected animals. They are only the second documented case of human H5N1 in the United States. The US Centers for Disease Control and Prevention says that while the current risk to public health from H5N1 is low, it is monitoring the situation carefully.
Persons: Dr, Jeremy Farrar, , Richard Webby, , hasn’t, Sanjay Gupta Organizations: CNN, World Health Organization, WHO, Research, Get CNN, CNN Health, US Department of Agriculture’s, Plant Health, Services, US Centers for Disease Control, CDC Locations: United States, British, Geneva, Texas, Colorado, St, — Texas, New Mexico , Kansas, South Dakota , Idaho , Michigan , Ohio, North Carolina
LONDON, Feb 24 (Reuters) - The World Health Organization is working with Cambodian authorities after two confirmed human cases of H5N1 bird flu were found among one family in the country. The U.N. health agency last assessed the risk to humans from avian flu as low earlier this month. "The global H5N1 situation is worrying given the wide spread of the virus in birds around the world and the increasing reports of cases in mammals including humans," Briand said. WHO-affiliated labs already hold two flu virus strains that are closely related to the circulating H5N1 virus that manufacturers can use to develop new shots if needed. A global meeting of flu experts this week suggested developing another strain that more closely matches H5N1 clade 2.3.4.4b, Webby said in the briefing.
They say the attributes that have made this virus thrive in wild birds likely make it less infectious to people. Although the exact changes required for a bird flu virus to become easily transmissible in people are not known, a pair of landmark studies done a decade ago offer some clues. Mink have both avian and human-type receptors, but avian receptors are scarce in humans and located deep in the lungs. That change is a must if a bird flu virus is to spread easily in people. None of the experts discounted the possibility that H5N1 or another avian flu virus could mutate and spark a pandemic, and many believe the world has not seen its last flu pandemic.
Just How Bad Is the ‘Tripledemic’?
  + stars: | 2022-12-16 | by ( Amy Schoenfeld Walker | ) www.nytimes.com   time to read: +6 min
R.S.V., or respiratory syncytial virus, has made so many young children ill this fall that weekly pediatric hospitalizations for R.S.V. Public health officials have been warning for weeks that a “tripledemic” of Covid-19, flu and R.S.V. Weekly hospitalizations for Covid-19, R.S.V. With flu surging and Covid-19 circulating, respiratory illness has overwhelmed pediatric units across the country, shifting the strain to emergency rooms and children’s hospitals. The predominant type of flu circulating right now, a subtype of influenza A known as H3, also tends to result in higher flu hospitalizations among the elderly, according to the C.D.C.
În timpul pandemiei COVID-19 a existat o transmisibilitate atât de redusă a gripei, încât unele tipuri de virusuri gripale s-ar putea să fi dispărut. Interesant este că două tipuri de virusuri gripale nu au mai apărut nicăieri în lume de un an, nefiind raportate cazuri de îmbolnăvire din cauza acestora, scrie Live Science. Două familii de virusuri gripale cauzează gripa sezonieră: gripa A și gripa B. Virusurile gripale A sunt împărțite în „subtipuri” bazate pe două proteine de pe suprafața lor cunoscute sub numele de hemagglutinină (H) și neuraminidază (N), potrivit Centrului pentru Controlul Bolilor. Virusurile gripale B, pe de altă parte, nu au subtipuri, dar sunt împărțite în două ramuri cunoscute sub numele de B - Yamagata și B - Victoria. Cât de mult va fi schimbată și cât de mult timp va rămâne așa, acestea sunt întrebările principale.
Persons: Victoria, Trevor Bedford, Florian Krammer, Richard Webby Organizations: Medicină, Organizației Mondiale a Sănătății ( OMS Locations: Yamagata, Seattle, New York
Sursa foto: Jurnal.mdDouă tulpini de virusuri gripale ar fi dispărut; Ele nu au mai fost semnalate de un an de zile nicăieri în lumeÎn timpul pandemiei COVID-19 a existat o transmisibilitate atât de redusă a gripei, încât unele tipuri de virusuri gripale s-ar putea să fi dispărut. Două tipuri de virusuri gripale nu au mai apărut nicăieri în lume de un an, nefiind raportate cazuri de îmbolnăvire din cauza acestora, scrie Live Science. Două familii de virusuri gripale cauzează gripa sezonieră: gripa A și gripa B. Virusurile gripale A sunt împărțite în „subtipuri” bazate pe două proteine ​​de pe suprafața lor cunoscute sub numele de hemagglutinină (H) și neuraminidază (N), potrivit Centrului pentru Controlul Bolilor. Virusurile gripale B, pe de altă parte, nu au subtipuri, dar sunt împărțite în două ramuri cunoscute sub numele de B - Yamagata și B - Victoria. Cât de mult va fi schimbată și cât de mult timp va rămâne așa, acestea sunt întrebările principale.
Persons: Victoria, Richard Webby Organizations: Organizației Mondiale a Sănătății ( OMS Locations: Yamagata
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